Optimizes biomarker selection for cost-effective treatment rules.
problem Incorporating multiple biomarkers in treatment selection rules can be costly and reduce model performance.
method Developed procedures for estimating linear and nonlinear combinations of biomarkers using 0-norm penalized weighted classification.
result Demonstrated the importance of feature selection and marker cost in treatment selection rules.
Selective imputation improves treatment effect estimation from missing data.
problem Missing data complicates treatment effect estimation, especially with treatment variables.
method Introduced mixed confounded missingness (MCM) and selective imputation.
result Selective imputation provides unbiased treatment effect estimates.
The paper develops methods to estimate treatment effects in sample selection models.
problem Evaluation of treatments when outcomes are only observed for a subpopulation due to sample selection or attrition.
method Combines selection-on-observables and instrumental variable assumptions with double machine learning for treatment evaluation.
result Proposed estimators are asymptotically normal and root-n consistent.
Kernel ridge regression for causal inference with missing data.
problem Estimating treatment effects with missing data in selected samples.
method Kernel ridge regression estimators for nonparametric dose response curves and semiparametric treatment effects.
result Uniform consistency and finite sample rates for continuous treatment, root-n consistency for discrete treatment.
FSRM method improves treatment effect estimation from observational data.
problem Estimating treatment effects from observational data with missing counterfactual outcomes and selection bias.
method FSRM method based on deep representation learning and matching, which maps covariate space into a selective, nonlinear, and balanced representation space.
result FSRM method outperforms state-of-the-art methods in estimating treatment effects.
New method selects best HTE estimator without ground-truth treatment effects.
problem Selecting best HTE estimator from multiple candidates.
method Cross-fitted, exponentially weighted test statistic with two-way sample splitting.
result Empirically, reliable error control and reduced false selections.
Variable selection for optimal treatment regime in a clinical trial or an observational study is getting more attention. Most existing variable selection techniques focused on selecting variables that are important for prediction, therefore some variables that are poor in prediction but are critical for decision-making…
Method estimates treatment effects with continuous values, correcting for confounding.
problem Estimating treatment effects with continuous values, dealing with confounding.
method Two-stage kernel ridge regression: first stage learns response, second stage corrects for distribution shift.
result Optimal learning bounds achieved without estimating treatment density, adapts to unknown overlap and kernel spectral decay.
Investigates model selection challenges in heterogeneous treatment effect estimation.
problem Lack of validation metrics for choosing the best model in treatment effect estimation.
method Empirical investigation of different model selection criteria.
result Complex interplay between selection strategies, estimators, and data.
Proposes a new method to find features affecting treatment effect distribution.
problem Existing methods fail to detect differences in treatment effect distribution parameters other than the mean.
method Formulates and estimates a feature importance measure that quantifies feature influence on potential outcome distribution discrepancies. Develops a feature selection algorithm to control type I error rate.
result Successfully discovers important features and outperforms existing mean-based methods.
New method improves reliability of selecting individuals based on predicted treatment effects.
problem Reliability of selecting individuals based on predicted conditional average treatment effects (CATE) is unreliable.
method Denoised Conformal Alignment, combining proxy errors, variance estimation, and Benjamini-Hochberg selection.
result Significantly improved power in selecting individuals while maintaining false discovery rate control.
TCFimt forecasts causal effects of multiple interventions from individual data.
problem Estimating causal effects of temporal multi-interventions from individual data.
method TCFimt uses adversarial tasks in seq2seq framework to alleviate bias and contrastive learning to decouple effects.
result TCFimt outperforms state-of-the-art methods in predicting future outcomes and choosing optimal treatments.
Paper improves feature selection for predicting outcomes from observational data.
problem Feature selection for post-intervention outcome prediction from pre-intervention variables in healthcare settings.
method Extends Markov boundary concept to treatment-outcome pairs, uses observational and experimental data.
result Combining observational and experimental data improves feature selection and effect estimation.
Reduces selection bias in estimating individual treatment effects.
problem Selection bias in counterfactual reasoning.
method Auto-encoder with regularized loss based on Pearson Correlation Coefficient.
result Improves performance in estimating individual treatment effects.
Estimates and infers multi-stage stationary treatment policies with variable selection.
problem Valid inference for multi-stage stationary treatment policies with high-dimensional feature variables.
method Estimate the value function using augmented inverse probability weighted estimator, apply penalty for variable selection, construct one-step improvements for valid inference.
result Improved estimators are asymptotically normal, valid inference for policy parameters demonstrated.
Enhances credit card limit adjustments by considering treatment uncertainty and prediction criteria.
problem Optimal treatment selection under multitreatment scenarios.
method Proposes a comprehensive methodology incorporating conditional value-at-risk and prediction criterion for continuous outcomes.
result Significantly improved policy performance in credit card limit adjustments.
Method estimates treatment effect bounds in sample selection models.
problem Estimating heterogeneous treatment effects in presence of sample selection.
method Debiased/double machine learning approach for non-linear and high-dimensional confounders.
result Substantially tighter effect bounds for younger users.
The paper shows how expert knowledge can improve treatment effect estimation.
problem Lack of leveraging expert knowledge in treatment effect estimation.
method Formally defining two types of expertise (predictive and prognostic) and demonstrating their influence on treatment effect estimation methods.
result Expertise type significantly influences treatment effect estimation methods, and can be predicted from a dataset.
The paper introduces a new model to correct bias in treatment effect estimates due to sample selection.
problem Bias in treatment effect estimates due to sample selection.
method Type 2 Tobit Bayesian Additive Regression Trees (TOBART-2) with Dirichlet Process Mixture distribution and soft trees.
result Corrects bias in treatment effect estimates by accounting for nonlinearities and model uncertainty.
New framework minimizes interference and selection bias in network A/B testing.
problem Interference and selection bias in network A/B testing.
method Proposes a principled framework that jointly minimizes interference and selection bias using edge spillover probability and cluster matching.
result Significantly lower error in causal effect estimation compared to existing solutions.
The paper uses double machine learning to estimate dynamic treatment effects robustly.
problem Estimating causal effects of dynamic treatments with time-varying covariates.
method Double machine learning with Neyman-orthogonal score functions for robustness.
result Asymptotic normality and n \sqrt{n} n -consistency of the estimators under specific conditions. New feature selection methods improve uplift modeling accuracy.
problem Overfitting and poor interpretability in feature selection for uplift models.
method Explicitly designed feature selection methods inspired by statistics and information theory.
result Proposed methods outperform traditional feature selection methods in uplift modeling.
CFR-Pro enhances treatment effect estimation by incorporating local proximity.
problem Treatment selection bias in HTE estimation from observational data.
method Proximity-enhanced CounterFactual Regression (CFR-Pro) with pair-wise proximity regularizer and subspace projector.
result Significantly outperforms competitors in HTE estimation accuracy.
Propensity score (PS) based estimators are increasingly used for causal inference in observational studies. However, model selection for PS estimation in high-dimensional data has received little attention. In these settings, PS models have traditionally been selected based on the goodness-of-fit for the treatment mech…
CAPITAL algorithm identifies optimal patient subgroups for better treatment.
problem Identify maximum number of patients benefiting from better treatment.
method Constrained Policy Tree Search (CAPITAL) algorithm to find optimal subgroup selection rule (SSR).
result Maximizes the number of patients with enhanced treatment effects.
A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be predicted through an unknown relationship that depends on the patient information …
Proposes ESCFR to estimate treatment effects from biased data.
problem Treatment selection bias in observational data.
method Stochastic optimal transport with relaxed mass-preserving and proximal factual outcome regularizers.
result Significantly better performance in estimating treatment effects.
Optimizes subgroup selection in clinical trials.
problem Identifying regions in feature space where a regression function exceeds a threshold.
method Formulates subgroup selection as constrained optimisation, determining minimax optimal rate for regret.
result Determines the minimax optimal rate for regret in sample size and Type I error probability.
MDCN improves treatment effect estimation in multicenter observational studies.
problem Incongruities in multicenter observational studies due to center-specific protocols and treatment reactions.
method MDCN learns a new feature embedding to address selection bias and strengthen information sharing between similar centers.
result MDCN provides more accurate treatment insights for new, unobserved centers compared to existing methods.
This chapter introduces flexible methods for policy evaluation.
problem Assessing the causal effect of treatments or interventions.
method Review of various evaluation methods including randomized, observational, and machine learning approaches.
result Flexible methods for handling many observations and covariates.
In this paper, we provide efficient estimators and honest confidence bands for a variety of treatment effects including local average (LATE) and local quantile treatment effects (LQTE) in data-rich environments. We can handle very many control variables, endogenous receipt of treatment, heterogeneous treatment effects,…
A new method corrects weight values to improve treatment effect estimation.
problem Estimating heterogeneous treatment effects in high-dimensional data with sample selection bias.
method Differentiable Pareto-Smoothed Weighting (DPSW) framework.
result Our method outperforms existing methods in treatment effect estimation.
CRL approach improves understanding of heterogeneous treatment effects in complex diseases.
problem Estimating heterogeneous treatment effects in complex diseases.
method Causal rule learning (CRL) workflow consisting of rule discovery, selection, and analysis.
result CRL outperforms other methods in providing interpretable estimates of HTE.
The estimation of optimal treatment regimes is of considerable interest to precision medicine. In this work, we propose a causal k k k -nearest neighbor method to estimate the optimal treatment regime. The method roots in the framework of causal inference, and estimates the causal treatment effects within the nearest neig…
This paper enhances uplift modeling for multi-treatment marketing campaigns.
problem Optimizing marketing strategies by selecting individuals likely to respond to different treatments.
method Leveraging score ranking and calibration techniques.
result Improves overall performance of marketing campaigns.
New method uses few instruments to estimate complex causal effects.
problem Estimating causal effects with limited instruments in high-dimensional settings.
method Sequentially selects and combines instruments to estimate the treatment effect.
result Can reliably recover the treatment effect's projection onto the instrumented subspace.
Estimates causal effects using machine learning for binary treatment and mediator.
problem Estimating direct and indirect quantile treatment effects under selection-on-observables.
method Double/debiased machine learning estimators based on efficient score functions.
result Uniform consistency and asymptotic normality of effect estimators.
Survival forests estimate treatment effects with censored data.
problem Estimating treatment effects in survival analysis with censored data.
method Causal survival forests using orthogonal estimating equations.
result Survival forests perform well relative to baselines in treatment effect estimation.
Bayesian method corrects bias in estimating average treatment effects from observational data.
problem Estimating average treatment effects from observational data with selection bias and missing counterfactuals.
method Data-driven modification to an arbitrary prior based on the propensity score to correct for posterior bias.
result Significant improvement in estimation accuracy and uncertainty quantification compared to unmodified priors.
Chiseling finds valid subgroups interactively, improving on existing methods.
problem Finding valid subgroups with inferential guarantees in regression and causal inference.
method Interactive subgroup refinement with inferential validity guarantees.
result Chiseling identifies better subgroups than existing methods with inferential guarantees.
Selective deconfounding improves ATE estimation with less data.
problem Estimating ATE with unobserved confounders using limited data.
method Combining confounded and deconfounded observational data for ATE estimation.
result Selective deconfounding can significantly reduce the amount of deconfounded data needed.
Optimizes experimental design using synthetic controls for better outcomes.
problem Estimating average treatment effects in studies with pre-treatment data.
method Mixed-integer programming for selecting treated and control units and weights.
result Improves mean squared error and statistical power compared to simple alternatives.
Improves treatment effect estimation by reducing sample size needed.
problem Estimating causal treatment effects from observational data requires many covariates, increasing sample size.
method Proposes a nonconvex joint sparsity regularization objective function to recover a sparse subset of covariates.
result Improves sample complexity to scale with the size of the sparse subset and log of the total covariates.
Given two possible treatments, there may exist subgroups who benefit greater from one treatment than the other. This problem is relevant to the field of marketing, where treatments may correspond to different ways of selling a product. It is similarly relevant to the field of public policy, where treatments may corresp…
RATE metrics evaluate treatment prioritization rules, subsuming existing methods.
problem Comparing and testing the quality of treatment prioritization rules.
method Rank-weighted average treatment effect (RATE) metrics.
result RATE metrics enable asymptotically exact inference in various study settings.
Sepsis is the leading cause of mortality in the ICU. It is challenging to manage because individual patients respond differently to treatment. Thus, tailoring treatment to the individual patient is essential for the best outcomes. In this paper, we take steps toward this goal by applying a mixture-of-experts framework …
CRN model estimates treatment effects over time using adversarial balancing.
problem Estimating treatment effects over time in medical settings.
method Adversarial domain balancing to remove time-varying confounders.
result CRN achieves lower error in estimating counterfactuals and treatment timing.
Proposes DR-ME test for interpretable distributional treatment effects.
problem Detects invisible differences in treatment effects on distributional outcomes.
method Semiparametrically efficient finite-location test using kernel witnesses and orthogonal features.
result DR-ME reveals causal-discrepancy coordinates and has noncentral chi-square local power.