A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
Efficiently fine-tunes patient-independent seizure detection models with tensor kernel machine.
New model identifies patient-specific disease root causes.
Personalized models explain TB treatment outcomes considering patient context.
Multi-output Gaussian processes (GPs) are a flexible Bayesian nonparametric framework that has proven useful in jointly modeling the physiological states of patients in medical time series data. However, capturing the short-term effects of drugs and therapeutic interventions on patient physiological state remains chall…
Identifies patient-specific root causes of disease using structural equation models.
Deep CNN-RNN model classifies breathing sounds for respiratory disease diagnosis.
FalconBC improves patient-specific cardiovascular modeling by estimating boundary conditions efficiently.
Accurate models of patient survival probabilities provide important information to clinicians prescribing care for life-threatening and terminal ailments. A recently developed class of models - known as individual survival distributions (ISDs) - produces patient-specific survival functions that offer greater descriptiv…
Proposes a framework for personalized treatment recommendations using observational data.
Proposes a tool to contrast global vs personalized models in clinical prediction.
An accurate model of patient-specific kidney graft survival distributions can help to improve shared-decision making in the treatment and care of patients. In this paper, we propose a deep learning method that directly models the survival function instead of estimating the hazard function to predict survival times for …
Machine learning predicts trauma patient mortality risk.
Continuous Glucose Monitoring (CGM) has enabled important opportunities for diabetes management. This study explores the use of CGM data as input for digital decision support tools. We investigate how Recurrent Neural Networks (RNNs) can be used for Short Term Blood Glucose (STBG) prediction and compare the RNNs to con…
New definition of patient-specific root causes of disease using counterfactuals.
Widespread adoption of electronic health records (EHRs) has fueled the development of using machine learning to build prediction models for various clinical outcomes. This process is often constrained by having a relatively small number of patient records for training the model. We demonstrate that using patient repres…
Adaptive prediction timing improves healthcare outcomes by predicting patient events at the right frequency.
We develop a personalized real time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs. Heterogeneity of the patients population is captured via a hierarchical latent class model. The proposed algorithm aims t…
Survival month for non-small lung cancer patients depend upon which stage of lung cancer is present. Our aim is to identify smoking specific gene expression biomarkers in the prognosis of lung cancer patients. In this paper, we introduce the network elastic net, a generalization of network lasso that allows for simulta…
We present a personalized and reliable prediction model for healthcare, which can provide individually tailored medical services such as diagnosis, disease treatment, and prevention. Our proposed framework targets at making personalized and reliable predictions from time-series data, such as Electronic Health Records (…
Model identifies key problems in HIV patients' records.
Paper addresses data heterogeneity in federated learning for CoxPH models in healthcare.
Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing preventive measures are potential solutions to improve cancer patients's quality of …
FRESH combines patient-level and aggregate-level data for better clinical decision making.
Deep learning model creates patient representations for scalable EHR-based stratification.
Parkinson's disease is a neurodegenerative disorder characterized by the presence of different motor impairments. Information from speech, handwriting, and gait signals have been considered to evaluate the neurological state of the patients. On the other hand, user models based on Gaussian mixture models - universal ba…
GRU-D detects age-specific missing patterns in vital signs.
Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an interpretable and generalizable model for early mortality prediction in elderly patients wi…
Deep model integrates MRI and DTI for autism severity prediction.
Framework predicts clinical severity from rs-fMRI data using network optimization.
New model captures patient-level EHR data efficiently.
Distributed representations have been used to support downstream tasks in healthcare recently. Healthcare data (e.g., electronic health records) contain multiple modalities of data from heterogeneous sources that can provide complementary information, alongside an added dimension to learning personalized patient repres…
Objective: Predict patient-specific vitals deemed medically acceptable for discharge from a pediatric intensive care unit (ICU). Design: The means of each patient's hr, sbp and dbp measurements between their medical and physical discharge from the ICU were computed as a proxy for their physiologically acceptable state …
Most approaches to machine learning from electronic health data can only predict a single endpoint. Here, we present an alternative that uses unsupervised deep learning to simulate detailed patient trajectories. We use data comprising 18-month trajectories of 44 clinical variables from 1908 patients with Mild Cognitive…
Objective: We investigate whether deep learning techniques for natural language processing (NLP) can be used efficiently for patient phenotyping. Patient phenotyping is a classification task for determining whether a patient has a medical condition, and is a crucial part of secondary analysis of healthcare data. We ass…
Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have increased since the millennium change. MIMIC-III, a freely accessible critical care data…
New test identifies specific biological parameters for personalized CVD detection.
Objectives: Most cancer data sources lack information on metastatic recurrence. Electronic medical records (EMRs) and population-based cancer registries contain complementary information on cancer treatment and outcomes, yet are rarely used synergistically. To enable detection of metastatic breast cancer (MBC), we appl…
Bayesian meta-learning improves health prediction models across similar diseases.
Machine learning approaches have been effective in predicting adverse outcomes in different clinical settings. These models are often developed and evaluated on datasets with heterogeneous patient populations. However, good predictive performance on the aggregate population does not imply good performance for specific …
Traditional medicine typically applies one-size-fits-all treatment for the entire patient population whereas precision medicine develops tailored treatment schemes for different patient subgroups. The fact that some factors may be more significant for a specific patient subgroup motivates clinicians and medical researc…
Paper shows Cox model optimisation leaks patient data in distributed learning.
Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia - high blood glucose (BG). Patients must also be careful not to inject too much insulin because this could induce hypoglycemia (low BG), which can potentially be fatal. Patients therefore follow a …
Sparse GFA identifies disease factors in FTD subgroups.
Prediction models can harm patients even when accurate, leading to self-fulfilling prophecies.
Patient journeys are compared to find clusters of similar disease trajectories.
We describe a novel neural network architecture for the prediction of ventricular tachyarrhythmias. The model receives input features that capture the change in RR intervals and ectopic beats, along with features based on heart rate variability and frequency analysis. Patient age is also included as a trainable embeddi…
MSB framework improves survival prediction in immunotherapy patients with missing data.
CLOCS uses contrastive learning to improve cardiac signal representations.