Research
On-device research index

arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,657 papers · 148 categories

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1223 · Jun 201919922001200920172026
48 results for patient-specific

Efficiently fine-tunes patient-independent seizure detection models with tensor kernel machine.

problem Improving seizure detection accuracy for wearable devices.
method Transfer learning with tensor kernel machine using canonical polyadic decomposition.
result Patient fine-tuned model achieves high performance with smaller model size.

New model identifies patient-specific disease root causes.

problem Identifying root causes of complex diseases varying between patients.
method Generalized Root Causal Inference (GRCI) algorithm for heteroscedastic noise model.
result GRCI accurately extracts patient-specific root causes.

New definition of patient-specific root causes of disease using counterfactuals.

problem Lack of rigorous mathematical formulation for automatic detection of root causes.
method Proposes a counterfactual definition matching clinical intuition and uses Shapley values for causal contribution scores.
result Adapts to disease prevalence, accounts for noisy labels, and admits fast computation.

FalconBC improves patient-specific cardiovascular modeling by estimating boundary conditions efficiently.

problem Efficiently estimating boundary conditions in patient-specific cardiovascular models, especially in open-loop models and anatomies with lesions.
method A general amortized inference framework based on probabilistic flow that treats clinical targets and anatomies as conditioning variables.
result Demonstrated on two patient-specific models, FalconBC improves efficiency and accuracy in estimating boundary conditions.

Identifies patient-specific root causes of disease using structural equation models.

problem Detecting significant variables in complex diseases that differ between patients.
method Defining patient-specific root causes as exogenous errors in a structural equation model, quantifying predictivity using Shapley values, and developing a fast algorithm called Root Causal Inference.
result Significant improvements in accuracy by uncovering root causes with large effect sizes at the individual level but clinically insignificant effect sizes at the group level.

Deep CNN-RNN model classifies breathing sounds for respiratory disease diagnosis.

problem Automated diagnosis of respiratory diseases using wearable devices.
method Patient-specific model tuning and local log quantization of weights.
result 71.81% accuracy on leave-one-out validation with patient-specific data.

Accurate models of patient survival probabilities provide important information to clinicians prescribing care for life-threatening and terminal ailments. A recently developed class of models - known as individual survival distributions (ISDs) - produces patient-specific survival functions that offer greater descriptiv…

2019-06-25abs ↗pdf ↗

An accurate model of patient-specific kidney graft survival distributions can help to improve shared-decision making in the treatment and care of patients. In this paper, we propose a deep learning method that directly models the survival function instead of estimating the hazard function to predict survival times for …

2017-05-29abs ↗pdf ↗

Deep model integrates MRI and DTI for autism severity prediction.

problem Predicting spectrum-level deficits in autism using multimodal brain imaging.
method Generative deep-learning framework combining rs-fMRI and DTI data.
result Hybrid model outperforms existing methods in predicting autism severity.

The paper integrates AI and expert knowledge to optimize radiotherapy decisions.

problem Optimizing radiation dose planning considering patient-specific information.
method Integrating Gaussian process models with deep neural networks to quantify uncertainty.
result Improves AI model performance and guides clinical decision making.

Framework predicts clinical severity from rs-fMRI data using network optimization.

problem Predicting clinical severity from rs-fMRI data.
method Joint network optimization framework combining sparse subnetworks and linear regression.
result Framework outperforms standard methods and identifies clinically relevant ASD networks.

Hybrid pipeline detects spike-and-wave discharges in long-term EEG recordings.

problem Manual identification of spike-and-wave discharges in long-term EEG recordings is labour-intensive and error-prone.
method A hybrid pipeline that combines analytical features with a shallow ANN for SWD detection.
result The method correctly detected 384 out of 392 annotated SWD events, achieving high sensitivity and specificity.

Generative adversarial network system improves ECG arrhythmia classification.

problem Improving automatic ECG arrhythmia classification accuracy.
method Generative adversarial network with patient-specific normal beats and generated abnormal beats.
result Superior overall classification performance for SVEB and VEB on MIT-BIH arrhythmia database.

Proposes a tool to contrast global vs personalized models in clinical prediction.

problem Balancing global vs personalized models in clinical prediction.
method Localized regression approach using autoencoder for dimension reduction.
result Identification of patient subgroups where global models fall short.

A deep learning framework segments deep cerebellar nuclei from 7T MRI, improving accuracy and consistency.

problem Challenging to accurately segment small deep cerebellar nuclei using standard MRI protocols.
method Proposes DCN-Net, a deep learning framework that encodes contextual information and handles imbalanced data.
result Improves segmentation accuracy and consistency compared to existing methods.

Proposes a framework for personalized treatment recommendations using observational data.

problem Estimating patient-level treatment effects from observational data.
method Integrates existing methods for learning patient-level causal models.
result Improves patient outcomes in heart failure patients with acute kidney injury.

In this work we propose a method to compute continuous embeddings for kmers from raw RNA-seq data, without the need for alignment to a reference genome. The approach uses an RNN to transform kmers of the RNA-seq reads into a 2 dimensional representation that is used to predict abundance of each kmer. We report that our…

2018-10-08abs ↗pdf ↗

Mathematical conditions and practical computations for adversarial robustness measures are established.

problem Existence, uniqueness, and scalability of adversarial robustness measures for AI classifiers.
method Formulated and proven mathematical conditions for existence, uniqueness, and explicit analytical computation of minimal adversarial paths and distances. Practical computation demonstrated on various AI tools and synthetic benchmarks.
result Explicit mathematical conditions and practical computations for adversarial robustness measures are established.

Missing data is a common problem in real-world settings and particularly relevant in healthcare applications where researchers use Electronic Health Records (EHR) and results of observational studies to apply analytics methods. This issue becomes even more prominent for longitudinal data sets, where multiple instances …

2018-12-02abs ↗pdf ↗

LI-ITR combines flexible ML with interpretable approximations for personalized treatment rules.

problem Combining flexibility and interpretability in personalized treatment rules.
method Uses variational autoencoders and a mixture of interpretable experts.
result Accurately recovers true local coefficients and optimal treatment strategies.

In medicine, both ethical and monetary costs of incorrect predictions can be significant, and the complexity of the problems often necessitates increasingly complex models. Recent work has shown that changing just the random seed is enough for otherwise well-tuned deep neural networks to vary in their individual predic…

2019-06-10abs ↗pdf ↗

DeepCoDA provides personalized interpretability for complex health data.

problem Interpreting complex health data, especially compositional data, is challenging.
method DeepCoDA framework for high-dimensional compositional data, personalized interpretability through patient-specific weights.
result DeepCoDA maintains state-of-the-art performance and provides coherent, personalized interpretations.

SepVAE separates patient-specific patterns from healthy ones using contrastive VAE.

problem Separating patient-specific patterns from healthy ones in medical datasets.
method SepVAE uses a contrastive VAE with disentangling and classification losses to differentiate between common and salient features.
result SepVAE outperforms previous methods in three medical applications and a CelebA dataset.

Proposes a method to estimate personalized treatments from high-dimensional data.

problem Estimating individualized treatment regimes (ITRs) from high-dimensional covariates.
method Directly targets the contrast between potential outcomes, using dimension-reduced outcome-weighted learning.
result Achieves universal consistency, converging to the Bayes risk under mild conditions.

A new algorithm uses concavity in Gaussian processes to optimize decisions in bandit problems.

problem Optimizing decisions in sequential problems with context-dependent rewards.
method Proposes a UCB algorithm using a shape-constrained reward function estimator based on a Gaussian Process model with concavity constraints.
result Derives regret bounds for the proposed UCB algorithm.

A new framework optimizes fMRI and behavioral data for better understanding of Autism.

problem Linking complex fMRI data to behavioral measures is challenging.
method Coupled manifold optimization framework projecting fMRI onto a shared manifold and mapping to behavioral measures.
result Framework outperforms traditional methods in predicting clinical severity of Autism.

The field of precision medicine aims to tailor treatment based on patient-specific factors in a reproducible way. To this end, estimating an optimal individualized treatment regime (ITR) that recommends treatment decisions based on patient characteristics to maximize the mean of a pre-specified outcome is of particular…

2019-02-05abs ↗pdf ↗

The paper estimates personalized treatment effects in medical settings with competing risks.

problem Estimating treatment effectiveness for specific events in the presence of alternative event types.
method Meta-learners combining Cox regression or random survival forests for risk modeling and elastic net regression or random forests for direct CATE modeling.
result Compared meta-learners in multiple simulation settings, providing practical guidance for model selection.

NOTMAD estimates context-specific Bayesian networks without breaking datasets.

problem Non-convexity of acyclic graphs limits sharing information between context-specific estimators.
method NOTMAD models context-specific Bayesian networks as mixtures of archetypal DAGs, estimating structures and parameters jointly.
result NOTMAD shares information between context-specific acyclic graphs, enabling single-sample resolution.

We consider a problem of ranking and selection via simulation in the context of personalized decision making, where the best alternative is not universal but varies as a function of some observable covariates. The goal of ranking and selection with covariates (R&S-C) is to use simulation samples to obtain a selection p…

2017-10-07abs ↗pdf ↗

CoI framework models clinical feature interactions, revealing temporal dependencies and enhancing transparency.

problem Capturing latent, time-varying dependencies among clinical features in time-series data.
method Chain-of-Influence (CoI) framework constructs an explicit, time-unfolded graph of feature interactions.
result Achieves state-of-the-art predictive performance (AUROC of 0.960 on CKD progression and 0.950 on ICU mortality).

Proposes a new Q-learning method for survival outcomes in clinical trials.

problem Incomplete follow-up data and nonlinear covariate effects in clinical trials.
method Combines Buckley-James boosting with flexible base learners for estimating optimal treatment regimes.
result Improves treatment decision accuracy and stability in longitudinal clinical trials.