A new method for brain tissue segmentation across medical centers using a smoothness prior.
problem Tissue segmentation challenges due to center-specific acquisition protocols.
method Developed a smoothness prior that is fit to segmentations from another medical center, integrated into an unsupervised Bayesian model.
result Segmentations are similarly smooth across centers, improving generalization.
New deep learning model generates accurate personalized human head models for electromagnetic dosimetry.
problem Challenges in generating accurate human head models for personalized electromagnetic dosimetry.
method Proposed ForkNet architecture for segmentation of whole human head structures using deep learning.
result Generated head models exhibit strong matching with manual segmentation results.
MRAI-NET learns MRI scanner-independent features for better tissue segmentation.
problem Invariance of MRI voxelwise classifiers across different scanners.
method Siamese neural network to extract acquisition-invariant feature vectors.
result MRAI-NET outperforms traditional classifiers in small sample settings.
Study uses deep learning to quickly estimate tissue properties for personalized radio-frequency dosimetry.
problem Time-consuming tissue segmentation limits personalized radio-frequency dosimetry.
method Developed a learning-based approach using Convolutional Neural Networks (CNN) for magnetic resonance images.
result Smooth distribution of dielectric properties improves SAR distribution consistency.
Paper proposes a neural network for estimating brain conductivity without segmentation.
problem Accurate head model generation for personalized TMS with realistic conductivity.
method Convolutional neural network estimating conductivity from MRI data.
result Smooth electric field results similar to conventional methods without segmentation.
DeepMRSeg uses deep learning for brain tissue segmentation.
problem Automated segmentation of brain tissues and abnormalities.
method Modified UNet architecture with multi-scale feature extraction.
result DeepMRSeg achieves high accuracy on various brain segmentation tasks.
Paper presents a brain tumor segmentation method using NGMM and 3D FVF.
problem Automatic brain tumor segmentation from MRIs is challenging.
method Normalized Gaussian Bayesian classifier and 3D Fluid Vector Flow algorithm.
result The method successfully segments brain tumors from MRI images.
Novel framework for medical image segmentation using deep learning.
problem Class imbalance and domain adaptation in medical image segmentation.
method Biophysics-based domain adaptation and automatic segmentation of white, gray, and cerebrospinal fluid.
result Improved segmentation performance, especially with the biophysics-based domain adaptation.
Applying deep learning methods to mammography assessment has remained a challenging topic. Dense noise with sparse expressions, mega-pixel raw data resolution, lack of diverse examples have all been factors affecting performance. The lack of pixel-level ground truths have especially limited segmentation methods in push…
Improved MRI head anatomy segmentation using deep learning with multiple priors.
problem Challenges in segmenting head anatomy in MRI, especially with lesions.
method Added three types of prior information to a 3D convolutional network: spatial priors, morphological priors, and spatial context.
result Multiprior network improves segmentation performance, especially for abnormal anatomies.
Deep learning improves medical ultrasound image segmentation accuracy.
problem Improving accuracy in medical ultrasound image segmentation.
method Categorizes deep learning methods into six groups and analyzes current representative algorithms.
result Current methods show significant improvement in image segmentation accuracy.
Bayesian layer improves image segmentation and out-of-distribution detection.
problem Outlier detection in image segmentation.
method Parameter-efficient hierarchical convolutional Gaussian Processes in Wasserstein-2 space.
result Uncertainty estimates improve out-of-distribution detection.
Many real-world vision problems suffer from inherent ambiguities. In clinical applications for example, it might not be clear from a CT scan alone which particular region is cancer tissue. Therefore a group of graders typically produces a set of diverse but plausible segmentations. We consider the task of learning a di…
Local semi-supervised method improves brain tissue classification in child MRI.
problem Inaccurate detection of brain tissue classes due to intensity variations in early developing brains.
method Kernel Fisher Discriminant Analysis (KFDA) combined with SSIM for perceptual image quality assessment.
result Optimal brain partitioning into subdomains with different average intensity values and separating surfaces between brain parts.
Novel method embeds generative model into Bayesian optimization for HD cardiac model parameter estimation.
problem High-dimensional optimization of patient-specific cardiac model parameters with limited data.
method Embeds a generative variational auto-encoder into the objective function of Bayesian optimization.
result Improves accuracy of parameter estimation with more than 10x gain in efficiency.
This paper reviews deep learning for multi-modality medical image segmentation.
problem Improving segmentation accuracy in medical images using multiple modalities.
method Overview of deep learning and multi-modal medical image segmentation, analysis of different network architectures and fusion strategies.
result Later fusion of modalities can lead to more accurate segmentation results.
Algorithm segments glandular structures in colon histology images for cancer grading.
problem Manual gland segmentation is time-consuming and risky for patients.
method Local intensity and texture features, Random Forest classifier, multilevel approach.
result Fast, accurate automatic gland segmentation for clinical use.
A method for MRI brain tumor segmentation using feature vectors and kernel dictionary learning.
problem Segmenting brain tumor regions in MRI images.
method Extracting feature vectors, training kernel dictionaries, and selecting informative feature vectors.
result The method outperforms other methods in segmentation accuracy and reduces training time.
A CNN integrates with Markov random fields for brain segmentation.
problem Combining CNNs and probabilistic models for robust brain segmentation.
method Backpropagation-based recurrent CNN for spatial interactions in Markov random fields.
result Model generalizes across different imaging protocols.
Proposes a FoE prior for improving CNN performance in distribution shifts.
problem Improving CNN performance in image analysis tasks with distribution shifts.
method Uses a field-of-experts (FoE) prior to match feature distributions of test and training images.
result Outperforms previous TTA methods in lesion segmentation and most healthy tissue segmentation tasks.
Deep CNNs segment prostate from MRI images.
problem Variability and scarcity of annotated prostate MRI data.
method Two-step CNN approach: global bounding box, local delineation; data augmentation.
result State-of-the-art Dice scores (90.6) on PROMISE12 dataset.
Paper tackles brain tumor segmentation using weak labels and hierarchical training.
problem High manual labeling effort for fully supervised brain tumor segmentation.
method Uses scribbles and global labels for weak supervision, trains two networks in phases.
result Achieves competitive results on brain tumor segmentation and substructure segmentation.
New method fills MS lesions more realistically and naturally.
problem Lesions in MS brain scans bias morphometric analyses.
method Non-local partial convolutions (NLPC) integrating Unet-like network and non-local module.
result NLPC generates inpainted regions that appear more realistic and natural.
Lung segmentation accuracy varies little across diverse datasets.
problem Limited clinical applicability of automated lung segmentation methods.
method Comparison of four deep learning approaches and two standard algorithms on diverse datasets.
result Standard U-net approach yields higher accuracy on routine imaging data.
Supervised learning has been very successful for automatic segmentation of images from a single scanner. However, several papers report deteriorated performances when using classifiers trained on images from one scanner to segment images from other scanners. We propose a transfer learning classifier that adapts to diff…
A tool simplifies neural network training for medical image analysis.
problem Difficulties in training neural networks for medical image analysis.
method Intuitive interface for WSI annotation and display, human-in-the-loop strategy.
result Improved network performance through iterative annotation.
Graph convolutional networks refine organ segmentation using uncertainty analysis.
problem Challenges in organ segmentation due to variability and tissue similarity.
method Uncertainty analysis of graph convolutional networks for semi-supervised learning.
result Improved segmentation accuracy (1% for pancreas, 2% for spleen) compared to state-of-the-art methods.
Motivation: Understanding functions of proteins in specific human tissues is essential for insights into disease diagnostics and therapeutics, yet prediction of tissue-specific cellular function remains a critical challenge for biomedicine. Results: Here we present OhmNet, a hierarchy-aware unsupervised node feature le…
Automatic segmentation of auditory ossicles from CT images using Ricci curvature.
problem Automatic diagnosis of ossicles' diseases from 3D CT images of the head.
method Proposes a completely automatic method that locates and segments ossicles without manual labels or templates, using Ricci curvature in an energy function.
result Performance of the proposed method using discrete Forman-Ricci curvature is superior to state-of-the-art methods.
Gene expression levels in a population vary extensively across tissues. Such heterogeneity is caused by genetic variability and environmental factors, and is expected to be linked to disease development. The abundance of experimental data now enables the identification of features of gene expression profiles that are s…
Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor magnetic resonance imaging (MRI) can directly image tissue attenuation properties…
Machine learning classifies colorectal tissue using photoacoustic microscopy.
problem Traditional diagnostic methods for colorectal cancer are limited in detail and painful.
method Machine learning applied to acoustic resolution photoacoustic microscopy.
result Machine learning accurately classified benign and malignant tissue.
PathologyGAN learns deep representations of cancer tissue images.
problem Limited high-quality labels for cancer tissue images.
method Developed a GAN framework for unsupervised learning of cancer tissue phenotypes.
result Generated high-quality images with interpretable latent space.
Deep learning network matches radiologists in breast cancer segmentation.
problem Automating radiologist-level cancer segmentation from breast MRI.
method 3D U-Net architecture trained on 382,290 breast scans, compared to 255,500 benign cases.
result Network performance matched radiologists' on 2D segmentation of breast cancers.
Model learns cancer tissue images onto a low-dimensional space revealing tissue characteristics.
problem Improving cancer diagnosis through high-fidelity digital pathology.
method Deep generative model using PathologyGAN to map real images onto a latent space.
result Latent space encodes morphological characteristics and reveals distinct tissue clusters.
Automated detection of MS lesions improves to 67% with 7T MRI.
problem Accurate detection of small, scarce cortical lesions in MS patients.
method 3D U-Net with brain tissue segmentation, supervised training on 7T MRI.
result 67% lesion detection rate with 42% false positives.
Automatically classifying the tissues types of Region of Interest (ROI) in medical imaging has been an important application in Computer-Aided Diagnosis (CAD), such as classification of breast parenchymal tissue in the mammogram, classify lung disease patterns in High-Resolution Computed Tomography (HRCT) etc. Recently…
This paper uses CNNs to automatically segment ischaemic stroke lesions from MRI sequences.
problem Automatically segmenting ischaemic stroke lesions from MRI sequences is challenging.
method Adversarial training of CNNs on multi-sequence MRI data.
result The method achieves high Dice scores for core and penumbra segmentation.
Bayesian Gaussian Processes layer detects out-of-distribution data in medical imaging.
problem Detecting out-of-distribution data in medical imaging tasks.
method Parameter-efficient hierarchical convolutional Gaussian Processes in Wasserstein-2 space.
result Uncertainty estimates enable superior out-of-distribution detection compared to previous methods.
This study assesses ML methods for brain tumor segmentation and survival prediction.
problem Segmenting and predicting outcomes of brain tumors with varying sub-regions and heterogeneous properties.
method Evaluation of state-of-the-art machine learning algorithms on BraTS challenge datasets.
result Identification of best ML algorithms for brain tumor segmentation and survival prediction.
Cellina uses supervised disentanglement to predict cell behavior in tissues.
problem Querying counterfactuals on tissue graphs
method Cellina framework using supervised disentanglement
result Outperforms spatially-informed and non-spatial competitors
2D tissue model predicts neurotoxicity more accurately and robustly.
problem Fast and accurate prediction of developmental neurotoxicity.
method Machine learning on 2D bio-engineered tissue models.
result 2D model outperforms 3D model in accuracy and robustness.
Universal model for soft tissue mechanics under shock waves.
problem Modeling shock wave mechanics in soft biological tissues.
method Continuum mixture theory with phase-field mechanics.
result Universal thermodynamically consistent formulation for soft porous tissues.
New method to estimate doctors' effort in annotating medical images.
problem High effort and expense in annotating medical images.
method Proposes a new criterion to evaluate effort, uses active learning and U-shape network for annotation strategy, and fine annotation platform to reduce effort.
result State-of-the-art segmentation performance achieved with only 60% annotation candidates, reducing effort by 44-47%.
Transfer learning from breast histopathology improves prostate cancer detection.
problem Insufficient prostate histopathology datasets for training.
method Transfer learning from breast histopathology images.
result Proposed approach outperforms transfer learning from ImageNet dataset.
A deep learning method automates tensioning for surgical tissue cutting.
problem Automating tensioning for surgical tissue cutting to improve accuracy and reliability.
method Deep reinforcement learning for modeling an autonomous tensioning planner.
result The proposed method outperforms existing methods in terms of performance and robustness.
The paper presents the application of Variational Autoencoders (VAE) for data dimensionality reduction and explorative analysis of mass spectrometry imaging data (MSI). The results confirm that VAEs are capable of detecting the patterns associated with the different tissue sub-types with performance than standard appro…
Despite great advances, molecular cancer pathology is often limited to the use of a small number of biomarkers rather than the whole transcriptome, partly due to computational challenges. Here, we introduce a novel architecture of Deep Neural Networks (DNNs) that is capable of simultaneous inference of various properti…