Variable selection for optimal treatment regime in a clinical trial or an observational study is getting more attention. Most existing variable selection techniques focused on selecting variables that are important for prediction, therefore some variables that are poor in prediction but are critical for decision-making…
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48 results for “sequential treatment selection”
The paper addresses treatment recommendation problems by optimizing distributional characteristics.
problem Optimizing treatment recommendations based on distributional targets.
method Characterizes the problem's difficulty and proposes near-optimal policies.
result Characterizes the difficulty of the problem and proposes near-regret optimal policies.
New method uses few instruments to estimate complex causal effects.
problem Estimating causal effects with limited instruments in high-dimensional settings.
method Sequentially selects and combines instruments to estimate the treatment effect.
result Can reliably recover the treatment effect's projection onto the instrumented subspace.
In treatment allocation problems the individuals to be treated often arrive sequentially. We study a problem in which the policy maker is not only interested in the expected cumulative welfare but is also concerned about the uncertainty/risk of the treatment outcomes. At the outset, the total number of treatment assign…
New method estimates treatment effects over time with unobserved confounders.
problem Estimating treatment effects from observational data with unobserved confounders.
method Sequential Deconfounder using Gaussian process latent variable model.
result Unbiased estimates of individualized treatment responses over time.
A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be predicted through an unknown relationship that depends on the patient information …
DARTS optimizes covariate selection in trials with limited data.
problem Limited budget for high-dimensional pretreatment data.
method Dynamic Adaptive Rerandomization via Thompson Sampling (DARTS).
result DARTS efficiently concentrates budget on informative features.
The paper develops methods to estimate optimal treatment sequences under policy constraints.
problem Estimating the best sequence of treatments over multiple stages for individuals.
method Empirical welfare maximization approach, solving treatment assignment sequentially or simultaneously.
result Established convergence rates and upper bounds for estimation methods.
Proposes methods for learning optimal dynamic treatment regimes robust to unconfoundedness violations.
problem Estimating optimal dynamic treatment regimes using historical observational data when unconfoundedness is violated.
method Utilizes proximal causal inference framework to propose three nonparametric identification methods, a (K+1)-robust method, and establish a semiparametric efficiency bound.
result Establishes the (K+1)-robust method for learning optimal dynamic treatment regimes, validating its efficiency and multiple robustness through numerical experiments.
The paper addresses estimating long-term treatment effects with monotone missing data.
problem Estimating long-term treatment effects with missing data, especially monotone missing.
method The paper introduces the sequential missingness assumption for identification and proposes three novel estimation methods: inverse probability weighting, sequential regression imputation, and SeqMSM. It also introduces a balancing-enhanced approach, BalanceNet, to improve estimation accuracy.
result The proposed methods, including BalanceNet, effectively estimate long-term treatment effects with monotone missing data.
The paper proposes an efficient method for estimating ATEs using adaptive experiments.
problem Estimating average treatment effects (ATEs) with minimal sample size and high accuracy.
method The paper defines and uses the efficient treatment-assignment probability to sequentially assign treatments, estimating ATEs using an Adaptive Augmented Inverse Probability Weighting (A2IPW) estimator.
result The proposed experimental design and A2IPW estimator achieve the minimized semiparametric efficiency bound and provide anytime valid confidence intervals for early stopping.
Dynamic covariate balancing: estimating treatment effects over time with potential local projectionsecon.EM
Dynamic treatment effects estimated over time using covariate balancing.
problem Estimating treatment effects in panel data with dynamic treatments.
method Dynamic covariate balancing with potential local projections.
result Established inferential guarantees for the proposed method.
GAMBITTS uses GenAI for adaptive interventions, improving decision-making.
problem Adaptive interventions with GenAI-generated content.
method Generator-mediated bandit-Thompson sampling (GAMBITTS).
result GAMBITTS outperforms standard bandit methods in mobile health interventions.
Selective imputation improves treatment effect estimation from missing data.
problem Missing data complicates treatment effect estimation, especially with treatment variables.
method Introduced mixed confounded missingness (MCM) and selective imputation.
result Selective imputation provides unbiased treatment effect estimates.
The paper develops methods to estimate treatment effects in sample selection models.
problem Evaluation of treatments when outcomes are only observed for a subpopulation due to sample selection or attrition.
method Combines selection-on-observables and instrumental variable assumptions with double machine learning for treatment evaluation.
result Proposed estimators are asymptotically normal and root-n consistent.
Optimal tests developed for sequential experiments with asymptotic properties.
problem Performing hypothesis tests after sequential experiments without prior design.
method Analyze asymptotic properties of sequential experiments; develop tests for Gaussian process observations.
result Asymptotic power function of any test can be matched by a specific test in a limit experiment.
Study designs for estimating treatment effects in adaptive experiments.
problem Estimating treatment effects under adaptive treatment assignment.
method Propose and analyze IPW and AIPW estimators, establish CLTs under design stability.
result Central limit theorems for IPW and AIPW estimators under design stability.
Optimal biomarker combinations for treatment-selection can be derived by minimizing total burden to the population caused by the targeted disease and its treatment. However, when multiple biomarkers are present, including all in the model can be expensive and hurt model performance. To remedy this, we consider feature …
Proposes DSW for unbiased ITE estimation with dynamic confounders.
problem Estimating ITE from dynamic observational data with time-varying confounders.
method Deep Sequential Weighting (DSW) infers hidden confounders using current treatment assignments and historical information.
result DSW generates unbiased and accurate treatment effects.
Generalized Kernel Ridge Regression for Causal Inference with Missing-at-Random Sample Selectionecon.EM
Kernel ridge regression for causal inference with missing data.
problem Estimating treatment effects with missing data in selected samples.
method Kernel ridge regression estimators for nonparametric dose response curves and semiparametric treatment effects.
result Uniform consistency and finite sample rates for continuous treatment, root-n consistency for discrete treatment.
FSRM method improves treatment effect estimation from observational data.
problem Estimating treatment effects from observational data with missing counterfactual outcomes and selection bias.
method FSRM method based on deep representation learning and matching, which maps covariate space into a selective, nonlinear, and balanced representation space.
result FSRM method outperforms state-of-the-art methods in estimating treatment effects.
The paper tackles long-term treatment effects with persistent confounders using sequential short-term outcomes.
problem Estimating long-term treatment effects with persistent unmeasured confounders.
method Exploiting the sequential structure of short-term outcomes, the paper develops three novel identification strategies and corresponding estimators.
result The proposed methods outperform existing approaches in handling persistent confounders.
G-Net uses deep learning for complex counterfactual outcome prediction.
problem Estimating counterfactual outcomes under dynamic treatment strategies.
method G-Net is a sequential deep learning framework for G-computation.
result G-Net can handle complex temporal data and provide accurate treatment effects.
New method selects best HTE estimator without ground-truth treatment effects.
problem Selecting best HTE estimator from multiple candidates.
method Cross-fitted, exponentially weighted test statistic with two-way sample splitting.
result Empirically, reliable error control and reduced false selections.
Method estimates treatment effects with continuous values, correcting for confounding.
problem Estimating treatment effects with continuous values, dealing with confounding.
method Two-stage kernel ridge regression: first stage learns response, second stage corrects for distribution shift.
result Optimal learning bounds achieved without estimating treatment density, adapts to unknown overlap and kernel spectral decay.
Investigates model selection challenges in heterogeneous treatment effect estimation.
problem Lack of validation metrics for choosing the best model in treatment effect estimation.
method Empirical investigation of different model selection criteria.
result Complex interplay between selection strategies, estimators, and data.
New method for estimating counterfactual means in adaptive experiments.
problem Inference for counterfactual means in sequentially designed experiments with adaptive treatment policies.
method Latent factor model and nearest neighbors method for estimation.
result Asymptotically valid confidence intervals for counterfactual means established.
Deep Bayesian models estimate causal effects for dynamic treatment regimes over long follow-up times.
problem Challenges in causal effect estimation for dynamic treatment regimes with long follow-up times.
method Combining outcome regression models with deep Bayesian models for high-dimensional features.
result Stable and accurate dynamic causal effect estimation from observational data, especially with long-term follow-up.
Proposes a new method to find features affecting treatment effect distribution.
problem Existing methods fail to detect differences in treatment effect distribution parameters other than the mean.
method Formulates and estimates a feature importance measure that quantifies feature influence on potential outcome distribution discrepancies. Develops a feature selection algorithm to control type I error rate.
result Successfully discovers important features and outperforms existing mean-based methods.
New method improves reliability of selecting individuals based on predicted treatment effects.
problem Reliability of selecting individuals based on predicted conditional average treatment effects (CATE) is unreliable.
method Denoised Conformal Alignment, combining proxy errors, variance estimation, and Benjamini-Hochberg selection.
result Significantly improved power in selecting individuals while maintaining false discovery rate control.
New method uses online learning to improve AIPW estimators for adaptively collected data.
problem Estimating treatment effects with adaptively collected data.
method Online learning to minimize sequentially weighted estimation error.
result Local minimax lower bound shows optimality of AIPW estimator.
TCFimt forecasts causal effects of multiple interventions from individual data.
problem Estimating causal effects of temporal multi-interventions from individual data.
method TCFimt uses adversarial tasks in seq2seq framework to alleviate bias and contrastive learning to decouple effects.
result TCFimt outperforms state-of-the-art methods in predicting future outcomes and choosing optimal treatments.
Causal Markov Boundariesstat.ML
Paper improves feature selection for predicting outcomes from observational data.
problem Feature selection for post-intervention outcome prediction from pre-intervention variables in healthcare settings.
method Extends Markov boundary concept to treatment-outcome pairs, uses observational and experimental data.
result Combining observational and experimental data improves feature selection and effect estimation.
A new RL framework evaluates dynamic mediation effects over time.
problem Dynamic mediation effects in sequentially assigned treatments.
method Reinforcement Learning framework for decomposition and estimation of causal effects.
result Superior performance demonstrated through numerical studies and real data analysis.
DeepBlip estimates treatment effects over time using neural networks.
problem Estimating treatment effects over time with interpretable blip effects.
method DeepBlip uses a novel double optimization trick to enable simultaneous learning of blip functions with sequential neural networks.
result DeepBlip achieves state-of-the-art performance across various clinical datasets.
Estimates and infers multi-stage stationary treatment policies with variable selection.
problem Valid inference for multi-stage stationary treatment policies with high-dimensional feature variables.
method Estimate the value function using augmented inverse probability weighted estimator, apply penalty for variable selection, construct one-step improvements for valid inference.
result Improved estimators are asymptotically normal, valid inference for policy parameters demonstrated.
We consider a multi-armed bandit problem with covariates. Given a realization of the covariate vector, instead of targeting the treatment with highest conditional expectation, the decision maker targets the treatment which maximizes a general functional of the conditional potential outcome distribution, e.g., a conditi…
This study optimizes covariate density and propensity score for efficient ATE estimation.
problem Efficiently estimating average treatment effects (ATEs) with minimal variance.
method Adaptive experiment optimizing both covariate density and propensity score.
result Proposed method minimizes the semiparametric efficiency bound for ATE estimation.
Are causal effect estimations enough for optimal recommendations under multitreatment scenarios?stat.ML
Enhances credit card limit adjustments by considering treatment uncertainty and prediction criteria.
problem Optimal treatment selection under multitreatment scenarios.
method Proposes a comprehensive methodology incorporating conditional value-at-risk and prediction criterion for continuous outcomes.
result Significantly improved policy performance in credit card limit adjustments.
Method estimates treatment effect bounds in sample selection models.
problem Estimating heterogeneous treatment effects in presence of sample selection.
method Debiased/double machine learning approach for non-linear and high-dimensional confounders.
result Substantially tighter effect bounds for younger users.
The paper shows how expert knowledge can improve treatment effect estimation.
problem Lack of leveraging expert knowledge in treatment effect estimation.
method Formally defining two types of expertise (predictive and prognostic) and demonstrating their influence on treatment effect estimation methods.
result Expertise type significantly influences treatment effect estimation methods, and can be predicted from a dataset.
New method for robust policy evaluation in offline reinforcement learning with sequentially exogenous unobserved confounders.
problem Offline reinforcement learning in domains with unobserved confounders.
method Orthogonalized robust fitted-Q-iteration with closed-form solutions and bias-correction.
result Effective in simulations and real-world data, improving robustness and computational ease.
The paper introduces a new model to correct bias in treatment effect estimates due to sample selection.
problem Bias in treatment effect estimates due to sample selection.
method Type 2 Tobit Bayesian Additive Regression Trees (TOBART-2) with Dirichlet Process Mixture distribution and soft trees.
result Corrects bias in treatment effect estimates by accounting for nonlinearities and model uncertainty.
New method improves treatment effect estimation in adaptive experiments with noncompliance.
problem Estimating average treatment effect in adaptive experiments with binary instrumental variable.
method AMRIV estimator that balances outcome noise and compliance variability.
result AMRIV achieves semiparametric efficiency bound and is robust to noncompliance.
New methods optimize experiment selection for sequential data, improving model accuracy.
problem Optimizing experiment selection for sequential data in multidimensional cases.
method Adopting greedy experiment selection methods for maximum likelihood estimation.
result Proposed methods produce consistent and asymptotically normal estimators.
New framework minimizes interference and selection bias in network A/B testing.
problem Interference and selection bias in network A/B testing.
method Proposes a principled framework that jointly minimizes interference and selection bias using edge spillover probability and cluster matching.
result Significantly lower error in causal effect estimation compared to existing solutions.
We identify and analyze selection structure in sequential data.
problem Selection biases in sequential data can distort analysis and hide underlying generation processes.
method Nonparametric identifiability of selection structure without interventional experiments.
result Selection structure is identifiable in sequential data without parametric assumptions.
Many applied decision-making problems have a dynamic component: The policymaker needs not only to choose whom to treat, but also when to start which treatment. For example, a medical doctor may choose between postponing treatment (watchful waiting) and prescribing one of several available treatments during the many vis…