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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,657 papers · 148 categories

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1223 · Jun 201219922001200920172026
48 results for phylogenetics

Paper proposes learnable topological features for efficient phylogenetic inference.

problem Finding appropriate topological structures for phylogenetic inference tasks requires significant design effort and domain expertise.
method Combines raw node features with graph neural networks to automatically adapt to different tasks.
result Demonstrates effectiveness and efficiency on simulated and real data phylogenetic inference tasks.

Improved phylogenetic inference with normalizing flows.

problem Limitations of current diagonal Lognormal branch length approximation in VBPI.
method Proposes VBPI-NF using normalizing flows to handle non-Euclidean branch length space.
result Significantly improves phylogenetic posterior estimation on real data.

New method embeds phylogenetic trees for clustering, recovering evolutionary relationships.

problem Lack of a meaningful way to embed phylogenetic trees into a vector space.
method Split-weight embedding to fit clustering algorithms to phylogenetic trees.
result Split-weight embedding recovers meaningful evolutionary relationships in simulated and real data.

GeoPhy uses geometric gradients to efficiently infer phylogenetic trees from molecular data.

problem Challenges in accurately inferring species relationships from molecular data due to combinatorially vast tree topologies.
method Introduces a novel, fully differentiable formulation of phylogenetic inference using geometric spaces and variational Bayesian methods.
result Significantly outperforms other approximate Bayesian methods in inferring phylogenetic trees.

A new variational method speeds up Bayesian phylogenetic inference.

problem Slow and inefficient MCMC methods in Bayesian phylogenetic inference.
method Combining subsplit Bayesian networks with variational inference for efficient tree topology and branch length estimation.
result Variational approach provides competitive performance with significantly fewer iterations.

Phylogenetic tree inference using deep DNA sequencing is reshaping our understanding of rapidly evolving systems, such as the within-host battle between viruses and the immune system. Densely sampled phylogenetic trees can contain special features, including "sampled ancestors" in which we sequence a genotype along wit…

2018-05-28abs ↗pdf ↗

We report the results of fifteen sets of portfolio selection simulations using stocks in the ASX200 index for the period May 2000 to December 2013. We investigated five portfolio selection methods, randomly and from within industrial groups, and three based on neighbor-Net phylogenetic networks. We report that using ra…

2016-03-08abs ↗pdf ↗

Improved phylogenetic inference using VBPI-Mixtures for tree topology and branch length.

problem Multimodality of tree-topology posterior distributions in phylogenetic inference.
method VBPI-Mixtures algorithm that uses mixture learning within the BBVI framework.
result VBPI-Mixtures captures tree-topology distributions better than VBPI.

Develops a variational method for ultrametric phylogenetic trees.

problem Accurate and efficient approximation of posterior distributions over trees in Bayesian phylogenetics.
method Variational Bayesian approach based on coalescent times of a single-linkage clustering.
result Achieves competitive accuracy with significantly fewer gradient evaluations.

Paper improves tree probability estimation using stochastic optimization and variance reduction.

problem Improving tree probability estimation in phylogenetic inference.
method Introduces computationally efficient methods for training SBNs and variance reduction for optimization.
result Methods outperform previous baseline methods in tree topology probability estimation and Bayesian phylogenetic inference.

Improved phylogenetic tree reconstruction using flexible branch length distributions.

problem Inefficient Markov chain Monte Carlo methods for large sequence datasets.
method Variational Bayesian phylogenetic inference with semi-implicit branch length distributions.
result Proposed method improves marginal likelihood estimation and branch length posterior approximation.

New method uses hyperbolic space for faster phylogenetic tree inference.

problem Inefficient Euclidean-based phylogenetic inference in high dimensions.
method Developed novel hyperbolic extensions of sequential search algorithms and variational inference methods.
result Improved speed, scalability and performance in phylogenetic inference.

Mathematical foundation for phylogenetic tree uncertainty quantification.

problem Uncertainty in evolutionary relationships between species.
method Introducing the Wald space as a subset of symmetric positive definite matrices, studying its topology and structure, and proposing a new numerical method for geodesics and curvature.
result Wald space has a topology of disjoint open cubes, is contractible, and is a Whitney stratified space of type (A).

Most data in genome-wide phylogenetic analysis (phylogenomics) is essentially multidimensional, posing a major challenge to human comprehension and computational analysis. Also, we can not directly apply statistical learning models in data science to a set of phylogenetic trees since the space of phylogenetic trees is …

2020-03-02abs ↗pdf ↗

Multivariate clustering in astrophysics is a recent development justified by the bigger and bigger surveys of the sky. The phylogenetic approach is probably the most unexpected technique that has appeared for the unsupervised classification of galaxies, stellar populations or globular clusters. On one side, this is a s…

2017-03-01abs ↗pdf ↗

By expressing prior distributions as general stochastic processes, nonparametric Bayesian methods provide a flexible way to incorporate prior knowledge and constrain the latent structure in statistical inference. The Indian buffet process (IBP) is such an example that can be used to define a prior distribution on infin…

2013-07-31abs ↗pdf ↗

Proposes a new phylogenetic tree space with biologically principled geometry.

problem Developing a space for statistical analysis of phylogenies with biologically informed assumptions.
method Introduces wald space, a new phylogenetic tree space, and two related geometries based on Fisher information and Gaussian processes.
result Geodesics in wald space are similar to those in the Fisher information geometry, but the two geometries are distinct.

Latent tree models are graphical models defined on trees, in which only a subset of variables is observed. They were first discussed by Judea Pearl as tree-decomposable distributions to generalise star-decomposable distributions such as the latent class model. Latent tree models, or their submodels, are widely used in:…

2017-08-02abs ↗pdf ↗

Unified framework for inference in complex nonlinear processes.

problem Challenges in inferring nonlinear continuous stochastic processes with sparse observations and complex topologies.
method Neural Backward Filtering Forward Guiding (NBFFG) framework that constructs a variational posterior using a proxy linear-Gaussian process.
result Empirical results show NBFFG outperforms baselines on synthetic benchmarks and high-dimensional phylogenetic analysis tasks.

Develops kernels for matchings, overcoming computational challenges.

problem Challenges in applying kernel methods to matchings due to their discrete, non-Euclidean nature.
method Characterizes stationary kernels, introduces heat and Matérn kernel families, and develops a sub-exponential algorithm for efficient evaluation.
result Establishes novel negative results and identifies an open problem in transferring the framework to trees.

Phylogenetic approaches are finding more and more applications outside the field of biology. Astrophysics is no exception since an overwhelming amount of multivariate data has appeared in the last twenty years or so. In particular, the diversification of galaxies throughout the evolution of the Universe quite naturally…

2016-06-01abs ↗pdf ↗

A toric cube is a subset of the standard cube defined by binomial inequalities. These basic semialgebraic sets are precisely the images of standard cubes under monomial maps. We study toric cubes from the perspective of topological combinatorics. Explicit decompositions as CW-complexes are constructed. Their open cells…

2012-02-20abs ↗pdf ↗

This paper presents a novel application of a clustering algorithm developed for constructing a phylogenetic network to the correlation matrix for 126 stocks listed on the Shanghai A Stock Market. We show that by visualizing the correlation matrix using a Neighbor-Net network and using the circular ordering produced dur…

2015-11-25abs ↗pdf ↗

We study the problem of distinguishing between two distributions on a metric space; i.e., given metric measure spaces (X,d,μ1)({\mathbb X}, d, μ_1) and (X,d,μ2)({\mathbb X}, d, μ_2), we are interested in the problem of determining from finite data whether or not μ1μ_1 is μ2μ_2. The key is to use pairwise distances between observat…

2018-02-04abs ↗pdf ↗

The orientable cover of the moduli space of real genus zero algebraic curves with marked points is a compact aspherical manifold tiled by associahedra, which resolves the singularities of the space of phylogenetic trees. The resolution maps planar metric trees to their underlying abstract representatives, collapsing an…

2010-09-16abs ↗pdf ↗

Scientific investigations that incorporate next generation sequencing involve analyses of high-dimensional data where the need to organize, collate and interpret the outcomes are pressingly important. Currently, data can be collected at the microbiome level leading to the possibility of personalized medicine whereby tr…

2016-07-29abs ↗pdf ↗

We present a technique for clustering categorical data by generating many dissimilarity matrices and averaging over them. We begin by demonstrating our technique on low dimensional categorical data and comparing it to several other techniques that have been proposed. Then we give conditions under which our method shoul…

2015-06-26abs ↗pdf ↗

A Bayesian treatment of latent directed graph structure for non-iid data is provided where each child datum is sampled with a directed conditional dependence on a single unknown parent datum. The latent graph structure is assumed to lie in the family of directed out-tree graphs which leads to efficient Bayesian inferen…

2012-06-13abs ↗pdf ↗

The analysis of Belief Propagation and other algorithms for the {\em reconstruction problem} plays a key role in the analysis of community detection in inference on graphs, phylogenetic reconstruction in bioinformatics, and the cavity method in statistical physics. We prove a conjecture of Evans, Kenyon, Peres, and Sch…

2019-05-24abs ↗pdf ↗

Traditional anatomical analyses captured only a fraction of real phenomic information. Here, we apply deep learning to quantify total phenotypic similarity across 2468 butterfly photographs, covering 38 subspecies from the polymorphic mimicry complex of Heliconius erato\textit{Heliconius erato} and Heliconius melpomene\textit{Heliconius melpomene}. E…

2019-08-15abs ↗pdf ↗

A common assumption in multiple scientific applications is that the distribution of observed data can be modeled by a latent tree graphical model. An important example is phylogenetics, where the tree models the evolutionary lineages of a set of observed organisms. Given a set of independent realizations of the random …

2020-02-28abs ↗pdf ↗