Study uses machine learning to analyze patient survey data for Lyme disease.
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Prediction of disease onset from patient survey and lifestyle data is quickly becoming an important tool for diagnosing a disease before it progresses. In this study, data from the National Health and Nutrition Examination Survey (NHANES) questionnaire is used to predict the onset of type II diabetes. An ensemble model…
The application of existing methods for constructing optimal dynamic treatment regimes is limited to cases where investigators are interested in optimizing a utility function over a fixed period of time (finite horizon). In this manuscript, we develop an inferential procedure based on temporal difference residuals for …
Survey of EEG market and machine learning applications.
Simulation framework assesses ROI of chronic disease adherence and policy timing.
The past decade has seen an explosion in the amount of digital information stored in electronic health records (EHR). While primarily designed for archiving patient clinical information and administrative healthcare tasks, many researchers have found secondary use of these records for various clinical informatics tasks…
This paper tackles data-efficient CEE with scarce labelled data, proposing a method to progressively reduce generalization risk.
Improved forecasting of suicide attempts using LSGPs for patients with little data.
Efficiently fine-tunes patient-independent seizure detection models with tensor kernel machine.
Personalized models explain TB treatment outcomes considering patient context.
Simulates patient pathways to detect delayed rare disease diagnoses.
Model predicts wound and episode-level readmission risk and time to re-admit.
Currently, approximately 30% of epileptic patients treated with antiepileptic drugs (AEDs) remain resistant to treatment (known as refractory patients). This project seeks to understand the underlying similarities in refractory patients vs. other epileptic patients, identify features contributing to drug resistance acr…
Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute coronary syndrome (ACS) is a syndrome due to sudden decrease of coronary artery blood f…
The health outcomes of high-need patients can be substantially influenced by the degree of patient engagement in their own care. The role of care managers includes that of enrolling patients into care programs and keeping them sufficiently engaged in the program, so that patients can attain various goals. The attainmen…
Deep learning model creates patient representations for scalable EHR-based stratification.
Characterizing a patient's progression through stages of sepsis is critical for enabling risk stratification and adaptive, personalized treatment. However, commonly used sepsis diagnostic criteria fail to account for significant underlying heterogeneity, both between patients as well as over time in a single patient. W…
We develop a personalized real time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs. Heterogeneity of the patients population is captured via a hierarchical latent class model. The proposed algorithm aims t…
Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress through disease stages at varying rates. This leads to pathophysiological misalig…
Study automates detection of visitation disruptions in ICU patients.
Bayesian methods improve group testing for identifying infected patients.
To address potential gaps noted in patient monitoring in the hospital, a novel patient behavior detection system using mmWave radar and deep convolution neural network (CNN), which supports the simultaneous recognition of multiple patients' behaviors in real-time, is proposed. In this study, we use an mmWave radar to t…
Model identifies key problems in HIV patients' records.
Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative effectiveness research. One major carrier for conducting patient similarity resea…
Study develops electronic phenotypes of ICU patient acuity.
This paper addresses privacy in federated learning for medical imaging by estimating model uncertainty.
Deep learning clusters patient time-series data for better prognosis.
Multi-output Gaussian processes (GPs) are a flexible Bayesian nonparametric framework that has proven useful in jointly modeling the physiological states of patients in medical time series data. However, capturing the short-term effects of drugs and therapeutic interventions on patient physiological state remains chall…
Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have increased since the millennium change. MIMIC-III, a freely accessible critical care data…
Machine learning detects NASH patients from medical claims data.
Many computational models were proposed to extract temporal patterns from clinical time series for each patient and among patient group for predictive healthcare. However, the common relations among patients (e.g., share the same doctor) were rarely considered. In this paper, we represent patients and clinicians relati…
The paper tracks patient recovery using graphs of joint movement data.
Enhances understanding of patient healthcare journeys using self-attention.
Paper proposes a new method for more accurate group testing of infected patients.
New model identifies patient-specific disease root causes.
Rare diseases affecting 350 million individuals are commonly associated with delay in diagnosis or misdiagnosis. To improve those patients' outcome, rare disease detection is an important task for identifying patients with rare conditions based on longitudinal medical claims. In this paper, we present a deep learning m…
Tens of millions of women suffer from infertility worldwide each year. In vitro fertilization (IVF) is the best choice for many such patients. However, IVF is expensive, time-consuming, and both physically and emotionally demanding. The first question that a patient usually asks before the IVF is how likely she will co…
Deep learning model predicts severe COVID-19 outcomes.
Language models improve clinical prediction models using EHR data.
Adaptive prediction timing improves healthcare outcomes by predicting patient events at the right frequency.
In the scenario of real-time monitoring of hospital patients, high-quality inference of patients' health status using all information available from clinical covariates and lab tests is essential to enable successful medical interventions and improve patient outcomes. Developing a computational framework that can learn…
Improving the quality of end-of-life care for hospitalized patients is a priority for healthcare organizations. Studies have shown that physicians tend to over-estimate prognoses, which in combination with treatment inertia results in a mismatch between patients wishes and actual care at the end of life. We describe a …
Patient notes contain a wealth of information of potentially great interest to medical investigators. However, to protect patients' privacy, Protected Health Information (PHI) must be removed from the patient notes before they can be legally released, a process known as patient note de-identification. The main objectiv…
Machine learning predicts trauma patient mortality risk.
Study predicts risk of true-lumen narrowing after ATAAD surgery using CT data.
VBphenoR uses variational Bayes for EHR-based patient phenotyping.
Generative models create personalized patient health simulations.
Enhances causal estimation using unlabeled offline ICU data.