Parkinson's disease is a neurodegenerative disorder characterized by the presence of different motor impairments. Information from speech, handwriting, and gait signals have been considered to evaluate the neurological state of the patients. On the other hand, user models based on Gaussian mixture models - universal ba…
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48 results for “neurology”
Patients resuscitated from cardiac arrest (CA) face a high risk of neurological disability and death, however pragmatic methods are lacking for accurate and reliable prognostication. The aim of this study was to build computational models to predict post-CA outcome by leveraging high-dimensional patient data available …
Mining discriminative subgraph patterns from graph data has attracted great interest in recent years. It has a wide variety of applications in disease diagnosis, neuroimaging, etc. Most research on subgraph mining focuses on the graph representation alone. However, in many real-world applications, the side information …
Biological and social systems consist of myriad interacting units. The interactions can be represented in the form of a graph or network. Measurements of these graphs can reveal the underlying structure of these interactions, which provides insight into the systems that generated the graphs. Moreover, in applications s…
Neuroimaging modalities such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) provide information about neurological functions in complementary spatiotemporal resolutions; therefore, fusion of these modalities is expected to provide better understanding of brain activity. In this paper, …
Epilepsy is a neurological disorder classified as the second most serious neurological disease known to humanity, after stroke. Localization of the epileptogenic zone is an important step for epileptic patient treatment, which starts with epileptic spike detection. The common practice for spike detection of brain signa…
Structured and sparse partial least squares coherence for multivariate cortico-muscular analysisstat.AP
New algorithm extracts shared latent space for cortico-muscular interactions.
problem Challenges of high dimensionality and limited sample sizes in multivariate cortico-muscular analysis.
method Structured and sparse partial least squares coherence (ssPLSC) algorithm.
result ssPLSC achieves competitive or better performance in scenarios with limited sample sizes and high noise levels.
PR-GNN identifies salient brain regions for ASD biomarkers.
problem Identifying brain regions associated with neurological disorders.
method Pooling Regularized Graph Neural Network (PR-GNN) with novel salient region selection.
result PR-GNN outperforms baseline methods in ASD classification accuracy.
Paper uses TDA for automated Parkinson's disease classification and severity assessment.
problem Manual diagnosis of neurological diseases is time-consuming and inaccurate.
method Combines Topological Data Analysis (TDA) with machine learning on postural shift data.
result Proposes a stable and accurate method for classifying Parkinson's disease.
Paper proposes a new method for population-wise matching of sulcal graphs.
problem Challenges in matching cortical fold variations across individuals.
method Population-wise multi-graph matching of sulcal graphs.
result Effectiveness of multi-graph matching in obtaining consistent labeling of sulcal basins.
Developed a multiway classification method for sparse data.
problem Classification of multiway arrays with sparsity.
method Extended Distance Weighted Discrimination (DWD) to multiway context, accounting for sparsity.
result Improves classification accuracy in multiway structured data.
We first review empirical evidence that asset prices have had episodes of large fluctuations and been inefficient for at least 200 years. We briefly review recent theoretical results as well as the neurological basis of trend following and finally argue that these asset price properties can be attributed to two fundame…
Epilepsy is an important public health issue. An appropriate epileptiform discharge pattern detection of this neurological disease is a typical problem in biomedical engineering. In this paper, a new method is proposed for spike-and-wave discharge pattern detection based on Kendall's Tau-b coefficient. The proposed app…
Sparse GFA identifies disease factors in FTD subgroups.
problem Heterogeneity in neurological disorders hinders understanding and treatment.
method Sparse Group Factor Analysis (GFA) with regularised horseshoe priors.
result Identified latent disease factors differentially expressed in FTD subgroups.
Survey of EEG market and machine learning applications.
problem Improving neurology through data-driven research.
method Comprehensive survey of EEG applications and market.
result Machine learning enhances EEG applications and market growth.
Brain networks have received considerable attention given the critical significance for understanding human brain organization, for investigating neurological disorders and for clinical diagnostic applications. Structural brain network (e.g. DTI) and functional brain network (e.g. fMRI) are the primary networks of inte…
Electroencephalography (EEG) is an extensively-used and well-studied technique in the field of medical diagnostics and treatment for brain disorders, including epilepsy, migraines, and tumors. The analysis and interpretation of EEGs require physicians to have specialized training, which is not common even among most do…
Epilepsy is the most common neurological disorder and an accurate forecast of seizures would help to overcome the patient's uncertainty and helplessness. In this contribution, we present and discuss a novel methodology for the classification of intracranial electroencephalography (iEEG) for seizure prediction. Contrary…
In the big data era, many organizations face the dilemma of data sharing. Regular data sharing is often necessary for human-centered discussion and communication, especially in medical scenarios. However, unprotected data sharing may also lead to data leakage. Inspired by adversarial attack, we propose a method for dat…
WISDoM (Wishart Distributed Matrices) is a new framework for the quantification of deviation of symmetric positive-definite matrices associated to experimental samples, like covariance or correlation matrices, from expected ones governed by the Wishart distribution WISDoM can be applied to tasks of supervised learning,…
Generative model predicts multiple brain graphs from one, preserving topology.
problem Predicting multiple brain graphs from a single one, preserving topology.
method MultiGraphGAN architecture, graph adversarial auto-encoder, cluster-specific decoders, topological loss.
result Significantly outperformed variants in multi-view brain graph generation.
Quantitative susceptibility mapping (QSM) is a powerful MRI technique that has shown great potential in quantifying tissue susceptibility in numerous neurological disorders. However, the intrinsic ill-posed dipole inversion problem greatly affects the accuracy of the susceptibility map. We propose QSMGAN: a 3D deep con…
Weight Friction: A Simple Method to Overcome Catastrophic Forgetting and Enable Continual Learningcs.LG
In recent years, deep neural networks have found success in replicating human-level cognitive skills, yet they suffer from several major obstacles. One significant limitation is the inability to learn new tasks without forgetting previously learned tasks, a shortcoming known as catastrophic forgetting. In this research…
Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to have great efficacy in this domain. These algorithms often use neurological ima…
Drawing an inspiration from behavioral studies of human decision making, we propose here a general parametric framework for a reinforcement learning problem, which extends the standard Q-learning approach to incorporate a two-stream framework of reward processing with biases biologically associated with several neurolo…
Electroencephalography (EEG) during sleep is used by clinicians to evaluate various neurological disorders. In sleep medicine, it is relevant to detect macro-events (> 10s) such as sleep stages, and micro-events (<2s) such as spindles and K-complexes. Annotations of such events require a trained sleep expert, a time co…
Paper characterizes early-stage dementia signatures from sensor data.
problem Detecting early-stage dementia from sensor data.
method Developed bespoke behavioural models from longitudinal sensor data.
result Found subtle differences in sleep quality and wandering between dementia patients and controls.
Deep learning methods are increasingly being used with neuroimaging data like structural and function magnetic resonance imaging (MRI) to predict the diagnosis of neuropsychiatric and neurological disorders. For psychiatric disorders in particular, it is believed that one of the most promising modality is the resting-s…
Knowledge of functional groupings of neurons can shed light on structures of neural circuits and is valuable in many types of neuroimaging studies. However, accurately determining which neurons carry out similar neurological tasks via controlled experiments is both labor-intensive and prohibitively expensive on a large…
Generative adversarial networks (GANs) are recently highly successful in generative applications involving images and start being applied to time series data. Here we describe EEG-GAN as a framework to generate electroencephalographic (EEG) brain signals. We introduce a modification to the improved training of Wasserst…
Maps of brain microarchitecture are important for understanding neurological function and behavior, including alterations caused by chronic conditions such as neurodegenerative disease. Techniques such as knife-edge scanning microscopy (KESM) provide the potential for whole organ imaging at sub-cellular resolution. How…
This work uses Sylvester normalizing flows for more accurate metabolite quantification in MRS.
problem Challenges in accurate metabolite quantification in MRS due to spectral overlap, low SNR, and artifacts.
method Bayesian inference framework with physics-informed Sylvester normalizing flows.
result Accurate metabolite quantification, well-calibrated uncertainties, and insights into parameter correlations and multi-modal distributions.
NeuroQuery synthesizes brain mapping evidence across diverse concepts.
problem Lack of comprehensive meta-analysis of human brain mapping across different mental processes and mechanisms.
method A multivariate model that predicts the spatial distribution of neurological observations given text describing an experiment, cognitive process, or disease.
result Captures relationships and neural correlates of 7,547 neuroscience terms across 13,459 neuroimaging publications.
A new algorithm speeds up EEG source localization using regularization.
problem Challenging inverse problem in mapping EEG readings to brain activity.
method Formulated as a graphical generalized elastic net inverse problem, solved with a variable projected algorithm (VPAL).
result VPAL provides faster and more accurate EEG source localization compared to existing methods.
Advancing fNIRS Neuroimaging through Synthetic Data Generation and Machine Learning Applicationseess.SP
Study generates synthetic fNIRS data and applies machine learning for improved neuroimaging.
problem Scarcity of high-quality fNIRS neuroimaging datasets.
method Synthetic data generation using Monte Carlo simulations and machine learning.
result Improved accuracy and efficiency of fNIRS tomography.
When searching for gene pathways leading to specific disease outcomes, additional information on gene characteristics is often available that may facilitate to differentiate genes related to the disease from irrelevant background when connections involving both types of genes are observed and their relationships to the…
NEURO-DRAM: a 3D recurrent visual attention model for interpretable neuroimaging classificationcs.LG
Deep learning is attracting significant interest in the neuroimaging community as a means to diagnose psychiatric and neurological disorders from structural magnetic resonance images. However, there is a tendency amongst researchers to adopt architectures optimized for traditional computer vision tasks, rather than des…
Tractograms are mathematical representations of the main paths of axons within the white matter of the brain, from diffusion MRI data. Such representations are in the form of polylines, called streamlines, and one streamline approximates the common path of tens of thousands of axons. The analysis of tractograms is a ta…
Localized Sparse Principal Component Analysis of Multivariate Time Series in Frequency Domainstat.ME
The paper introduces a method for interpretable principal component analysis of high-dimensional time series.
problem Inconsistent and difficult-to-interpret principal component estimates in high-dimensional regimes.
method Localized sparse principal component analysis of spectral density matrices in frequency domain.
result Efficient algorithm for sparse-localized estimates of principal subspaces.
Binary and multiclass epilepsy detection methods using EEG features.
problem Epilepsy diagnosis from EEG data.
method Feature extraction from power spectrum, spectrogram, and bispectrogram; eight machine learning algorithms used.
result Random forest and backpropagation algorithms achieved highest accuracy for binary and multiclass classification.
Sparse symmetric tensor regression reduces brain connectivity complexity.
problem Complex brain connectivity analysis in neuroimaging.
method Sparse symmetric tensor regression model for functional connectivity.
result Superior performance in Alzheimer's disease detection.
Unified framework for human-like decision making in various sequential tasks.
problem Real-life decision-making involves diverse strategies leading to similar outcomes.
method Two-stream reward processing mechanism for flexible and unified models.
result Framework unified MAB, CB, and RL with comparable performance.
Electromagnetic stimulation of the human brain is a key tool for the neurophysiological characterization and diagnosis of several neurological disorders. Transcranial magnetic stimulation (TMS) is one procedure that is commonly used clinically. However, personalized TMS requires a pipeline for accurate head model gener…
Brain source imaging is an important method for noninvasively characterizing brain activity using Electroencephalogram (EEG) or Magnetoencephalography (MEG) recordings. Traditional EEG/MEG Source Imaging (ESI) methods usually assume that either source activity at different time points is unrelated, or that similar spat…
Graphical models have gained a lot of attention recently as a tool for learning and representing dependencies among variables in multivariate data. Often, domain scientists are looking specifically for differences among the dependency networks of different conditions or populations (e.g. differences between regulatory …
Deep learning models predict epileptic seizures with high accuracy.
problem Predicting epileptic seizures for better patient care.
method Developed Temporal Multi-Channel Transformer (TMC-T) and Vision Transformer (TMC-ViT) models for EEG signals.
result TMC-ViT model outperformed CNN in seizure prediction.
New framework estimates graph from multimodal functional data.
problem Estimating graph from joint multimodal functional data.
method Integrative framework using partial correlation operator.
result Estimator converges to stationary point with quantifiable error.
After admission to emergency department (ED), patients with critical illnesses are transferred to intensive care unit (ICU) due to unexpected clinical deterioration occurrence. Identifying such unplanned ICU transfers is urgently needed for medical physicians to achieve two-fold goals: improving critical care quality a…