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A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,742 papers · 148 categories

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36811 · Jul 202019922001200920172026
48 results for neurodegenerative disorders

CRBM generates digital twins for MS patients, aiding in disease progression analysis.

problem Characterizing and analyzing disease progression in MS patients.
method Unsupervised machine learning with Conditional Restricted Boltzmann Machines (CRBMs).
result Generated digital twins are statistically indistinguishable from actual subjects.

A method to explain disease transformation using biomarker covariance matrices.

problem Understanding disease transformation from a healthy baseline.
method Modeling healthy and disease states of biomarker covariance matrices to characterize perturbations.
result Disease perturbs the biomarker covariance structure, allowing for mechanistic explanations and individual patient prognosis.

Bayesian approach models neurodegenerative diseases without clinical labels.

problem Personalized, predictive modeling of neurodegenerative diseases.
method Probabilistic programmed deep kernel learning combining Gaussian processes and neural networks.
result Surpasses deep learning in accuracy and timeliness of predicting neurodegeneration.

We introduce Disease Knowledge Transfer (DKT), a novel technique for transferring biomarker information between related neurodegenerative diseases. DKT infers robust multimodal biomarker trajectories in rare neurodegenerative diseases even when only limited, unimodal data is available, by transferring information from …

2019-01-11abs ↗pdf ↗

Proposes a method to cluster fMRI data and estimate brain connectivity networks.

problem Clustering fMRI data to identify patient groups based on brain connectivity.
method Random covariance clustering model (RCCM) to cluster subjects and estimate individual and shared FC networks.
result RCCM outperforms other methods in clustering and FC network estimation, demonstrated through simulations and real data.

Study uses GMM-UBM and i-vectors to assess Parkinson's patients via speech, handwriting, and gait.

problem Assessing neurological state of Parkinson's disease patients using speech, handwriting, and gait signals.
method GMM-UBM and i-vectors applied to speech, handwriting, and gait signals.
result Different feature sets from each signal are crucial for assessing Parkinson's patients.

Study improves LLMs for PPI analysis by addressing uncertainty.

problem Uncertainty in LLM predictions for PPIs.
method Fine-tuned LLaMA-3 and BioMedGPT models, LoRA ensembles, Bayesian LoRA for UQ.
result Competitive PPI identification performance across diverse disease contexts.

Study identifies five AD subtypes using graph diffusion and similarity learning.

problem Identifying homogeneous AD subtypes to improve diagnosis and treatment.
method Unsupervised clustering with graph diffusion and similarity learning.
result Five distinct AD subtypes identified with significant differences in biomarkers and clinical features.

Study uses interviews to automatically detect BD and BPD with good accuracy.

problem Challenges in distinguishing BD and BPD from clinical interviews.
method Developed a multi-modal dataset and used a linear classifier with selected features from interviews.
result Different sets of features characterize BD and BPD, providing insights into their differences.

Study on a pinning model with random walk increments, showing convergence to a critical disordered pinning measure.

problem Understanding the critical behavior of a disordered pinning model.
method Analyzing a disordered pinning model induced by a random walk with specific moment conditions, showing convergence to a limiting measure.
result Convergence of point-to-point partition functions to the critical disordered pinning measure in the critical window.

Automated detection of voice disorders with computational methods is a recent research area in the medical domain since it requires a rigorous endoscopy for the accurate diagnosis. Efficient screening methods are required for the diagnosis of voice disorders so as to provide timely medical facilities in minimal resourc…

2018-12-04abs ↗pdf ↗

As a mental disorder progresses, it may affect brain structure, but brain function expressed in brain dynamics is affected much earlier. Capturing the moment when brain dynamics express the disorder is crucial for early diagnosis. The traditional approach to this problem via training classifiers either proceeds from ha…

2019-11-16abs ↗pdf ↗

The study predicts how discussions in mental disorder Reddit communities affect users' emotional states.

problem Improving mental health conditions through social support analysis.
method Text embedding techniques and RNNs for predicting emotional tone shifts.
result Users' emotional states can improve due to social support, as evidenced by positive comments following negative posts.

New algorithm optimizes matrix reordering for noisy disordered matrices.

problem Optimizing matrix reordering for noisy disordered matrices in single-cell biology and metagenomics.
method Proposed a polynomial-time adaptive sorting algorithm to improve upon spectral seriation.
result Our algorithm achieves superior performance compared to existing methods in real datasets.

The paper generates future brain imaging sequences for Alzheimer's disease detection.

problem Understanding brain aging and neurodegenerative diseases through sequential image data.
method Formulated a min-max problem based on ff-divergence to learn a time series generator using a deep neural network.
result Generated image sequences converge to the latent truth under specific conditions, enhancing downstream tasks like Alzheimer's disease detection.

Deep-learning model detects ASD from MRI data with high accuracy.

problem Challenges in diagnosing ASD due to subjective behavioral assessments and informant biases.
method Integrates deep-learning and SVM techniques to classify ASD brain scans.
result Highly accurate classification of ASD brain scans from neurotypical scans.

Model predicts cannabis use disorder risk for adolescents and young adults.

problem Predicting cannabis use disorder progression in adolescents and young adults.
method Bayesian machine learning model trained on longitudinal data.
result Model provides personalized risk assessment with AUC of 0.68-0.75 and E/O ratio of 0.95-1.

We construct 1-parameter families of non-periodic embedded minimal surfaces of infinite genus in T×RT \times \mathbb{R}, where TT denotes a flat 2-tori. Each of our families converges to a foliation of T×RT \times \mathbb{R} by TT. These surfaces then lift to minimal surfaces in R3\mathbb{R}^3 that are periodic in hori…

2019-08-17abs ↗pdf ↗

Deep learning predicts opioid use disorder risk in patients.

problem Identifying patients at high risk of opioid use disorder.
method Applied LSTM models to analyze electronic health records of opioid users.
result LSTM model outperformed other methods with F1 score of 0.8023 and AUCROC of 0.9369.

This thesis explores emergent intelligence in disordered systems like spin glasses and neural networks.

problem Understanding the principles behind emergent intelligent behaviors in disordered systems.
method Statistical physics approach to charting learning mechanisms and dynamics.
result Uncovering relationships between learning mechanisms and physical dynamics.

Activity and motion analysis has the potential to be used as a diagnostic tool for mental disorders. However, to-date, little work has been performed in turning stratification measures of activity into useful symptom markers. The research presented in this thesis has focused on the identification of objective activity …

2019-08-14abs ↗pdf ↗

We analyze the statistics of daily price change of stock market in the framework of a statistical physics model for the collective fluctuation of stock portfolio. In this model the time series of price changes are coded into the sequences of up and down spins, and the Hamiltonian of the system is expressed by spin-spin…

2001-10-06abs ↗pdf ↗

Deep learning aids in autism diagnosis and rehabilitation using neuroimaging data.

problem Challenges in automated detection and rehabilitation of ASD using neuroimaging data.
method Deep learning techniques applied to neuroimaging data for ASD diagnosis and rehabilitation.
result Deep learning improves accuracy in ASD diagnosis and rehabilitation.

Enhances disease progression modeling using LLMs for complex brain connectivity.

problem Inaccurate predictions of disease spread due to oversimplified brain connectivity models.
method Uses LLMs to synthesize multi-modal relationships and learn disease trajectories from longitudinal data.
result Superior prediction accuracy and interpretability compared to traditional methods.

The analysis of comorbidity is an open and complex research field in the branch of psychiatry, where clinical experience and several studies suggest that the relation among the psychiatric disorders may have etiological and treatment implications. In this paper, we are interested in applying latent feature modeling to …

2014-01-29abs ↗pdf ↗