Study generates synthetic fNIRS data and applies machine learning for improved neuroimaging.
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Study reveals XAI methods fail in neuroimaging, suggesting domain-specific adaptation.
Deep learning aids in autism diagnosis and rehabilitation using neuroimaging data.
InVA models image outcomes from multiple modalities, outperforming standard VAEs.
BPt is a Python library for ML with neuroimaging data.
fastHDMI improves neuroimaging variable selection in high-dimensional data.
Statistical machine learning methods are increasingly used for neuroimaging data analysis. Their main virtue is their ability to model high-dimensional datasets, e.g. multivariate analysis of activation images or resting-state time series. Supervised learning is typically used in decoding or encoding settings to relate…
HBR improves normative modeling of neuroimaging data across multiple sites.
Neuroimaging research has predominantly drawn conclusions based on classical statistics, including null-hypothesis testing, t-tests, and ANOVA. Throughout recent years, statistical learning methods enjoy increasing popularity, including cross-validation, pattern classification, and sparsity-inducing regression. These t…
Deep learning has shown outstanding performance in identifying intricate structures in complex high-dimensional data, especially in the domain of computer vision. The application of deep learning to early detection and automated classification of Alzheimer's disease (AD) has recently gained considerable attention, as r…
Nowadays, a lot of scientific efforts are concentrated on the diagnosis of Alzheimer's Disease (AD) applying deep learning methods to neuroimaging data. Even for 2017, there were published more than a hundred papers dedicated to AD diagnosis, whereas only a few works considered a problem of mild cognitive impairments (…
DeepFDR uses deep learning for better FDR control in neuroimaging data.
The reproducibility of scientific research has become a point of critical concern. We argue that openness and transparency are critical for reproducibility, and we outline an ecosystem for open and transparent science that has emerged within the human neuroimaging community. We discuss the range of open data sharing re…
Traditional voxel-level multiple testing procedures in neuroimaging, mostly -value based, often ignore the spatial correlations among neighboring voxels and thus suffer from substantial loss of power. We extend the local-significance-index based procedure originally developed for the hidden Markov chain models, whic…
Pattern recognition in neuroimaging distinguishes between two types of models: encoding- and decoding models. This distinction is based on the insight that brain state features, that are found to be relevant in an experimental paradigm, carry a different meaning in encoding- than in decoding models. In this paper, we a…
Motivated by applications in neuroimaging analysis, we propose a new regression model, Sparse TensOr REsponse regression (STORE), with a tensor response and a vector predictor. STORE embeds two key sparse structures: element-wise sparsity and low-rankness. It can handle both a non-symmetric and a symmetric tensor respo…
fcHMRF-LIS controls FDR in neuroimaging data, improving power and scalability.
Unified normative modeling for neuroimaging phenotypes using denoising diffusion models.
Deep learning is attracting significant interest in the neuroimaging community as a means to diagnose psychiatric and neurological disorders from structural magnetic resonance images. However, there is a tendency amongst researchers to adopt architectures optimized for traditional computer vision tasks, rather than des…
Novel Bayesian framework for spatio-temporal neuroimaging data.
Deep learning methods have recently made notable advances in the tasks of classification and representation learning. These tasks are important for brain imaging and neuroscience discovery, making the methods attractive for porting to a neuroimager's toolbox. Success of these methods is, in part, explained by the flexi…
This volume is a collection of contributions from the 5th Workshop on Machine Learning and Interpretation in Neuroimaging (MLINI) at the Neural Information Processing Systems (NIPS 2015) conference. Modern multivariate statistical methods developed in the rapidly growing field of machine learning are being increasingly…
A new model for dynamic covariance recovery in neuroimaging data.
This paper describes a new neuroimaging analysis toolbox that allows for the modeling of nonlinear effects at the voxel level, overcoming limitations of methods based on linear models like the GLM. We illustrate its features using a relevant example in which distinct nonlinear trajectories of Alzheimer's disease relate…
Given the wide success of convolutional neural networks (CNNs) applied to natural images, researchers have begun to apply them to neuroimaging data. To date, however, exploration of novel CNN architectures tailored to neuroimaging data has been limited. Several recent works fail to leverage the 3D structure of the brai…
Canonical correlation analysis (CCA) is a valuable method for interpreting cross-covariance across related datasets of different dimensionality. There are many potential applications of CCA to neuroimaging data analysis. For instance, CCA can be used for finding functional similarities across fMRI datasets collected fr…
Novel framework predicts brain biomarker trajectories with superior performance.
A new framework detects statistical significance of deep learning in neuroimaging studies.
Neuroimaging datasets keep growing in size to address increasingly complex medical questions. However, even the largest datasets today alone are too small for training complex machine learning models. A potential solution is to increase sample size by pooling scans from several datasets. In this work, we combine 12,207…
New method handles missing data in multimodal brain imaging.
Pattern recognition methods using neuroimaging data for the diagnosis of Alzheimer's disease have been the subject of extensive research in recent years. In this paper, we use deep learning methods, and in particular sparse autoencoders and 3D convolutional neural networks, to build an algorithm that can predict the di…
Method predicts brain regions for neuroimaging phenotypes.
With the arrival of the big data era, more and more data are becoming readily available in various real-world applications and those data are usually highly heterogeneous. Taking computational medicine as an example, we have both Electronic Health Records (EHR) and medical images for each patient. For complicated disea…
Selective inference improves multi-task neuroimaging analysis.
Bayesian method for estimating functional graphical models from neuroimaging data.
Normative modeling has recently been introduced as a promising approach for modeling variation of neuroimaging measures across individuals in order to derive biomarkers of psychiatric disorders. Current implementations rely on Gaussian process regression, which provides coherent estimates of uncertainty needed for the …
Due to the rapid innovation of technology and the desire to find and employ biomarkers for neurodegenerative disease, high-dimensional data classification problems are routinely encountered in neuroimaging studies. To avoid over-fitting and to explore relationships between disease and potential biomarkers, feature lear…
Efficiently analyzes multidimensional functional data using separable basis functions.
A new geometric framework embeds correlation matrices into Euclidean space for scalable brain network analysis.
Most brain disorders are very heterogeneous in terms of their underlying biology and developing analysis methods to model such heterogeneity is a major challenge. A promising approach is to use probabilistic regression methods to estimate normative models of brain function using (f)MRI data then use these to map variat…
Proposes a new method for analyzing multimodal neuroimaging data.
Machine learning models predict brain age with systematic bias, corrected in this study.
Graph Signal Processing (GSP) is a promising framework to analyze multi-dimensional neuroimaging datasets, while taking into account both the spatial and functional dependencies between brain signals. In the present work, we apply dimensionality reduction techniques based on graph representations of the brain to decode…
Deep learning models brain deformations based on atrophy and growth data.
Multiple hypothesis testing is a significant problem in nearly all neuroimaging studies. In order to correct for this phenomena, we require a reliable estimate of the Family-Wise Error Rate (FWER). The well known Bonferroni correction method, while simple to implement, is quite conservative, and can substantially under…
In the 70s a novel branch of statistics emerged focusing its effort in selecting a function in the pattern recognition problem, which fulfils a definite relationship between the quality of the approximation and its complexity. These data-driven approaches are mainly devoted to problems of estimating dependencies with l…
Framework learns continuous dynamics from sparse trajectories.
Arguably, unsupervised learning plays a crucial role in the majority of algorithms for processing brain imaging. A recently introduced unsupervised approach Deep InfoMax (DIM) is a promising tool for exploring brain structure in a flexible non-linear way. In this paper, we investigate the use of variants of DIM in a se…