A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
ContrastiveVI+ models CRISPR screens with noisy guide efficiency.
New causal models perform poorly when evaluated on biased training sets.
PerturBench benchmarks ML models for cellular perturbation analysis.
BioBO optimizes gene perturbation design using Bayesian optimization with biological priors.
BOBYQA optimizes deep networks with fewer queries than other methods.
Improved genetic programming by optimizing mutation operators for continuous program search.
ENN method uses expectile regression for genetic data analysis of complex diseases.
Semi-supervised GAN creates synthetic genetic data for disease prediction.
Efficiently infers graph edges from genetic similarity data in landscape genetics.
Many complex disease syndromes such as asthma consist of a large number of highly related, rather than independent, clinical phenotypes, raising a new technical challenge in identifying genetic variations associated simultaneously with correlated traits. In this study, we propose a new statistical framework called grap…
Discovering causal genetic variants from large genetic association studies poses many difficult challenges. Assessing which genetic markers are involved in determining trait status is a computationally demanding task, especially in the presence of gene-gene interactions. A non-parametric Bayesian approach in the form o…
Genome-wide association studies (GWAS) have emerged as a rich source of genetic clues into disease biology, and they have revealed strong genetic correlations among many diseases and traits. Some of these genetic correlations may reflect causal relationships. We developed a method to quantify causal relationships betwe…
Novel tests for genetic independence in high-dimensional data.
The application of deep recurrent networks to audio transcription has led to impressive gains in automatic speech recognition (ASR) systems. Many have demonstrated that small adversarial perturbations can fool deep neural networks into incorrectly predicting a specified target with high confidence. Current work on fool…
GROOVE learns representations for weakly paired multimodal data.
Deep models improve GWAS by identifying genetic interactions.
We introduce GeNet, a method for shotgun metagenomic classification from raw DNA sequences that exploits the known hierarchical structure between labels for training. We provide a comparison with state-of-the-art methods Kraken and Centrifuge on datasets obtained from several sequencing technologies, in which dataset s…
Genetic algorithms have been widely used in many practical optimization problems. Inspired by natural selection, operators, including mutation, crossover and selection, provide effective heuristics for search and black-box optimization. However, they have not been shown useful for deep reinforcement learning, possibly …
New method uses DNN for genetic variant identification, controlling randomness and improving interpretability.
Feature selection (FS) has become an indispensable task in dealing with today's highly complex pattern recognition problems with massive number of features. In this study, we propose a new wrapper approach for FS based on binary simultaneous perturbation stochastic approximation (BSPSA). This pseudo-gradient descent st…
Genetic sequence data are well described by hidden Markov models (HMMs) in which latent states correspond to clusters of similar mutation patterns. Theory from statistical genetics suggests that these HMMs are nonhomogeneous (their transition probabilities vary along the chromosome) and have large support for self tran…
Optimizing a neural network's performance is a tedious and time taking process, this iterative process does not have any defined solution which can work for all the problems. Optimization can be roughly categorized into - Architecture and Hyperparameter optimization. Many algorithms have been devised to address this pr…
Paper uses AI to predict stock market volatility with neural networks and genetic algorithms.
In plant and animal breeding studies a distinction is made between the genetic value (additive + epistatic genetic effects) and the breeding value (additive genetic effects) of an individual since it is expected that some of the epistatic genetic effects will be lost due to recombination. In this paper, we argue that t…
A genetic algorithm improves multivariate kernel density estimation.
This paper improves dynamic hedging accuracy using genetic programming to forecast implied volatilities.
For every group genetic code with finite number of generating and at most with one defining relation we introduce the braid group of this genetic code. This construction includes the braid group of Euclidean plane, the braid groups of closed orientable surfaces, B type groups of Artin-Brieskorn, and allow us to study a…
Gradient GA uses gradient information to improve molecular design.
Proposes Genetic Thompson Sampling for multi-armed bandits, improving performance in nonstationary settings.
EvoNUDGE uses graph neural networks to improve genetic programming performance.
As the amount and complexity of genetic information increases it is necessary that we explore some efficient ways of handling these data. This study takes the "divide and conquer" approach for analyzing high dimensional genomic data. Our aims include reducing the dimensionality of the problem that has to be dealt one a…
Genome-wide association studies (GWAS) have achieved great success in the genetic study of Alzheimer's disease (AD). Collaborative imaging genetics studies across different research institutions show the effectiveness of detecting genetic risk factors. However, the high dimensionality of GWAS data poses significant cha…
GEGL uses genetic experts to improve deep learning for molecular design.
Genetic algorithms optimize neural networks for cosmological data analysis.
Technical analysis is used to discover investment opportunities. To test this hypothesis we propose an hybrid system using machine learning techniques together with genetic algorithms. Using technical analysis there are more ways to represent a currency exchange time series than the ones it is possible to test computat…
New method estimates high-dimensional GoM models efficiently.
Gradient boosting enhances existing Mendelian models for genetic disease risk prediction.
Study investigates how preprocessing, feature selection, and model selection affect performance on imbalanced genetic data.
In this paper, we propose a framework for automatic classification of patients from multimodal genetic and brain imaging data by optimally combining them. Additive models with unadapted penalties (such as the classical group lasso penalty or -multiple kernel learning) treat all modalities in the same manner and ca…
Enhances genetic programming for stock alpha discovery with warm start and structural constraints.
Imaging genetic research has essentially focused on discovering unique and co-association effects, but typically ignoring to identify outliers or atypical objects in genetic as well as non-genetics variables. Identifying significant outliers is an essential and challenging issue for imaging genetics and multiple source…
The central aim in this paper is to address variable selection questions in nonlinear and nonparametric regression. Motivated by statistical genetics, where nonlinear interactions are of particular interest, we introduce a novel and interpretable way to summarize the relative importance of predictor variables. Methodol…
Zoetrope Genetic Programming improves symbolic regression performance.
New algorithm reconstructs genealogies from genetic data.
Traditional Linear Genetic Programming (LGP) algorithms are based only on the selection mechanism to guide the search. Genetic operators combine or mutate random portions of the individuals, without knowing if the result will lead to a fitter individual. Probabilistic Model Building Genetic Programming (PMB-GP) methods…
New MCMC method for complex models with large variables.
2 Diabetes is a leading worldwide public health concern, and its increasing prevalence has significant health and economic importance in all nations. The condition is a multifactorial disorder with a complex aetiology. The genetic determinants remain largely elusive, with only a handful of identified candidate genes. G…
We utilize a recently developed genetic algorithm, in conjunction with discrete wavelets, for carrying out successful forecasts of the trend in financial time series, that includes the NASDAQ composite index. Discrete wavelets isolate the local, small scale variations in these non-stationary time series, after which th…