FRESH combines patient-level and aggregate-level data for better clinical decision making.
problem Combining patient-level and aggregate-level data for clinical decision making.
method FRESH method that re-calibrates a patient-level model to match specified aggregate statistics.
result Unified data-efficient model for clinical decision making.
Paper introduces methods to automatically generate SOAP notes from patient-physician conversations.
problem Burden of creating digital SOAP notes by physicians.
method Cluster2Sent algorithm for summarizing patient-physician conversations.
result Cluster2Sent algorithm outperforms existing methods by 8 ROUGE-1 points.
Study re-evaluates MIMIC-III codes, finding many are under-coded.
problem Validity of MIMIC-III clinical codes is questionable.
method Open-source, reproducible methodology for assessing codes.
result Most frequently assigned codes are under-coded up to 35%
ICU readmission is associated with longer hospitalization, mortality and adverse outcomes. An early recognition of ICU re-admission can help prevent patients from worse situation and lower treatment cost. As the abundance of Electronics Health Records (EHR), it is popular to design clinical decision tools with machine …
FedRD improves risk difference estimation in federated learning for clinical outcomes.
problem Privacy-preserving model co-training in medical research is hindered by server-dependent architectures and focus on relative effect measures.
method FedRD is a server-independent, communication-efficient framework for federated risk difference estimation in distributed survival data.
result FedRD provides valid confidence intervals and hypothesis testing, and is asymptotically equivalent to pooled individual-level analysis.
Heart failure hospitalization is a severe burden on healthcare. How to predict and therefore prevent readmission has been a significant challenge in outcomes research. To address this, we propose a deep learning approach to predict readmission from clinical notes. Unlike conventional methods that use structured data fo…
Predicts clinical events using a landmark approach with machine learning for large biomarker histories.
problem Dynamic prediction of clinical events from large biomarker histories.
method Landmark approach extended to endogenous markers history combined with machine learning methods for survival data.
result Superlearner combining regularized regressions and random survival forests outperforms standard survival models.
Model identifies key problems in HIV patients' records.
problem Complex and time-consuming task of identifying patient problems from electronic health records.
method Unsupervised phenotyping approach that jointly learns phenotypes from structured and unstructured data.
result Learned phenotypes and their relatedness are clinically valid and surpass existing methods.
Predicting the risk of mortality for patients with acute myocardial infarction (AMI) using electronic health records (EHRs) data can help identify risky patients who might need more tailored care. In our previous work, we built computational models to predict one-year mortality of patients admitted to an intensive care…
In this work, we present the Grounded Recurrent Neural Network (GRNN), a recurrent neural network architecture for multi-label prediction which explicitly ties labels to specific dimensions of the recurrent hidden state (we call this process "grounding"). The approach is particularly well-suited for extracting large nu…
New method explains survival analysis models using median-SHAP.
problem Need for explainable AI in medical applications, especially for survival analysis.
method Introduces median-SHAP for explaining survival analysis models.
result Conventionally used mean anchor point can lead to misleading interpretations; median-SHAP provides a better approach.
Modeling glucose distribution changes over time using neural ODEs.
problem Analyzing how continuous glucose distribution changes over time in diabetic patients.
method Combines Gaussian mixture, MMD, and Neural ODE to model temporal evolution of glucose distribution.
result Highly interpretable model detects subtle distribution shifts and remains computationally efficient.
New mechanism for pure differential privacy on functional summaries using Laplace-like process.
problem Challenges in achieving differential privacy for complex, structured functional summaries.
method Independent Component Laplace Process (ICLP) mechanism for infinite-dimensional Hilbert space.
result Effective enhancement of utility of private summaries through oversmoothing.
Approximate Bayesian Computation (ABC) methods are used to approximate posterior distributions in models with unknown or computationally intractable likelihoods. Both the accuracy and computational efficiency of ABC depend on the choice of summary statistic, but outside of special cases where the optimal summary statis…
New methods improve brain data analysis from fMRI datasets.
problem Simplified brain models from correlational values are insufficient.
method Deep learning and geometric deep learning techniques.
result Improved predictive spatio-temporal brain data representation.
LIDS assesses LLM summaries with interpretable key words.
problem Challenges in evaluating the quality of LLM summaries.
method BERT-SVD-based direction metric and SOFARI for key word extraction.
result LIDS provides interpretable key words for layered themes.
Unified approach for selecting summary statistics in ABC.
problem Efficient inference from large datasets in likelihood-free methods.
method Characterizing and unifying three classes of summary statistics, minimizing expected posterior entropy.
result EPE-minimizing summaries lead to competitive posterior inference.
Enhances weak lensing inference with neural summaries.
problem Extracting additional information from weak lensing convergence maps.
method Hybrid approach combining physics-based and neural summaries.
result Neural summaries extract up to 8 times more information than angular power spectra.
Approximate Bayesian computation is an established and popular method for likelihood-free inference with applications in many disciplines. The effectiveness of the method depends critically on the availability of well performing summary statistics. Summary statistic selection relies heavily on domain knowledge and care…
Models extract relevant EHR snippets to aid radiologists in diagnosis.
problem Difficulty in identifying relevant patient record information for diagnosis.
method Distantly supervised transformer-based neural model for extractive summarization.
result Models yield better extractive summaries than unsupervised approaches.
Resting-state functional MRI (rs-fMRI) scans hold the potential to serve as a diagnostic or prognostic tool for a wide variety of conditions, such as autism, Alzheimer's disease, and stroke. While a growing number of studies have demonstrated the promise of machine learning algorithms for rs-fMRI based clinical or beha…
Improves inference from sparse data with hybrid summary statistics.
problem Robust simulation-based inference from limited data.
method Augment traditional summary statistics with neural network outputs to maximize mutual information.
result Improves information extraction and makes inference robust in low-data settings.
Automatically learns summary features from time series data for likelihood-free inference.
problem Necessity of hand-tailored summary features for time series data in likelihood-free inference.
method Data-driven approach to automatically learn summary features.
result Learning summary features from data can outperform hand-crafted values in likelihood-free inference.
Text clustering method replaces centroids with summaries for interpretability and scalability.
problem Efficiently clustering text data while maintaining interpretability and scalability.
method k-NLPmeans and k-LLMmeans, which periodically replace numeric centroids with textual summaries.
result Consistently outperforms classical baselines and recent LLM-based clustering methods.
Bayesian neural networks improve with summary information and Dirichlet process.
problem Lack of prior knowledge in BNNs for complex architectures.
method Incorporates external summary information about predicted probabilities using a Dirichlet process.
result Improves model accuracy, uncertainty calibration, and robustness.
Plug-in robust NPE method adapts summaries independently of pretrained NPE.
problem Misspecification of neural posterior estimators under test data distribution.
method Minimum-distance summaries using maximum mean discrepancy (MMD).
result Substantial robustness gains with minimal additional overhead.
Objective: We investigate whether deep learning techniques for natural language processing (NLP) can be used efficiently for patient phenotyping. Patient phenotyping is a classification task for determining whether a patient has a medical condition, and is a crucial part of secondary analysis of healthcare data. We ass…
Few summaries enable automatic summarization of product reviews.
problem Lack of large labeled datasets for training supervised models in opinion summarization.
method Conditional Transformer model trained to generate summaries given other reviews, fine-tuned to predict summary properties.
result Few summaries (5-10) are sufficient to generate fluent, informative, and sentiment-preserving summaries.
Improved likelihood-free inference by localizing and refining low-dimensional approximations.
problem Poor performance of common likelihood-free methods in high-dimensional models.
method Localisation followed by refinement of low-dimensional summaries.
result Improved accuracy in marginal posteriors through localized and refined approximations.
New summary measures reveal geometric structure in weighted measures on manifolds.
problem Lack of geometric information in standard weight-only summaries.
method Heat-kernel entropy profiles, tracking nonuniformity across scales.
result Geometric effective sample size discounts nearby or duplicate particles.
A new method improves likelihood-free Bayesian inference by transforming summary statistics and using efficient Variational Bayes.
problem Incorrectly assuming normally distributed summary statistics in likelihood-free Bayesian inference.
method Wasserstein Gaussianization transformation combined with robust BSL and efficient Variational Bayes.
result Highly efficient and reliable approximate Bayesian inference for likelihood-free problems.
Opinion summarization is the task of automatically creating summaries that reflect subjective information expressed in multiple documents, such as product reviews. While the majority of previous work has focused on the extractive setting, i.e., selecting fragments from input reviews to produce a summary, we let the mod…
Paper uses learned summary statistics for Bayesian inference with difficult likelihood functions.
problem Difficult to obtain exact likelihood function for observation data and simulation model.
method Simulation-based inference with learned summary statistics, using Cressie-Read discrepancy criterion.
result Effective inference performed over selected sample sets of observation data.
Flexible multi-task learning framework using summary statistics.
problem Data-sharing constraints in healthcare settings.
method Proposes a flexible multi-task learning framework utilizing summary statistics and adaptive parameter selection.
result Systematic non-asymptotic analysis and simulations demonstrate the method's performance.
Develops methods to learn centre groupings from summary statistics in multi-centre studies.
problem Violation of homogeneity of parameters across centres in multi-centre studies.
method Clusters-of-Centres (CoC) algorithm that merges centres based on multivariate Cochran-type tests.
result Golden-partition recovery as the number of rounds grows with sample size.
TopoFisher learns topological summaries by maximizing Fisher information, improving parameter efficiency and inference quality.
problem Simulation-based inference misses key information in low-order statistics, especially for non-Gaussian fields.
method TopoFisher uses a differentiable persistent-homology pipeline that learns topological summaries by maximizing local Gaussian Fisher information.
result TopoFisher recovers much of the available information and outperforms fixed topological vectorizations in weak gravitational lensing.
The paper proposes using Autoencoders to learn summary statistics for Bayesian inference.
problem Approximating posterior distributions for models with intractable likelihood functions.
method Using Autoencoders to extract summary statistics that retain parameter information and cancel noise.
result The approach effectively learns summary statistics that improve posterior approximation.
The discovery of clinical biomarkers requires large patient cohorts and is aided by a pooled data approach across institutions. In many countries, data protection constraints, especially in the clinical environment, forbid the exchange of individual-level data between different research institutes, impeding the conduct…
The paper predicts diseases using both clinical and genomics data.
problem Clinical predictions using genomics data are not common.
method Integrated clinical and genomics datasets, machine learning, Principal Component Analysis for feature selection.
result 73% accuracy in predicting 75 disease classes.
Estimates non-parametric logistic model using case-control data and external summary info.
problem Imbalanced binary data in case-control studies.
method Two-step estimation procedure with deep neural network for functional approximation.
result Proposed estimator achieves optimal convergence rate in non-parametric regression.
New clustering method reduces data redundancy for better summaries.
problem Redundancies in data summaries limit their effectiveness in large datasets.
method Khatri-Rao clustering extends centroid-based clustering to produce more succinct summaries.
result Khatri-Rao k-Means and deep clustering frameworks produce more succinct summaries with similar accuracy.
We consider the problem of parametric statistical inference when likelihood computations are prohibitively expensive but sampling from the model is possible. Several so-called likelihood-free methods have been developed to perform inference in the absence of a likelihood function. The popular synthetic likelihood appro…
Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep learning models for the prediction of clinical outcomes using clinical notes. Ho…
Paper introduces a novel framework for set input tasks in meta-learning.
problem Meta-learning problems with set inputs often require efficient summary networks.
method Prototype-oriented optimal transport (POT) framework to improve summary networks.
result Significantly improves summary statistics from sets in meta-learning.
Develops methods for GWAS of high dimensional phenotypes using summary statistics.
problem Lack of methods to model pleiotropy in multi-phenotype GWAS.
method Bayesian inference model using summary statistics, fast computation, and biologically informed priors.
result Demonstrates utility in metabolite GWAS with interpretable pathway-level inference.
The paper tackles robust submodular maximization under matroid constraints, providing approximation algorithms for summary extraction.
problem Maximizing submodular functions while ensuring high value even after deletions.
method Constant-factor approximation algorithms for centralized and streaming settings, considering both non-monotone and monotone objectives.
result Approximation algorithms with space complexity depending on matroid rank and deleted elements, achieving improved factors in monotone cases.
Scaling clustering algorithms to massive data sets is a challenging task. Recently, several successful approaches based on data summarization methods, such as coresets and sketches, were proposed. While these techniques provide provably good and small summaries, they are inherently problem dependent - the practitioner …
Clinical AI models fail to transfer between sites due to site-specific practices.
problem Clinical AI models perform poorly at new sites.
method Identify and isolate site-specific clinical practices affecting data distribution.
result A potential solution to improve model transferability.