We trained and evaluated a localization-based deep CNN for breast cancer screening exam classification on over 200,000 exams (over 1,000,000 images). Our model achieves an AUC of 0.919 in predicting malignancy in patients undergoing breast cancer screening, reducing the error rate of the baseline (Wu et al., 2019a) by …
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48 results for “breast cancer screening”
Deep learning predicts breast cancer with high accuracy from patient data.
problem Early detection of breast cancer from patient data.
method Feature selection and k-fold Monte Carlo cross-validation using deep learning.
result Deep learning model effectively distinguishes between cancer and healthy patients.
Radiologists typically compare a patient's most recent breast cancer screening exam to their previous ones in making informed diagnoses. To reflect this practice, we propose new neural network models that compare pairs of screening mammograms from the same patient. We train and evaluate our proposed models on over 665,…
Breast density classification is an essential part of breast cancer screening. Although a lot of prior work considered this problem as a task for learning algorithms, to our knowledge, all of them used small and not clinically realistic data both for training and evaluation of their models. In this work, we explore the…
We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a cancer in the breast, when tested on the screening population. We attribute the high …
Improved breast cancer screening with a fast, memory-efficient model.
problem Classifying high-resolution breast cancer screening images.
method Extends globally-aware multiple instance classifier to handle image-level labels.
result Achieves AUC of 0.93 in classifying malignant findings, outperforming existing methods.
Study assesses deep neural networks' robustness in mammogram images.
problem Understanding deep neural networks' robustness in mammogram images for breast cancer screening.
method Measuring sensitivity to four perturbations and analyzing low-pass filtering effects.
result Mammogram image classifiers are sensitive to perturbations similar to natural images, but low-pass filtering degrades clinically meaningful features.
High predictive performance and ease of use and interpretability are important requirements for the applicability of a computer-aided diagnosis (CAD) to human reading studies. We propose a CAD system specifically designed to be more comprehensible to the radiologist reviewing screening breast MRI studies. Multiparametr…
Deep learning models designed for visual classification tasks on natural images have become prevalent in medical image analysis. However, medical images differ from typical natural images in many ways, such as significantly higher resolutions and smaller regions of interest. Moreover, both the global structure and loca…
We estimate treatment cost-savings from early cancer diagnosis. For breast, lung, prostate and colorectal cancers and melanoma, which account for more than 50% of new incidences projected in 2017, we combine published cancer treatment cost estimates by stage with incidence rates by stage at diagnosis. We extrapolate to…
Study predicts 10-year survival rates for breast cancer patients.
problem Predicting long-term survival of breast cancer patients.
method Machine learning approaches to assess survival rates.
result Improved accuracy in predicting 10-year survival.
The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer on screening mammograms using an "end-to-end" training approach that efficiently …
Mammography is the most effective and available tool for breast cancer screening. However, the low positive predictive value of breast biopsy resulting from mammogram interpretation leads to approximately 70% unnecessary biopsies with benign outcomes. Data mining algorithms could be used to help physicians in their dec…
Paper identifies key CpG methylation sites for breast cancer.
problem Early detection and treatment of breast cancer.
method Used machine learning on TCGA dataset to classify cancer vs. non-cancer samples.
result Reduced model with 25 key CpG sites achieves over 94% accuracy.
Robust cancer screening model using pre-trained ensembles for biomarkers.
problem Detecting early-stage cancer, especially in hard-to-diagnose cases like pancreatic cancer.
method Meta-trained Hyperfast model for robust classification, combined with ensembling of XGBoost and LightGBM.
result Achieved highest AUC of 0.9929 and robust performance on imbalanced datasets.
Among American women, the rate of breast cancer is only second to lung cancer. An estimated 12.4% women will develop breast cancer over the course of their lifetime. The widespread use of social media across the socio-economic spectrum offers unparalleled ways to facilitate information sharing, in particular as it pert…
Prediction of Malignant & Benign Breast Cancer: A Data Mining Approach in Healthcare Applicationscs.LG
As much as data science is playing a pivotal role everywhere, healthcare also finds it prominent application. Breast Cancer is the top rated type of cancer amongst women; which took away 627,000 lives alone. This high mortality rate due to breast cancer does need attention, for early detection so that prevention can be…
Deep learning model explains breast cancer subtypes using logistic regression.
problem Clarifying the mechanisms of breast cancer subtypes for better treatment.
method Developed a PWL model that generates custom-made logistic regression for each patient.
result The PWL model reveals genes relevant to cell cycle-related pathways.
The paper compares Bayesian trees, Cox models, and random forests for breast cancer survival data.
problem Modeling survival data with nonlinear and additive effects.
method Bayesian Additive Regression Trees, Cox proportional hazards, and Random Survival Forests.
result Bayesian trees outperform other models in terms of bias and prediction accuracy.
Breast cancer is the most frequently reported cancer type among the women around the globe and beyond that it has the second highest female fatality rate among all cancer types. Despite all the progresses made in prevention and early intervention, early prognosis and survival prediction rates are still unsatisfactory. …
Microwave-based breast cancer detection has been proposed as a complementary approach to compensate for some drawbacks of existing breast cancer detection techniques. Among the existing microwave breast cancer detection methods, machine learning-type algorithms have recently become more popular. These focus on detectin…
Radiologist-level Performance by Using Deep Learning for Segmentation of Breast Cancers on MRI Scanscs.LG
Deep learning network matches radiologists in breast cancer segmentation.
problem Automating radiologist-level cancer segmentation from breast MRI.
method 3D U-Net architecture trained on 382,290 breast scans, compared to 255,500 benign cases.
result Network performance matched radiologists' on 2D segmentation of breast cancers.
Paper presents a breast cancer detection model using ELM-RBF.
problem Detecting breast cancer using mammography with high cost and side effects.
method Multilayer fuzzy expert system with ELM-RBF model.
result ELM-RBF model outperforms linear-SVM model in accuracy, precision, sensitivity, specificity, and other metrics.
Unified framework improves gene prioritization in disease studies.
problem Identifying genes involved in diseases using heterogeneous biological data.
method Network propagation-based gene prioritization with integrated biological information.
result Significant improvements in prioritizing genes not identified by traditional methods.
Advances in deep learning for natural images have prompted a surge of interest in applying similar techniques to medical images. The majority of the initial attempts focused on replacing the input of a deep convolutional neural network with a medical image, which does not take into consideration the fundamental differe…
Robust method estimates self-similarity for mammogram images, improving cancer detection.
problem Statistical assessment of self-similarity in real data with large mean level shifts.
method Theil-type weighted regression for wavelet-based estimation, compared to OLS and AV.
result Robust approach shows nearly 68% accuracy in cancer vs non-cancer classification.
An algorithm reduces breast cancer detection data complexity using effect sizes.
problem Improving accuracy in breast cancer detection.
method Statistical feature selection and SVM classifier with linear kernel.
result SVM classifier achieved over 90% accuracy.
DDSTN improves breast cancer diagnosis by leveraging imbalanced ultrasound modalities.
problem Imbalanced ultrasound modalities in diagnosing breast cancer.
method Integrates LUPI and MMD into a deep transfer learning framework.
result Outperforms state-of-the-art algorithms in BUS-based CAD.
Copula-based fusion improves breast cancer risk stratification.
problem Combining clinical and genomic risk scores using simple rules fails to capture their joint relationship.
method Used copulas to model the joint relationship between clinical and genomic risk scores.
result Copula-based fusion improves risk stratification, identifying subgroups with the worst prognosis.
Paper optimizes sparse feature selection for cancer detection using GSVP and SVM.
problem Sparse feature selection for cancer detection.
method Regularized GSVP with proximal gradient descent, feature selection via SVM.
result Near-perfect balanced accuracy with few selected features.
In order to investigate the breast cancer prediction problem on the aging population with the grades of DCIS, we conduct a tree augmented naive Bayesian network experiment trained and tested on a large clinical dataset including consecutive diagnostic mammography examinations, consequent biopsy outcomes and related can…
Deep object detection improves mitotic nucleus detection in breast cancer biopsies.
problem Challenges in automated mitotic nucleus detection in breast cancer histopathological images.
method Adapted Mask R-CNN for deep object detection, initially selects candidate regions with maximum recall, refines them with multi-object loss function.
result Improved discrimination ability (F-score of 0.86) and significant precision (0.86) for mitotic nuclei compared to two-stage models.
Breast cancer is the most common cancer and is the leading cause of cancer death among women worldwide. Detection of breast cancer, while it is still small and confined to the breast, provides the best chance of effective treatment. Computer Aided Detection (CAD) systems that detect cancer from mammograms will help in …
Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation performance of neural network models have been further increased. However, due t…
Breast Cancer Histopathology Image Classification and Localization using Multiple Instance Learningcs.CV
A-MIL improves histopathology image classification and localization.
problem Improving diagnosis of breast cancer through better interpretation of histopathology images.
method Frame image classification as multiple instance learning, use attention-based learning for localization.
result A-MIL achieves better localization without compromising classification accuracy.
PersonalizedUS assesses breast cancer risk with local coverage guarantees.
problem Manual BI-RADS scoring leads to unnecessary biopsies and mental health burden.
method Conformal prediction for precise, personalized risk estimates.
result Local coverage guarantees with high sensitivity and specificity.
In this paper, we analyze the Wisconsin Diagnostic Breast Cancer Data using Machine Learning classification techniques, such as the SVM, Bayesian Logistic Regression (Variational Approximation), and K-Nearest-Neighbors. We describe each model, and compare their performance through different measures. We conclude that S…
Automatization of the diagnosis of any kind of disease is of great importance and it's gaining speed as more and more deep learning solutions are applied to different problems. One of such computer aided systems could be a decision support too able to accurately differentiate between different types of breast cancer hi…
Deep learning predicts response to HER2-targeted breast cancer therapy.
problem Predicting response to HER2-targeted neoadjuvant chemotherapy.
method Developed and validated a deep learning approach using pre-treatment dynamic breast MRI.
result Deep learning model achieved strong performance in predicting pathological complete response.
With an aging and growing population, the number of women requiring either screening or symptomatic mammograms is increasing. To reduce the number of mammograms that need to be read by a radiologist while keeping the diagnostic accuracy the same or better than current clinical practice, we develop Man and Machine Mammo…
The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response. A recent screening of ~1,000 cancer cell lines to a collection of anti-cancer drugs illuminated the link between genotypes and vulnerability. However,…
Neural network improves breast cancer diagnosis with high accuracy.
problem Improving accuracy in breast cancer diagnosis.
method Higher-order probabilistic perceptron (HOPP) model.
result HOPP model achieves up to 97% accuracy in classifying breast cancer tumors.
Method predicts ODX scores for breast cancer patients based on clinical data.
problem Predicting ODX scores for breast cancer patients to aid decision-making.
method Distributional random forest approach using 9 clinico-pathological characteristics.
result Correctly predicted 92% of low risk and 40.2% of high risk patients.
Objectives: Most cancer data sources lack information on metastatic recurrence. Electronic medical records (EMRs) and population-based cancer registries contain complementary information on cancer treatment and outcomes, yet are rarely used synergistically. To enable detection of metastatic breast cancer (MBC), we appl…
Two new feature selection methods improve breast cancer diagnosis accuracy.
problem Improving breast cancer diagnosis accuracy and reducing dataset dimensions.
method Imperialist Competitive Algorithm (ICA) and Bat Algorithm (BA) integrated with ML algorithms.
result BA-based feature selection method outperforms other methods with 99.12% accuracy.
CAT framework improves AI medical screening fairness and reliability.
problem Imbalanced data, varying performance across cohorts, and patient-level inconsistencies in traditional metrics.
method CAT framework introduces patient-level assessment, entropy-based distribution weighting, and cohort-weighted sensitivity and specificity.
result Enhanced predictive reliability, fairness, and interpretability of AI-driven medical screening models.
Sparse Canonical Correlation Analysis (CCA) has received considerable attention in high-dimensional data analysis to study the relationship between two sets of random variables. However, there has been remarkably little theoretical statistical foundation on sparse CCA in high-dimensional settings despite active methodo…
AI detects oral pre-cancerous lesions with high accuracy.
problem Manual screening of oral cavity cancer is expensive and lacks specialists.
method Deep convolutional neural networks (DCNNs) using transfer learning.
result DCNN models achieve high accuracy in distinguishing between benign and pre-cancerous tongue lesions.