MKCapsnet improves schizophrenia identification using multi-kernels and dropout.
problem Identifying schizophrenia using existing methods requires two steps and large amounts of data.
method Developed a multi-kernel capsule network (MKCapsnet) inspired by brain anatomy.
result Outperformed state-of-the-art methods in schizophrenia identification.
Improved Schizophrenia diagnosis using brain signal features with limited observations.
problem Ambulatory diagnoses of neuronal diseases with limited brain signal data.
method Pairwise distance learning approach using Siamese neural network and cosine contrastive loss.
result Improved accuracy and sensitivity in Schizophrenia diagnosis (+10pp).
Kernel and Multiple Kernel Canonical Correlation Analysis (CCA) are employed to classify schizophrenic and healthy patients based on their SNPs, DNA Methylation and fMRI data. Kernel and Multiple Kernel CCA are popular methods for finding nonlinear correlations between high-dimensional datasets. Data was gathered from …
Study finds non-adherence to schizophrenia meds leads to earlier adverse events.
problem Impact of medication non-adherence on adverse outcomes in schizophrenia patients.
method Survival analysis, causal inference methods (T-learner, S-learner, nearest neighbor matching), different amounts of longitudinal information.
result Non-adherence to schizophrenia meds advances adverse events by 1 to 4 months.
Deep CNN classifies EEG-based brain connectivity in schizophrenia.
problem Classifying neuropsychiatric disorders using EEG connectivity.
method Multi-domain connectome CNN framework integrating time and frequency-domain metrics.
result MDC-CNN achieves 93.06% accuracy in schizophrenia classification. Paper presents a method to diagnose schizophrenia using fMRI dynamics from healthy controls.
problem Early diagnosis of mental disorders like schizophrenia using fMRI.
method Self-supervised pre-training on fMRI dynamics of healthy controls for transfer learning.
result Effective classification of schizophrenia using fMRI dynamics with small datasets.
New method captures multimodal disconnectivity in schizophrenia.
problem Misinterpretation of single modality data in schizophrenia research.
method Gaussian graphical model and modularity-based approach on multimodal data.
result Identifies missing links in schizophrenia's default mode network.
Schizophrenia, a mental disorder that is characterized by abnormal social behavior and failure to distinguish one's own thoughts and ideas from reality, has been associated with structural abnormalities in the architecture of functional brain networks. Using various methods from network analysis, we examine the effect …
In this study, we tested the interaction effect of multimodal datasets using a novel method called the kernel method for detecting higher order interactions among biologically relevant mulit-view data. Using a semiparametric method on a reproducing kernel Hilbert space (RKHS), we used a standard mixed-effects linear mo…
Neuroimaging modalities such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) provide information about neurological functions in complementary spatiotemporal resolutions; therefore, fusion of these modalities is expected to provide better understanding of brain activity. In this paper, …
Modeling brain connectivity networks with graph-aware inference.
problem Pooling over functional regions loses information and independence assumptions are unreliable.
method Linear mixed effects model accounting for functional regions and edge dependence.
result Interpretable results comparing schizophrenics and healthy controls.
Simple mean and std-based classifier outperforms chance on 69 out of 128 time-series problems.
problem Time-series classification accuracy comparison
method Linear classifier using mean and standard deviation features
result Simple distributional features outperform chance on 69 out of 128 time-series problems
Improved 3D MRI classification using contrastive learning with continuous proxy metadata.
problem Insufficient labelled data for 3D medical image classification.
method Proposed a new loss function (y-Aware InfoNCE) to leverage continuous proxy metadata in contrastive learning.
result 3D CNN model pre-trained on 10^4 multi-site healthy brain MRI scans outperforms fully-supervised methods.
Proposes a method to cluster fMRI data and estimate brain connectivity networks.
problem Clustering fMRI data to identify patient groups based on brain connectivity.
method Random covariance clustering model (RCCM) to cluster subjects and estimate individual and shared FC networks.
result RCCM outperforms other methods in clustering and FC network estimation, demonstrated through simulations and real data.
Hollow-tree Super resolves feature importance in large datasets.
problem Lack of effective scaling for large feature numbers in boosted tree models.
method Hollow-tree Super (HOTS) methodology for feature importance visualization.
result HOTS effectively resolves feature importance and directionality in high-dimensional neuroscientific data.
A methodology for binary classification of EEG records which correspond to different mental states is proposed. This model-free methodology is based on our theory of the ε-complexity of continuous functions which is extended here (see Appendix) to the case of vector functions. This extension permits us to handle mult…
Approach for recovering shared structure from multiple networks with unknown noise.
problem Recovering shared structure from multiple networks with unknown edge distributions.
method Exploits shared mean structure to denoise edge-level measurements and estimate population-level parameters.
result Established a finite-sample concentration inequality for low-rank eigenvalue truncation of a random weighted adjacency matrix.
We present a method for metric optimization in the Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework, by treating the induced Riemannian metric on the space of diffeomorphisms as a kernel in a machine learning context. For simplicity, we choose the kernel Fischer Linear Discriminant Analysis (KLDA) as th…
DEBIAS learns causal effects from psychiatric longitudinal data by optimizing outcome weights.
problem Causal inference challenges in psychiatric longitudinal data due to symptom heterogeneity and latent confounding.
method DEBIAS algorithm that optimizes outcome weights to maximize durable treatment effects and minimize confounding.
result DEBIAS consistently outperforms state-of-the-art methods in recovering causal effects for clinically interpretable composite outcomes.
LUQ-Learning adapts Q-learning for healthcare decisions considering patient preferences.
problem Optimizing treatment decisions for multivariate outcomes based on individual preferences.
method Latent Utility Q-Learning (LUQ-Learning) framework that adapts Q-learning for composite outcomes.
result LUQ-Learning achieves highly competitive performance compared to alternative methods in simulations.
Deep learning predicts mental disorders from audio and text samples.
problem Predicting mental disorders from speech samples.
method Multimodal deep learning structure using various pre-trained models for audio and text embeddings, transfer learning, and auxiliary corpora.
result Acceptable accuracy in predicting mental disorders through multimodal analysis.
New model extracts shared brain activity patterns from fMRI data.
problem Challenges in aggregating multi-subject fMRI data due to variability.
method Shared Gaussian Process Factor Analysis (S-GPFA) incorporating temporal information.
result Model reveals ground truth latent structures and replicates experimental performance.
Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that seek brain imaging data for specific biomarkers of disorders. These studies hav…
Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned with learning how to make sequences of decisions so as to optimize long-term effect…
Whole MILC learns brain disorder dynamics from unlabeled data.
problem Learning spatio-temporal brain disorder dynamics from unlabeled data.
method Self-supervised pre-training of whole MILC on unlabeled healthy control data.
result Whole MILC outperforms existing methods and provides diagnostic insights.
Clustering is one of the most universal approaches for understanding complex data. A pivotal aspect of clustering analysis is quantitatively comparing clusterings; clustering comparison is the basis for many tasks such as clustering evaluation, consensus clustering, and tracking the temporal evolution of clusters. In p…
Proposes a plastic neural memory model for better anomaly detection.
problem Static attention mechanisms limit NMNs in anomaly detection.
method Introduces dynamic connection weights for improved knowledge retrieval.
result Outperforms state-of-the-art in three medical anomaly detection tasks.
While statistical analysis of a single network has received a lot of attention in recent years, with a focus on social networks, analysis of a sample of networks presents its own challenges which require a different set of analytic tools. Here we study the problem of classification of networks with labeled nodes, motiv…
Locally Linear Embedding improves psychiatric diagnosis accuracy from fMRI data.
problem Improving psychiatric diagnosis accuracy from fMRI data.
method Locally Linear Embedding of BOLD time-series data to optimise feature selection using LOOCV.
result Embedded fMRI gave highly diagnostic performances (> 80%) on eleven publicly-available datasets.
MAGIC uncovers disease heterogeneity across brain scales.
problem Understanding distinct subtypes of brain diseases at different spatial scales.
method Multi-scale Heterogeneity Analysis and Clustering (MAGIC) using semi-supervised clustering.
result Two main subtypes of AD identified with distinct atrophy patterns.
Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are specifically interested in a multivariate approach that uses features derived from …