The analysis of comorbidity is an open and complex research field in the branch of psychiatry, where clinical experience and several studies suggest that the relation among the psychiatric disorders may have etiological and treatment implications. In this paper, we are interested in applying latent feature modeling to …
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48 results for “Psychiatric Disorders”
Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that seek brain imaging data for specific biomarkers of disorders. These studies hav…
Background: Functional magnetic resonance imaging (fMRI) provides non-invasive measures of neuronal activity using an endogenous Blood Oxygenation-Level Dependent (BOLD) contrast. This article introduces a nonlinear dimensionality reduction (Locally Linear Embedding) to extract informative measures of the underlying ne…
Study uses interviews to automatically detect BD and BPD with good accuracy.
problem Challenges in distinguishing BD and BPD from clinical interviews.
method Developed a multi-modal dataset and used a linear classifier with selected features from interviews.
result Different sets of features characterize BD and BPD, providing insights into their differences.
ED-Filter improves eating disorder classification on Twitter.
problem High dimensionality and extensive feature sets in Twitter data for ED classification.
method Informed branch and bound search technique with hybrid greedy-based deep learning.
result Significant improvements in classification accuracy and efficiency.
CI-GNN uses GNNs to diagnose psychiatric disorders by identifying causally relevant brain regions.
problem Leveraging GNNs for psychiatric diagnosis requires interpretable models to understand decision-making.
method CI-GNN integrates Granger causality into GNNs to identify causally relevant subgraphs.
result CI-GNN provides more reliable and concise explanations of psychiatric diagnoses.
Deep learning methods are increasingly being used with neuroimaging data like structural and function magnetic resonance imaging (MRI) to predict the diagnosis of neuropsychiatric and neurological disorders. For psychiatric disorders in particular, it is believed that one of the most promising modality is the resting-s…
Towards automated symptoms assessment in mental healthphysics.med-ph
Activity and motion analysis has the potential to be used as a diagnostic tool for mental disorders. However, to-date, little work has been performed in turning stratification measures of activity into useful symptom markers. The research presented in this thesis has focused on the identification of objective activity …
A new method improves target selection for manipulating complex systems like the brain.
problem Improper incorporation of low-variance outcomes into latent space of predictive models.
method Developed a novel objective based on supervised variational autoencoders (SVAEs) for PPCA (Probabilistic Principal Component Analysis).
result gPCR (Generative Principal Component Regression) dramatically improves target selection in manipulation compared to standard PCR and SVAEs.
Unified framework for human-like decision making in various sequential tasks.
problem Real-life decision-making involves diverse strategies leading to similar outcomes.
method Two-stream reward processing mechanism for flexible and unified models.
result Framework unified MAB, CB, and RL with comparable performance.
ASD-DiagNet: A hybrid learning approach for detection of Autism Spectrum Disorder using fMRI datacs.LG
Mental disorders such as Autism Spectrum Disorders (ASD) are heterogeneous disorders that are notoriously difficult to diagnose, especially in children. The current psychiatric diagnostic process is based purely on the behavioural observation of symptomology (DSM-5/ICD-10) and may be prone to over-prescribing of drugs …
Maturation Trajectories of Cortical Resting-State Networks Depend on the Mediating Frequency Bandq-bio.NC
The functional significance of resting state networks and their abnormal manifestations in psychiatric disorders are firmly established, as is the importance of the cortical rhythms in mediating these networks. Resting state networks are known to undergo substantial reorganization from childhood to adulthood, but wheth…
NEURO-DRAM: a 3D recurrent visual attention model for interpretable neuroimaging classificationcs.LG
Deep learning is attracting significant interest in the neuroimaging community as a means to diagnose psychiatric and neurological disorders from structural magnetic resonance images. However, there is a tendency amongst researchers to adopt architectures optimized for traditional computer vision tasks, rather than des…
Development of interpretable machine learning models for clinical healthcare applications has the potential of changing the way we understand, treat, and ultimately cure, diseases and disorders in many areas of medicine. These models can serve not only as sources of predictions and estimates, but also as discovery tool…
Drawing an inspiration from behavioral studies of human decision making, we propose here a general parametric framework for a reinforcement learning problem, which extends the standard Q-learning approach to incorporate a two-stream framework of reward processing with biases biologically associated with several neurolo…
A framework uses preprocessing to improve psychiatric questionnaire predictions while maintaining interpretability.
problem Weak predictive accuracy and limited interpretability of psychiatric questionnaires.
method Two-stage method: stable preprocessing followed by a linear mapping.
result REFINE outperforms other interpretable approaches in psychiatric and non-psychiatric prediction tasks.
Study finds fMRI can predict suicidal ideation, but analysis questions results.
problem Predicting suicidal ideation using fMRI data.
method Naive Bayes classifier trained on fMRI responses to words related to mortality.
result Classification accuracy of 91% for predicting suicidal ideation, but analysis calls into question the accuracy of the findings.
Paper proposes a new method for population-wise matching of sulcal graphs.
problem Challenges in matching cortical fold variations across individuals.
method Population-wise multi-graph matching of sulcal graphs.
result Effectiveness of multi-graph matching in obtaining consistent labeling of sulcal basins.
DEBIAS learns causal effects from psychiatric longitudinal data by optimizing outcome weights.
problem Causal inference challenges in psychiatric longitudinal data due to symptom heterogeneity and latent confounding.
method DEBIAS algorithm that optimizes outcome weights to maximize durable treatment effects and minimize confounding.
result DEBIAS consistently outperforms state-of-the-art methods in recovering causal effects for clinically interpretable composite outcomes.
Over the last twenty five years, advances in the collection and analysis of fMRI data have enabled new insights into the brain basis of human health and disease. Individual behavioral variation can now be visualized at a neural level as patterns of connectivity among brain regions. Functional brain imaging is enhancing…
Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are specifically interested in a multivariate approach that uses features derived from …
Method for understanding heterogeneous treatment effects in complex causal graphs.
problem Heterogeneity and comorbidity in healthcare problems.
method Developed a new approach to characterize heterogeneous causal effects (HCEs) in graphical contexts, including heterogeneous causal graphs (HCGs) with confounders and mediators.
result Established theoretical forms and properties of HCEs in linear and nonlinear models, and developed interactive structural learning for estimation.
Neural Processes Mixed-Effect Models for Deep Normative Modeling of Clinical Neuroimaging Datastat.ML
Normative modeling has recently been introduced as a promising approach for modeling variation of neuroimaging measures across individuals in order to derive biomarkers of psychiatric disorders. Current implementations rely on Gaussian process regression, which provides coherent estimates of uncertainty needed for the …
New robust method for high-dimensional data analysis in imaging studies.
problem Analyzing high-dimensional data with complex dependence and outliers.
method Robust high-dimensional regression with coefficient thresholding and Huber loss.
result Statistical consistency and computational convergence under high-dimensional settings.
A signature-based machine learning model for bipolar disorder and borderline personality disorderstat.ML
Mobile technologies offer opportunities for higher resolution monitoring of health conditions. This opportunity seems of particular promise in psychiatry where diagnoses often rely on retrospective and subjective recall of mood states. However, getting actionable information from these rather complex time series is cha…
Study on a pinning model with random walk increments, showing convergence to a critical disordered pinning measure.
problem Understanding the critical behavior of a disordered pinning model.
method Analyzing a disordered pinning model induced by a random walk with specific moment conditions, showing convergence to a limiting measure.
result Convergence of point-to-point partition functions to the critical disordered pinning measure in the critical window.
Proposes a method to cluster fMRI data and estimate brain connectivity networks.
problem Clustering fMRI data to identify patient groups based on brain connectivity.
method Random covariance clustering model (RCCM) to cluster subjects and estimate individual and shared FC networks.
result RCCM outperforms other methods in clustering and FC network estimation, demonstrated through simulations and real data.
Glottal Closure Instants Detection From Pathological Acoustic Speech Signal Using Deep Learningcs.SD
In this paper, we propose a classification based glottal closure instants (GCI) detection from pathological acoustic speech signal, which finds many applications in vocal disorder analysis. Till date, GCI for pathological disorder is extracted from laryngeal (glottal source) signal recorded from Electroglottograph, a d…
Automated detection of voice disorders with computational methods is a recent research area in the medical domain since it requires a rigorous endoscopy for the accurate diagnosis. Efficient screening methods are required for the diagnosis of voice disorders so as to provide timely medical facilities in minimal resourc…
As a mental disorder progresses, it may affect brain structure, but brain function expressed in brain dynamics is affected much earlier. Capturing the moment when brain dynamics express the disorder is crucial for early diagnosis. The traditional approach to this problem via training classifiers either proceeds from ha…
Whole MILC learns brain disorder dynamics from unlabeled data.
problem Learning spatio-temporal brain disorder dynamics from unlabeled data.
method Self-supervised pre-training of whole MILC on unlabeled healthy control data.
result Whole MILC outperforms existing methods and provides diagnostic insights.
The study predicts how discussions in mental disorder Reddit communities affect users' emotional states.
problem Improving mental health conditions through social support analysis.
method Text embedding techniques and RNNs for predicting emotional tone shifts.
result Users' emotional states can improve due to social support, as evidenced by positive comments following negative posts.
The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in the epidemic. Individuals who are prescribed opioids, and who are diagnosed wit…
Matrix Reordering for Noisy Disordered Matrices: Optimality and Computationally Efficient Algorithmsmath.ST
New algorithm optimizes matrix reordering for noisy disordered matrices.
problem Optimizing matrix reordering for noisy disordered matrices in single-cell biology and metagenomics.
method Proposed a polynomial-time adaptive sorting algorithm to improve upon spectral seriation.
result Our algorithm achieves superior performance compared to existing methods in real datasets.
Vocal disorders have affected several patients all over the world. Due to the inherent difficulty of diagnosing vocal disorders without sophisticated equipment and trained personnel, a number of patients remain undiagnosed. To alleviate the monetary cost of diagnosis, there has been a recent growth in the use of data a…
A new method clusters subjects based on brain networks without vectorizing fMRI data.
problem Distortion of clustering results when simplifying fMRI data structure.
method Wishart mixture models for multiple-view clustering of brain networks.
result Identifies multiple underlying pairs of associations between subject clusters and brain sub-networks.
Deep-learning model detects ASD from MRI data with high accuracy.
problem Challenges in diagnosing ASD due to subjective behavioral assessments and informant biases.
method Integrates deep-learning and SVM techniques to classify ASD brain scans.
result Highly accurate classification of ASD brain scans from neurotypical scans.
Model predicts cannabis use disorder risk for adolescents and young adults.
problem Predicting cannabis use disorder progression in adolescents and young adults.
method Bayesian machine learning model trained on longitudinal data.
result Model provides personalized risk assessment with AUC of 0.68-0.75 and E/O ratio of 0.95-1.
We construct 1-parameter families of non-periodic embedded minimal surfaces of infinite genus in , where denotes a flat 2-tori. Each of our families converges to a foliation of by . These surfaces then lift to minimal surfaces in that are periodic in hori…
Investigates stochastic networks on disordered lattices, converging to Brownian web in 2D.
problem Stochastic networks on disordered lattices.
method Directed spanning forests on randomly perturbed lattices.
result DSF converges to Brownian web in 2D under diffusive scaling.
Key features of mental illnesses are reflected in speech. Our research focuses on designing a multimodal deep learning structure that automatically extracts salient features from recorded speech samples for predicting various mental disorders including depression, bipolar, and schizophrenia. We adopt a variety of pre-t…
Identifying Risk of Opioid Use Disorder for Patients Taking Opioid Medications with Deep Learningcs.LG
Deep learning predicts opioid use disorder risk in patients.
problem Identifying patients at high risk of opioid use disorder.
method Applied LSTM models to analyze electronic health records of opioid users.
result LSTM model outperformed other methods with F1 score of 0.8023 and AUCROC of 0.9369.
This thesis explores emergent intelligence in disordered systems like spin glasses and neural networks.
problem Understanding the principles behind emergent intelligent behaviors in disordered systems.
method Statistical physics approach to charting learning mechanisms and dynamics.
result Uncovering relationships between learning mechanisms and physical dynamics.
This thesis evaluates text-based vs audio-based classification of mental health interviews.
problem Classifying psychiatric illness using text-based methods.
method Design and evaluate a text classification network on mental health interviews, using belabBERT.
result Text-based classification is a strong alternative to audio-based methods.
Transfer entropy shows abnormal brain connectivity in depression.
problem Abnormal brain connectivity in depression.
method Transfer entropy analysis on EEG recordings.
result Aberrated dynamics and direction of information between brain centers in depression.
Entropy and Economicsq-fin.GN
Entropy helps explain disorder in both macro and micro systems.
problem Connecting macro and micro systems with entropy analysis.
method Analyzing entropy from both macroscopic and microscopic perspectives.
result Entropy measures disorder in both macroscopic and microscopic systems.
Machine learning improves ASD diagnosis accuracy.
problem Early detection and treatment of ASD.
method Machine learning, specifically SMO-SVM and Relief Attributes.
result SMO-SVM classifier outperforms other algorithms in ASD detection.
PR-GNN identifies salient brain regions for ASD biomarkers.
problem Identifying brain regions associated with neurological disorders.
method Pooling Regularized Graph Neural Network (PR-GNN) with novel salient region selection.
result PR-GNN outperforms baseline methods in ASD classification accuracy.