MATCH-Net uses CNNs to predict disease trajectories accurately.
problem Inaccurate prediction of disease trajectories in survival analysis.
method Developed a Missingness-Aware Temporal Convolutional Hitting-time Network (MATCH-Net).
result Demonstrated state-of-the-art performance in real-world Alzheimer's data.
Survival analysis in the presence of multiple possible adverse events, i.e., competing risks, is a pervasive problem in many industries (healthcare, finance, etc.). Since only one event is typically observed, the incidence of an event of interest is often obscured by other related competing events. This nonidentifiabil…
The paper proposes a method to estimate heterogeneous treatment effects using pretraining strategies.
problem Estimating conditional average treatment effects (CATE) in the presence of many covariates.
method The approach leverages prognostic factors that also predict treatment effect heterogeneity, using the R-learner framework.
result The proposed method improves estimation accuracy and power for detecting treatment effect heterogeneity.
Deep learning models predict postoperative complications more accurately than random forests.
problem Predicting postoperative complications to inform patient care decisions.
method Multi-task deep neural networks integrating intraoperative physiological data.
result Deep learning models improved prediction accuracy and provided interpretable risk factors.
Study uses LLMs to create personalized treatment plans for rare gynecological tumors.
problem Suboptimal management and poor prognosis due to low incidence and heterogeneity of rare gynecological tumors.
method Developed a digital twin system using LLMs to integrate clinical and biomarker data.
result LLM-enabled digital twins efficiently model individual patient trajectories and identify potential treatment options.
Deep Learning predicts prognosis of AML cases using cytogenetics, age, and mutations.
problem Predicting prognosis of acute myeloid leukemia (AML) cases.
method Hierarchical Deep Learning model using autoencoders, trained on TCGA database.
result Achieved 83% accuracy in predicting prognosis of AML cases.
Bayesian model learns cancer subtypes from diverse NGS data.
problem Overdispersed NGS count data and limited samples for specific cancer types.
method Bayesian Multi-Domain Learning (BMDL) model using hierarchical negative binomial factorization.
result BMDL achieves reproducible cancer subtyping without negative transfer effects.
A data-driven approach predicts morphological development under structural instability.
problem Understanding and predicting spatiotemporal complexities of morphogenesis under structural instability.
method Machine-learning framework based on physical modeling of morphogenesis.
result Identification of key bifurcation characteristics and prediction of history-dependent development.
Robo-advisor improves investment advice through client interaction.
problem Offering personalized financial advice to clients.
method Adaptive mean-variance portfolio optimization with client interaction.
result Optimal investment strategy includes both myopic and intertemporal hedging terms.
New model identifies cell-specific genes for cancer prognosis.
problem No statistical model to integrate multiscale cancer data.
method Bayesian generalized promotion time cure models (GPTCMs).
result Improves cancer prognosis by identifying cell-specific genes.
IRL models human risk decisions based on past outcomes.
problem Understanding human risk decisions under risk.
method Inverse Reinforcement Learning (IRL) with features reflecting state history.
result Human reward function explains risk-prone and risk-averse decisions.
AI models assess psychological risks in currency trading.
problem Identifying psychological risks in currency traders.
method Developed a decision tree model to identify patterns in historical data.
result Enhanced decision-making through real-time alerts.
Consider a platform that wants to learn a personalized policy for each user, but the platform faces the risk of a user abandoning the platform if she is dissatisfied with the actions of the platform. For example, a platform is interested in personalizing the number of newsletters it sends, but faces the risk that the u…
DeFi doesn't fully remove trust, showing run risk and personal character's importance.
problem The need for trust in DeFi despite its code-based approach.
method Natural experiment revealing identities of DeFi participants, including a criminal.
result DeFi doesn't fully remove trust, showing run risk and personal character's relevance.
HACSurv models dependencies between competing risks and censoring for improved survival analysis.
problem Inaccurate survival predictions due to ignoring dependencies between competing risks and censoring.
method HACSurv uses hierarchical Archimedean copulas to model dependencies and cause-specific survival functions.
result HACSurv improves accuracy in survival predictions and captures complex risk interactions.
Machine learning improves glioma diagnosis and prognosis.
problem Improving glioma diagnosis and prognosis using imaging biomarkers.
method Search PubMed and MEDLINE for articles applying machine learning to high-grade glioma biomarkers.
result Machine learning enables accurate classification of glioma biomarkers.
We develop a personalized real time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs. Heterogeneity of the patients population is captured via a hierarchical latent class model. The proposed algorithm aims t…
Network Elastic Net identifies smoking-specific gene expression for lung cancer prognosis.
problem Identifying smoking-specific gene expression biomarkers in lung cancer prognosis.
method Introduces Network Elastic Net, a method that clusters and regresses on graphs based on smoking behavior.
result Shows efficacy of clusters in identifying cancer stages using gene expression and smoking behavior.
Quantitative CT predicts ILD patterns and prognosis.
problem Diagnosing and predicting prognosis of fibrosing ILD patterns.
method High-resolution CT texture features, TM model for classification and survival analysis.
result TM model outperforms histogram-based model in distinguishing UIP from non-UIP patterns and allows for survival group partitioning.
New algorithm assesses credit risk in multilayer networks over time.
problem Quantifying evolving credit risk in complex, interconnected networks.
method Personalized PageRank algorithm for multilayer networks.
result Credit risk evolves and propagates through multilayer networks over time.
Kernel method optimizes personalized dose rules for patients.
problem Finding optimal individualized dose rules for patients.
method Kernel assisted learning method for estimating optimal dose rules.
result The method identifies the optimal individualized dose rule and produces favorable outcomes.
Predicts academic risk in college students using interpretable machine learning.
problem Predicting academic risk from high-dimensional, unbalanced student data.
method Binary classification task using LightGBM model and Shapley value.
result 8 predictors for academic risk identified, including quality of academic partners and dormitory study atmosphere.
Personalized models using group attributes reduce performance, study finds.
problem Reducing performance of models using group attributes like race or gender.
method Formal conditions and collective preference guarantees to ensure fair use.
result Models personalized with group attributes reduce performance at a group level.
We study the effects of non-systematic and systematic mortality risks on the required initial capital in a pension plan, in the presence of financial risks. We discover that for a pension plan with few members the impact of pooling on the required capital per person is strong, but non-systematic risk diminishes rapidly…
Deep learning predicts lung cancer prognosis by controlling collider effects.
problem Unbiased survival predictions for lung cancer patients.
method Dual task network predicting both outcome and collider, enforcing independence with OLS.
result Unbiased individual prognosis predictions are possible with deep learning.
Paper analyzes minimax risks of personalized federated learning algorithms.
problem Statistical heterogeneity among clients in federated learning.
method Minimax analysis of FedAvg and local training approaches.
result Threshold for optimality between FedAvg and local training depends on data heterogeneity.
Early diagnosis is important for type 2 diabetes (T2D) to improve patient prognosis, prevent complications and reduce long-term treatment costs. We present a novel risk profiling approach based exclusively on health expenditure data that is available to Belgian mutual health insurers. We used expenditure data related t…
CovidCare uses EMR data to predict patient outcomes in emerging epidemics.
problem Intelligent prognosis for patients with emerging infectious diseases during rapid epidemics.
method Transfer learning and knowledge distillation from existing EMR data.
result CovidCare outperforms baseline methods in predicting patient length of stay.
A new DP algorithm for weighted ERM protects sensitive data in predictive models.
problem Protecting sensitive personal information in predictive models trained via ERM.
method Proposes the first differentially private algorithm for weighted ERM with formal privacy guarantees.
result Demonstrates strong DP guarantees while maintaining robust performance in real-world data.
Deep learning predicts patient trajectories in open Mimic-III dataset.
problem Predicting future medical conditions from patient history.
method Two parallel bi-directional Minimal Gated Recurrent Unit networks trained on Mimic-III dataset.
result Significant improvements in automated medical prognosis measured by Recall@k.
The paper estimates personalized treatment effects in medical settings with competing risks.
problem Estimating treatment effectiveness for specific events in the presence of alternative event types.
method Meta-learners combining Cox regression or random survival forests for risk modeling and elastic net regression or random forests for direct CATE modeling.
result Compared meta-learners in multiple simulation settings, providing practical guidance for model selection.
Copula-based fusion improves breast cancer risk stratification.
problem Combining clinical and genomic risk scores using simple rules fails to capture their joint relationship.
method Used copulas to model the joint relationship between clinical and genomic risk scores.
result Copula-based fusion improves risk stratification, identifying subgroups with the worst prognosis.
The process of contagiousness spread modelling is well-known in epidemiology. However, the application of spread modelling to banking market is quite recent. In this work, we present a system of ordinary differential equations, simulating data from the largest European banks. Then, an optimal control problem is formula…
Study predicts risk of true-lumen narrowing after ATAAD surgery using CT data.
problem Early post-surgery risk assessment for aortic dissection patients.
method Retrospective study with CT data, derived cross-sectional shapes, form factor (FF) for morphology assessment, linear discriminant analysis (LDA) for risk classification, LOPO-CV for prediction.
result Machine-learning model accurately predicts risk for all high-risk patients and low-risk patients, potentially reducing hospital visits.
A coin-flipping game paradox illustrates how conditional probability estimation can distort risk assessment.
problem Distortion of risk assessment due to incorrect conditional probability estimation.
method A coin-flipping game to illustrate the paradox of conditional probability estimation.
result Incorrect conditional probability estimation can lead to excessive risk bearing.
LLMs can simulate human investment attitudes based on personality traits.
problem Investigating how LLMs mimic human investment behaviors.
method Simulated investment task using LLM personas with specific Big Five personality profiles.
result LLMs can produce meaningful behavioural differences in investment tasks that align with human traits.
This study maps cycling risks and discomfort in Zurich, offering personalized route recommendations.
problem High cycling accidents and discomfort in Smart Cities.
method Geolocated bike accidents data, kernel density contours, weather, time, accident type and severity analysis.
result Empirical continuous spatial risk estimations and personalized route recommendations.
A new algorithm improves top-k recommendation accuracy by considering item payoffs uncertainty.
problem Suboptimal performance in top-k recommendation rankings due to varying item payoffs. method Proposes a risk-seeking utility function for ranking items based on estimated preference scores.
result Risk-seeking ranking yields the best performance in top-k recommendations. The personalization of treatment via bio-markers and other risk categories has drawn increasing interest among clinical scientists. Personalized treatment strategies can be learned using data from clinical trials, but such trials are very costly to run. This paper explores the use of active learning techniques to desig…
Study tackles contamination and heterogeneity in multi-task learning, improving robustness and personalization.
problem Challenges in integrating related tasks due to contamination and heterogeneity.
method Proposes a filtering-based robust multi-task gradient descent method to estimate global and clean task-specific minimizers.
result Demonstrates improved robustness and personalization compared to existing methods.
AI-enabled precision medicine promises a transformational improvement in healthcare outcomes by enabling data-driven personalized diagnosis, prognosis, and treatment. However, the well-known "curse of dimensionality" and the clustered structure of biomedical data together interact to present a joint challenge in the hi…
Risk-stratify improves risk stratification for cardiovascular disease.
problem Accurately stratify patients for cardiovascular disease prognosis.
method Two-phase algorithm: tree partitioning followed by graph decomposition.
result Significant reduction in false discovery rate (33%) compared to state-of-the-art methods.
Study of recurrences in earthquakes, climate, financial time-series, etc. is crucial to better forecast disasters and limit their consequences. However, almost all the previous phenomenological studies involved only a long-ranged autocorrelation function, or disregarded the multi-scaling properties induced by potential…
Deep ROC analysis improves model selection and interpretation in medical and AI applications.
problem Inadequate performance measures for binary classifiers.
method Deep ROC analysis, translating AUC and partial AUC into balanced average accuracy and post-test measures.
result Deep ROC analysis provides balanced average accuracy, average sensitivity, and average specificity.
SAFER improves personalized treatment recommendations for dynamic clinical contexts.
problem Personalized treatment optimization in evolving clinical contexts with safety concerns.
method Integrates structured EHR and clinical notes, uses conformal prediction for safe recommendations.
result SAFER outperforms state-of-the-art baselines in recommendation metrics and mortality rates.
ML system reduces overdraft fees for Mint users.
problem Overdraft fees burden Americans, leading to financial hardship.
method ML-driven overdraft early warning system (ODEWS).
result Saved $3 million in overdraft fees for Mint customers.
Model predicts cannabis use disorder risk for adolescents and young adults.
problem Predicting cannabis use disorder progression in adolescents and young adults.
method Bayesian machine learning model trained on longitudinal data.
result Model provides personalized risk assessment with AUC of 0.68-0.75 and E/O ratio of 0.95-1.
Study shows LLM-advisors match human performance in eliciting preferences but struggle with conflicting needs and trust.
problem How do LLM-advisors perform in complex financial domains where domain expertise is crucial?
method Lab-based user study with 64 participants, focusing on three challenges: preference elicitation, personalized guidance, and relationship building.
result LLM-advisors can match human performance in preference elicitation but struggle with conflicting needs and trust issues.