The study examines machine learning classification algorithms and their generalizability using Framingham Heart Study data.
problem Addressing biases and generalizability issues in machine learning classification algorithms.
method Comparison of eight machine learning classification algorithms on Framingham Heart Study data.
result Double discriminant scoring of type I is the most generalizable algorithm.
Missing data is a common problem in real-world settings and particularly relevant in healthcare applications where researchers use Electronic Health Records (EHR) and results of observational studies to apply analytics methods. This issue becomes even more prominent for longitudinal data sets, where multiple instances …
The electronic health record (EHR) provides an unprecedented opportunity to build actionable tools to support physicians at the point of care. In this paper, we investigate survival analysis in the context of EHR data. We introduce deep survival analysis, a hierarchical generative approach to survival analysis. It depa…
BoXHED boosts hazard estimation for dynamic health risk scores.
problem Analyzing time-varying health vitals for disease onset prediction.
method Gradient boosting for nonparametric hazard function estimation with time-dependent covariates.
result Novel interaction effects among risk factors identified in cardiovascular disease onset data.
Develops a novel approach for estimating optimal DTRs with multicategory treatments and censored data.
problem Estimating optimal treatment regimes for chronic diseases with censored data.
method Angle-based multicategory classification algorithm for maximizing conditional survival function.
result The proposed method outperforms existing approaches in maximizing conditional survival function.
New method stabilizes deep learning models for clinical risk prediction.
problem Stability issues in deep learning models for clinical risk prediction.
method Bootstrapping-based regularisation framework embedded in deep neural networks.
result Improved prediction stability across multiple datasets.
Framework for imputing missing heart data to simulate brain-heart interactions.
problem Lack of multi-modal patient data representing heart and brain processes.
method Probabilistic framework for joint cardiac data imputation and mechanistic model personalization.
result Accurate imputation of missing cardiac features in incomplete datasets.
Smartphones can estimate heart rate from other sensor data.
problem Gaps in heart rate data from wearable sensors.
method Regression, SVM, and random forest algorithms to estimate heart rate from smartphone data.
result Smartphone data can improve heart rate estimation from wearable sensors.
Study predicts heart failure patient survival using stacked ensemble ML.
problem Predicting survival of heart failure patients.
method Collect and analyze patient data, apply SMOTE, use K-Means, Fuzzy C-Means clustering, Random Forest, XGBoost, Decision Tree, and propose a stacked ensemble model.
result Supervised ML algorithms outperform unsupervised models, achieving high accuracy and F1 score.
Photoplethysmogram (PPG) is increasingly used to provide monitoring of the cardiovascular system under ambulatory conditions. Wearable devices like smartwatches use PPG to allow long term unobtrusive monitoring of heart rate in free living conditions. PPG based heart rate measurement is unfortunately highly susceptible…
Heart disease is the leading cause of death, and experts estimate that approximately half of all heart attacks and strokes occur in people who have not been flagged as "at risk." Thus, there is an urgent need to improve the accuracy of heart disease diagnosis. To this end, we investigate the potential of using data ana…
Cardiovascular Disease (CVD) is considered as one of the principal causes of death in the world. Over recent years, this field of study has attracted researchers' attention to investigate heart sounds' patterns for disease diagnostics. In this study, an approach is proposed for normal/abnormal heart sound classificatio…
Developed shrinkage methods for Poisson regression models with experts to handle multicollinearity.
problem Multicollinearity in Poisson regression models with experts.
method Ridge and Liu-type shrinkage methods.
result Shrinkage methods offer more reliable estimates for coefficients in multicollinearity.
Heart diseases constitute a global health burden, and the problem is exacerbated by the error-prone nature of listening to and interpreting heart sounds. This motivates the development of automated classification to screen for abnormal heart sounds. Existing machine learning-based systems achieve accurate classificatio…
Study examines heart and football-shaped metrics, verifying geometric structure.
problem Analyzing reducible spherical conical metrics and their geometric properties.
method Examined 1-parameter heart shape and 3-parameter football shape families, verified structure theorem, used explicit metric and geodesic calculations.
result Naturally arise from Abelian differentials of the third kind, offer new evidence for spherical geometry and complex analytic structure interaction.
New scalable method balances hospital profit status and heart attack outcomes.
problem Balancing covariate distributions and minimizing weight dispersion in large datasets.
method Combines kernel basis expansion and convex optimization for efficient and flexible weighting.
result For-profit hospitals use interventional cardiology similarly to other hospitals but have higher mortality and readmission rates.
We consider the problem of locating a point-source heart arrhythmia using data from a standard diagnostic procedure, where a reference catheter is placed in the heart, and arrival times from a second diagnostic catheter are recorded as the diagnostic catheter moves around within the heart. We model this situation as a …
Improved heart rate and activity recognition with low-power wrist sensors.
problem Challenges in battery life, cost, and sensor performance in wrist-worn sensing applications.
method Used photoplethysmography (PPG) for heart rate and activity recognition, applying transfer learning and CNNs.
result Low sampling frequencies (5 Hz and 10 Hz) achieved good performance in heart rate and activity recognition.
Study improves CAD diagnosis accuracy by selecting significant features.
problem Improving accuracy of CAD diagnosis through feature selection.
method Integrated machine learning approach using random trees (RTs), C5.0, SVM, and CHAID.
result Random trees model outperforms other models in CAD diagnosis.
Proposes a novel anomaly detection method for echocardiogram videos.
problem Anomaly detection in echocardiogram videos.
method Dynamic Variational Trajectory Models (TVAE-C, TVAE-R, TVAE-S) trained on healthy infant echocardiogram videos.
result Superior performance in detecting congenital heart defects and pulmonary hypertension.
Study identifies mental stress in firefighters using heart rate variability data.
problem Unsupervised identification of mental stress in firefighters from heart rate variability data.
method Exploration and comparison of three unsupervised methods: K-Means, convolutional autoencoders, and LSTM autoencoders.
result Convolutional and LSTM autoencoders successfully stratify stressed versus normal samples using HRV markers.
Machine learning predicts exercise load from heart rate data post-exercise.
problem Monitoring energy expenditure in real life.
method Machine learning methods (linear regression, etc.) applied to heart rate data.
result Random forest and k-nearest neighbors classifiers predict load levels accurately.
AI-assisted heart disease diagnosis reduces misdiagnosis and saves lives.
problem Misdiagnosis of heart disease leads to unnecessary deaths.
method Developed an AI application using ML and DNN algorithms on a dataset from the Cleveland Clinic Foundation.
result DNN model achieved a 92% accuracy rate, reducing misdiagnosis.
Novel method segments heart sound signals using LSTMs with attention.
problem Heart sound segmentation for diagnostic applications.
method Bidirectional LSTMs with attention mechanisms.
result State-of-the-art performance on multiple benchmarks.
Interpretable survival analysis improves heart failure risk prediction.
problem Improving heart failure risk prediction using survival analysis.
method Survival stacking, ControlBurn, Explainable Boosting Machines.
result Achieves state-of-the-art performance and provides novel insights.
We developed a new approach for the analysis of physiological time series. An iterative convolution filter is used to decompose the time series into various components. Statistics of these components are extracted as features to characterize the mechanisms underlying the time series. Motivated by the studies that show …
AI detects heart disease from ECGs with improved interpretability and performance.
problem Undiagnosed structural heart disease due to high cost and accessibility of echocardiography.
method Generalized additive model integrating clinically meaningful ECG predictors.
result Improved AUROC, AUPRC, and F1 score compared to deep-learning baselines.
Study shows DL models trained on healthy subjects perform worse on patients' ECG data.
problem Inefficiency of DL models on heterogeneous datasets for heart beat detection.
method Investigated and evaluated the use of Transfer Learning to adapt DL models to different datasets.
result Transfer Learning improves classification performance on small sample size datasets.
Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing preventive measures are potential solutions to improve cancer patients's quality of …
This paper proposes a framework based on deep convolutional neural networks (CNNs) for automatic heart sound classification using short-segments of individual heart beats. We design a 1D-CNN that directly learns features from raw heart-sound signals, and a 2D-CNN that takes inputs of two- dimensional time-frequency fea…
A CNN-based method improves DTI of the human heart, compensating for motion.
problem Signal loss due to heart motion in DTI.
method Invertible Wavelet Scattering using CNN.
result Effective motion compensation and improved fiber structures.
ECGDetect uses deep learning to detect ischemia in heart ECGs.
problem Detecting early signs of acute coronary syndrome in patients.
method Developed a deep learning model using the LTST database.
result Deep neural network achieved 90.31% ROC-AUC, 89.34% sensitivity, 87.81% specificity.
The study uses transfer learning to compare surgical outcomes across racial/ethnic subgroups.
problem Difficulty in comparing surgical outcomes due to racial/ethnic and geographic differences.
method Causal inference framework and transfer learning to incorporate data from multiple populations.
result Racial and ethnic differences in surgical outcomes are found, with non-Hispanic Black patients experiencing wide variability.
Deep learning speeds up whole heart MRI to 30 seconds.
problem Long acquisition times in whole heart MRI.
method Deep learning, specifically a 3D residual U-Net, to reconstruct high-resolution images from low-resolution data.
result Super-resolution images show better edge sharpness and fewer artefacts than low-resolution images.
Bayesian neural networks improve SHD classification and uncertainty quantification.
problem Improving screening for structural heart disease using noninvasive ECG and echocardiography.
method Comparing frequentist and Bayesian neural network classifiers on the EchoNext dataset.
result Bayesian classifiers provide more robust uncertainty quantification.
JigSaw discovers high-order interactions from random forests.
problem Identifying complex interactions in biological data.
method Random forest structure analysis to find high-order interactions.
result JigSaw can explain outcomes in heart disease and breast cancer.
Machine learning improves CHD screening accuracy from 70% to 87.7%.
problem Predicting coronary heart disease using echocardiography and clinical features.
method Ensemble machine learning approach with model stacking and two-step stacking.
result Improved CHD classification accuracy from 70% to 87.7%.
Improved robustness of 1D CNNs for heart arrhythmia classification.
problem Improving the robustness of 1D CNNs for classification tasks.
method Parameterization using Cayley transform and controllability Gramian for Lipschitz-bounded CNNs.
result Improved robustness of trained Lipschitz-bounded 1D CNNs for heart arrhythmia classification.
Causal analysis reveals regional discrepancies in TOPCAT trial results.
problem Inconclusive results in TOPCAT trial for heart failure treatment.
method Causal discovery methods with domain knowledge integration.
result Significant causal effects shown for some subgroups globally.
The reactions of the human body to physical exercise, psychophysiological stress and heart diseases are reflected in heart rate variability (HRV). Thus, continuous monitoring of HRV can contribute to determining and predicting issues in well-being and mental health. HRV can be measured in everyday life by consumer wear…
Fluctuations in heart rate are intimately tied to changes in the physiological state of the organism. We examine and exploit this relationship by classifying a human subject's wake/sleep status using his instantaneous heart rate (IHR) series. We use a convolutional neural network (CNN) to build features from the IHR se…
An electrocardiogram (EKG) is a common, non-invasive test that measures the electrical activity of a patient's heart. EKGs contain useful diagnostic information about patient health that may be absent from other electronic health record (EHR) data. As multi-dimensional waveforms, they could be modeled using generic mac…
Random shuffle method boosts HF dataset size 10-21 times.
problem Narrow dataset cardinality in HF clinical studies.
method Random shuffle method to enhance dataset size.
result Enhanced HF dataset size 10-21 times.
Deep learning predicts heart failure readmission from clinical notes.
problem Predicting and preventing heart failure readmission.
method Convolutional Neural Networks (CNN) trained on clinical notes.
result Deep learning models outperform traditional machine learning methods in readmission prediction.
Study reviews machine learning techniques for stress monitoring.
problem Improving accuracy of stress monitoring devices.
method Reviewed machine learning techniques for various stress indicators.
result Choosing the right classifier depends on multiple factors.
Improving the precision of heart diseases detection has been investigated by many researchers in the literature. Such improvement induced by the overwhelming health care expenditures and erroneous diagnosis. As a result, various methodologies have been proposed to analyze the disease factors aiming to decrease the phys…
Method synthesizes 4D CMR images from XCAT model using GAN and SPADE.
problem Synthesizing realistic 4D CMR images with annotations and adaptable styles.
method Hybrid GAN approach with XCAT anatomical ground truth and SPADE for semantic preservation.
result Synthesized images with modality-specific features learned from real CMR data.
This paper aims to classify a single PCG recording as normal or abnormal for computer-aided diagnosis. The proposed framework for this challenge has four steps: preprocessing, feature extraction, training and validation. In the preprocessing step, a recording is segmented into four states, i.e., the first heart sound, …