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arXiv research

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169,051 papers · 148 categories

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48 results for Digital Pathology

We propose a new model for digital pathology segmentation, based on the observation that histopathology images are inherently symmetric under rotation and reflection. Utilizing recent findings on rotation equivariant CNNs, the proposed model leverages these symmetries in a principled manner. We present a visual analysi…

2018-06-08abs ↗pdf ↗

Deep Learning model diagnoses four lymphoma categories with high accuracy.

problem Automated detection of lymphoma categories using digital pathology images.
method Convolutional neural network algorithm trained on 128 cases of lymph node images.
result Excellent diagnostic accuracy (95% image-by-image, 10% set-by-set).

Model learns cancer tissue images onto a low-dimensional space revealing tissue characteristics.

problem Improving cancer diagnosis through high-fidelity digital pathology.
method Deep generative model using PathologyGAN to map real images onto a latent space.
result Latent space encodes morphological characteristics and reveals distinct tissue clusters.

This paper proposes synthetic augmentation for nuclei image segmentation in medical pathology.

problem Rare and time-consuming labeling of tumor nuclei images for semantic segmentation.
method Label-to-image translation to generate synthetic images.
result Synthetic augmentation improves segmentation accuracy.

New strategies help CNNs recognize tissue features across different stains.

problem Training deep learning models for images with multiple stains is challenging and expensive.
method Presented unsupervised training strategies that leverage one staining modality to improve performance on images with multiple stains.
result CNNs trained with these strategies outperform standard training methods on images with multiple stains.

Novel fusion network combines polarization and radiomics features for liver cancer classification.

problem Challenges in histopathological diagnosis of HCC and ICC.
method Two-tier fusion approach: feature-level and classification-level.
result Significantly enhances classification accuracy, even at reduced resolutions.

Probabilistic method identifies Purkinje network from ECG data.

problem Challenging task of identifying Purkinje conduction system in heart.
method Bayesian optimization and approximate Bayesian computation for probabilistic identification.
result Generates a population of plausible Purkinje networks fitting ECG within tolerance.

Accurate and robust cell nuclei classification is the cornerstone for a wider range of tasks in digital and Computational Pathology. However, most machine learning systems require extensive labeling from expert pathologists for each individual problem at hand, with no or limited abilities for knowledge transfer between…

2016-06-02abs ↗pdf ↗

Aims to integrate AI and modelling for patient health forecasting.

problem Personalized, precise treatment plans for patients.
method Graph neural network (GNNs) and generative adversarial network (GANs) for probabilistic simulations.
result Demonstrated integration of molecular data for predicting physiological state evolution.

This study investigates how much knowledge from natural images can be transferred to pathology images.

problem Quantifying how much knowledge from natural images can be transferred to pathology images.
method Proposes a framework to quantify knowledge gain by a particular layer, conducts empirical investigation in pathology image centered transfer learning.
result Early layers of deep models can transfer knowledge to pathology image classification tasks.

Study classifies pathology reports using TF-IDF features and machine learning.

problem Classifying pathology reports for cancer surveillance and diagnostic workflow.
method Extracted TF-IDF features from pathology reports and classified them using SVM, XGBoost, and Logistic Regression.
result XGBoost achieved 92% accuracy in classifying pathology reports.

This paper characterizes VAE training pathologies and their effects on tasks.

problem Characterizing VAE training pathologies and their impact on downstream tasks.
method Concretely characterizing conditions for VAE training pathologies and their connection to specific downstream tasks.
result Connects VAE training pathologies to specific downstream tasks like learning compressed and disentangled representations, adversarial robustness, and semi-supervised learning.

Proposes deep learning method for GCI detection from pathological speech.

problem Detecting glottal closure instants (GCI) in pathological acoustic speech.
method Convolutional neural network with fused deep acoustic speech and linear prediction residual features.
result Significantly better than state-of-the-art methods in GCI detection.

Semi-supervised learning classifies cardiac pathology using motion features from cine MRI.

problem Classifying cardiac pathology based on motion features from cine MRI.
method Semi-supervised learning of apparent flow to generate motion features from non-segmented images.
result The model achieves 95% classification accuracy on ACDC test set.

Novel approach characterizes deep neural networks at initialization.

problem Characterizing the behavior of deep neural networks at initialization.
method A novel approach considering the evolution of statistical moments of signal and noise.
result Established that skip-connections in residual networks lead to well-behaved moments and no pathology.

Batch normalization in the last layer reduces sharpness in wide neural networks.

problem Pathological sharpness in wide neural networks.
method Quantifying the geometry of the parameter space using Fisher information matrix and analyzing deep neural networks with random initialization.
result Batch normalization in the last layer significantly decreases pathological sharpness under specific conditions.

SAPSAM trains CNNs on lung CTs with binary labels, improving CPA detection and localization.

problem Chronic Pulmonary Aspergillosis (CPA) detection and localization on CT scans using binary labels.
method Binary labels, average intensity projections, 2D RGB-like images, hierarchical CNN architectures.
result High classification accuracy, precise localization, predictive power of 2-year survival.

KL-regularized RL from expert demos can lead to slow, unstable learning.

problem Pathological training dynamics in KL-regularized RL from expert demonstrations.
method Empirical analysis and non-parametric behavioral reference policies.
result KL-regularized RL can be significantly improved by using non-parametric behavioral policies.

Paper develops a BERT-based classifier to reduce pathology report annotation workload.

problem Manual annotation of pathology reports is labor-intensive and time-consuming.
method Developed an automatic text classifier using BERT and introduced a human-centric metric to identify low-confidence cases.
result The model reduces manual annotation workload by 80% to 98%.

Generative model for morphological continuum of normal and pathological states.

problem Identifying trends and features that separate normality and pathology in biomedical images.
method Wasserstein Auto-encoder with HSIC regularization for latent features.
result Model generates a continuum of morphological changes corresponding to side information.

The paper presents algorithms for diagnosing Pathological Myopia and detecting retinal structures.

problem Diagnosing Pathological Myopia and detecting retinal structures in fundus images.
method The approach uses Deep Learning techniques, including transfer learning with Xception and YOLO architecture.
result The method has shown satisfactory results in the Pathologic Myopia Challenge.

New analysis explains pathology of deep Gaussian processes.

problem Pathology of deep Gaussian processes reduces learning capacities with increased layers.
method Study nonlinear dynamic systems corresponding to DGPs, derive recurrence relations.
result Provide tighter bounds and rate of convergence for dynamic systems.

Causal methods for GRN inference from single-cell data often fail in real-world benchmarks.

problem Understanding when and why causal methods for GRN inference from single-cell data fail in real-world benchmarks.
method Introduced a controlled diagnostic framework to isolate and measure seven pathologies.
result Causal methods dominate in clean and structurally favorable regimes but fail in specific pathologies.

For test configurations, the Donaldson-Futaki invariant F_1 is well-known. In this note, its refinement will be discussed. Then we see that Li-Xu's pathology doesn't occur, since their example of a non-normal test configuration, with trivial normalization, actually has non-vanishing F_1 in this refined sense.

2013-05-28abs ↗pdf ↗

New test identifies specific biological parameters for personalized CVD detection.

problem Ineffectual pathology tests fail to consider platelet activation and inter-individual variability.
method Stochastic platelet deposition model and approximate Bayesian computation with discriminative summary statistics.
result Inferred parameters help identify specific biological parameters for personalized CVD detection.

Method treats pseudo healthy synthesis as a factor decomposition problem.

problem Creating a healthy-looking image from a pathological one.
method Adversarial training with paired or unpaired settings, combining two factors (healthy and disease) to reconstruct the input.
result Method outperforms conditional GAN and CycleGAN in generating pseudo healthy images.

Study reveals pathological eigenvalue spectra in FIM and its variants of DNNs.

problem Understanding sharp local shapes in DNN loss landscapes.
method Analysis of FIM and its variants in regression and classification DNNs.
result Pathological eigenvalue spectra appear in FIM and its variants, indicating sharp local shapes in specific directions.

Automatic Chemical Design is a framework for generating novel molecules with optimized properties. The original scheme, featuring Bayesian optimization over the latent space of a variational autoencoder, suffers from the pathology that it tends to produce invalid molecular structures. First, we demonstrate empirically …

2017-09-16abs ↗pdf ↗