Framework detects and classifies multi-label RBC images from microscopic images.
problem Challenges in separating touching or overlapping cells for classification.
method Region proposal model + CNN feature extraction + multi-label prediction networks.
result Framework achieves good performance in automatic cell detection and classification.
Paper analyzes learning from ghost imaging without reconstruction bottleneck.
problem High-speed cell classification bottleneck in ghost cytometry.
method Theoretical analysis of learning from ghost imaging without reconstruction.
result Theoretical analysis supports learning from ghost imaging without reconstruction.
Few-shot cell segmentation from diverse sources to target domain.
problem Efficient cell segmentation from limited annotated images.
method Meta-learning combining cross-domain tasks and invariant representation.
result Promising results from 1-10-shot learning on public databases.
Counting and classifying blood cells is an important diagnostic tool in medicine. Support Vector Machines are increasingly popular and efficient and could replace artificial neural network systems. Here a method to classify blood cells is proposed using SVM. A set of statistics on images are implemented in C++. The MPE…
Deep CNN model predicts neuronal cell health from images.
problem Predicting the biological activity of chemical compounds on neuronal cells.
method Deep convolutional neural network (CNN) with residual connections.
result Achieved 99.6% accuracy in distinguishing treated from untreated cells.
We present a conditional generative model to learn variation in cell and nuclear morphology and the location of subcellular structures from microscopy images. Our model generalizes to a wide range of subcellular localization and allows for a probabilistic interpretation of cell and nuclear morphology and structure loca…
New deep learning method classifies cancer cells from small training sets.
problem Small training sets in medical imaging.
method Hybrid of transfer learning and GANs.
result 90-99% accuracy in classifying healthy and cancer cells.
TIMELY improves consistency in labeling blood cell images.
problem Inconsistent labeling of blood cells in microscopy images leads to unreliable diagnoses.
method TIMELY combines pseudotime inference and hidden Markov trees to correct labeling mistakes.
result TIMELY outperforms baseline methods in identifying and correcting inconsistent labels.
TUNet improves protein classification in cell images.
problem Classifying specific proteins in human cells using microscopy images.
method TUNet model incorporating segmentation maps for improved classification.
result TUNet achieves competitive performance in protein classification.
Novel framework for whole-slide blood cell segmentation.
problem Semantic segmentation of whole-slide blood cell images.
method Convolutional encoder-decoder framework with VGG-16 feature extraction.
result Outstanding accuracy (97.18% global accuracy) in classwise segmentation.
A new model for complex cells accounts for insensitivity to image shifts.
problem Complex cells' response to image shifts.
method Linear combination of Gaussian derivatives at a single position.
result Maximum response insensitive to small shifts of the image.
DISPR uses diffusion models to predict 3D cell shapes from 2D images.
problem Predicting 3D cell shapes from 2D microscopy images.
method Diffusion model trained to predict 3D shapes from 2D microscopy images as a prior.
result Adding DISPR predictions to minority cell classes improves classification accuracy.
Lung cancer continues to be a major healthcare challenge with high morbidity and mortality rates among both men and women worldwide. The majority of lung cancer cases are of non-small cell lung cancer type. With the advent of targeted cancer therapy, it is imperative not only to properly diagnose but also sub-classify …
C2G-Net improves image classification of similar objects like cells.
problem Classifying images with many similar objects efficiently and interpretably.
method Combines image compression and a CNN with reduced parameters.
result C2G-Net achieves similar accuracy to conventional CNNs but with reduced training time and improved interpretability.
COOS-7 dataset benchmarks image classifier generalization.
problem Measuring generalization of image classifiers to out-of-sample datasets.
method Created COOS-7 dataset with varying covariate shifts; benchmarked multiple models.
result All classifiers failed to generalize to datasets with greater covariate shifts.
In this paper, we propose a novel application of Generative Adversarial Networks (GAN) to the synthesis of cells imaged by fluorescence microscopy. Compared to natural images, cells tend to have a simpler and more geometric global structure that facilitates image generation. However, the correlation between the spatial…
Automatically counts microglial cells in rat spinal cord images, providing precise counts and uncertainty estimates.
problem Counting microglial cells in small, heterogeneous datasets is time-consuming and requires extensive training.
method Pre-processing to filter images, designing a non-parametric, non-linear kernel counter, providing uncertainty estimation.
result The method can provide precise counts and uncertainty estimates in small datasets, even with expert opinions.
We explore visual representations of tilings corresponding to Schläfli symbols. In three dimensions, we call these tilings "honeycombs". Schläfli symbols encode, in a very efficient way, regular tilings of spherical, euclidean and hyperbolic spaces in all dimensions. In three dimensions, there are only a finite number …
Cataloging the neuronal cell types that comprise circuitry of individual brain regions is a major goal of modern neuroscience and the BRAIN initiative. Single-cell RNA sequencing can now be used to measure the gene expression profiles of individual neurons and to categorize neurons based on their gene expression profil…
Better neural arithmetic logic units improve cell counting model generalization.
problem Neural networks struggle with high cell counts outside training data range.
method Introduced Neural Arithmetic Logic Units (NALU) for arithmetic operations in existing architectures.
result Improved cell counting accuracy for higher numeric ranges with better generalization.
A new image completion method inspired by brain cells.
problem Image restoration from corrupted data.
method Biologically-inspired sub-Riemannian model with frequency and phase.
result Completion of two-dimensional images using cortical cell responses.
Multi-StyleGAN simulates live cell microscopy imagery.
problem Costly and complex live cell experiments.
method Generative adversarial network (GAN) synthesizing multi-domain time-lapse images.
result Captures biophysical factors and time dependencies in cell imagery.
A fundamental operation in many vision tasks, including motion understanding, stereopsis, visual odometry, or invariant recognition, is establishing correspondences between images or between images and data from other modalities. We present an analysis of the role that multiplicative interactions play in learning such …
Enhances high-throughput imaging of microtubule networks, improving clarity and consistency.
problem Fluorescence noise obscures microtubule structures in high-throughput imaging.
method CycleGAN learning to enhance low-resolution images of microtubule networks.
result CycleGAN effectively identifies microtubules with high accuracy (0.93+ AUC-ROC).
Profiling cellular phenotypes from microscopic imaging can provide meaningful biological information resulting from various factors affecting the cells. One motivating application is drug development: morphological cell features can be captured from images, from which similarities between different drug compounds appli…
Study uses deep learning to detect BCCs in high-res histopathological images.
problem Detecting BCCs in high-resolution, weakly labeled histopathological images.
method Attention-based deep learning models to process ultra-high resolution images with weak labels.
result Attention-based models achieve almost perfect classification performance (AUC of 0.99).
We study the problem of instance segmentation in biological images with crowded and compact cells. We formulate this task as an integer program where variables correspond to cells and constraints enforce that cells do not overlap. To solve this integer program, we propose a column generation formulation where the prici…
This study automates blood cell classification using computer vision.
problem Automated detection and classification of white blood cells.
method Color-based segmentation, morphological processing, feature extraction, PCA, Unsupervised and Supervised learning algorithms, Deep Convolutional Neural Networks.
result Identification of robust algorithms for automated blood cell classification.
New method extracts biological concepts from cell microscopy images.
problem Extracting meaningful concepts from vision foundation models trained on cell microscopy images.
method Sparse dictionary learning (DL) combined with PCA whitening pre-processing.
result Successfully retrieved biologically meaningful concepts like cell types and genetic perturbations.
New CNN approach detects cell nuclei with prior information.
problem Challenges in detecting cell nuclei due to image quality and morphology diversity.
method Develops SP-CNN with trainable shape prior layer to guide CNN learning.
result TSP-CNN outperforms state-of-the-art alternatives on challenging datasets.
MuLANN tackles multi-domain learning with adversarial approach.
problem Automated microscopy data with domain bias.
method Semi-supervised multi-domain learning with MuLANN.
result Improves state of the art on image benchmarks and bioimage dataset.
New method learns transport cost from subset correspondence.
problem Aligning multiple datasets with accurate cost functions.
method End-to-end optimizer (OT-SI) that differentiates through Sinkhorn algorithm.
result Substantially outperforms state-of-the-art benchmarks.
AutoShrink optimizes neural architectures by shrinking cell structures.
problem Resource constraints in deploying DNNs on mobile devices.
method Topology-aware node-based Neural Architecture Search (NAS).
result AutoShrink achieves up to 48% parameter reduction and 34% MACs savings.
Detection of cell nuclei in microscopic images is a challenging research topic, because of limitations in cellular image quality and diversity of nuclear morphology, i.e. varying nuclei shapes, sizes, and overlaps between multiple cell nuclei. This has been a topic of enduring interest with promising recent success sho…
We describe a family of 4-dimensional hyperbolic orbifolds, constructed by deforming an infinite volume orbifold obtained from the ideal, hyperbolic 24-cell by removing two walls. This family provides an infinite number of infinitesimally rigid, infinite covolume, geometrically finite discrete subgroups of the isometry…
New methods predict walking patterns from accelerometer data.
problem Predicting individuals from walking data.
method Machine learning, inferential methods, multivariate functional regression.
result Prediction accuracy varies from 41% to 98%.
Deep neural network improves malaria detection from red blood cells.
problem Improving malaria detection from red blood cell images.
method End-to-end deep learning approach using convolutional neural networks.
result Best model achieves 97.77% accuracy.
Tree-SNE combines t-SNE and hierarchical clustering for data visualization.
problem Data visualization and clustering in complex datasets.
method Stacked one-dimensional t-SNE embeddings and alpha-clustering.
result Effective hierarchical clustering and visualization of various datasets.
QANet estimates image segmentation quality without human inspection.
problem Quantitative evaluation of image segmentation quality.
method QANet is a Quality Assurance Network that solves a regression problem to estimate quality measures.
result QANet accurately estimates segmentation quality with respect to ground truth.
Input-cell attention improves RNN saliency detection over time.
problem Vanishing saliency in RNNs makes them unreliable for detecting important features at arbitrary time intervals.
method Proposes input-cell attention, a novel RNN cell structure that uses a fixed-size matrix embedding to attend to different inputs from current or previous time steps.
result Input-cell attention produces a saliency map that can detect important features regardless of their occurrence in time.
NAS favors wide and shallow cell structures, leading to fast convergence but not necessarily better generalization.
problem Understanding and improving the architectures generated by NAS algorithms.
method Empirical and theoretical study of existing NAS algorithms (DARTS, ENAS) and their architectures.
result Existing NAS algorithms favor wide and shallow cell structures, leading to fast convergence but not necessarily better generalization.
We study natural bases for two constructions of the irreducible representation of the symmetric group corresponding to [n,n,n]: the {\em reduced web} basis associated to Kuperberg's combinatorial description of the spider category; and the {\em left cell basis} for the left cell construction of Kazhdan and Lusztig. I…
Proposes a new LSTM gate structure using bivariate Beta distribution.
problem Inflexibility of sigmoid gates in modeling multi-modality and skewness, and lack of modeling correlation between gates.
method Introduces a bivariate Beta distribution gate structure within LSTM cells.
result Empirically shows higher gradient values and improved model performance.
We show that there are homotopy equivalences h:N→M between closed manifolds which are induced by cell-like maps p:N→X and q:M→X but which are not homotopic to homeomorphisms. The phenomenon is based on construction of cell-like maps that kill certain L-classes. The image space in these construc…
System detects and classifies skin cancer using CNN.
problem Early detection and classification of skin cancer is challenging and costly.
method Used MNIST HAM-10000 dataset, image processing, deep learning (CNN), and transfer learning (ResNet).
result CNN model achieved 0.88 precision, 0.74 recall, and 0.77 f1-score.
Topology-enhanced loss improves 3D object reconstruction from 2D images.
problem Challenges in reconstructing 3D objects from 2D images, especially capturing shape information.
method Integrates multi-scale topological features into the reconstruction loss using cubical complexes and optimal transport distance.
result Topology-aware loss substantially improves 3D reconstruction quality.
Deep feature fusion improves mitosis counting accuracy.
problem Manual mitosis counting by pathologists is time-consuming and inconsistent.
method Combines Faster R-CNN for object detection with UNet segmentation features and RGB image features.
result Achieved an F-score of 0.508 on mitosis counting challenge dataset, outperforming state-of-the-art methods.
In \cite{rigidity}, Luo introduced a ψλ edge invariant which turns out to be a coordinate of the Teichmüller space of a surface with boundary. And he proved that for λ≥0, the image of the Teichmüller space under ψλ edge invariant coordinate is an open cell. In this paper we verify his conjecture that for $λ…