Weakly supervised model segments tumor areas from whole slide images.
problem Training segmentation models on noisy labeled data from whole slide images.
method Online patch sampling and robust KL divergence extension.
result Model successfully segments tumor areas with strong morphological consistency.
Novel framework for whole-slide blood cell segmentation.
problem Semantic segmentation of whole-slide blood cell images.
method Convolutional encoder-decoder framework with VGG-16 feature extraction.
result Outstanding accuracy (97.18% global accuracy) in classwise segmentation.
Recent studies have shown promising results in using Deep Learning to detect malignancy in whole slide imaging. However, they were limited to just predicting positive or negative finding for a specific neoplasm. We attempted to use Deep Learning with a convolutional neural network algorithm to build a lymphoma diagnost…
An important part of Digital Pathology is the analysis of multiple digitised whole slide images from differently stained tissue sections. It is common practice to mount consecutive sections containing corresponding microscopic structures on glass slides, and to stain them differently to highlight specific tissue compon…
Histopathology tissue samples are widely available in two states: paraffin-embedded unstained and non-paraffin-embedded stained whole slide RGB images (WSRI). Hematoxylin and eosin stain (H&E) is one of the principal stains in histology but suffers from several shortcomings related to tissue preparation, staining proto…
CNN-based prostate cancer grading improves accuracy and efficiency.
problem Manual Gleason grading by pathologists is time-consuming and prone to errors.
method Patch-Based Image Reconstruction (PBIR), Distribution Correction (DC), Quadratic Weighted Mean Square Error (QWMSE).
result Achieved superior expert-level performance (0.8885 quadratic-weighted kappa coefficient).
In recent years, many publications showed that convolutional neural network based features can have a superior performance to engineered features. However, not much effort was taken so far to extract local features efficiently for a whole image. In this paper, we present an approach to compute patch-based local feature…
Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in the field of pathology, we have created an intuitive interface which utilizes the…
Dropout improves MIL performance on noisy WSI classification.
problem Noisy feature embeddings and weak supervision in MIL for WSI classification.
method Empirical exploration of dropout in MIL, proposing MIL-Dropout.
result MIL-Dropout boosts MIL performance with minimal computational cost.
Transfer learning from breast histopathology improves prostate cancer detection.
problem Insufficient prostate histopathology datasets for training.
method Transfer learning from breast histopathology images.
result Proposed approach outperforms transfer learning from ImageNet dataset.
Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast whole-slide-images of extreme digital resolution (100,0002 pixels) across multiple…
Deep learning model diagnoses celiac disease severity from intestinal biopsy images.
problem Diagnosing celiac disease severity from biopsy images, especially mild cases.
method Deep residual networks trained on a modified Marsh score histological scoring system.
result Model achieved AUC > 0.96 in all classes for CD severity classification.
Study uses deep learning to detect BCCs in high-res histopathological images.
problem Detecting BCCs in high-resolution, weakly labeled histopathological images.
method Attention-based deep learning models to process ultra-high resolution images with weak labels.
result Attention-based models achieve almost perfect classification performance (AUC of 0.99).
Evaluates deep learning models in histopathology for robustness and classification strategies.
problem Lack of comprehensive evaluation of histopathology models beyond accuracy.
method Developed a new methodology to evaluate models on five histopathology datasets, including vision transformers and CNNs.
result Identified insights into cancer classification strategies and robustness against stain variations.
Study uses image analysis to predict MSI status in tumors.
problem Challenges in distinguishing MSI from its counterpart.
method Interpretable pathological image analysis strategies using Haematoxylin and eosin-stained images.
result Strategies achieve decent performance in MSI prediction.
Volumetric analysis of brain ventricle (BV) structure is a key tool in the study of central nervous system development in embryonic mice. High-frequency ultrasound (HFU) is the only non-invasive, real-time modality available for rapid volumetric imaging of embryos in utero. However, manual segmentation of the BV from H…
Hierarchical CNNs improve diagnosis of GI diseases from histopathological images.
problem Diagnosing GI diseases from histopathological images is challenging due to heterogeneity and shared features.
method Embedded a class hierarchy into a VGGNet to address the hierarchical structure of GI diseases.
result The hierarchical model achieved better results than a flat model for multi-category diagnosis of GI disorders.
Ideal triangulations of 3-manifolds are shown equivalent up to certain moves.
problem Equivalence of ideal triangulations in 3-manifolds.
method Using branched triangulations and transit equivalences, the paper shows that ideal triangulations are equivalent up to certain moves.
result Ideal triangulations of 3-manifolds are equivalent up to certain moves.
This paper benchmarks OoDD methods for medical imaging.
problem Medical models trained for one domain may fail on images from a different domain.
method Defined 3 categories of OoD examples and benchmarked methods in 3 medical imaging domains.
result Simple binary classifier on feature representation yields best accuracy and AUPRC.
MEM learns set functions from permutation-invariant data.
problem Learning from sets of instances with labels only on sets, not instances.
method Memory-based Exchangeable Model (MEM) with self-attention mechanism.
result Achieved 84.84% accuracy on lung cancer classification.
Manual count of mitotic figures, which is determined in the tumor region with the highest mitotic activity, is a key parameter of most tumor grading schemes. It can be, however, strongly dependent on the area selection due to uneven mitotic figure distribution in the tumor section.We aimed to assess the question, how s…
Deep learning speeds up whole heart MRI to 30 seconds.
problem Long acquisition times in whole heart MRI.
method Deep learning, specifically a 3D residual U-Net, to reconstruct high-resolution images from low-resolution data.
result Super-resolution images show better edge sharpness and fewer artefacts than low-resolution images.
A sliding surface stabilizes rigid body attitude control.
problem Stabilizing rigid body attitude control robustly.
method Proposed sliding surface as Lie subgroup, designed sliding-mode controller.
result Closed-loop system is robust against disturbances and unwinding.
Automatically counts microglial cells in rat spinal cord images, providing precise counts and uncertainty estimates.
problem Counting microglial cells in small, heterogeneous datasets is time-consuming and requires extensive training.
method Pre-processing to filter images, designing a non-parametric, non-linear kernel counter, providing uncertainty estimation.
result The method can provide precise counts and uncertainty estimates in small datasets, even with expert opinions.
New robustness certificates for streaming models with a sliding window.
problem Applying robustness certificates to streaming data with correlated inputs.
method Deriving robustness certificates for models using a sliding window over a sequence of potentially correlated inputs.
result Guarantees hold for the average model performance across the entire stream, independent of stream size.
Brain imaging analysis on clinically acquired computed tomography (CT) is essential for the diagnosis, risk prediction of progression, and treatment of the structural phenotypes of traumatic brain injury (TBI). However, in real clinical imaging scenarios, entire body CT images (e.g., neck, abdomen, chest, pelvis) are t…
A CNN-based method detects and counts corn kernels from images.
problem Manual counting of corn kernels is labor-intensive and prone to error.
method Sliding window approach with CNN for detection and NMS for overlapping removal.
result The method successfully detects and counts kernels with low error.
Proposes manifold-based unsupervised anomaly detection for visual data.
problem Rare anomalies in unlabeled data.
method Constant curvature manifolds, hyperspherical Variational Auto-Encoders (VAE) with gyroplane layer.
result State-of-the-art results on visual anomaly benchmarks and histopathology.
Satellite images improve real-estate price predictions.
problem Improving accuracy of real-estate price predictions.
method Used convolutional neural networks (CNN) to incorporate satellite image data.
result CNN model trained on satellite images and structured data performs 7% better in MAE.
Study confirms sparse coding in whole brain using MRI data.
problem Sparse coding in the whole brain's neural activities.
method Applied various matrix factorization methods to fMRI data.
result Sparse coding hypothesis in information representation in the whole human brain is confirmed.
A 3-stage method enhances hyperspectral image classification accuracy.
problem Classifying detailed classes in hyperspectral images with limited labeled data.
method Uses Nested Sliding Window and PCA for spatial consistency, SVM for spectral estimation, and TV model for spatial smoothing.
result Our method outperforms state-of-the-art algorithms, especially in scenarios with small training sets.
Automated malaria diagnosis from field slides achieves accurate results.
problem Challenges in analyzing field-prepared thin blood film microscopy images.
method Fully automated framework using machine learning, including CNNs trained on diverse field samples.
result Results are close to sufficient for drug resistance monitoring and clinical use-cases.
The paper analyzes the sliding regret of stochastic bandit algorithms.
problem Measuring the one-shot behavior of no-regret algorithms in stochastic bandits.
method Introducing sliding regret to measure the worst pseudo-regret over a time-window.
result Randomized methods have optimal sliding regret, while index policies have the worst possible sliding regret.
To alleviate the burden of gathering detailed expert annotations when training deep neural networks, we propose a weakly supervised learning approach to recognize metastases in microscopic images of breast lymph nodes. We describe an alternative training loss which clusters weakly labeled bags in latent space to inform…
Presentations for involutions on non-orientable surfaces up to genus 5.
problem Representing involutions on non-orientable surfaces.
method Dehn twist--crosscap slide presentations.
result Presentations for involutions on non-orientable surfaces of genera up to 5.
This paper proposes synthetic augmentation for nuclei image segmentation in medical pathology.
problem Rare and time-consuming labeling of tumor nuclei images for semantic segmentation.
method Label-to-image translation to generate synthetic images.
result Synthetic augmentation improves segmentation accuracy.
We present a new operation to be performed on elements in a Garside group, called cyclic sliding, which is introduced to replace the well known cycling and decycling operations. Cyclic sliding appears to be a more natural choice, simplifying the algorithms concerning conjugacy in Garside groups and having nicer theoret…
Novel time series forecasting method using sliding window signatures.
problem Challenges in forecasting nonlinear and delayed time series data.
method Ridge regression with signature features calculated on sliding windows.
result Signature features effectively encode temporal and nonlinear dependencies, leading to accurate forecasts.
Proposes a sliding window method for better portfolio trading.
problem Log-optimal portfolio problem with time-varying weights.
method Data-driven sliding window approach to solve log-optimal portfolio problem.
result Trading strategy outperforms classical log-optimal portfolio in cumulative returns.
Unified tensor model disentangles object appearance factors.
problem Representing hierarchical intrinsic and extrinsic causal factors of object appearance.
method Compositional hierarchical tensor factorization.
result Interpretable object representation robust to occlusion and reduced training data requirements.
Framework analyzes leaf vein architecture using deep learning and statistical methods.
problem Discards structural information in leaf venation studies.
method Integrates deep learning and statistical techniques to represent and analyze leaf vascular architecture.
result Identifies significant gene-environment interactions in leaf vascular architecture.
Paper simplifies proof of slide-equivalence in crown diagrams.
problem Proving slide-equivalence of crown diagrams.
method Diagrammatic approach to generalized shift moves.
result Slide-equivalence of vanishing cycles in crown diagrams.
Semantic boundary and edge detection aims at simultaneously detecting object edge pixels in images and assigning class labels to them. Systematic training of predictors for this task requires the labeling of edges in images which is a particularly tedious task. We propose a novel strategy for solving this task, when pi…
Optimizes sliding window approach for tracking Gaussian densities.
problem Improving tracking performance of Gaussian density estimation.
method Theoretical analysis of sliding window Gaussian Kernel Density Estimators.
result Empirical evidence shows improved tracking performance with optimal weight sequence.
Let Ng denote a closed nonorientable surface of genus g. For g≥2 the mapping class group M(Ng) is generated by Dehn twists and one crosscap slide (Y-homeomorphism) or by Dehn twists and a crosscap transposition. Margalit and Schleimer observed that Dehn twists have nontrivial roots. We gi…
Small bubbles sliding on a boundary maintain half-spherical shape.
problem Preserving the shape of small bubbles sliding on a boundary.
method Area-preserving Willmore flow, asymptotic analysis, convergence proof.
result The flow keeps a half-spherical shape for all times.
We give a combinatorial proof, using the hyperbolicity of the curve graphs, of the bounded geodesic image theorem of Masur and Minsky. Recently it has been shown that curve graphs are uniformly hyperbolic, thus a universal bound can be given for the diameter of the geodesic image. We also generalize the theorem for pro…
We show that reducible braids which are, in a Garside-theoretical sense, as simple as possible within their conjugacy class, are also as simple as possible in a geometric sense. More precisely, if a braid belongs to a certain subset of its conjugacy class which we call the stabilized set of sliding circuits, and if it …