arXiv research

Tract-specific diffusion measures, as derived from brain diffusion MRI, have been linked to white matter tract structural integrity and neurodegeneration. As a consequence, there is a large interest in the automatic segmentation of white matter tract in diffusion tensor MRI data. Methods based on the tractography are p…

Enhances geodesic fiber tracking in white matter using modified metrics and tensor data.

In-vivo examination of the physical connectivity of axonal projections through the white matter of the human brain is made possible by diffusion weighted magnetic resonance imaging (dMRI) Analysis of dMRI commonly considers derived scalar metrics such as fractional anisotrophy as proxies for "white matter integrity," a…

Paper proposes a new Autoencoder for robustly encoding white matter streamlines.

Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the length of each white matter fascicle, termed the local connectome. If communicat…

Geometric framework for aligning fiber tracts across subjects.

In this work, we present a comparison of a shallow and a deep learning architecture for the automated segmentation of white matter lesions in MR images of multiple sclerosis patients. In particular, we train and test both methods on early stage disease patients, to verify their performance in challenging conditions, mo…

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) that results in focal injury to the grey and white matter. The presence of white matter lesions biases morphometric analyses such as registration, individual longitudinal measurements and tissue segmentation for brain v…

Clustering is concerned with coherently grouping observations without any explicit concept of true groupings. Spectral graph clustering - clustering the vertices of a graph based on their spectral embedding - is commonly approached via K-means (or, more generally, Gaussian mixture model) clustering composed with either…

Tractograms are mathematical representations of the main paths of axons within the white matter of the brain, from diffusion MRI data. Such representations are in the form of polylines, called streamlines, and one streamline approximates the common path of tens of thousands of axons. The analysis of tractograms is a ta…

White matter hyperintensity (WMH) is commonly found in elder individuals and appears to be associated with brain diseases. U-net is a convolutional network that has been widely used for biomedical image segmentation. Recently, U-net has been successfully applied to WMH segmentation. Random initialization is usally used…

Deep learning ensemble improves Alzheimer vs. Mild Cognitive Impairment diagnosis.

To accurately analyze changes of anatomical structures in longitudinal imaging studies, consistent segmentation across multiple time-points is required. Existing solutions often involve independent registration and segmentation components. Registration between time-points is used either as a prior for segmentation in a…

Algorithms for Magnetic Resonance (MR) image reconstruction from undersampled measurements exploit prior information to compensate for missing k-space data. Deep learning (DL) provides a powerful framework for extracting such information from existing image datasets, through learning, and then using it for reconstructi…

There has been extensive research on developing defense techniques against adversarial attacks; however, they have been mainly designed for specific model families or application domains, therefore, they cannot be easily extended. Based on the design philosophy of ensemble of diverse weak defenses, we propose ATHENA---…

Diffusion-weighted magnetic resonance imaging (DWI) and fiber tractography are the only methods to measure the structure of the white matter in the living human brain. The diffusion signal has been modelled as the combined contribution from many individual fascicles of nerve fibers passing through each location in the …

The choice of model class is fundamental in statistical learning and system identification, no matter whether the class is derived from physical principles or is a generic black-box. We develop a method to evaluate the specified model class by assessing its capability of reproducing data that is similar to the observed…

Supervised learning algorithms trained on medical images will often fail to generalize across changes in acquisition parameters. Recent work in domain adaptation addresses this challenge and successfully leverages labeled data in a source domain to perform well on an unlabeled target domain. Inspired by recent work in …

Counting is a fundamental task in biomedical imaging and count is an important biomarker in a number of conditions. Estimating the uncertainty in the measurement is thus vital to making definite, informed conclusions. In this paper, we first compare a range of existing methods to perform counting in medical imaging and…

Diffusion-weighted MR imaging (DWI) is the only method we currently have to measure connections between different parts of the human brain in vivo. To elucidate the structure of these connections, algorithms for tracking bundles of axonal fibers through the subcortical white matter rely on local estimates of the fiber …

Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further establish the credentials of "brain-predicted age" as a biomarker of individual differe…

Watermarking of deep neural networks (DNN) can enable their tracing once released by a data owner. In this paper, we generalize white-box watermarking algorithms for DNNs, where the data owner needs white-box access to the model to extract the watermark. White-box watermarking algorithms have the advantage that they do…

Study analyzes correlation structure in two-factor Hull-White model for XVA calculations.

Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a result of their high accuracy in different segmentation problems. We present a n…

Local semi-supervised method improves brain tissue classification in child MRI.

Diffusion magnetic resonance imaging (dMRI) and tractography provide means to study the anatomical structures within the white matter of the brain. When studying tractography data across subjects, it is usually necessary to align, i.e. to register, tractographies together. This registration step is most often performed…

No minimal charts with exactly seven white vertices found.

We explore a model of dark matter called wave dark matter (also known as scalar field dark matter and boson stars) which has recently been motivated by a new geometric perspective by Bray. Wave dark matter describes dark matter as a scalar field which satisfies the Einstein-Klein-Gordon equations. These equations rely …

This paper introduces a fast, general method for dictionary-free parameter estimation in quantitative magnetic resonance imaging (QMRI) via regression with kernels (PERK). PERK first uses prior distributions and the nonlinear MR signal model to simulate many parameter-measurement pairs. Inspired by machine learning, PE…

Black women and white men have the highest income disparity in the U.S.

The evaluation of white matter lesion progression is an important biomarker in the follow-up of MS patients and plays a crucial role when deciding the course of treatment. Current automated lesion segmentation algorithms are susceptible to variability in image characteristics related to MRI scanner or protocol differen…

This paper analyzes crypto white papers under MiCAR, highlighting NLP's role.

Study how past eon's matter affects present eon in Penrose's cyclic cosmology.

We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and cerebrospinal fluid, in addition to tumorous tissue. Regarding our first innovati…

Neural net reconstructs dark matter density from halo velocities.

We give a method to construct Calabi-Yau metrics on G-invariant vector bundles over Kahler coset spaces G/H using supersymmetric nonlinear realizations with matter coupling. As a concrete example we discuss the CP^N model coupled with matter. The canonical line bundle is reproduced by the singlet matter and the cotange…

ODS improves adversarial attacks by maximizing output diversity.

Diffusion magnetic resonance imaging (dMRI) data allow to reconstruct the 3D pathways of axons within the white matter of the brain as a tractography. The analysis of tractographies has drawn attention from the machine learning and pattern recognition communities providing novel challenges such as finding an appropriat…

We present a new approach to the optimal portfolio problem for an insider with logarithmic utility. Our method is based on white noise theory, stochastic forward integrals, Hida-Malliavin calculus and the Donsker delta function.

Study investigates Einstein flow stability and convergence with matter sources.

Throughout the literature on the charged Riemannian Penrose inequality, it is generally assumed that there is no charged matter present; that is, the electric field is divergence-free. The aim of this article is to clarify when the charged Riemannian Penrose inequality holds in the presence of charged matter, and when …

This paper studies business cycle patterns in UK sectoral output. It analyzes the distinction between white noise processes and their non-white noise counterparts in the frequency domain and further examines the associated features and patterns for the process where white noise conditions are violated. The characterist…

Deep neural networks are susceptible to various inference attacks as they remember information about their training data. We design white-box inference attacks to perform a comprehensive privacy analysis of deep learning models. We measure the privacy leakage through parameters of fully trained models as well as the pa…

We investigate minimal charts with loops, a simple closed curve consisting of edges of label $m$ containing exactly one white vertex. We shall show that there does not exist any loop in a minimal chart with exactly seven white vertices in this paper.

QC methods improve reliability of machine learning-based image segmentation.

Study 6D localized matter spectrum on singular Calabi-Yau 3-folds.

Paper proves stronger Penrose inequality with matter density.

New formulas for barrier options in stochastic volatility models with nonzero correlation.