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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,742 papers · 148 categories

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48 results for treatment guidelines

Paper derives policy rules from observational data for hepatitis C treatment.

problem Improving treatment guidelines for HIV/HCV co-infected patients.
method Weighted K-means algorithm for estimating CATEs, decision tree implementation.
result Identifies a subgroup with high spontaneous HCV clearance rate.

Improving cancer treatment decisions requires considering causal effects, not just model accuracy.

problem Cancer outcome prediction models may cause harm when used for treatment decisions.
method Explains the importance of considering causal effects in model validation and provides guidelines.
result Building and validating models that are useful for decision making requires considering causal effects.

The paper learns personalized treatment rules from observational data.

problem Developing effective treatment policies for individual patients.
method Contextual bandit approach to minimize expected risk of treatment policies.
result The proposed method outperforms physicians and baseline approaches in IV and VP administration.

Unified survey of treatment effect heterogeneity and uplift modeling methods.

problem Estimating heterogeneous treatment effects and uplift modeling.
method Unified survey of treatment effect heterogeneity and uplift modeling approaches.
result Unified notations for comparing methods and applications in personalized marketing, medicine, and social studies.

New method for finding optimal treatment regimes in medical settings with time-varying unobserved factors.

problem Finding optimal treatment regimes in medical settings with time-varying unobserved factors.
method Extend Dynamic Treatment Regimes (DTRs) to Ambiguous Dynamic Treatment Regimes (ADTRs), connect to Ambiguous Partially Observable Mark Decision Processes (APOMDPs), and develop Reinforcement Learning methods.
result Established theoretical results for learning methods, including consistency and asymptotic normality.

A new method improves treatment effect inferences in RCTs by adjusting for covariates and heteroskedasticity.

problem Improving treatment effect inferences in RCTs with efficient and powerful methods.
method Weighted Prognostic Covariate Adjustment Method (Weighted PROCOVA) for heteroskedasticity.
result The method reduces variance, maintains Type I error rate, and increases test power for treatment effect.

Study uses LLMs to create personalized treatment plans for rare gynecological tumors.

problem Suboptimal management and poor prognosis due to low incidence and heterogeneity of rare gynecological tumors.
method Developed a digital twin system using LLMs to integrate clinical and biomarker data.
result LLM-enabled digital twins efficiently model individual patient trajectories and identify potential treatment options.

The paper integrates AI and expert knowledge to optimize radiotherapy decisions.

problem Optimizing radiation dose planning considering patient-specific information.
method Integrating Gaussian process models with deep neural networks to quantify uncertainty.
result Improves AI model performance and guides clinical decision making.

Current advances in research, development and application of artificial intelligence (AI) systems have yielded a far-reaching discourse on AI ethics. In consequence, a number of ethics guidelines have been released in recent years. These guidelines comprise normative principles and recommendations aimed to harness the …

2019-02-28abs ↗pdf ↗

Framework for applying GPs to real-world data with scalability guidelines.

problem Deployment of Gaussian Processes (GPs) is hindered by computational costs and lack of guidelines.
method Proposed a framework for identifying GP suitability and setting up robust models, formalizing decisions of experienced practitioners.
result More accurate results at test time for glacier elevation change case study.

Treatment recommendations within Clinical Practice Guidelines (CPGs) are largely based on findings from clinical trials and case studies, referred to here as research studies, that are often based on highly selective clinical populations, referred to here as study cohorts. When medical practitioners apply CPG recommend…

2019-07-09abs ↗pdf ↗

Deep learning clusters patient time-series data for better prognosis.

problem Clustering time-series data for patient phenotyping and prognosis.
method Deep predictive clustering with novel loss functions for future outcome distribution.
result Model achieves superior clustering performance and identifies meaningful patient subgroups.

Scale of data and scale of computation infrastructures together enable the current deep learning renaissance. However, training large-scale deep architectures demands both algorithmic improvement and careful system configuration. In this paper, we focus on employing the system approach to speed up large-scale training.…

2017-08-10abs ↗pdf ↗

Sherpa.ai framework combines federated learning and differential privacy for edge AI services.

problem Protecting data privacy in edge AI services.
method Holistic federated learning and differential privacy approach with methodological guidelines.
result Demonstrated through classification and regression use cases.

Deep neural networks (DNNs) have been proven to have many redundancies. Hence, many efforts have been made to compress DNNs. However, the existing model compression methods treat all the input samples equally while ignoring the fact that the difficulties of various input samples being correctly classified are different…

2018-07-04abs ↗pdf ↗

The study analyzes convergence rates for sparse pivotal estimators in high-dimensional regression.

problem Sparse pivotal estimation in high-dimensional regression problems.
method Theoretical analysis and comparison of non-smooth + non-smooth optimization problems, including smoothing techniques.
result Minimax sup-norm convergence rates for square-root Lasso-type estimators are derived.

State-of-the-art machine learning frameworks support a wide variety of design features to enable a flexible machine learning programming interface and to ease the programmability burden on machine learning developers. Identifying and using a performance-optimal setting in feature-rich frameworks, however, involves a no…

2019-08-13abs ↗pdf ↗

Electronic health records (EHR) data provide a cost and time-effective opportunity to conduct cohort studies of the effects of multiple time-point interventions in the diverse patient population found in real-world clinical settings. Because the computational cost of analyzing EHR data at daily (or more granular) scale…

2017-05-27abs ↗pdf ↗

This chapter introduces reproducibility in machine learning for medical imaging.

problem Lack of reproducibility in machine learning for medical imaging.
method Distinguishes and defines types of reproducibility, outlines requirements, and discusses utility.
result Discussion on benefits and a plea for a non-dogmatic approach to reproducibility.

A framework for causal classification using uplift and causal heterogeneity methods.

problem Predicting the effect of interventions on different individuals from data.
method Causal classification framework using off-the-shelf supervised methods.
result Framework works for causal classification and uplift modelling, competitive with other methods.

Survival analysis models predict economic convergence across Americas.

problem Analyzing GDP per capita trajectories and convergence across the Americas.
method Survival analysis, machine learning, economic interpretation.
result DeepSurv captures non-linear interactions in GDP per capita trajectories.

GraphITE estimates individual effects of graph-structured treatments.

problem Estimating individual effects of complex treatment structures.
method Graph neural networks and Hilbert-Schmidt Independence Criterion regularization.
result GraphITE outperforms baselines in estimating treatment effects for large numbers of treatments.

The paper analyzes SMOTE for imbalanced classification, providing theoretical bounds and guidelines.

problem The challenge of imbalanced classification problems, especially with minority classes.
method Theoretical analysis of SMOTE and related oversampling techniques for minority classes.
result Derives concentration and excess risk bounds for SMOTE and kernel-based classifiers.

Robust low-rank matrix estimation is a topic of increasing interest, with promising applications in a variety of fields, from computer vision to data mining and recommender systems. Recent theoretical results establish the ability of such data models to recover the true underlying low-rank matrix when a large portion o…

2011-09-28abs ↗pdf ↗

Proposes a new method to estimate continuous treatment policies and match treatments effectively.

problem Current methods struggle with continuous treatment policies and complex matching.
method Formulates treatment effectiveness as a parametrizable model, using deep learning for optimization.
result Significant improvement in treatment effectiveness and matching efficiency.

Framework generates personalized insulin treatment strategies using deep models.

problem Developing optimal personalized treatment strategies for diabetes patients.
method Combines deep generative time series models with decision theory.
result Demonstrated improved personalized insulin treatment strategies for diabetes patients.

The paper provides guidelines for choosing between SBI methods in complex biological models.

problem Choosing appropriate SBI methods for real-world biological data.
method Comprehensive guidelines and application to agent-based models.
result Statistical SBI methods outperform neural SBI methods with sufficient computational resources.

Unified theory explains two failure modes of deep transformers and provides initialisation guidelines.

problem Two failure modes (rank collapse and entropy collapse) of self-attention layers in deep transformers.
method Analytical theory of signal propagation through deep transformers, using the Random Energy Model analogy.
result Simple algorithm to compute trainability diagrams for correct initialisation hyper-parameters.

Develops deep jump learning for continuous treatment OPE.

problem Estimating mean outcomes under new treatment rules using historical data from different rules.
method Adaptive deep discretization of continuous treatment space using deep learning and multi-scale change point detection.
result Validated method through theoretical results, simulations, and real application to Warfarin Dosing.

Method controls treatment risk in learning beneficial allocations.

problem Learning beneficial treatment allocations with risk control in precision medicine.
method Proposes a certifiable learning method that controls treatment risk with finite samples in the partially identified setting.
result Illustrates method using both simulated and real data.