End-to-end CAD system for thyroid nodule classification using multimodal data and expert guidance.
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3D Axial-Attention improves lung nodule classification accuracy.
Machine learning approaches hold great potential for the automated detection of lung nodules in chest radiographs, but training the algorithms requires vary large amounts of manually annotated images, which are difficult to obtain. Weak labels indicating whether a radiograph is likely to contain pulmonary nodules are t…
Lung cancer is the leading cause of cancer-related death worldwide. Early diagnosis of pulmonary nodules in Computed Tomography (CT) chest scans provides an opportunity for designing effective treatment and making financial and care plans. In this paper, we consider the problem of diagnostic classification between beni…
Different types of Convolutional Neural Networks (CNNs) have been applied to detect cancerous lung nodules from computed tomography (CT) scans. However, the size of a nodule is very diverse and can range anywhere between 3 and 30 millimeters. The high variation of nodule sizes makes classifying them a difficult and cha…
Computed tomography (CT) examinations are commonly used to predict lung nodule malignancy in patients, which are shown to improve noninvasive early diagnosis of lung cancer. It remains challenging for computational approaches to achieve performance comparable to experienced radiologists. Here we present NoduleX, a syst…
One of the problems on the way to successful implementation of neural networks is the quality of annotation. For instance, different annotators can annotate images in a different way and very often their decisions do not match exactly and in extreme cases are even mutually exclusive which results in noisy annotations a…
Cancer is still one of the most devastating diseases of our time. One way of automatically classifying tumor samples is by analyzing its derived molecular information (i.e., its genes expression signatures). In this work, we aim to distinguish three different types of cancer: thyroid, skin, and stomach. For that, we co…
Purpose: Lung nodules have very diverse shapes and sizes, which makes classifying them as benign/malignant a challenging problem. In this paper, we propose a novel method to predict the malignancy of nodules that have the capability to analyze the shape and size of a nodule using a global feature extractor, as well as …
Accurate quantification of pulmonary nodules can greatly assist the early diagnosis of lung cancer, which can enhance patient survival possibilities. A number of nodule segmentation techniques have been proposed, however, all of the existing techniques rely on radiologist 3-D volume of interest (VOI) input or use the c…
U-Det improves lung nodule segmentation in CT images.
System converts 3D lung nodule images into embeddings for retrieval.
We explore several oversampling techniques for an imbalanced multi-label classification problem, a setting often encountered when developing models for Computer-Aided Diagnosis (CADx) systems. While most CADx systems aim to optimize classifiers for overall accuracy without considering the relative distribution of each …
Paper reduces false positives in lung nodule detection using deep learning on point clouds.
One of the challenges of using machine learning techniques with medical data is the frequent dearth of source image data on which to train. A representative example is automated lung cancer diagnosis, where nodule images need to be classified as suspicious or benign. In this work we propose an automatic synthetic lung …
Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a fast and robust computer aided system. In this work, we propose an end-to-end tra…
The state of the art lung nodule detection studies rely on computationally expensive multi-stage frameworks to detect nodules from CT scans. To address this computational challenge and provide better performance, in this paper we propose S4ND, a new deep learning based method for lung nodule detection. Our approach use…
Study uses multi-task Bayesian optimization to speed up SVM hyperparameter tuning for nodules diagnosis.
Convolutional Neural Networks (CNNs) require a large amount of annotated data to learn from, which is often difficult to obtain in the medical domain. In this paper we show that the sample complexity of CNNs can be significantly improved by using 3D roto-translation group convolutions (G-Convs) instead of the more conv…
Computed tomography (CT) generates a stack of cross-sectional images covering a region of the body. The visual assessment of these images for the identification of potential abnormalities is a challenging and time consuming task due to the large amount of information that needs to be processed. In this article we propo…
CovRegRF estimates covariance matrix from covariates using random forests.
Motivated by the problem of computer-aided detection (CAD) of pulmonary nodules, we introduce methods to propagate and fuse uncertainty information in a multi-stage Bayesian convolutional neural network (CNN) architecture. The question we seek to answer is "can we take advantage of the model uncertainty provided by one…
Generating large quantities of quality labeled data in medical imaging is very time consuming and expensive. The performance of supervised algorithms for various tasks on imaging has improved drastically over the years, however the availability of data to train these algorithms have become one of the main bottlenecks f…
Computer aided diagnostic (CAD) system is crucial for modern med-ical imaging. But almost all CAD systems operate on reconstructed images, which were optimized for radiologists. Computer vision can capture features that is subtle to human observers, so it is desirable to design a CAD system op-erating on the raw data. …
Machine learning applications in medical imaging are frequently limited by the lack of quality labeled data. In this paper, we explore the self training method, a form of semi-supervised learning, to address the labeling burden. By integrating reinforcement learning, we were able to expand the application of self train…
New method uses probabilistic independence to discover disease signatures from medical records.
Localization of chest pathologies in chest X-ray images is a challenging task because of their varying sizes and appearances. We propose a novel weakly supervised method to localize chest pathologies using class aware deep multiscale feature learning. Our method leverages intermediate feature maps from CNN layers at di…
In this paper, we investigate algorithms for anomaly detection. Previous anomaly detection methods focus on modeling the distribution of non-anomalous data provided during training. However, this does not necessarily ensure the correct detection of anomalous data. We propose a new Regularized Cycle Consistent Generativ…
The accurate estimation of predictive uncertainty carries importance in medical scenarios such as lung node segmentation. Unfortunately, most existing works on predictive uncertainty do not return calibrated uncertainty estimates, which could be used in practice. In this work we exploit multi-grader annotation variabil…
Proposes ConRad model for lung cancer classification using radiomics and interpretable machine learning.
Objective: Ultrasound elastography is gaining traction as an accessible and useful diagnostic tool for such things as cancer detection and differentiation and thyroid disease diagnostics. Unfortunately, state of the art shear wave imaging techniques, essential to promote this goal, are limited to high-end ultrasound ha…
We correct for sampling bias in training models to improve real-world performance.
In this paper, we present UNet++, a new, more powerful architecture for medical image segmentation. Our architecture is essentially a deeply-supervised encoder-decoder network where the encoder and decoder sub-networks are connected through a series of nested, dense skip pathways. The re-designed skip pathways aim at r…
Often the challenge associated with tasks like fraud and spam detection is the lack of all likely patterns needed to train suitable supervised learning models. This problem accentuates when the fraudulent patterns are not only scarce, they also change over time. Change in fraudulent pattern is because fraudsters contin…
Computer-Aided-Diagnosis (CADx) systems assist radiologists with identifying and classifying potentially malignant pulmonary nodules on chest CT scans using morphology and texture-based (radiomic) features. However, radiomic features are sensitive to differences in acquisitions due to variations in dose levels and slic…
Dual-stage sEMG classification improves gesture recognition accuracy.
A novel method for classification with rejection using ensemble of cost-sensitive classifiers.
The number of possible methods of generalizing binary classification to multi-class classification increases exponentially with the number of class labels. Often, the best method of doing so will be highly problem dependent. Here we present classification software in which the partitioning of multi-class classification…
Sequence classification is an important data mining task in many real world applications. Over the past few decades, many sequence classification methods have been proposed from different aspects. In particular, the pattern-based method is one of the most important and widely studied sequence classification methods in …
New NHCAs improve multi-category classification efficiency.
Classification outperforms regression in portfolio construction, yielding higher Sharpe ratios.
C-HMCNN(h) improves HMC classification by leveraging class hierarchy.
Advances few-shot classification by treating it as supervised learning and proposing new training techniques.
We study realizations of Lie algebras by vector fields. A correspondence between classification of transitive local realizations and classification of subalgebras is generalized to the case of regular local realizations. A reasonable classification problem for general realizations is rigorously formulated and an algori…
New approach improves classification guarantees by focusing on direction rather than regression risk.
Study selective classification with halfspaces, achieving error bounds under Gaussian distributions.
A new network-based high-level data classification method using betweenness centrality.
This thesis evaluates text-based vs audio-based classification of mental health interviews.