Forest-based methods have recently gained in popularity for non-parametric treatment effect estimation. Building on this line of work, we introduce causal survival forests, which can be used to estimate heterogeneous treatment effects in a survival and observational setting where outcomes may be right-censored. Our app…
The paper benchmarks OS with RCTs, accounting for right-censoring.
problem Benchmarking observational studies with experimental data under censoring.
method Two cases: independent and dependent censoring. Censoring-doubly-robust signal for CATE.
result Effectiveness of censoring-aware tests verified via experiments and real data.
New method estimates treatment effects over time for survival data, improving accuracy and smoothness.
problem Estimating treatment effects over time for survival data with left truncation and right censoring.
method surv-iTMLE, a targeted learning procedure for estimating conditional survival probabilities.
result surv-iTMLE outperforms existing methods in bias and smoothness of time-varying effect estimates.
DSL estimates heterogeneous treatment effects over time in survival settings.
problem Complicated by right censoring and time-varying treatment effects.
method Deep survival learner (DSL) for estimating CATEs over a clinically relevant time spectrum.
result DSL reveals heterogeneity in perioperative chemotherapy effects over time.
The paper develops deep learning models for personalized treatment rules in survival analysis.
problem Deriving optimal treatment rules for bivariate survival outcomes in randomized trials.
method Adaptive prediction-powered learning using deep neural networks and stochastic policies.
result Maximizes joint survival probability beyond fixed time points (t1,t2). New method for accurate uncertainty estimation in deep learning predictions.
problem Insufficient methods for assessing prediction uncertainty in deep learning.
method Valid non-parametric bootstrap method for deep neural networks.
result Accurate confidence intervals and simultaneous confidence bands for survival data.
Study evaluates ML methods for two-sample testing with right-censored data.
problem Evaluating ML methods for two-sample testing with right-censored data.
method Developed and compared several ML-based methods with classical tests.
result Proposed methods outperform classical tests in terms of statistical power.
New methods improve off-policy evaluation for survival outcomes with censoring.
problem Systematic underestimation of policy performance due to censoring bias in survival outcomes.
method Proposes IPCW-IPS and IPCW-DR to handle censoring bias in survival outcomes.
result The proposed methods are unbiased and achieve double robustness.
SurvivalBoost improves prediction of event times in competing risks scenarios.
problem Predicting event times in scenarios with multiple possible outcomes.
method Developed a strictly proper censoring-adjusted scoring rule for stochastic optimization of competing risks.
result SurvivalBoost outperforms 12 state-of-the-art models across various metrics.
Study improves risk evaluation timing with right-censored reporting delays.
problem Improving risk evaluation under short observation windows due to administrative censoring.
method Jointly models parametric hazards for event and reporting processes, uses Monte Carlo expectation-maximization algorithm, and proposes transfer-learning procedure.
result Improves accuracy of timely risk evaluation under administrative censoring.
Develops adaptive framework for estimating survival effects with censoring.
problem Estimating causal effects in survival data with censoring.
method Derives semiparametric efficiency bound, proposes efficiency-optimal allocation policy, and develops Adaptive Survival Estimator (ASE).
result ASE achieves asymptotic normality via martingale central limit theorem and demonstrates efficiency gains over uniform randomization.
We develop a novel algorithm to predict the occurrence of major abdominal surgery within 5 years following Crohn's disease diagnosis using a panel of 29 baseline covariates from the Swedish population registers. We model pseudo-observations based on the Aalen-Johansen estimator of the cause-specific cumulative incidenc…
Efficient oblique RSF method improves prediction and interpretability.
problem Limited computational efficiency and difficulty in interpreting oblique RSF ensembles.
method Newton-Raphson scoring for computational efficiency and negation importance for variable importance estimation.
result The method reduces computational overhead by 450 times and improves prediction accuracy.
Develops a TL framework for estimating RMST difference in clinical trials.
problem Estimating RMST difference in clinical trials with time-to-event outcomes.
method Targeted learning (TL) framework using pseudo-observations and copy reference (CR) approach for sensitivity analysis.
result Demonstrated the effectiveness of the TL framework using real data.
SurvFM-RMST converts survival outcomes into pseudo-observation targets for tabular models.
problem Right-censored follow-up prevents direct use of survival labels in tabular patient data.
method SurvFM-RMST framework that converts survival outcomes into jackknife pseudo-observation targets for restricted mean survival time.
result SurvFM-RMST accurately recovered restricted event-free time in simulations and outperformed naive targets in static datasets.
A new model avoids the PH assumption for right-censored survival data.
problem Inflexibility of Cox model when PH assumption fails.
method Deep partially linear transformation model (DPLTM) for right-censored data.
result The DPLTM avoids the curse of dimensionality and retains interpretability.
Research uses deep learning and copulas to predict multivariate survival data.
problem Handling right-censored and correlated multivariate survival data.
method Integrates deep learning, copula functions, and survival analysis. Uses copula-based activation functions to model nonlinear dependencies.
result Enhanced prediction accuracy for multivariate survival responses.
Paper estimates spectral risk measures for insurance data with truncated and censored data.
problem Estimating spectral risk measures for insurance data with left truncation and right censoring.
method Proposes a non-parametric estimator using product limit estimator and establishes asymptotic normality.
result Proposed estimator outperforms existing methods for small k and small sample sizes.
SurvHTE-Bench benchmarks HTE estimation in survival analysis with diverse datasets.
problem Challenges in estimating HTEs from right-censored survival data.
method Modular synthetic datasets, semi-synthetic datasets, and real-world datasets.
result First rigorous comparison of survival HTE methods under diverse conditions.
In this paper, we consider survival analysis with right-censored data which is a common situation in predictive maintenance and health field. We propose a model based on the estimation of two-parameter Weibull distribution conditionally to the features. To achieve this result, we describe a neural network architecture …
We develop a unified approach for classification and regression support vector machines for data subject to right censoring. We provide finite sample bounds on the generalization error of the algorithm, prove risk consistency for a wide class of probability measures, and study the associated learning rates. We apply th…
Proposes a new Q-learning method for survival outcomes in clinical trials.
problem Incomplete follow-up data and nonlinear covariate effects in clinical trials.
method Combines Buckley-James boosting with flexible base learners for estimating optimal treatment regimes.
result Improves treatment decision accuracy and stability in longitudinal clinical trials.
New model bridges pricing and reserving for insurance claims.
problem Incomplete claim data due to reporting and settlement delays.
method Develops an occurrence and development model to estimate both claims and premiums.
result Effective resolution of pricing and reserving inconsistencies.
Models for predicting the risk of cardiovascular events based on individual patient characteristics are important tools for managing patient care. Most current and commonly used risk prediction models have been built from carefully selected epidemiological cohorts. However, the homogeneity and limited size of such coho…
Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimising the interpretation of dynamic biological systems requires accurate and precise motion tracking as well as efficient representations of high-dimensional motion trajectories so that these can be use…
New method estimates optimal personalized treatment rules from mixed data sources.
problem Combining RCT and observational data for personalized treatment rules.
method Doubly robust estimator for value function, maximizing within pre-specified ITR class.
result Consistent and asymptotically normal optimal value estimator with N−1/3 rate of convergence. Method predicts RMST from censored data using pseudo-observations and super learner.
problem Estimating RMST from right-censored data.
method Ensemble algorithm combining pseudo-observations and super learner.
result Method performs well in simulations and real data applications.
Survival regression method improves log-likelihood scores.
problem Improper scoring rules in survival regression models.
method SurvivalMonotonic-net (SuMo-net) with monotonic neural networks.
result SuMo-net achieves state-of-the-art log-likelihood scores.
We propose a nonparametric test of independence, termed optHSIC, between a covariate and a right-censored lifetime. Because the presence of censoring creates a challenge in applying the standard permutation-based testing approaches, we use optimal transport to transform the censored dataset into an uncensored one, whil…
Bayesian optimization (BO) aims to minimize a given blackbox function using a model that is updated whenever new evidence about the function becomes available. Here, we address the problem of BO under partially right-censored response data, where in some evaluations we only obtain a lower bound on the function value. T…
SurvivalPFN simplifies survival analysis through amortized Bayesian inference.
problem Selecting appropriate survival analysis methods requires expertise and can be time-consuming.
method SurvivalPFN uses a prior-data fitted network for in-context Bayesian inference.
result SurvivalPFN achieves strong predictive performance across diverse datasets.
We introduce a general non-parametric independence test between right-censored survival times and covariates, which may be multivariate. Our test statistic has a dual interpretation, first in terms of the supremum of a potentially infinite collection of weight-indexed log-rank tests, with weight functions belonging to …
GCQRF predicts survival quantiles without linearity assumptions.
problem Survival analysis with right censoring and nonlinearity.
method Global Censored Quantile Random Forest (GCQRF) for complex relationships.
result GCQRF outperforms existing methods in predictive accuracy.
Develops a Bayesian method for causal inference with partly censored time-to-event data.
problem Estimating causal effects with unobserved confounders and measurement errors in partly censored time-to-event data.
method Semiparametric Bayesian instrumental variable analysis using a two-stage Dirichlet process mixture model.
result The proposed method outperforms competing methods in simulations and real-world data analysis.
MISTR improves HTE estimation in survival data with heavy censoring and instrumental variables.
problem Estimating HTE in survival data with censoring and unobserved confounders.
method MISTR uses recursively imputed survival trees to handle censoring and instrumental variables.
result MISTR outperforms existing methods under heavy censoring and instrumental variable settings.
Study benchmarks 19 survival models on 34 datasets, finding Cox model still best.
problem Quantitative comparison of survival models on low-dimensional data.
method Comprehensive benchmarking of 19 models on 34 datasets, tuning and evaluating using 6 metrics.
result Cox Proportional Hazards model remains best overall for low-dimensional, right-censored data.
Enhances survival analysis by separating population behavior from individual dynamics.
problem Improving the training and inference of survival analysis models for sparsely occurring events.
method Decouples survival analysis into an aggregated baseline hazard and independent survival scores.
result Achieves competitive performance and robust results without fine-tuning.
A new method prices time-to-event cash flows using survival analysis.
problem Pricing insurance investment portfolios with time-to-event cash flows.
method Discrete-time survival analysis framework, hazard rate estimators, asymptotic multivariate normality.
result Pricing model yields estimates closer to actual cash flows than non-random models.
In this paper we describe a novel implementation of adaboost for prediction of survival function. We take different variations of the algorithm and compare the algorithms based on system run time and root mean square error. Our construction includes right censoring data and competing risk data too. We take different da…
New method for discrete-time survival analysis with competing risks.
problem Discrete failure time data in survival analysis.
method Proposes a new estimation procedure for discrete-time survival analysis with competing events.
result Offers advantages over existing procedures and integrates regularized regression methods.
Develops a neural model to predict event occurrence and timing.
problem Standard event time models ignore the distinction between event occurrence probability and predicted time.
method Introduces a conditional event time model using a neural network with a binary stochastic layer.
result Shows superior event occurrence and timing predictions on various datasets.
Random survival forests (RSF) are a powerful method for risk prediction of right-censored outcomes in biomedical research. RSF use the log-rank split criterion to form an ensemble of survival trees. The most common approach to evaluate the prediction accuracy of a RSF model is Harrell's concordance index for survival d…
Deep learning improves quantile regression for censored survival data.
problem Predicting nonlinear patterns in censored survival data.
method Neural network with adjusted check function for inverse censoring distribution.
result Deep learning outperforms traditional quantile regression methods in prediction accuracy.
Paper proposes a novel SVM method for creating survival trees.
problem Creating non-linear survival trees for right-censored data.
method L2-regularized dipole splitting criteria with kernel methods.
result Non-linear splits using polynomial and Gaussian kernels show similar predictive power but often smaller tree sizes.
Test for quasi-independence in ordered time data.
problem Determining dependence beyond temporal ordering.
method Nonparametric statistical test considering infinite alternatives.
result Better power and computational efficiency compared to existing methods.
We consider the classic supervised learning problem, where a continuous non-negative random label Y (i.e. a random duration) is to be predicted based upon observing a random vector X valued in Rd with d≥1 by means of a regression rule with minimum least square error. In various applications, rangi…
BoXHED2.0 boosts survival analysis for complex data.
problem Survival analysis with time-dependent covariates.
method Tree-boosted hazard estimator, fully nonparametric, scalable.
result Scalable to parametric boosted survival models in speed.
The paper predicts survival functions using random survival trees and concordance maximization.
problem Predicting conditional survival functions in right-censored data.
method The approach combines regression strategies with random survival trees and maximizes concordance.
result The proposed weighted predictor outperforms the usual survival cobra in terms of concordance.