Simulates patient pathways to detect delayed rare disease diagnoses.
problem Delayed rare disease diagnoses in France, causing health system and patient harm.
method Probabilistic modelling of patient pathways to create an alert system.
result Alert system detects and refers wandering patients to CRMRs.
Improved ECG classification using multi-task learning.
problem Low frequency of rare diagnoses in ECGs.
method Developed a multi-task CNN to classify multiple diagnoses from 12-lead ECGs.
result Adding common classes improves performance on rarer classes.
Approach for modeling EHR data with rare features, improving prediction and interpretation.
problem Challenges in modeling rare binary features in EHR data.
method Tree-guided feature selection and logic aggregation for large-scale regression.
result Improved prediction and model interpretation of suicide risk in EHR data.
New method uses surrogate outcomes and single-record data to improve suicide risk modeling.
problem Lack of historical information in single-record patients hinders modeling rare medical events.
method Hybrid framework combining supervised and unsupervised learning to integrate concurrent and single-record data.
result Single-record data and concurrent diagnoses provide valuable information for improving suicide risk modeling.
In rare disease physician targeting, a major challenge is how to identify physicians who are treating diagnosed or underdiagnosed rare diseases patients. Rare diseases have extremely low incidence rate. For a specified rare disease, only a small number of patients are affected and a fractional of physicians are involve…
Paper proposes CNN for diagnosing rare muscular dystrophies from images.
problem Challenges in diagnosing rare diseases due to lack of data.
method Uses a Convolutional Neural Network (CNN) for patch-based classification of confocal microscopy images.
result CNN system identifies problematic areas and provides global patient evaluation.
Predict genetic inheritance patterns using hypergraphs and latent models.
problem Diagnosing inherited diseases requires identifying family genetic patterns.
method Represent family trees as hypergraphs, use latent state space models for causal inference.
result Allows for explainable predictions of patient genotypes based on relatives' phenotypes.
Cheap model diagnoses vocal disorders accurately.
problem Diagnosing vocal disorders without expensive equipment.
method Used Mel-Cepstrum vectors and Support Vector Machine.
result Accurately diagnosed three vocal disorders.
Machine learning improves detection of Brugada Syndrome from ECGs.
problem Detecting Brugada Syndrome (BrS) from ECGs is challenging due to limited diagnostic criteria.
method Pipeline that reads and processes scanned ECG images, uses LSTM classifier to diagnose.
result The proposed pipeline distinguishes between ECG types and diagnoses BrS with high accuracy.
Predicting diagnoses from Electronic Health Records (EHRs) is an important medical application of multi-label learning. We propose a convolutional residual model for multi-label classification from doctor notes in EHR data. A given patient may have multiple diagnoses, and therefore multi-label learning is required. We …
New diagnostic tool for assessing approximate Bayesian inference.
problem Assessing the trustworthiness of approximate Bayesian inference.
method Reframe the problem in terms of incompatible conditional distributions and use Gibbs priors.
result The diagnostic tool can discover the inductive bias in various Bayesian models and approximations.
Models extract relevant EHR snippets to aid radiologists in diagnosis.
problem Difficulty in identifying relevant patient record information for diagnosis.
method Distantly supervised transformer-based neural model for extractive summarization.
result Models yield better extractive summaries than unsupervised approaches.
Flow cytometry is often used to characterize the malignant cells in leukemia and lymphoma patients, traced to the level of the individual cell. Typically, flow cytometric data analysis is performed through a series of 2-dimensional projections onto the axes of the data set. Through the years, clinicians have determined…
Smartphone app diagnoses pulmonary diseases from chest X-rays.
problem Scarcity of training data and class imbalance issues.
method Data Augmentation Generative Adversarial Network (DAGAN) and Convolutional Siamese Network with attention mechanism.
result Achieved 99.30% and 98.40% testing accuracy on Binary/Multiclass scenarios.
Paper presents a method to diagnose schizophrenia using fMRI dynamics from healthy controls.
problem Early diagnosis of mental disorders like schizophrenia using fMRI.
method Self-supervised pre-training on fMRI dynamics of healthy controls for transfer learning.
result Effective classification of schizophrenia using fMRI dynamics with small datasets.
The study diagnoses fairness issues in healthcare models under distribution shifts.
problem Understanding and diagnosing fairness changes in machine learning models under distribution shifts in healthcare.
method Causal framing and conditional independence tests to characterize distribution shifts.
result Knowledge of distribution shifts helps diagnose fairness transfer failures, including complex cases.
SHIFT framework identifies subgroups with large ML model performance decay.
problem Large model performance decay in subgroups when deployed.
method Subgroup-scanning Hierarchical Inference Framework (SHIFT) for performance drift.
result SHIFT identifies interpretable subgroups with large performance decay and suggests targeted actions to mitigate it.
Machine learning (ML) techniques such as (deep) artificial neural networks (DNN) are solving very successfully a plethora of tasks and provide new predictive models for complex physical, chemical, biological and social systems. However, in most cases this comes with the disadvantage of acting as a black box, rarely pro…
Categorical Co-Frequency Analysis clusters diagnoses to predict hospital readmissions.
problem Predicting patients' risk of 30-day hospital readmission.
method Categorical Co-Frequency Analysis (CoFA) measures diagnosis similarity using random forests.
result Identified three groups of diagnoses with varying readmission risk.
It is common in modern prediction problems for many predictor variables to be counts of rarely occurring events. This leads to design matrices in which many columns are highly sparse. The challenge posed by such "rare features" has received little attention despite its prevalence in diverse areas, ranging from natural …
Paper uses AI to improve medical diagnosis accuracy.
problem Improving accuracy of medical diagnoses.
method Heuristic frequentist and Bayesian approaches applied to a nationwide dataset.
result Algorithm outperforms human doctors in detecting abnormal births.
Deep learning boosts rare disease detection from medical claims.
problem Improving diagnosis and treatment of rare diseases.
method Generative adversarial networks (GANs) and recurrent neural networks for sequence modeling.
result Accurate prediction with 0.56 PR-AUC, outperforming benchmarks.
Paper uses GANs for efficient rare disease detection.
problem Efficient detection of rare diseases with limited labeled data.
method Semi-supervised learning with GANs.
result Best precision-recall scores compared to baseline techniques.
BADAC combines Bayesian methods for anomaly detection and classification.
problem Statistical uncertainties in machine learning algorithms, especially for anomaly detection.
method Unified hierarchical Bayesian framework that marginalizes over unknown data values.
result BADAC outperforms standard algorithms in classification and anomaly detection with uncertainties.
Deep learning methods exhibit promising performance for predictive modeling in healthcare, but two important challenges remain: -Data insufficiency:Often in healthcare predictive modeling, the sample size is insufficient for deep learning methods to achieve satisfactory results. -Interpretation:The representations lear…
Generative model simulates rare events for better decision making.
problem Rare events impact decision making but are hard to sample.
method Normalizing Flow coupled with Importance Sampling.
result Accurate estimation of rare events improves decision outcomes.
New algorithm detects rare categories with few labels.
problem Detecting rare categories with limited labeled data.
method Dimension-driven statistics and kappa-profile.
result Algorithm performs well on separable and non-separable classes.
AI boosts study of rare weather extremes with lower costs.
problem Difficulty in studying rare weather events due to limited data and models.
method Coupling AI forecasts with physics models using rare-event algorithms.
result Efficiently characterizes very rare events like once-per-millennium heatwaves.
proxymate diagnoses and corrects proxy estimates for reliable inference.
problem Systematic bias in proxy estimates can lead to invalid inference on primary outcomes.
method Four-level framework for proxy validation and adjustment, including diagnostic checks and targeted corrections.
result Facilitated quick decision making on thousands of experiments at Meta.
Develops a method to estimate rare-event probabilities under distributional uncertainty.
problem Distributional uncertainty limits the effectiveness of rare-event simulation techniques.
method Wasserstein distributionally robust rare-event simulation (DRIS) framework.
result DRIS achieves vanishing relative error in estimating rare-event probabilities.
RaRecognize learns to recognize rare classes in a stream of data.
problem Learning to recognize rare classes in a continuous stream of data.
method Estimates a general decision boundary, learns individual rare subclasses, flags new subclasses.
result RaRecognize outperforms state-of-the-art baselines on real-world datasets.
Reduces false positives in classifying rare online platforms.
problem Challenges in accurately identifying rare online platforms with ML.
method Calibrated probabilities and ensembles to reduce bias.
result Significantly reduces false positives in rare event detection.
This paper evaluates data enrichment techniques for rare event detection in manufacturing.
problem Rare events in manufacturing lead to unplanned downtime and high energy consumption.
method Time series data augmentation, sampling, and imputation techniques combined with supervised machine learning.
result Data enrichment enhances rare failure event detection and prediction by up to 48%.
Enhanced diffusion sampling improves rare event sampling in biomolecular simulations.
problem Efficiently sampling rare transition events in biomolecular systems.
method Quantitative steering protocols to generate biased ensembles and exact reweighting.
result Fast, accurate, and scalable estimation of equilibrium properties.
Enhanced diffusion sampling tackles rare event sampling in biomolecular simulations.
problem Efficiently sampling rare transition events in biomolecular simulations.
method Quantitative steering protocols to generate biased ensembles, followed by exact reweighting.
result Fast, accurate, and scalable estimation of equilibrium properties for folding free energies.
Proposes a method to ensure accurate estimation of rare events in AI systems.
problem Lack of efficiency guarantees in black-box systems for rare-event simulation.
method Integrates deep learning with importance sampling to create a statistically guaranteed estimator.
result Demonstrates effective estimation of rare-event probabilities in AI systems.
Framework harmonizes EHR data across institutions for better analysis.
problem Heterogeneity of medical codes and terminologies hinder EHR data analysis.
method MASH (Multi-source Automated Structured Hierarchy) uses neural optimal transport and learned hyperbolic embeddings to align and structure EHR data.
result MASH generates interpretable hierarchical graphs for unstructured local laboratory codes.
WEST uses EHRs and expert cases to improve rare disease phenotyping.
problem Limited labeled data for rare diseases.
method Weakly supervised transformer model trained on probabilistic silver-standard labels.
result WEST outperforms existing methods in phenotype classification and subphenotyping.
Inflated neural networks improve IPMN diagnosis from MRI scans.
problem Challenges in diagnosing IPMN from limited annotated data and 3D volumetric MRI.
method Developed two novel inflated deep network architectures, InceptINN and DenseINN, trained on ImageNet.
result Absolute improvement of 8.76% in accuracy for diagnosing IPMN.
This research examines rare spurious correlations in neural networks and their impact on accuracy and privacy.
problem Rare spurious correlations in neural networks and their privacy risks.
method Introducing spurious patterns correlated with a fixed class to a few training examples, analyzing ℓ2 regularization and Gaussian noise. result Rare spurious correlations can significantly impact neural network accuracy and privacy, and specific mitigation methods can be effective.
This paper studies the trade-off between model accuracy and coverage for diagnosis models used by patients.
problem Balancing accuracy and coverage in diagnosis models for patient use.
method Learned diagnosis models with varying coverage from EHR data.
result A 1% drop in top-3 accuracy for every 10 diseases added to the coverage.
Markov chain Monte Carlo (MCMC) algorithms for hidden Markov models often rely on the forward-backward sampler. This makes them computationally slow as the length of the time series increases, motivating the development of sub-sampling-based approaches. These approximate the full posterior by using small random subsequ…
Paper proposes using MC-dropout to detect and diagnose incipient faults in buildings.
problem Lack of labeled incipient fault data in buildings.
method Proposes using Monte Carlo dropout (MC-dropout) to enhance deep neural networks for fault detection.
result Demonstrates effectiveness of MC-dropout in indicating likely incipient fault types.
Automated suggestions help train technicians diagnose incidents faster.
problem Manual and time-consuming incident diagnosis by train maintenance technicians.
method Developed and deployed a learning machine to suggest diagnostics to technicians.
result The model refines its accuracy through feedback from experts and uses feature engineering.
Model predicts travel time under rare conditions using a vector-space model.
problem Predicting travel time under rare temporal conditions (e.g., holidays, school vacations) is challenging due to limited historical data and other temporal changes.
method Presented a vector-space model for encoding rare temporal conditions, allowing coherent representation learning across different conditions.
result Increased performance for travel time prediction over different baselines when using the vector-space encoding for representing the temporal setting.
Deep CNNs struggle with rare taxa; one-class classifiers help identify them.
problem Efficiently identifying rare benthic macroinvertebrates in insect monitoring.
method Combining deep CNNs with one-class classifiers to identify rare taxa.
result The proposed approach can improve rare species identification, supporting automation.
Capsule networks detect and diagnose adversarial images better than CNNs.
problem Detecting and diagnosing adversarial images in neural networks.
method Class-conditional capsule reconstruction and reconstructive attack.
result Capsule networks outperform CNNs in detecting and diagnosing adversarial images.
Detects and mitigates rare subclasses in deep neural networks.
problem Underrepresented classes in training datasets reduce classifier performance.
method Commonality metric for detection, methods for reducing impact during training and exploitation.
result Models compensate for rare subclasses, improving performance and runtime identification.