Proposes a framework for automated radiation therapy treatment planning with uncertainty quantification.
problem Quantifying uncertainties in dose-related quantities for automated treatment planning.
method Three-step pipeline: feature extraction, dose statistic prediction, and dose mimicking.
result Probabilistic treatment plans agree better with clinical counterparts than non-probabilistic ones.
Generative adversarial networks improve radiation therapy planning.
problem Creating optimal radiation therapy plans.
method Using a GAN to predict 3D dose distributions directly.
result Significantly outperforms previous methods in clinical satisfaction and metrics.
PT-WGAN reduces PET image noise without losing details.
problem Low-dose PET images suffer from noise and artifacts.
method Parameter-transferred Wasserstein GAN for denoising.
result PT-WGAN outperforms state-of-the-art methods in denoising.
Proposes a method to improve low-dose coronary CT angiography images.
problem Low-dose CT images are degraded due to reduced radiation dose.
method Cycle-consistent adversarial denoising network for semi-supervised learning.
result Significant reduction in noise with preserved texture and edges.
This paper combines deep learning with medical imaging models to improve reconstruction speed and reduce radiation.
problem Medical imaging issues like slow MRI, radiation injury in CT and PET.
method Combining deep learning with model-based reconstruction.
result Improves reconstruction speed and reduces radiation in medical imaging.
New method reduces radiation dose in CT scans while improving image quality.
problem Reducing radiation dose in CT scans while maintaining image quality.
method Combines PWLS and ℓ1 prior with learned sparsifying transform and ADMM algorithm.
result Improves image quality compared to existing methods for sparse-view CT.
Deep learning improves ROI reconstruction in low-dose CT.
problem Severe cupping artifacts in standard analytic reconstruction.
method Proposes a deep learning architecture to remove null space signals from FBP reconstruction.
result Near-perfect reconstruction with 7-10 dB improvement in PSNR.
The paper integrates AI and expert knowledge to optimize radiotherapy decisions.
problem Optimizing radiation dose planning considering patient-specific information.
method Integrating Gaussian process models with deep neural networks to quantify uncertainty.
result Improves AI model performance and guides clinical decision making.
The development of computed tomography (CT) image reconstruction methods that significantly reduce patient radiation exposure while maintaining high image quality is an important area of research in low-dose CT (LDCT) imaging. We propose a new penalized weighted least squares (PWLS) reconstruction method that exploits …
DEER network improves few-view breast CT image reconstruction efficiency and quality.
problem Efficient and high-quality few-view breast CT image reconstruction.
method Deep Efficient End-to-end Reconstruction (DEER) network with low model complexity.
result DEER network achieves competitive image quality with significantly fewer parameters compared to state-of-the-art methods.
New neural network reduces CT radiation, works for any ROI size.
problem CT ROI reconstruction suffers from cupping artifacts and high computation.
method Two neural networks: one learns ROI-specific artifacts, the other learns DBP inversion.
result New network outperforms existing methods for any ROI size.
Kernel method optimizes personalized dose rules for patients.
problem Finding optimal individualized dose rules for patients.
method Kernel assisted learning method for estimating optimal dose rules.
result The method identifies the optimal individualized dose rule and produces favorable outcomes.
Shared Keyboard design improves phase I clinical trials by borrowing information across doses.
problem Interim decisions based on current dose data may overlook signals from neighboring doses.
method Bayesian model-assisted design using Beta kernel process with kernel-weighted pseudo-counts.
result Significant improvements in identifying maximum tolerated dose and safety.
Novel algorithms improve warfarin dose prediction accuracy.
problem Challenges in estimating warfarin dose due to narrow therapeutic index and individual variability.
method Stacked generalization frameworks combining different machine learning algorithms.
result Stacked algorithms outperform the IWPC MLR algorithm, especially in subgroups.
New method estimates optimal dose intervals for personalized treatment.
problem Learning optimal dose intervals from observational data.
method Probability dose interval (PDI) method using DC algorithm.
result Consistent policy with risk converging to best-in-class at root-n rate.
Study uses Thompson Sampling to find optimal drug dosages in clinical trials.
problem Finding the best drug dosage in early-stage clinical trials.
method Adopted Thompson Sampling for dose-finding clinical trials, considering different monotonicity assumptions.
result Thompson Sampling variants outperform existing methods in various dose-finding scenarios.
A model predicts which patients can safely use a warfarin dosing algorithm.
problem Determining the optimal initial dose for warfarin patients.
method Support Vector Machines with a polynomial kernel function.
result The model increases dosing accuracy by 15% in RMSE and 17% in MAE.
Deep learning estimates dose voxel kernels from CT data for personalized dosimetry.
problem Accurate estimation of absorbed dose in personalized radionuclide therapy.
method Combining deep learning with CT data to approximate dose voxel kernels from density kernels.
result Deep learning achieved an intersection-over-union score of 0.86 and mean squared error of 1.24×10−4 on real patient data.
Proposes a method for generating prediction intervals in dose-response models using conformal prediction.
problem Uncertainty quantification in continuous treatments for personalized healthcare decisions.
method Causal dose-response problem framed as covariate shift, using weighted conformal prediction with propensity estimation and kernel functions.
result Demonstrates the significance of covariate shift assumptions for robust prediction intervals.
A spacetime denotes a pure radiation field if its energy momentum tensor represents a situation in which all the energy is transported in one direction with the speed of light. In 1989, Wils and later in 1997 Ludwig and Edgar studied the physical properties of pure radiation metrics, which are conformally related to a …
A new cycleGAN architecture reduces memory and parameter requirements for low-dose CT denoising.
problem Efficient unsupervised low-dose CT denoising with minimal memory and parameter usage.
method Single switchable generator using AdaIN layers for efficient training and inference.
result The proposed method outperforms previous cycleGAN approaches with half the parameters.
SEEDA optimizes dose allocation in clinical trials to balance efficacy and safety.
problem Complex relationships between efficacy and toxicity in new drug trials.
method Adaptive clinical trial methodology that maximizes cumulative efficacy while ensuring safety constraints.
result SEEDA outperforms existing methods in finding optimal doses with higher success rates and fewer patients.
A novel dose-finding design for cancer clinical trials using level set estimation.
problem Finding the maximum tolerated dose (MTD) in phase I cancer clinical trials.
method Proposes a novel dose-finding design based on level set estimation (LSE) to determine the next dose.
result The proposed LSE design achieves higher accuracy in estimating the MTD and lower risk of overdosing compared to existing designs.
New method estimates individual dose-response curves for any number of treatments.
problem Estimating individual dose-response curves for varied exposures.
method Neural network approach for learning counterfactual representations.
result Set a new state-of-the-art in estimating individual dose-response curves.
A ML-based method reconstructs 3D organ doses from 2D radiographs for pediatric abdominal radiotherapy.
problem Reconstructing detailed 3D dose distributions for childhood cancer survivors using limited 2D radiographs.
method Surrogate-free ML approach using 142 abdominal planning CTs, 300 artificial plans, and evolutionary algorithm.
result Accurate 3D dose reconstructions with MAEs ≤ 1.7 Gy for edge organs, validated on independent dataset.
New deep learning methods improve CT image quality from few projections.
problem Sparse-view CT images suffer from streaking artifacts due to limited projections.
method Inspired by deep convolutional framelets, propose new U-Net variants that satisfy the frame condition.
result New U-Net variants provide better reconstruction performance for sparse-view CT.
The study compares statistical post-processing methods for solar radiation forecasts.
problem Improving accuracy and uncertainty quantification of solar radiation forecasts.
method Statistical post-processing techniques using relationships between meteorological variables and solar radiation.
result Quantile regression and generalized random forests generally perform best in probabilistic forecasts.
New methods use RL and DA to improve dosing precision and reduce side effects.
problem Improving precision and safety of anticancer drug dosing.
method Bayesian data assimilation and reinforcement learning.
result Significantly reduces incidence of severe side effects.
Improved low-dose CT images with deep learning and framelet denoising.
problem Low-dose X-ray CT images often lack texture and detail.
method Proposed a wavelet residual network combining deep learning and framelet denoising.
result Significantly improved performance in preserving image detail.
The geometrical structures (in the sense of E. Cartan) are analyzed which underlie the gravitational radiation phenomenon. Among the results are : - the introduction of the adapted frame bundle to a congruence of isotropic hypersurfaces in a Lorentzian manifold, - the description of the reduced frame bundle which admit…
This study uses bandit algorithms to predict Warfarin dosages more accurately.
problem Determining the correct initial Warfarin dosage is challenging due to patient variability and adverse effects.
method Developed and evaluated linear bandit algorithms on real data from PharmGKB.
result Proposed algorithms outperformed fixed-dose and clinical algorithms.
New method segments brain tumors and organs-at-risk for radiation therapy.
problem Automating segmentation of brain tumors and organs-at-risk in radiation therapy planning.
method Combines contrast-adaptive generative model and spatial regularization model.
result Tumor segmentation accuracy comparable to state-of-the-art methods.
BCD-Net improves low-dose CT image reconstruction.
problem Challenges in obtaining accurate low-dose CT images.
method Modified iterative regression CNN, BCD-Net, with faster numerical solvers.
result BCD-Net achieves better image quality and generalization than state-of-the-art methods.
Proposes a new method to measure and avoid harm in machine learning decisions.
problem Measuring and avoiding harm in machine learning algorithms.
method Formal definition of harm and benefit using causal models, counterfactual objective functions.
result Demonstrates that standard machine learning methods can lead to harmful policies under distributional shifts.
DoSE improves OOD detection by estimating model probability density.
problem Poor specificity of model likelihoods for OOD detection.
method DoSE uses density of states concept to avoid direct model probability comparison.
result DoSE achieves state-of-the-art performance on OOD detection benchmarks.
We define pure radiation metrics with parallel rays to be n-dimensional pseudo-Riemannian metrics that admit a parallel null line bundle K and whose Ricci tensor vanishes on vectors that are orthogonal to K. We give necessary conditions in terms of the Weyl, Cotton and Bach tensors for a pseudo-Riemannian metric to be …
Bayesian model for cancer drug studies maps dose-response curves.
problem Mapping dose-response curves in cancer drug studies.
method Bayesian Tensor Filtering (BTF) with low-dimensional embeddings and structured shrinkage priors.
result BTF outperforms state-of-the-art methods in cancer drug studies.
Gaussian surrogates improve Poisson imaging performance at low doses.
problem Improving Poisson imaging performance at low doses.
method Analysis of Poisson and Gaussian surrogate reconstruction objectives under Poisson noise.
result Gaussian surrogates can achieve MSE comparable to Poisson MAP at low doses.
New CT image reconstruction method reduces X-ray dose while improving image quality.
problem Reducing X-ray dose in CT while maintaining image quality.
method Combines PWLS with learned sparsifying transform using alternating optimization and relaxed OS-LALM.
result Proposed method improves image quality for low dose levels compared to existing methods.
In this paper, the radiation field is defined for solutions to Einstein vacuum equations which are close to Minkowski space-time with spacial dimension n≥4. The regularity properties and asymptotic behavior of those Einstein vacuum solutions are established at the same time. In particular, the map from Cauchy int…
CMCO provides robust uncertainty estimates for neural operators without retraining.
problem Uncertainty quantification in deep learning for real-time virtual sensing.
method Unified Monte Carlo dropout and split conformal prediction in DeepONet.
result Near-nominal empirical coverage in diverse applications.
Develops a neural surrogate for proton dose calculation using Monte Carlo dropout uncertainty.
problem Computational demand in proton therapy workflows requiring repeated evaluations.
method Integrates Monte Carlo dropout into a neural network surrogate for fast, differentiable dose predictions and uncertainty quantification.
result Shows significant speedups over MC while retaining uncertainty information.
The paper proposes a system to accurately locate devices using millimeter wave radiation.
problem Accurate positioning of devices in urban environments with millimeter wave communications.
method Beamformed fingerprint learning using deep learning and pre-established beamforming patterns.
result Average estimation errors below 10 meters achievable in outdoor scenarios.
Paper develops methods to estimate derivative of dose-response curve for continuous treatments.
problem Estimating the derivative of the dose-response curve for continuous treatments.
method Doubly robust (DR) inference method using kernel smoothing, bias-corrected IPW and DR estimators.
result Proposes novel bias-corrected IPW and DR estimators for continuous treatments.
We discuss our recent work [4] in which gravitational radiation was studied by evaluating the Wang-Yau quasi-local mass of surfaces of fixed size at the infinity of both axial and polar perturbations of the Schwarzschild spacetime, à la Chandrasekhar [1].
A new model improves CT image quality from low-dose scans.
problem Improving CT image quality from low-dose scans.
method Multi-layer Residual Sparsifying Transform (MRST) learning model for low-dose CT reconstruction.
result The MRST model outperforms conventional methods in maintaining subtle details.
Paper proves existence of Hadamard states for Maxwell equations.
problem Proving existence of Hadamard states for Maxwell equations on spacetime.
method Introducing Cauchy radiation gauge and new Hodge decomposition.
result Existence of Hadamard states for Maxwell equations proven.
Deep learning detects corrosion in nuclear fuel canisters.
problem Ensuring safety and integrity of used nuclear fuel dry storage canisters.
method Residual neural networks (ResNets) for real-time corrosion detection of canister images.
result Deep learning approach accurately detects corrosion and classifies canisters as corroded or intact.