Paper integrates predictive and prescriptive tasks using bilevel optimization.
arXiv research
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A model learns symptom-drug relations for PD patients.
A new neural network model for optimal treatment assignment.
We address the problem of prescribing an optimal decision in a framework where the cost function depends on uncertain problem parameters that need to be learned from data. Earlier work proposed prescriptive formulations based on supervised machine learning methods. These prescriptive methods can factor in contextual in…
Paper solves curvature prescription problem on surfaces with boundary.
This paper addresses a novel data science problem, prescriptive price optimization, which derives the optimal price strategy to maximize future profit/revenue on the basis of massive predictive formulas produced by machine learning. The prescriptive price optimization first builds sales forecast formulas of multiple pr…
Study proves curvature prescription on spheres for k ≥ n/2.
Deep learning predicts drug prescriptions across global health records.
Prescribing, by conformal transformation, the kth-elementary symmetric polynomial of the Schouten tensor to be constant is a generalisation of the Yamabe problem. On compact Riemannian n-manifolds we show that, for k between and including 3 and n, this prescription equation is an Euler-Lagrange equation of some act…
PNNs improve treatment outcomes in TAVR and liver trauma.
The Prescriptive Canvas improves business outcomes by directly prescribing actions based on predictions.
The study compares Euclidean and cosine distances in medical drug prescription prediction.
ODTLearn learns optimal decision trees for predictive and prescriptive tasks.
Study conformal invariants from nodal sets on manifolds with boundary.
Method learns optimal treatment policies from observational data.
In this paper, we study conformal invariants that arise from nodal sets and negative eigenvalues of conformally covariant operators; more specifically, the GJMS operators, which include the Yamabe and Paneitz operators. We give several applications to curvature prescription problems. We establish a version in conformal…
New approach for estimating individual treatment effects in low compliance settings.
Two problems concerning asymptotically hyperbolic manifolds with an inner boundary are studied. First, we study scalar curvature presciption with either Dirichlet or mean curvature prescription interior boundary condition. Then we apply those results to the Lichnerowicz equation with (future or past) apparent horizon i…
The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in the epidemic. Individuals who are prescribed opioids, and who are diagnosed wit…
Local classification of surfaces and hypersurfaces with radial mean curvature.
The paper solves CR curvature prescription on pseudo-Einstein 3-manifolds.
P.Lecomte has proposed to take into account the covariant derivatives used to build ordering prescriptions for the naturality of transformation properties and has conjectured that there exists an natural ordering prescription for differential operators of any orders between density bundles which in addition is invarian…
Dynamic treatment recommendation systems based on large-scale electronic health records (EHRs) become a key to successfully improve practical clinical outcomes. Prior relevant studies recommend treatments either use supervised learning (e.g. matching the indicator signal which denotes doctor prescriptions), or reinforc…
Solves curvature prescription on rotational surfaces.
In this paper we give a new proof of a theorem by Alexandrov on the Gauss curvature prescription of Euclidean convex sets. This proof is based on the duality theory of convex sets and on optimal mass transport. A noteworthy property of this proof is that it does not rely neither on the theory of convex polyhedra nor on…
In this note we establish the large time non-negativity of the heat kernel for a class of elliptic differential operators on closed, Riemannian manifolds, and apply this result to a problem from conformal differential geometry.
In this paper, we combine ideas from machine learning (ML) and operations research and management science (OR/MS) in developing a framework, along with specific methods, for using data to prescribe optimal decisions in OR/MS problems. In a departure from other work on data-driven optimization and reflecting our practic…
Solves Dirichlet problem for prescribed scalar curvature in Anti-de Sitter space
PNNs improve personalized healthcare policies using mixed integer programming.
For any compact manifold of dimension n>=5, we prescribe the volume and any finite part of the spectrum of the Hodge Laplacian acting on diffential forms of degree 1<p<n-1 (exept for p=n/2 if n is even), within a given conformal class. When n<5 and when p=0,1,n-1,n, and p=n/2 if n is even, this simultaneous prescriptio…
The paper introduces a framework for prescriptive process monitoring that generates alarms to prevent or mitigate undesired outcomes.
We study conformal invariants that arise from functions in the nullspace of conformally covariant differential operators. The invariants include nodal sets and the topology of nodal domains of eigenfunctions in the kernel of GJMS operators. We establish that on any manifold of dimension , there exist many metr…
We augment linear Support Vector Machine (SVM) classifiers by adding three important features: (i) we introduce a regularization constraint to induce a sparse classifier; (ii) we devise a method that partitions the positive class into clusters and selects a sparse SVM classifier for each cluster; and (iii) we develop a…
We prove that, for a generic set of smooth prescription functions on a closed ambient manifold, there always exists a nontrivial, smooth, closed hypersurface of prescribed mean curvature . The solution is either an embedded minimal hypersurface with integer multiplicity, or a non-minimal almost embedded hypersur…
Paper proposes a method to quantify and explain machine learning uncertainty in predictive process monitoring.
We extend our studies of a quantum field model defined on a lattice having the dilation group as a local gauge symmetry. The model is relevant in the cross-disciplinary area of econophysics. A corresponding proposal by Ilinski aimed at gauge modeling in non-equilibrium pricing is realized as a numerical simulation of t…
The paper solves curvature prescription problems on balls and disks.
We prove the existence of metrics with prescribed -curvature under natural assumptions on the sign of the prescribing function and the background metric. In the dimension four case, we also obtain existence results for curvature forms requiring only restrictions on the Euler characteristic. Moreover, we derive a pre…
We study a market model in which the volatility of the stock may jump at a random time from a fixed value to another fixed value. This model was already described in the literature. We present a new approach to the problem, based on partial derivative equations, which gives a different perspective to the problem. Withi…
Study uses machine learning to analyze state drug policies and reduce overdose deaths.
Let be an open Riemann surface and be an integer. We prove that on any closed discrete subset of one can prescribe the values of a conformal minimal immersion . Our result also ensures jet-interpolation of given finite order, and hence, in particular, one may in addition prescribe the…
This paper considers the prescribed zero scalar curvature and mean curvature problem on the n-dimensional Euclidean ball for . Given a rotationally symmetric function , in this work, we will prove that if changes signs where and also satisfies a flatness con…
In this paper it is hown that given any smooth, positive function f on a closed, smooth manifold of dimension greater than four and with positive Paneitz invariant, there exists a metric on M such that = f.
The paper solves curvature prescription on a disk with negative Gaussian curvature.
Optimizes decisions without knowing the true distribution using historical data.
Study uses holography to analyze entanglement entropy in deformed CFTs.
Researchers solve the negative Yamabe case for scalar curvature prescription.
The paper tackles robust statistical methods using Wasserstein DRO formulations.