Bayesian networks learn sub-population differences from data.
problem Inference from a single network structure can be misleading when data populations are heterogeneous.
method A mixture of Bayesian networks where component probabilities depend on individual characteristics.
result Identifies both network structures and demographic predictors of sub-population membership.
This work shifts focus from prediction to intervention in social systems.
problem The limitations of focusing solely on prediction in automated decision systems.
method Shift from prediction-focused paradigm to intervention-oriented approach.
result A new perspective unifies statistical frameworks and tools for ADS design, implementation, and evaluation.
Our goal is to identify beneficial interventions from observational data. We consider interventions that are narrowly focused (impacting few covariates) and may be tailored to each individual or globally enacted over a population. For applications where harmful intervention is drastically worse than proposing no change…
Unified framework for estimating indirect effects in observational studies with unmeasured confounding.
problem Challenges in evaluating indirect effects due to unmeasured confounding and unethical exposures.
method Developed a unified identification and estimation framework using proximal causal inference.
result Unified identification and estimation of PIIE and causal effect of an intervening variable in settings with pervasive unmeasured confounding.
In a wide variety of applications, including personalization, we want to measure the difference in outcome due to an intervention and thus have to deal with counterfactual inference. The feedback from a customer in any of these situations is only 'bandit feedback' - that is, a partial feedback based on whether we chose…
With the aim of building machine learning systems that incorporate standards of fairness and accountability, we explore explicit subgroup sample complexity bounds. The work is motivated by the observation that classifier predictions for real world datasets often demonstrate drastically different metrics, such as accura…
Study uses PPLs to model and forecast COVID-19 spread and policy interventions.
problem Forecast and control the spread of COVID-19 using policy interventions.
method Compartmental models, probabilistic programming, inference, greedy algorithm.
result Optimal series of policy interventions can control the infected population.
Paper tackles estimating individual treatment effects from observational data.
problem Estimating the difference between outcomes with and without treatment from single observation.
method Formulated as inference from hidden variables, uses a model of four causal populations, proposes ECM algorithm.
result ECM algorithm provides better performance compared to baseline methods on synthetic and real-world data.
A-ICP selects experiments to learn causal effects efficiently.
problem Learning causal effects from observational data is difficult.
method Active learning framework based on Invariant Causal Prediction.
result Proposes intervention selection policies to reveal direct causes.
The method of covariate adjustment is often used for estimation of population average treatment effects in observational studies. Graphical rules for determining all valid covariate adjustment sets from an assumed causal graphical model are well known. Restricting attention to causal linear models, a recent article der…
Study finds incorporating fairness in healthcare models doesn't improve performance or net benefit.
problem Addressing health inequities in healthcare through algorithmic fairness.
method Empirical case study using models to estimate atherosclerotic cardiovascular disease risk.
result Incorporating fairness considerations into model training objective does not improve model performance or net benefit.
Feature selection predicts immune state changes in RA mouse model.
problem Predicting the immune state change after RA immunotherapy.
method Feature selection algorithms applied to mouse CIA model data.
result Selected features predict both T cell markers and treatment efficacy.
We present new methods to estimate causal effects retrospectively from micro data with the assistance of a machine learning ensemble. This approach overcomes two important limitations in conventional methods like regression modeling or matching: (i) ambiguity about the pertinent retrospective counterfactuals and (ii) p…
Objective: Predict patient-specific vitals deemed medically acceptable for discharge from a pediatric intensive care unit (ICU). Design: The means of each patient's hr, sbp and dbp measurements between their medical and physical discharge from the ICU were computed as a proxy for their physiologically acceptable state …
New algorithm balances personalization and statistical validity in MRTs.
problem Optimizing decisions in nonstationary settings with habituation and recovery.
method ROGUE-TS Thompson Sampling with probability clipping.
result Achieves lower regret and maintains high statistical power.
Holdout set improves risk score accuracy without biasing predictions.
problem Updating risk scores can lead to biased estimates when directly applied.
method Use a holdout set of non-intervention population to update risk scores.
result Optimal holdout size reduces adverse outcomes to optimal level.
Computers are increasingly used to make decisions that have significant impact in people's lives. Often, these predictions can affect different population subgroups disproportionately. As a result, the issue of fairness has received much recent interest, and a number of fairness-enhanced classifiers and predictors have…
The paper develops a method to predict ICU mortality risk across diverse patient populations.
problem Improving patient survival by recognizing risky trajectories during ICU stays.
method Domain adaptation strategies to learn mortality prediction models robust to diverse ICU populations.
result The proposed model outperforms baselines, achieving AUC numbers up to 0.88 for the Cardiac ICU population.
The study quantifies and compares aleatoric and epistemic discrimination in ML models.
problem Sources of discrimination in ML models and their impact on performance.
method Quantifying aleatoric and epistemic discrimination using statistical experiments and model accuracy.
result State-of-the-art fairness interventions are effective at removing epistemic discrimination but not aleatoric discrimination in datasets with missing values.
Observational cohort studies with oversampled exposed subjects are typically implemented to understand the causal effect of a rare exposure. Because the distribution of exposed subjects in the sample differs from the source population, estimation of a propensity score function (i.e., probability of exposure given basel…
AI improves precision health through adaptive interventions.
problem Improving healthcare through personalized and dynamic treatments.
method Reinforcement learning (RL) for adaptive interventions in digital health.
result RL shows promise in dynamic healthcare problems.
Study finds real-world datasets contain natural experiments that can improve model performance.
problem Detecting natural experiments in real-world datasets for causal inference.
method Synthetic graph simulation and feature selection based on causal links.
result Real-world datasets contain natural experiments that can be exploited for improved model performance.
The paper identifies the best treatment to maximize NDPO, a key outcome in causal mediation analysis.
problem Identifying the treatment that maximizes the expected natural direct potential outcome (NDPO) in causal mediation analysis.
method Developed a fixed-confidence best-arm identification (BAI) algorithm based on the Track-and-Stop (TaS) framework, using a cutting-set method to solve a semi-infinite optimization problem.
result The proposed algorithm achieves sample-efficient identification with a high-probability correctness guarantee and asymptotic optimality.
The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in the epidemic. Individuals who are prescribed opioids, and who are diagnosed wit…
Proposes a resampling method to compare uplift models with uncertainty.
problem Uncertainty in estimating uplift curves when full population data is unavailable.
method Two-step sampling procedure and resampling-based approach.
result Validates the proposed method through simulations and real data applications.
The emergence of an ageing population is a significant public health concern. This has led to an increase in the number of people living with progressive neurodegenerative disorders like dementia. Consequently, the strain this is places on health and social care services means providing 24-hour monitoring is not sustai…
Diabetes is a major public health problem in the United States, affecting roughly 30 million people. Diabetes complications, along with the mental health comorbidities that often co-occur with them, are major drivers of high healthcare costs, poor outcomes, and reduced treatment adherence in diabetes. Here, we evaluate…
Although there are millions of transgender people in the world, a lack of information exists about their health issues. This issue has consequences for the medical field, which only has a nascent understanding of how to identify and meet this population's health-related needs. Social media sites like Twitter provide ne…
Estimates joint causal effects using single-variable interventions on nonlinear models.
problem Estimating joint causal effects from single-variable interventions.
method Identifiability result and practical estimator for decomposing causal effects.
result Joint effects can be inferred without joint interventional data for nonlinear additive models.
This paper tackles CRL for multi-node interventions, achieving identifiability guarantees.
problem CRL under unknown multi-node interventions, focusing on single-node assumptions.
method Establishes identifiability results for general latent causal models under stochastic interventions.
result Identifiability up to ancestors using soft interventions, perfect identifiability using hard interventions.
We consider the problem of learning causal directed acyclic graphs from an observational joint distribution. One can use these graphs to predict the outcome of interventional experiments, from which data are often not available. We show that if the observational distribution follows a structural equation model with an …
This work tackles causal graph discovery with stochastic interventions to minimize the number of interventions.
problem Discovering the true causal graph from observational data with limited interventions.
method Proposes a stochastic intervention model and studies verification and search problems with approximation algorithms.
result Provides approximation algorithms with competitive ratios for verification and search problems.
Causal diagrams based on do intervention are useful tools to formalize, process and understand causal relationship among variables. However, the do intervention has controversial interpretation of causal questions for non-manipulable variables, and it also lacks the power to check the conditions related to counterfactu…
New method uses data augmentation to improve causal effect estimation.
problem Improving causal effect estimation in the presence of hidden confounders.
method Introduces IV-like regression and data augmentation techniques.
result Data augmentation can simulate worst-case scenarios for causal estimation.
Paper proposes scalable algorithm to estimate intervention targets in linear models.
problem Estimating intervention targets in linear models from observational and interventional data.
method The paper proposes a scalable algorithm that estimates intervention sites from the difference between precision matrices of observational and interventional datasets.
result The algorithm consistently identifies all intervention targets and updates observational Markov equivalence classes to interventional ones.
It is not clear how to target patients who are most likely to benefit from digital care management programs ex-ante, a shortcoming of current risk score based approaches. This study focuses on defining impactability by identifying those patients most likely to benefit from technology enabled care management, delivered …
EGDL predicts TB outbreaks with deep learning, integrating epidemiological models.
problem Predicting TB outbreaks with complex spatiotemporal dynamics.
method Modified MN-SIR model with Bayesian inference, deep neural networks.
result EGDL delivers robust and accurate TB outbreak predictions.
We study the problem of estimating the continuous response over time to interventions using observational time series---a retrospective dataset where the policy by which the data are generated is unknown to the learner. We are motivated by applications where response varies by individuals and therefore, estimating resp…
New method disentangles mixed interventional and observational data in SEMs.
problem Learning causal relationships from mixed interventional and observational data.
method Developed a method to disentangle mixed interventional and observational data in linear SEMs with Gaussian noise.
result The method can identify causal graphs up to their interventional Markov Equivalence Class.
The paper presents a method to estimate joint interventional distributions from marginal interventional data.
problem Estimating joint interventional distributions from marginal interventional data.
method The paper extends the Causal Maximum Entropy method to use interventional data and employs Lagrange duality to prove the solution lies in the exponential family.
result The method allows for causal feature selection and inference of joint interventional distributions.
Bayesian method for causal discovery from unknown general interventions.
problem Learning causal DAGs from unknown interventions that modify parent sets.
method Bayesian approach with MCMC for approximating posterior DAGs and intervention targets.
result Bayesian method can identify DAGs and intervention targets up to equivalence classes.
Interventional data helps identify latent factors without distributional assumptions.
problem Identifying latent factors from interventional data without distributional assumptions.
method Leveraging geometric signatures of latent factors' support from interventional data.
result Latent causal factors can be identified up to permutation and scaling given data from perfect do-interventions.
IntDC framework uncovers causal relationships from non-interventional data.
problem Detecting causal relationships in non-interventional complex systems.
method Interventional Embedding Entropy (IEE) for causal strength measurement.
result IEE accurately finds causal edges and quantifies causal strength robustly.
Deep learning using neural networks has provided advances in image style transfer, merging the content of one image (e.g., a photo) with the style of another (e.g., a painting). Our research shows this concept can be extended to analyse the design of streetscapes in relation to health and wellbeing outcomes. An Austral…
Algorithm detects causal change points quickly with adaptive interventions.
problem Detecting changes in causal models with interventions.
method Centralization technique, Kullback-Leibler divergence for intervention selection, adaptive intervention policy.
result Theoretical first-order optimality and validation through simulations and real-world studies.
Method learns causal effects from multiple interventions in presence of unobserved confounders.
problem Disentangling causal effects from sets of interventions in the presence of unobserved confounders.
method Non-linear structural causal models with additive, multivariate Gaussian noise; algorithm that learns causal model parameters by pooling data from different regimes and maximizing combined likelihood.
result Identification proofs demonstrate that causal effects of single interventions can be learned from sets of interventions, even with unobserved confounders.
New algorithms improve causal graph discovery with adaptive interventions, even under worst-case interventional costs.
problem Discover causal relationships from data with adaptive interventions and node-dependent costs.
method Define new benchmarks and provide adaptive search algorithms for causal graph discovery.
result Logarithmic approximations achieved under various settings: atomic, bounded size interventions and generalized cost objectives.
We address the problem of optimal Central Bank intervention in the exchange rate market when interventions create feedback in the rate dynamics. In particular, we extend the work done on optimal impulse control by Cadenillas and Zapatero to incorporate temporary market reactions, of random duration and level, to Bank i…