Investigates the number of experiments needed for statistical significance in medication testing.
problem Determining the number of experiments needed for a statistically significant result.
method Examines binomial and general probability distributions, considering placebo efficacy and varying distributions.
result The number of experiments needed can be significantly higher when placebo efficacy is considered.
Proposes a method to correct for covariate shift in meta-analysis of randomized trials.
problem Invalidation of standard IPD meta-analysis due to covariate shift across studies.
method Placebo-anchored transport framework that treats source-trial outcomes as proxy signals and target-trial placebo outcomes as gold labels.
result Yields target-identified effect estimates in connected targets and a principled screen--then--transport procedure in disconnected targets.
GP-CATE calibrates CATE intervals in few-placebo trials with Gaussian processes.
problem Calibrating uncertainty intervals for CATE in small-arm trials.
method GP-CATE uses Gaussian processes to model each arm's outcome surface directly.
result GP-CATE achieves calibrated coverage where other methods fail.
Study identifies 1,012 persistent wallet cohorts on Solana pump.fun, showing coordinated buying behavior.
problem Understanding coordinated buying behavior on Solana pump.fun.
method Two-stage detection pipeline: first-buyer-window extraction followed by persistent-cohort surfacing via graph co-occurrence.
result 1,012 persistent wallet cohorts identified, showing systematic co-buying across multiple launches.
Improved forecasting of investment dynamics across heterogeneous panels using a two-stage model.
problem Forecasting investment dynamics in heterogeneous panels with varying dynamics.
method Two-stage architecture: global pooled AR(1) for shared persistence, local models for residual dynamics.
result Significant improvement in out-of-sample R2 from 0.630 to 0.677, with a gain of 0.047. HSR reduces analyst earnings forecast errors by lowering travel friction.
problem How HSR connectivity affects analyst earnings forecast errors in China.
method Firm-year panel data from 2008-2019; placebo test to rule out pre-existing trends.
result HSR reduces analyst earnings forecast errors after connectivity, not before.
Audit financial machine learning workflows to detect spurious predictability.
problem Spurious predictability in financial machine learning models.
method Falsification audit testing predictive workflows against synthetic environments.
result Many apparent financial predictions are artifacts, not genuine.
New disease drug trials use ML to predict best therapy.
problem Developing new drugs faster than usual clinical trials.
method Use Neural Network to predict drug effects from patient data.
result Neural Network outperforms traditional placebo-controlled trials.
Generative AI boosts analyst reports but increases forecast errors.
problem Improving financial analyst reports with AI.
method Natural experiment using FactSet's AI platform.
result AI-assisted reports are more comprehensive but lead to higher forecast errors.
Cryptocurrency markets show higher spreads during extreme fear and greed phases.
problem Understanding and predicting liquidity withdrawal in cryptocurrency markets.
method Analysis of Crypto Fear & Greed Index and Bitcoin daily data.
result Extreme fear and greed regimes exhibit significantly higher spreads than neutral periods.
Study uses exchangeable GPs for staggered-adoption policy evaluation in panel data.
problem Evaluating the impact of staggered treatments in panel data settings.
method Exchangeable multi-task Gaussian processes (GPs) with flexible kernels.
result Flexible tool for policy evaluation in panel data settings.
Schizophrenia, a mental disorder that is characterized by abnormal social behavior and failure to distinguish one's own thoughts and ideas from reality, has been associated with structural abnormalities in the architecture of functional brain networks. Using various methods from network analysis, we examine the effect …
Reducing volatility proxy improves apparent market correlation dynamics.
problem Attributing apparent slow collective market dynamics to intrinsic or driver inheritance.
method Coupled Ornstein-Uhlenbeck model with VIX proxy, decomposing and controlling for autocorrelation.
result VIX-coupled model reduces effective relaxation time from 298 to 61 trading days, improving fit over bare mean reversion.
Multiple Sclerosis (MS) is a neurodegenerative disorder characterized by a complex set of clinical assessments. We use an unsupervised machine learning model called a Conditional Restricted Boltzmann Machine (CRBM) to learn the relationships between covariates commonly used to characterize subjects and their disease pr…
Geopolitical and geoeconomic shocks affect sovereign risk differently, with distinct transmission channels.
problem Understanding how geopolitical and geoeconomic shocks impact sovereign credit risk.
method Daily panel data of 42 economies over 2018-2025; semistructural framework; Shapley-Taylor decomposition; machine learning predictions; placebo and sign-restricted SVAR evidence.
result Geopolitical shocks primarily increase sovereign credit spreads through direct repricing, while geoeconomic shocks mainly affect spreads through financial conditions and policy uncertainty.
The study finds that supply chain information from LLM embeddings improves stock returns predictions.
problem Predicting stock returns using textual information from annual reports.
method Combining LLM embeddings of annual reports with supply chain knowledge graph propagation.
result Network-augmented embeddings significantly predict stock returns with a Sharpe ratio of 0.86 and alpha of 7.27%.
LLM trading agents show risk feedback can improve alignment without fine-tuning.
problem Aligning LLM trading agents with financial risk.
method TradeArena testbed, risk reports, execution simulation, memory replay.
result Risk feedback can improve alignment without fine-tuning, but not universally.
Order-flow entropy predicts price magnitude without directionality.
problem Predicting price magnitude in financial markets.
method Real-time order-flow entropy computed from a 15-state Markov transition matrix.
result Order-flow entropy predicts the magnitude of intraday returns with high accuracy.
A common statistical problem in econometrics is to estimate the impact of a treatment on a treated unit given a control sample with untreated outcomes. Here we develop a generative learning approach to this problem, learning the probability distribution of the data, which can be used for downstream tasks such as post-t…
The leverage effect refers to the generally negative correlation between the return of an asset and the changes in its volatility. There is broad agreement in the literature that the effect should be present for theoretical reasons, and it has been consistently found in empirical work. However, a few papers have pointe…
New method for interpreting non-linear models using forward marginal effects.
problem Interpreting non-linear models' feature effects is challenging.
method Introducing forward marginal effects and partitioning feature space for better interpretation.
result Improved interpretation of non-linear prediction functions.
The Kalinin effectivity is studied and applied to compactifications and Hilbert squares.
problem Understanding Kalinin effectivity in compactifications and its applications.
method Definition, construction methods, and analysis of Kalinin effectivity in various compactifications.
result Wonderful compactifications of hyperplane arrangements and configuration spaces are Kalinin effective.
New method estimates treatment effects in network data, accounting for spillover effects.
problem Treatment effect estimation in networks with spillover effects.
method Augmented inverse probability weighting (AIPW) with cross-fitting and machine learning.
result Semiparametric treatment effect estimator converges at parametric rate and follows Gaussian distribution.
Causalfe estimates treatment effects in panel data with fixed effects.
problem Spurious heterogeneity in treatment effect estimates due to fixed effects in panel data.
method CFFE approach with node-level residualization during tree construction.
result Validates the estimator's performance through simulation studies.
The paper clarifies the distinction between CATE and ITE under ignorability assumptions.
problem Confusion between CATE and ITE hinders personalized effect estimation.
method Clarifies the distinction between CATE and ITE under ignorability assumptions.
result CATE and ITE are not necessarily the same under ignorability assumptions.
GADGET framework decomposes global feature effects using recursive partitioning.
problem Misleading global feature effects when feature interactions are present.
method Generalized additive decomposition of global effects (GADGET) based on recursive partitioning.
result Minimizes interaction-related heterogeneity of local feature effects.
A new RL framework evaluates dynamic mediation effects over time.
problem Dynamic mediation effects in sequentially assigned treatments.
method Reinforcement Learning framework for decomposition and estimation of causal effects.
result Superior performance demonstrated through numerical studies and real data analysis.
New memory effect discovered in gravitational wave behavior.
problem Understanding gravitational wave behavior in spacetimes with angular momentum.
method Mathematical analysis of Minkowski spacetime and Kerr black holes.
result Angular momentum memory effect observed at future null infinity.
Effective Yau-Tian-Donaldson conjecture for spherical varieties.
problem Finding effective K-stability criteria for spherical varieties.
method Formulated an effective variant of the Yau-Tian-Donaldson conjecture and reviewed effective K-stability criteria for spherical varieties.
result Effective K-stability criteria can be computed given combinatorial data.
A new method estimates treatment effects in mixed groups, improving accuracy.
problem Estimating treatment effects in mixed groups with heterogeneous responses.
method PCM (pre-cluster and merge) approach for nonparametric estimation.
result Asymptotic consistency and significant improvement in accuracy over existing methods.
Study estimates heterogeneous principal causal effects with binary treatments and intermediate variables.
problem Estimating subgroup effects within strata defined by potential values of an intermediate variable.
method Proposes a framework for estimating and forming confidence intervals for heterogeneous principal causal effects under principal ignorability assumption. Develops several estimators with varying robustness properties.
result Established large-sample theory and analyzed bias contributions of each approach.
Study develops method for estimating causal effects in continuous variables.
problem Lack of methods for estimating causal effects in continuous variables.
method Develops a method independent of data generating models for continuous variable interventions.
result Preserves identifiability of data and applies to any generating models.
ICA accurately estimates treatment effects even with confounders.
problem Estimating treatment effects in the presence of confounding variables.
method Uses Independent Component Analysis (ICA) to identify latent sources and estimate mixing coefficients.
result Linear ICA can consistently estimate multiple treatment effects, even with Gaussian confounders, and is more sample-efficient than Orthogonal Machine Learning (OML).
Method improves treatment effect estimation in randomized experiments.
problem Estimating distributional treatment effects in randomized experiments.
method Distributional regression framework with machine learning for variance reduction.
result The proposed method reduces variance of distributional treatment effect estimators.
New method discovers context effects in choice data.
problem Identifying context effects from choice data is challenging.
method Automatic discovery of context effects from observed choices.
result Automatic discovery of context effects from observed choices.
Dropout introduces both explicit and implicit regularization effects.
problem Understanding the full impact of dropout regularization.
method Disentangled explicit and implicit regularization effects through experiments and analytic simplifications.
result Explicit and implicit regularization effects of dropout are distinct and can be characterized analytically.
New test for binary treatment effects using kernel methods.
problem Testing distributional effects of binary treatments.
method Kernel-based doubly-robust test, avoiding permutations.
result Valid type-I error with computational efficiency.
New Krylov subspace methods speed up mixed-effects models with crossed random effects.
problem Slow computations for high-dimensional crossed random effects in mixed-effects models.
method Krylov subspace-based methods for generalized mixed-effects models with cross effects.
result Speedups by factors of up to 10,000 in computations for mixed-effects models.
The use of drug combinations, termed polypharmacy, is common to treat patients with complex diseases and co-existing conditions. However, a major consequence of polypharmacy is a much higher risk of adverse side effects for the patient. Polypharmacy side effects emerge because of drug-drug interactions, in which activi…
Previous literature has identified an effect, dubbed the Zumbach effect, that is nonzero empirically but conjectured to be zero in any conventional stochastic volatility model. Essentially this effect corresponds to the property that past squared returns forecast future volatilities better than past volatilities foreca…
Identifies causal effects in LiNGAM models with latent variables.
problem Identifying causal effects in LiNGAM models with latent confounders.
method Complete graphical characterization and efficient algorithms for certification. RICA adaptation for estimation.
result Efficient algorithms and RICA adaptation for estimating causal effects.
Develops HCQRF for estimating heterogeneous treatment effects with censored data.
problem Estimating heterogeneous treatment effects on censored responses with high-dimensional variables.
method Hybrid Censored Quantile Regression Forest (HCQRF) combining random forests and censored quantile regression.
result Demonstrates the effectiveness and stability of HCQRF through simulation studies and real-world application.
Study relaxes identification assumptions for natural direct effects in non-randomized settings.
problem Identifying causal direct effects under unmeasured confounding.
method Developed relaxed conditions for identifying natural direct effects in non-randomized settings.
result Identified natural direct effect under unmeasured confounding conditions.
The Sagnac effect is re-examined using Finslerian geometry.
problem Understanding the Sagnac effect in general relativity.
method Reviewing the geometry of the Sagnac effect with a focus on Finslerian metrics.
result An asymmetry in Finslerian metrics affects the Sagnac effect for both future-pointing null and timelike geodesics.
We study the relationship between national culture and the disposition effect by investigating international differences in the degree of investors' disposition effect. We utilize brokerage data of 387,993 traders from 83 countries and find great variation in the degree of the disposition effect across the world. We fi…
Method estimates treatment effect bounds in sample selection models.
problem Estimating heterogeneous treatment effects in presence of sample selection.
method Debiased/double machine learning approach for non-linear and high-dimensional confounders.
result Substantially tighter effect bounds for younger users.
XTNet estimates complex cross-treatment effects in multi-category, multi-valued settings.
problem Challenges in estimating causal effects for multi-category, multi-valued treatments.
method Dynamic Neural Masking for capturing treatment interactions without restrictive assumptions.
result XTNet consistently outperforms state-of-the-art baselines in multi-category, multi-valued treatment effect estimation.
The paper develops methods to identify stable associations across multiple studies.
problem Identifying stable associations across multiple studies with possible distributional shifts.
method Modeling heterogeneous multi-source data with multiple high-dimensional regressions and devising a novel sampling method for valid confidence intervals of maximin effects.
result Significant maximin effects indicate stable associations that can be generalized to target populations.