HiP-MDPs help personalize HIV treatment across patient variations.
problem Physiological variation leads to different responses to treatments.
method Embed tasks in a low-dimensional space, updating HiP-MDP framework.
result Robust personalized medicine strategies developed for HIV treatment.
Generative model improves TMP reconstruction from ECG data.
problem Reconstructing cardiac transmembrane potential from surface ECG data is an ill-posed inverse problem.
method A novel model-constrained inference framework using a variational auto-encoder (VAE) with LSTM networks to learn the conditional likelihood of TMP and the prior distribution of generative factors.
result The method significantly improves TMP reconstruction accuracy compared to conventional methods.
Model reconstructs missing EKG data more accurately than baseline.
problem Reconstruct missing EKG data with high accuracy.
method Developed a probabilistic model of cardiac electrophysiology and EKG measurement process.
result Model outperforms baseline in reconstructing missing EKG data.
Personalized time series models improve drug response prediction.
problem Fitting time series models to cohorts ignoring individual variation.
method Multi-task learning applied to time series data with and without control inputs.
result Improved predictive accuracy and uncertainty estimation.
Late fusion of clinical notes and physiological data improves ICU mortality prediction.
problem Improving ICU mortality prediction using multimodal data.
method Late fusion of clinical notes and physiological time series data with a deep learning architecture.
result Late fusion approach provides statistically significant improvement in mortality prediction performance.
Detects physiological patterns to hemodynamic stress using unsupervised deep learning.
problem Identify and characterize physiological responses to hemorrhage in raw vital sign data.
method Transform vital sign time series into latent space using unsupervised deep learning, identify clusters, and evaluate latent embeddings.
result Clusters in latent embeddings correspond to physiological response patterns matching physicians' intuition.
Model improves emotion recognition using multiple physiological signals.
problem Single physiological signal is insufficient for accurate emotion recognition.
method Fused multiple modal physiological signals (EEG, EMG, EOG) for emotion classification.
result Best classification accuracy of 94.42% on arousal and 94.02% on valence in two-class tasks.
Study builds complex network from multimodal physiological data.
problem Understanding dynamic interactions in biological systems.
method Network-based multimodal data fusion using recurrence plots and temporal metrics.
result Model accurately characterizes emotional states through physiological responses.
PULSE learns representations from physiological time series.
problem Lack of effective pretraining objectives for physiological time series.
method Proposes a pretraining framework exploiting dynamical systems generative model.
result PULSE learns representations that distinguish semantic classes and improve transfer learning.
Hybrid Amortized Inference improves PPG model interpretability.
problem Tension between PPG biomarker accuracy and clinical interpretability.
method Introduces PPGen for biophysical PPG signal-physiological parameter relation, and HAI for fast, robust estimation.
result Hybrid Amortized Inference accurately infers physiological parameters from PPG signals.
Adversarial transfer learning improves stress assessment across users.
problem Transfer learning challenges in physiological biosignals.
method Disentangled nuisance-robust representations using adversarial networks.
result Adversarial framework enhances cross-subjects stress assessment.
PHASE predicts surgical complications from physiological signals.
problem Predicting adverse surgical outcomes from physiological signals.
method Self-supervised transfer learning for physiological signals.
result PHASE outperforms other approaches in predicting five surgical complications.
Advances of modern sensing and sequencing technologies generate a deluge of high dimensional space-temporal physiological and next-generation sequencing (NGS) data. Physiological traits are observed either as continuous random functions, or on a dense grid and referred to as function-valued traits. Both physiological a…
This paper addresses the problem of emotion recognition from physiological signals. Features are extracted and ranked based on their effect on classification accuracy. Different classifiers are compared. The inter-subject variability and the personalization effect are thoroughly investigated, through trial-based and su…
Semi-supervised learning method augments minority class examples for robust anomaly detection in clinical signals.
problem Class imbalance in minority class instances impairs robustness of clinical analytics solutions.
method Intelligent augmentation of minority class examples to balance class distribution and construct a smooth decision boundary.
result The proposed method outperforms state-of-the-art algorithms in anomaly detection for clinical signals.
CLOPS improves deep learning for continuous physiological data.
problem Deep learning struggles with streaming, multi-sensor clinical data.
method CLOPS is a replay-based continual learning strategy.
result CLOPS outperforms state-of-the-art methods in continual learning scenarios.
Study classifies human stress using EEG, GSR, and PPG signals.
problem Classifying perceived human stress using physiological signals.
method Data acquisition, feature extraction (time domain), classification using multiple classifiers (SVM, Naive Bayes, MLP).
result Best classification accuracy of 75% achieved by MLP classifier.
A new model uses GPs and latent force models to predict patient responses to drugs.
problem Challenges in modeling short-term effects of drugs on patient physiology.
method Hybrid Gaussian process with latent force model for joint modeling of patient physiology and drug effects.
result The model accurately predicts patient responses to three common drugs, showing competitive performance.
Proposes a framework for extracting consistent physiological features across users.
problem Variability of biosignals across different users and tasks.
method Adversarial feature extractor for disentangled universal representations.
result Up to 8.8% improvement in average accuracy of classification.
The paper proposes a machine learning method to detect drivers' affective states using physiological signals.
problem Detecting and assessing drivers' affective states to improve driving safety and well-being.
method Multiview multi-task machine learning approach using physiological signals.
result Accounting for drive-specific differences significantly improves model performance.
UNHaP removes noise from physiological events using Hawkes processes.
problem Challenges in identifying true events from spurious ones in physiological signal analysis.
method UNHaP uses marked Hawkes processes to distinguish and unmix true events from noise.
result UNHaP significantly reduces false detection rates and enhances event understanding.
PerCDL learns personalized dictionaries for physiological signals combining global and local structures.
problem Representing datasets with both global and local structures in human physiological signals.
method Personalized Convolutional Dictionary Learning (PerCDL) that combines a global and personalized local dictionary.
result PerCDL effectively learns interpretable representations for human locomotion data.
Understanding the adaptation process of plants to drought stress is essential in improving management practices, breeding strategies as well as engineering viable crops for a sustainable agriculture in the coming decades. Hyper-spectral imaging provides a particularly promising approach to gain such understanding since…
Bayesian model detects internal bleeding in ICU patients.
problem Late detection of internal bleeding in ICU patients.
method Bayesian regime switching model analyzing vitals and labs.
result Probabilistic assessment of patient's physiological state.
We developed a new approach for the analysis of physiological time series. An iterative convolution filter is used to decompose the time series into various components. Statistics of these components are extracted as features to characterize the mechanisms underlying the time series. Motivated by the studies that show …
We investigate how simultaneously recorded long-range power-law correlated multi-variate signals cross-correlate. To this end we introduce a two-component ARFIMA stochastic process and a two-component FIARCH process to generate coupled fractal signals with long-range power-law correlations which are at the same time lo…
Predicts physiologically acceptable states for pediatric ICU discharge.
problem Determining physiologically stable states for pediatric ICU discharge.
method Computed PASS values from hr, sbp, and dbp measurements, compared to age-normal and polynomial regression predictions.
result RNN model predictions were more accurate than age-normal vitals.
The relation between performance and stress is described by the Yerkes-Dodson Law but varies significantly between individuals. This paper describes a method for determining the individual optimal performance as a function of physiological signals. The method is based on attention and reasoning tests of increasing comp…
CardiacGen generates realistic ECG signals for training deep learning models.
problem Creating realistic synthetic ECG signals for training deep learning models.
method Hierarchical deep generative model with multi-objective loss functions.
result Synthetic ECG signals from CardiacGen can be used for data augmentation and improve classifier performance.
Motivation: Cell-biological processes are regulated through a complex network of interactions between genes and their products. The processes, their activating conditions, and the associated transcriptional responses are often unknown. Organism-wide modeling of network activation can reveal unique and shared mechanisms…
Algorithm selects optimal segment for physiological signal analysis.
problem Physiological signals are often corrupted by noise, requiring selective analysis.
method Combines deep neural networks for signal analysis and combinatorial optimization for segment selection.
result Significant improvement in system performance, e.g. 2.4% increase in sensitivity for heart sound segmentation.
UniPhyNet improves cognitive load classification accuracy using EEG, ECG, and EDA signals.
problem Classifying cognitive load using multimodal physiological data.
method Unified network architecture integrating multiscale parallel convolutional blocks, ResNet-type blocks, and channel block attention module. Uses bidirectional gated recurrent unit for temporal dependencies.
result Improves raw signal classification accuracy from 70% to 80% (binary) and 62% to 74% (ternary) on CL-Drive dataset.
New model predicts blood glucose in diabetics with improved accuracy.
problem Forecasting blood glucose in type 1 diabetics with high accuracy.
method Integrates machine learning with existing biomedical model to capture time-varying dynamics.
result Improved long-term forecasting of blood glucose up to 6 hours.
This paper investigates the use of distributed processing on the problem of emotion recognition from physiological sensors using a popular machine learning library on distributed mode. Specifically, we run a random forests classifier on the biosignal-data, which have been pre-processed to form exclusive groups in an un…
PhysioMTL learns personalized HRV rhythms from wearable data, improving prediction and counterfactual analysis.
problem Challenges in interpreting HRV measurements due to variability and stressors.
method PhysioMTL combines Optimal Transport and MTL to learn personalized diurnal rhythms from heterogeneous data.
result PhysioMTL outperforms other methods in predicting unseen subjects and generating counterfactual effects.
A new method learns complex dynamical systems from data efficiently.
problem Learning complex dynamical systems from large-scale data efficiently.
method Low-rank structured variational autoencoding framework for nonlinear Gaussian state-space models.
result Consistently demonstrates better predictive capabilities compared to other models.
Predicts individual septic shock children's vasoactive response using RNN.
problem Personalized physiologic responses to vasoactive titrations in septic shock children.
method Retrospective analysis of EMR data using a Recurrent Neural Network (RNN).
result RNN model predicted physiologic responses more accurately than a linear model.
Study explores DNNs' reliance on existing vs. new features in physiological signals.
problem Understanding how deep neural networks discover new features in physiological signals.
method Proposes a method to remove hand-engineered features and force DNNs to learn new representations.
result DNNs often rediscover known features, but can also learn new ones.
Functional brain networks exhibit dynamics on the sub-second temporal scale and are often assumed to embody the physiological substrate of cognitive processes. Here we analyse the temporal and spatial dynamics of these states, as measured by EEG, with a hidden Markov model and compare this approach to classical EEG mic…
Bayesian model for multi-environment prediction with latent variable changes.
problem Prediction in environments with changing latent variable distributions.
method Bayesian model with empirical Bayes prior and amortized variational algorithm.
result Method outperforms previous approaches in new environments.
Paper identifies resting positions using EGG, ECG, respiration rate, and SpO2.
problem Identifying the resting position for health monitoring.
method Hybrid stacked ensemble machine learning model combining Decision tree, Random Forest, and Xgboost.
result 100% accurate prediction of resting positions.
A neuron is a basic physiological and computational unit of the brain. While much is known about the physiological properties of a neuron, its computational role is poorly understood. Here we propose to view a neuron as a signal processing device that represents the incoming streaming data matrix as a sparse vector of …
Personalized stress model using transfer learning from 20 participants.
problem Limited generalizability of machine learning models due to individual physiological differences.
method Transfer learning from a base model trained on 20 participants' physiological data collected in real-time.
result Improved model personalization and cross-domain performance.
DecompKAN improves time series forecasting accuracy and transparency.
problem Accurate and transparent time series forecasting in scientific domains.
method Combines decomposition, patching, normalization, and B-spline KAN edge functions.
result Achieves best or tied-best MSE on 20 of 36 comparisons across 9 datasets.
Energy consumption is an important issue in continuous wireless telemonitoring of physiological signals. Compressed sensing (CS) is a promising framework to address it, due to its energy-efficient data compression procedure. However, most CS algorithms have difficulty in data recovery due to non-sparsity characteristic…
Neural network predicts falls in elderly people up to 10 minutes in advance.
problem Falls prevention in elderly people, especially in aging societies.
method Gated Recurrent Unit (GRU) based neural networks model using heart rate and mean blood pressure signals.
result Predicted syncope occurrence approximately 10 minutes before manual markers.
Enhances causal estimation using unlabeled offline ICU data.
problem Assessing unmeasured physiological variables in new ICU patients.
method Three-stage approach: non-causal and causal estimators, causal filter, and prediction for new patients.
result Enhanced causal estimation for new ICU patients using offline data.
End-to-end classifier predicts sepsis from clinical data.
problem Predicting sepsis onset from clinical data with high accuracy.
method Multitask Gaussian process RNN classifier for multivariate time series.
result Outperforms baselines, improving AUC and PRC.