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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,695 papers · 148 categories

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1122 · May 201919922001200920172026
35 results for electrophysiology

Sparse neural networks visualize paired transcriptomic and electrophysiological data.

problem Efficiently analyzing and visualizing paired multivariate neuroscientific data.
method Sparse deep neural networks with a two-dimensional bottleneck and group lasso penalty.
result Biologically interpretable two-dimensional visualizations of paired data.

Researchers use operator learning to predict cardiac activation and repolarization times.

problem Computational demands and need for clear, interpretable information in cardiac electrophysiology.
method Exploiting Fourier Neural Operators (FNO) and Kernel Operator Learning (KOL) to learn operator mappings.
result Both FNO and KOL approaches are computationally efficient and robust to hyperparameters.

Novel method embeds generative model into Bayesian optimization for HD cardiac model parameter estimation.

problem High-dimensional optimization of patient-specific cardiac model parameters with limited data.
method Embeds a generative variational auto-encoder into the objective function of Bayesian optimization.
result Improves accuracy of parameter estimation with more than 10x gain in efficiency.

This paper improves parameter estimation in cardiac models using Gaussian process-based MH sampling.

problem Uncertainty in estimating patient-specific model parameters from sparse and noisy clinical data.
method Integrates surrogate modeling into Metropolis-Hastings sampling to improve computational efficiency and accuracy.
result Significant gain in computational efficiency without compromising accuracy, and insights into tissue heterogeneity.

We consider the problem of locating a point-source heart arrhythmia using data from a standard diagnostic procedure, where a reference catheter is placed in the heart, and arrival times from a second diagnostic catheter are recorded as the diagnostic catheter moves around within the heart. We model this situation as a …

2018-07-09abs ↗pdf ↗

An electrocardiogram (EKG) is a common, non-invasive test that measures the electrical activity of a patient's heart. EKGs contain useful diagnostic information about patient health that may be absent from other electronic health record (EHR) data. As multi-dimensional waveforms, they could be modeled using generic mac…

2018-12-01abs ↗pdf ↗

Method extracts time-localized clusters to explain deep learning models in ECG analysis.

problem Limited understanding of deep learning models in ECG analysis.
method Extracts time-localized clusters from model's internal representations.
result Enhances trust in AI-driven diagnostics and reveals clinically relevant patterns.

Deep convolutional neural networks (CNNs) have demonstrated impressive performance on visual object classification tasks. In addition, it is a useful model for predication of neuronal responses recorded in visual system. However, there is still no clear understanding of what CNNs learn in terms of visual neuronal circu…

2017-11-08abs ↗pdf ↗

hyperSBINN improves drug cardiosafety assessment by efficiently modeling cardiac action potentials.

problem Complexity and limited data in modeling cardiac effects of drugs.
method Combining meta-learning with SBINNs to solve parameterized cardiac action potential models.
result hyperSBINN outperforms traditional solvers in speed and accuracy for predicting APD90 values.

Recent developments in high throughput profiling of individual neurons have spurred data driven exploration of the idea that there exist natural groupings of neurons referred to as cell types. The promise of this idea is that the immense complexity of brain circuits can be reduced, and effectively studied by means of i…

2019-11-06abs ↗pdf ↗

Develops a method to interpret deep learning models by identifying key features.

problem Revealing the decision-making process of blackbox models from raw data to predictions.
method Adversarial attacks to localize discriminative features with statistical guarantees.
result Locally identified features are both biologically plausible and statistically significant.

GAME improves matrix completion by considering subgroup-specific latent structures.

problem Heterogeneous data with overlapping categories, smoothing away subgroup-specific variation.
method Group-Aware Matrix Estimation (GAME) with overlapping nuclear-norm penalties.
result GAME outperforms global low-rank estimators in structured missingness regimes.

New method handles indirect mediators in CMA for complex scenarios.

problem Handling indirect and multi-dimensional mediators in causal mediation analysis.
method Identifiable Variational Autoencoder (iVAE) architecture for multi-dimensional, indirectly observed mediators.
result Accurate estimation of direct and mediated effects in synthetic and semi-synthetic experiments.

Classification of seizure type is a key step in the clinical process for evaluating an individual who presents with seizures. It determines the course of clinical diagnosis and treatment, and its impact stretches beyond the clinical domain to epilepsy research and the development of novel therapies. Automated identific…

2019-12-10abs ↗pdf ↗

The introduction of deep learning and transfer learning techniques in fields such as computer vision allowed a leap forward in the accuracy of image classification tasks. Currently there is only limited use of such techniques in neuroscience. The challenge of using deep learning methods to successfully train models in …

2019-07-02abs ↗pdf ↗

Framework for reconstructing nonlinear systems from multi-modal time series data.

problem Reconstructing nonlinear dynamical systems from multi-modal time series data.
method Dynamic interpretable recurrent neural networks coupled with generalized linear models for multi-modal data integration.
result Framework efficiently compensates for noisy or missing information in one data channel using other channels.

G-FuNK learns solutions for nonlinear PDEs on multiple domains and parameters.

problem Predicting time-dependent dynamics of complex systems governed by nonlinear PDEs with varying parameters and domains.
method Graph Fourier Neural Kernels combining domain-adapted and transferable components for non-diffusive and diffusive terms.
result G-FuNK achieves low relative errors on unseen domains and fiber fields, significantly accelerating predictions.

In recent years, the electrocardiogram (ECG) has seen a large diffusion in both medical and commercial applications, fueled by the rise of single-lead versions. Single-lead ECG can be embedded in medical devices and wearable products such as the injectable Medtronic Linq monitor, the iRhythm Ziopatch wearable monitor, …

2019-05-13abs ↗pdf ↗

SOS-VAE improves generative models for scientific applications by correcting decoder bias.

problem Bias in generative parameters due to supervised learning in VAEs.
method Develops SOS-VAE framework to influence decoder for predictive latent representation.
result Ensures reliable generative parameters for scientific applications.

Identifies learning rules from neural network observables.

problem Determine the underlying plasticity rules governing learning in biological systems.
method Simulated idealized neuroscience experiments with artificial neural networks to generate a dataset of learning trajectories. Used linear and non-linear classifiers to identify learning rules from aggregate statistics of weights, activations, and activity changes.
result Different classes of learning rules can be separated solely on the basis of aggregate statistics of the weights, activations, or instantaneous layer-wise activity changes.