Improved forecasting of suicide attempts using LSGPs for patients with little data.
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Efficiently fine-tunes patient-independent seizure detection models with tensor kernel machine.
Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress through disease stages at varying rates. This leads to pathophysiological misalig…
Deep learning clusters patient time-series data for better prognosis.
We develop a neural network model to classify liver cancer patients into high-risk and low-risk groups using genomic data. Our approach provides a novel technique to classify big data sets using neural network models. We preprocess the data before training the neural network models. We first expand the data using wavel…
The health outcomes of high-need patients can be substantially influenced by the degree of patient engagement in their own care. The role of care managers includes that of enrolling patients into care programs and keeping them sufficiently engaged in the program, so that patients can attain various goals. The attainmen…
FRESH combines patient-level and aggregate-level data for better clinical decision making.
Machine learning detects NASH patients from medical claims data.
Enhances causal estimation using unlabeled offline ICU data.
Proposes a framework for personalized treatment recommendations using observational data.
Patient journeys are compared to find clusters of similar disease trajectories.
Study proposes a model to improve patient subtyping from EHR data.
We develop a personalized real time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs. Heterogeneity of the patients population is captured via a hierarchical latent class model. The proposed algorithm aims t…
Model identifies key problems in HIV patients' records.
This paper presents a method for building patient-based networks that we call Precision disease networks, and its uses for predicting medical outcomes. Our methodology consists of building networks, one for each patient or case, that describes the dis-ease evolution of the patient (PDN) and store the networks as a set …
Study predicts risk of true-lumen narrowing after ATAAD surgery using CT data.
The introduction of data analytics into medicine has changed the nature of patient treatment. In this, patients are asked to disclose personal information such as genetic markers, lifestyle habits, and clinical history. This data is then used by statistical models to predict personalized treatments. However, due to pri…
Method infers TCR effects on disease using patient data.
Many computational models were proposed to extract temporal patterns from clinical time series for each patient and among patient group for predictive healthcare. However, the common relations among patients (e.g., share the same doctor) were rarely considered. In this paper, we represent patients and clinicians relati…
The paper tracks patient recovery using graphs of joint movement data.
We discovered secular trend bias in a drug effectiveness study for a recently approved drug. We compared treatment outcomes between patients who received the newly approved drug and patients exposed to the standard treatment. All patients diagnosed after the new drug's approval date were considered. We built a machine …
Alzheimer's disease (AD) is the most common neurodegenerative disease in older people. Despite considerable efforts to find a cure for AD, there is a 99.6% failure rate of clinical trials for AD drugs, likely because AD patients cannot easily be identified at early stages. This project investigated machine learning app…
Improving the quality of end-of-life care for hospitalized patients is a priority for healthcare organizations. Studies have shown that physicians tend to over-estimate prognoses, which in combination with treatment inertia results in a mismatch between patients wishes and actual care at the end of life. We describe a …
Model predicts wound and episode-level readmission risk and time to re-admit.
Multi-output Gaussian processes (GPs) are a flexible Bayesian nonparametric framework that has proven useful in jointly modeling the physiological states of patients in medical time series data. However, capturing the short-term effects of drugs and therapeutic interventions on patient physiological state remains chall…
Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative effectiveness research. One major carrier for conducting patient similarity resea…
Machine learning predicts trauma patient mortality risk.
In the scenario of real-time monitoring of hospital patients, high-quality inference of patients' health status using all information available from clinical covariates and lab tests is essential to enable successful medical interventions and improve patient outcomes. Developing a computational framework that can learn…
Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute coronary syndrome (ACS) is a syndrome due to sudden decrease of coronary artery blood f…
Visual summarization of clinical data collected on patients contained within the electronic health record (EHR) may enable precise and rapid triage at the time of patient presentation to an emergency department (ED). The triage process is critical in the appropriate allocation of resources and in anticipating eventual …
Deep learning model predicts severe COVID-19 outcomes.
Currently, approximately 30% of epileptic patients treated with antiepileptic drugs (AEDs) remain resistant to treatment (known as refractory patients). This project seeks to understand the underlying similarities in refractory patients vs. other epileptic patients, identify features contributing to drug resistance acr…
CLOCS uses contrastive learning to improve cardiac signal representations.
This paper presents an example of how demographical characteristics of patients influence their susceptibility to certain medical conditions. In this paper, we investigate the association of health conditions to age of patients in a heterogeneous population. We show that besides the symptoms a patients is having, the a…
Enhances understanding of patient healthcare journeys using self-attention.
Generative models create artificial patient data for distributed analysis.
This study addresses the issue of predicting the glaucomatous visual field loss from patient disease datasets. Our goal is to accurately predict the progress of the disease in individual patients. As very few measurements are available for each patient, it is difficult to produce good predictors for individuals. A rece…
A new model improves homogeneity in burn patient reimbursement.
Framework predicts patient risk progression over time.
Digital Adherence Technologies (DATs) are an increasingly popular method for verifying patient adherence to many medications. We analyze data from one city served by 99DOTS, a phone-call-based DAT deployed for Tuberculosis (TB) treatment in India where nearly 3 million people are afflicted with the disease each year. T…
Deep learning model creates patient representations for scalable EHR-based stratification.
Rare diseases affecting 350 million individuals are commonly associated with delay in diagnosis or misdiagnosis. To improve those patients' outcome, rare disease detection is an important task for identifying patients with rare conditions based on longitudinal medical claims. In this paper, we present a deep learning m…
The behaviors of patients with depression are usually difficult to predict because the patients demonstrate the symptoms of a depressive episode without a warning at unexpected times. The goal of this research is to build algorithms that detect signals of such unusual moments so that doctors can be proactive in approac…
Paper shows Cox model optimisation leaks patient data in distributed learning.
Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia - high blood glucose (BG). Patients must also be careful not to inject too much insulin because this could induce hypoglycemia (low BG), which can potentially be fatal. Patients therefore follow a …
Deep CNN-RNN model classifies breathing sounds for respiratory disease diagnosis.
VBphenoR uses variational Bayes for EHR-based patient phenotyping.
Artificial Intelligence in healthcare is a new and exciting frontier and the possibilities are endless. With deep learning approaches beating human performances in many areas, the logical next step is to attempt their application in the health space. For these and other Machine Learning approaches to produce good resul…