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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,742 papers · 148 categories

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52104155207 · May 202619922001200920172026
48 results for pathological complete response

Deep learning predicts response to HER2-targeted breast cancer therapy.

problem Predicting response to HER2-targeted neoadjuvant chemotherapy.
method Developed and validated a deep learning approach using pre-treatment dynamic breast MRI.
result Deep learning model achieved strong performance in predicting pathological complete response.

Many people are suffering from voice disorders, which can adversely affect the quality of their lives. In response, some researchers have proposed algorithms for automatic assessment of these disorders, based on voice signals. However, these signals can be sensitive to the recording devices. Indeed, the channel effect …

2018-11-26abs ↗pdf ↗

Improved hypernetwork for efficient neural network hyperparameter tuning.

problem Efficiently optimizing hyperparameters in neural networks.
method Proposed ΔΔ-STN architecture focusing on accurate best-response Jacobian approximation.
result Significantly improved hyperparameter tuning accuracy and stability.

This study investigates how much knowledge from natural images can be transferred to pathology images.

problem Quantifying how much knowledge from natural images can be transferred to pathology images.
method Proposes a framework to quantify knowledge gain by a particular layer, conducts empirical investigation in pathology image centered transfer learning.
result Early layers of deep models can transfer knowledge to pathology image classification tasks.

Exploratory cancer drug studies test multiple tumor cell lines against multiple candidate drugs. The goal in each paired (cell line, drug) experiment is to map out the dose-response curve of the cell line as the dose level of the drug increases. We propose Bayesian Tensor Filtering (BTF), a hierarchical Bayesian model …

2019-06-10abs ↗pdf ↗

This paper characterizes VAE training pathologies and their effects on tasks.

problem Characterizing VAE training pathologies and their impact on downstream tasks.
method Concretely characterizing conditions for VAE training pathologies and their connection to specific downstream tasks.
result Connects VAE training pathologies to specific downstream tasks like learning compressed and disentangled representations, adversarial robustness, and semi-supervised learning.

A Pathology report is arguably one of the most important documents in medicine containing interpretive information about the visual findings from the patient's biopsy sample. Each pathology report has a retention period of up to 20 years after the treatment of a patient. Cancer registries process and encode high volume…

2019-03-05abs ↗pdf ↗

KL-regularized RL from expert demos can lead to slow, unstable learning.

problem Pathological training dynamics in KL-regularized RL from expert demonstrations.
method Empirical analysis and non-parametric behavioral reference policies.
result KL-regularized RL can be significantly improved by using non-parametric behavioral policies.

Deployment-complete benchmarking assesses if evidence leads to consistent deployment actions.

problem Lack of clear evidence leading to consistent deployment actions.
method Introduces deployment-complete benchmarking to test if benchmark evidence determines deployment actions.
result Benchmark evidence must be complete for a claim to lead to a consistent deployment action.

We introduce a novel approach, requiring only mild assumptions, for the characterization of deep neural networks at initialization. Our approach applies both to fully-connected and convolutional networks and easily incorporates batch normalization and skip-connections. Our key insight is to consider the evolution with …

2018-11-07abs ↗pdf ↗

Chronic Pulmonary Aspergillosis (CPA) is a complex lung disease caused by infection with Aspergillus. Computed tomography (CT) images are frequently requested in patients with suspected and established disease, but the radiological signs on CT are difficult to quantify making accurate follow-up challenging. We propose …

2019-02-06abs ↗pdf ↗

The paper presents algorithms for diagnosing Pathological Myopia and detecting retinal structures.

problem Diagnosing Pathological Myopia and detecting retinal structures in fundus images.
method The approach uses Deep Learning techniques, including transfer learning with Xception and YOLO architecture.
result The method has shown satisfactory results in the Pathologic Myopia Challenge.

New analysis explains pathology of deep Gaussian processes.

problem Pathology of deep Gaussian processes reduces learning capacities with increased layers.
method Study nonlinear dynamic systems corresponding to DGPs, derive recurrence relations.
result Provide tighter bounds and rate of convergence for dynamic systems.

Causal methods for GRN inference from single-cell data often fail in real-world benchmarks.

problem Understanding when and why causal methods for GRN inference from single-cell data fail in real-world benchmarks.
method Introduced a controlled diagnostic framework to isolate and measure seven pathologies.
result Causal methods dominate in clean and structurally favorable regimes but fail in specific pathologies.

Segmentation of anatomical structures and pathologies is inherently ambiguous. For instance, structure borders may not be clearly visible or different experts may have different styles of annotating. The majority of current state-of-the-art methods do not account for such ambiguities but rather learn a single mapping f…

2019-06-07abs ↗pdf ↗

For test configurations, the Donaldson-Futaki invariant F_1 is well-known. In this note, its refinement will be discussed. Then we see that Li-Xu's pathology doesn't occur, since their example of a non-normal test configuration, with trivial normalization, actually has non-vanishing F_1 in this refined sense.

2013-05-28abs ↗pdf ↗

New test identifies specific biological parameters for personalized CVD detection.

problem Ineffectual pathology tests fail to consider platelet activation and inter-individual variability.
method Stochastic platelet deposition model and approximate Bayesian computation with discriminative summary statistics.
result Inferred parameters help identify specific biological parameters for personalized CVD detection.

This paper proposes synthetic augmentation for nuclei image segmentation in medical pathology.

problem Rare and time-consuming labeling of tumor nuclei images for semantic segmentation.
method Label-to-image translation to generate synthetic images.
result Synthetic augmentation improves segmentation accuracy.

Aim: To review how machine learning (ML) is applied to imaging biomarkers in neuro-oncology, in particular for diagnosis, prognosis, and treatment response monitoring. Materials and Methods: The PubMed and MEDLINE databases were searched for articles published before September 2018 using relevant search terms. The sear…

2019-08-28abs ↗pdf ↗

Automatic Chemical Design is a framework for generating novel molecules with optimized properties. The original scheme, featuring Bayesian optimization over the latent space of a variational autoencoder, suffers from the pathology that it tends to produce invalid molecular structures. First, we demonstrate empirically …

2017-09-16abs ↗pdf ↗

Pathology reports contain useful information such as the main involved organ, diagnosis, etc. These information can be identified from the free text reports and used for large-scale statistical analysis or serve as annotation for other modalities such as pathology slides images. However, manual classification for a hug…

2019-10-31abs ↗pdf ↗

Pseudo healthy synthesis, i.e. the creation of a subject-specific `healthy' image from a pathological one, could be helpful in tasks such as anomaly detection, understanding changes induced by pathology and disease or even as data augmentation. We treat this task as a factor decomposition problem: we aim to separate wh…

2019-01-10abs ↗pdf ↗

The recently proposed SPARse Factor Analysis (SPARFA) framework for personalized learning performs factor analysis on ordinal or binary-valued (e.g., correct/incorrect) graded learner responses to questions. The underlying factors are termed "concepts" (or knowledge components) and are used for learning analytics (LA),…

2014-12-18abs ↗pdf ↗

Missing responses is a missing data format in which outcomes are not always observed. In this work we develop kernel machines that can handle missing responses. First, we propose a kernel machine family that uses mainly the complete cases. For the quadratic loss, we then propose a family of doubly-robust kernel machine…

2018-06-07abs ↗pdf ↗

We propose a new model for digital pathology segmentation, based on the observation that histopathology images are inherently symmetric under rotation and reflection. Utilizing recent findings on rotation equivariant CNNs, the proposed model leverages these symmetries in a principled manner. We present a visual analysi…

2018-06-08abs ↗pdf ↗

Boosted additive models reveal new insights and potential pathologies.

problem Theoretical understanding of boosted additive models (BAMs) and their convergence behavior.
method Study of solution paths of BAMs and derivation of convergence results.
result Uncovering pathologies of boosting for certain additive model classes.

Dropout, a stochastic regularisation technique for training of neural networks, has recently been reinterpreted as a specific type of approximate inference algorithm for Bayesian neural networks. The main contribution of the reinterpretation is in providing a theoretical framework useful for analysing and extending the…

2018-07-05abs ↗pdf ↗

The study optimizes sampling in complex systems with probabilistic response distributions.

problem Calibrating and optimizing complex systems with probabilistic response distributions.
method Non-parametric Bayesian approach to modeling spatial fields of probability distributions, introducing adaptive sampling strategies.
result Adaptive sampling strategies improve system evaluations by guiding focus towards key features.

The study uses response theory to understand RNNs processing input signals.

problem Understanding how RNNs process sequential data.
method Deriving a Volterra series representation for SRNNs output using response theory from nonequilibrium statistical mechanics.
result SRNNs can be viewed as kernel machines operating on a reproducing kernel Hilbert space associated with the response feature.