Paper introduces ps-BART for estimating nonlinear ATE and CATE in continuous treatments.
problem Estimating ATE and CATE in continuous treatments with nonlinear relationships.
method Generalized ps-BART model for nonparametric estimation.
result ps-BART outperforms BCF model in highly nonlinear settings.
Proposes TSCI method to infer causal effects with weak or invalid instruments using machine learning.
problem Causal inference with weak or invalid instrumental variables.
method Two-stage curvature identification (TSCI) using machine learning.
result Asymptotically unbiased and Gaussian estimator for causal effects.
Proposes CoDEAL for estimating heterogeneous treatment effects in panel data models.
problem Estimating heterogeneous treatment effects in causal panel data models with covariate effects.
method Covariate-Adjusted Deep Causal Learning (CoDEAL) integrating neural networks and autoencoders.
result Establishes theoretical guarantees and demonstrates compelling performance in simulations and real data.
DFIV uses deep neural nets to learn nonlinear features in IV regression.
problem Learning causal relationships from observational data with nonlinear interactions.
method DFIV trains deep neural nets to define nonlinear features on instruments and treatments, alternating training to compose stages 1 and 2.
result DFIV outperforms state-of-the-art methods on IV benchmarks and off-policy policy evaluation.
New boundary treatment improves accuracy for complex PDEs.
problem Order reduction in high-order IMEX schemes for multidimensional PDEs.
method Novel boundary treatment algorithms for Cartesian meshes, treating implicit-explicit stages similarly to interior points.
result Recovery of designed order of convergence by numerical verification.
Optimal biomarker combinations for treatment-selection can be derived by minimizing total burden to the population caused by the targeted disease and its treatment. However, when multiple biomarkers are present, including all in the model can be expensive and hurt model performance. To remedy this, we consider feature …
DFPV improves PCL for confounded bandit policy evaluation.
problem Estimating causal effects in confounded settings with high-dimensional data.
method Deep feature proxy variable method (DFPV) for high-dimensional, nonlinear relationships.
result DFPV outperforms state-of-the-art methods on synthetic benchmarks and confounded bandit problems.
Develops a method for causal inference with noisy confounders.
problem Noisy measurements of confounders in treatment effects models.
method Local principal subspace approximation combining K-nearest neighbors matching and PCA.
result Estimators of treatment effects and counterfactual distributions are constructed.
G-Net uses deep learning for complex counterfactual outcome prediction.
problem Estimating counterfactual outcomes under dynamic treatment strategies.
method G-Net is a sequential deep learning framework for G-computation.
result G-Net can handle complex temporal data and provide accurate treatment effects.
BGM-IV uses AI to estimate causal effects in complex data.
problem Estimating causal effects in high-dimensional, nonlinear settings with endogeneity.
method Structured latent generative modeling for posterior inference in a causally structured latent space.
result BGM-IV outperforms existing methods in high-dimensional covariate regimes.
In many compressive sensing problems today, the relationship between the measurements and the unknowns could be nonlinear. Traditional treatment of such nonlinear relationships have been to approximate the nonlinearity via a linear model and the subsequent un-modeled dynamics as noise. The ability to more accurately ch…
TSCI estimates treatment effects using machine learning and data-adaptive methods for invalid instruments.
problem Estimating treatment effects with invalid instruments.
method Two-stage algorithm: first stage uses machine learning for nonlinearities, second stage selects and projects out instrument violations.
result Effective treatment effect estimation even with invalid instruments.
Framework improves health by planning actionable treatment processes.
problem Developing objective treatment processes in clinical settings.
method Surrogate Bayesian model combined with ML for personalized health improvement.
result Computed treatment processes are actionable and consistent with clinical knowledge.
Method for understanding heterogeneous treatment effects in complex causal graphs.
problem Heterogeneity and comorbidity in healthcare problems.
method Developed a new approach to characterize heterogeneous causal effects (HCEs) in graphical contexts, including heterogeneous causal graphs (HCGs) with confounders and mediators.
result Established theoretical forms and properties of HCEs in linear and nonlinear models, and developed interactive structural learning for estimation.
We develop a prediction-based prescriptive model for learning optimal personalized treatments for patients based on their Electronic Health Records (EHRs). Our approach consists of: (i) predicting future outcomes under each possible therapy using a robustified nonlinear model, and (ii) adopting a randomized prescriptiv…
Medical practitioners use survival models to explore and understand the relationships between patients' covariates (e.g. clinical and genetic features) and the effectiveness of various treatment options. Standard survival models like the linear Cox proportional hazards model require extensive feature engineering or pri…
ICA accurately estimates treatment effects even with confounders.
problem Estimating treatment effects in the presence of confounding variables.
method Uses Independent Component Analysis (ICA) to identify latent sources and estimate mixing coefficients.
result Linear ICA can consistently estimate multiple treatment effects, even with Gaussian confounders, and is more sample-efficient than Orthogonal Machine Learning (OML).
MediEncoder learns nonlinear representations for causal mediation analysis.
problem High-dimensional noisy covariates and mediators in biomedical studies.
method Coupled encoder-decoder architecture with cross-factor network.
result Improves estimation accuracy in high-dimensional causal mediation analysis.
CausalLongPFN predicts counterfactual outcomes from time-series data.
problem Predicting future outcomes under varying treatments in time-series data with confounding and heterogeneity.
method Prior-fitted network pretrained on synthetic episodes of temporal structural causal models.
result CausalLongPFN outperforms domain-trained models on factual and counterfactual prediction tasks.
Study proposes method to estimate causal effects from noisy treatment data.
problem Estimating causal effects from noisy treatment data without side information.
method Deep latent variable model with neural network parameterization and amortized importance-weighted variational objective.
result Causal effect estimates are identifiable without side information and measurement error variance knowledge.
The paper introduces a new model to correct bias in treatment effect estimates due to sample selection.
problem Bias in treatment effect estimates due to sample selection.
method Type 2 Tobit Bayesian Additive Regression Trees (TOBART-2) with Dirichlet Process Mixture distribution and soft trees.
result Corrects bias in treatment effect estimates by accounting for nonlinearities and model uncertainty.
We present a new machine learning approach to estimate personalized treatment effects in the classical potential outcomes framework with binary outcomes. To overcome the problem that both treatment and control outcomes for the same unit are required for supervised learning, we propose surrogate loss functions that inco…
We present nonparametric algorithms for estimating optimal individualized treatment rules. The proposed algorithms are based on the XGBoost algorithm, which is known as one of the most powerful algorithms in the machine learning literature. Our main idea is to model the conditional mean of clinical outcome or the decis…
Proposes estimators for complex dose-response curves using kernel methods.
problem Estimating complex dose-response curves with continuous treatments, mediators, and covariates.
method Kernel ridge regression with sequential kernel embedding technique.
result Simple estimators for mediated and time-varying dose response curves with nonasymptotic uniform rates.
FSRM method improves treatment effect estimation from observational data.
problem Estimating treatment effects from observational data with missing counterfactual outcomes and selection bias.
method FSRM method based on deep representation learning and matching, which maps covariate space into a selective, nonlinear, and balanced representation space.
result FSRM method outperforms state-of-the-art methods in estimating treatment effects.
The paper uses deep neural networks to estimate and infer ATE without needing to know the dimension of the data.
problem Estimating and inferring the average treatment effect (ATE) in complex data settings.
method The paper uses deep neural networks to estimate the mean regression function and then calculates the ATE. It establishes consistency and asymptotic normality of the estimators.
result The deep neural network estimates of ATE are consistent and asymptotically normal, providing dimension-free rates.
The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who are more prone to adverse outcomes after an initial synthetic opioid prescription…
Study uses exchangeable GPs for staggered-adoption policy evaluation in panel data.
problem Evaluating the impact of staggered treatments in panel data settings.
method Exchangeable multi-task Gaussian processes (GPs) with flexible kernels.
result Flexible tool for policy evaluation in panel data settings.
Machine Learning improves macroeconomic forecasting by capturing nonlinearities.
problem Improving macroeconomic forecasting accuracy.
method Study four features (nonlinearities, regularization, cross-validation, loss function) in data-rich and data-poor environments.
result Nonlinearity is the key to improving forecasting accuracy.
Paper develops a new estimator for panel data with endogenous treatments, improving causal inference.
problem Challenges in causal inference for static panel data with endogenous treatments and confounding variables.
method Develops Double Machine Learning (DML) estimator for static panel models with endogenous treatments (panel IV DML). Introduces weak-identification diagnostics.
result Panel IV DML estimator improves estimation accuracy and delivers more reliable inference under weak identification.
BINDy uses Bayesian methods to identify nonlinear dynamics from data.
problem Learning sparse representations of complex dynamics from data.
method Bayesian treatment of dictionary learning system identification using reversible-jump Markov-chain Monte-Carlo.
result BINDy produces models that are sparse in model space rather than parameter space.
We present examples of agent-based and stochastic models of competition and business processes in economics and finance. We start from as simple as possible models, which have microscopic, agent-based, versions and macroscopic treatment in behavior. Microscopic and macroscopic versions of herding model proposed by Kirm…
Estimates effects of multiple interventions with hidden confounders using single-variable interventions.
problem Estimating effects of multiple interventions in the presence of hidden confounders.
method Identifiability under nonlinear structural causal model with additive Gaussian noise; pooling and joint likelihood maximization.
result Proven identifiability and superior performance compared to baseline.
FIDDLE uses deep learning to estimate ATE from complex data.
problem Estimating ATE from high-dimensional, correlated covariates with sparse nonlinear effects.
method Factor-augmented deep learning for propensity and outcome models.
result FIDDLE consistently estimates ATE under model misspecification and is semiparametrically efficient.
Bayesian framework improves survival prediction accuracy and uncertainty quantification.
problem Inaccurate uncertainty estimates in survival models.
method Bayesian framework combining variational inference, neural multi-task logistic regression, and sparsity-inducing prior.
result Better quantification of survival uncertainty and more accurate predictions.
Achilles Tendon Rupture (ATR) is one of the typical soft tissue injuries. Rehabilitation after such a musculoskeletal injury remains a prolonged process with a very variable outcome. Accurately predicting rehabilitation outcome is crucial for treatment decision support. However, it is challenging to train an automatic …
The paper automates policy learning for nonlinear welfare criteria using machine learning and debiasing techniques.
problem Learning optimal policies from observational data with nonlinear welfare criteria.
method Modeling a nonlinear welfare criterion with a utility function, estimating propensity scores with machine learning, and using sieve approximations and cross-validation for model selection.
result The proposed policy learning method satisfies oracle inequalities, providing theoretical guarantees on performance.
MOCA uses modular attention to estimate causal effects from complex data.
problem Estimating causal effects from observational data with complex, non-linear, and high-dimensional treatment and outcome mechanisms.
method MOCA is a transformer-based framework that separates treatment and outcome modeling through modular design and one-way attention mechanism, with cutting-feedback to prevent outcome influence on treatment representations.
result MOCA outperforms classical estimators and machine learning approaches across various simulated and real-world scenarios.
New technologies for recording the activity of large neural populations during complex behavior provide exciting opportunities for investigating the neural computations that underlie perception, cognition, and decision-making. Nonlinear state space models provide an interpretable signal processing framework by combinin…
DCMA uses generative models to analyze treatment effects on entire outcome distributions.
problem Traditional mediation analysis focuses on summary contrasts, missing complex distributional changes.
method DCMA learns conditional generative models for mediators and outcome, reconstructing interventional distributions via Monte Carlo simulation.
result DCMA captures both summary effects and rich distributional contrasts like energy distance and Wasserstein distance.
DCMA uses generative models to analyze complex treatment effects on outcome distributions.
problem Analyzing complex and nonlinear causal mechanisms through outcome-level summary contrasts.
method Generative learning framework for identifying and estimating treatment effects on entire outcome distributions.
result Reconstructs interventional outcome distributions via Monte Carlo forward simulation, capturing both summary and distributional contrasts.
DIV estimates entire interventional distribution using generative modeling.
problem Estimating entire interventional distribution in presence of unmeasured confounding.
method Distributional Instrumental Variable (DIV) using generative modeling.
result DIV identifies causal effects under 'under-identified' cases, improving over existing IV approaches.
Proposes a new Q-learning method for survival outcomes in clinical trials.
problem Incomplete follow-up data and nonlinear covariate effects in clinical trials.
method Combines Buckley-James boosting with flexible base learners for estimating optimal treatment regimes.
result Improves treatment decision accuracy and stability in longitudinal clinical trials.
Method estimates causal effects from combined interventional and observational data.
problem Estimating causal effects from unobserved confounders.
method Causal reduction method replacing latent confounders with a single latent confounder.
result Improves estimation accuracy from combined data without observing all confounders.
Modeling financial chaos with market makers' risk appetite.
problem Unpredictable price changes in financial markets.
method Using Hamiltonian approach with anharmonic oscillators and nonlinear coupling.
result Market makers' risk appetite determines chaotic dynamics in financial markets.
In this paper, we present a generic framework to extend existing uniformly optimal convex programming algorithms to solve more general nonlinear, possibly nonconvex, optimization problems. The basic idea is to incorporate a local search step (gradient descent or Quasi-Newton iteration) into these uniformly optimal conv…
EB-VAE combines tumor growth and dropout data for personalized treatment response modeling.
problem Challenges in integrating longitudinal tumor measurements, dropout information, and genetic covariates.
method Extended EB-VAE framework to jointly model longitudinal and time-to-event data, incorporating dropout hazard and genetic covariates.
result Hybrid decoder formulation yields consistent treatment-effect parameters and prior predictive performance comparable to neural decoder.
Machine learning (ML) is shown to predict new alloys and their performances in a high dimensional, multiple-target-property design space that considers chemistry, multi-step processing routes, and characterization methodology variations. A physics-informed featured engineering approach is shown to enable otherwise poor…