Study examines how classifier performance is affected by training data quality.
arXiv research
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Paper uses genome Markov structure for outlier detection and read classification.
Metagenomic studies have increasingly utilized sequencing technologies in order to analyze DNA fragments found in environmental samples.One important step in this analysis is the taxonomic classification of the DNA fragments. Conventional read classification methods require large databases and vast amounts of memory to…
We introduce GeNet, a method for shotgun metagenomic classification from raw DNA sequences that exploits the known hierarchical structure between labels for training. We provide a comparison with state-of-the-art methods Kraken and Centrifuge on datasets obtained from several sequencing technologies, in which dataset s…
Metagenomics characterizes the taxonomic diversity of microbial communities by sequencing DNA directly from an environmental sample. One of the main challenges in metagenomics data analysis is the binning step, where each sequenced read is assigned to a taxonomic clade. Due to the large volume of metagenomics datasets,…
New algorithm estimates intrinsic dimension of discrete datasets.
New algorithm optimizes matrix reordering for noisy disordered matrices.
The tremendous boost in the next generation sequencing and in the omics technologies makes it possible to characterize human gut microbiome (the collective genomes of the microbial community that reside in our gastrointestinal tract). While some of these microorganisms are considered as essential regulators of our immu…
For every strong coarse homology theory we construct a coarse assembly map as a natural transformation between coarse homology theories. We provide various conditions implying that this assembly map is an equivalence. These results generalize known results for the analytic coarse assembly map for K-homology to general …
Model predicts composite structures assembly quality with input uncertainty.
Survey on metrics and assembly maps in positive scalar curvature.
If a Lie algebra structures $\gG$ on a vector space is the sum of a family of mutually compatible Lie algebra structures $\gG_i$, we say that $\gG$ is \emph{simply assembled} from $\gG_s$'s. By repeating this procedure several times one gets a family of Lie algebras \emph{assembled} from $\gG_s$'s. The central result o…
We construct the geometric Baum-Connes assembly map for twisted Lie groupoids, that means for Lie groupoids together with a given groupoid equivariant principle bundle. The construction is based on the use of geometric deformation groupoids, these objects allow in particular to give a geometric construction of …
We study in this paper the maximal version of the coarse Baum-Connes assembly map for families of expanding graphs arising from residually finite groups. Unlike for the usual Roe algebra, we show that this assembly map is closely related to the (maximal) Baum-Connes assembly map for the group and is an isomorphism for …
Realistic evolutionary fitness landscapes are notoriously difficult to construct. A recent cutting-edge model of virus assembly consists of a dodecahedral capsid with corresponding packaging signals in three affinity bands. This whole genome/phenotype space consisting of genomes has been explored via comp…
Controlled -theory is used to show that algebraic -theory of virtually abelian groups is described by an assembly map defined using possibly-infinite hyperelementary subgroups. The Farrell-Jones summand (coming from infinite subgroups) is parameterized by the rational projective space of the group, and a reduced …
If a Lie algebra structure g on a vector space is the sum of a family of mutually compatible Lie algebra structures g_i's, we say that g is simply assembled from the g_i's. Repeating this procedure with a number of Lie algebras, themselves simply assembled from the g_i's, one obtains a Lie algebra assembled in two step…
We use assembly maps to study , the topological cyclic homology at a prime of the group algebra of a discrete group with coefficients in a connective ring spectrum . For any finite group, we prove that the assembly map for the family of cyclic subgroups is an isomorphis…
Convolutional Neural Networks (CNNs) are a popular deep learning architecture widely applied in different domains, in particular in classifying over images, for which the concept of convolution with a filter comes naturally. Unfortunately, the requirement of a distance (or, at least, of a neighbourhood function) in the…
A framework for generating 3D shapes by sequentially assembling primitives.
In this article, we introduce the notion of a functor on coarse spaces being coarsely excisive- a coarse analogue of the notion of a functor on topological spaces being excisive. Further, taking cones, a coarsely excisive functor yields a topologically excisive functor, and for coarse topological spaces there is an ass…
Defines and computes geometric pairings for discrete groups using Baum-Connes assembly map.
Model for assembly map of bordism-invariant functors.
We analyze linear independence of rank one tensors produced by tensor powers of randomly perturbed vectors. This enables efficient decomposition of sums of high-order tensors. Our analysis builds upon [BCMV14] but allows for a wider range of perturbation models, including discrete ones. We give an application to recove…
We construct a higher Whitehead torsion map, using algebraic K-theory of spaces, and show that it satisfies the usual properties of the classical Whitehead torsion. This is used to describe a "geometric assembly map" defined on stabilized structure spaces in purely homotopy theoretic terms.
Model detects patterns in noisy binary data, explaining neuron activity in terms of cell assemblies.
In this paper, we propose a semi-supervised deep learning method for detecting the specific types of reads that impede the de novo genome assembly process. Instead of dealing directly with sequenced reads, we analyze their coverage graphs converted to 1D-signals. We noticed that specific signal patterns occur in each r…
Easy-to-assemble 3D model of Boy's surface.
In this paper we introduce a homotopy theoretic technique for proving that the -theoretic assembly map is an equivalence. It is an extension of the methods used to prove split injectivity of the assembly and applies to any geometrically finite group. Our result is that there are two requirements which need to hold. …
Bayesian calibration for BCP self-assembly models using image data and measure transport.
Between the category of exact metric spaces with bounded geometry (about which much is known) and the larger category of arbitrary exact metric spaces (about which little is known) lies the intermediate category of asymptotically exact metric spaces. We show that the coarse Baum-Connes assembly map is naturally split s…
Deep neural networks (DNNs) are known for extracting useful information from large amounts of data. However, the representations learned in DNNs are typically hard to interpret, especially in dense layers. One crucial issue of the classical DNN model such as multilayer perceptron (MLP) is that neurons in the same layer…
In this paper, the first of a series of two, we continue the study of higher index theory for expanders. We prove that if a sequence of graphs is an expander and the girth of the graphs tends to infinity, then the coarse Baum-Connes assembly map is injective, but not surjective, for the associated metric space . Exp…
This paper provides a full controlled version of algebraic -theory. This includes a rich array of assembly maps; the controlled assembly isomorphism theorem identifying the controlled group with homology; and the stability theorem describing the behavior of the inverse limit as the control parameter goes to 0. There…
We prove that the Farrell-Jones assembly map for connective algebraic K-theory is rationally injective, under mild homological finiteness conditions on the group and assuming that a weak version of the Leopoldt-Schneider conjecture holds for cyclotomic fields. This generalizes a result of Bökstedt, Hsiang, and Madsen, …
Study uses multi-agent reinforcement learning to control self-assembly with high-resolution external control.
Analyzes semi-characteristics on specific manifolds, proving a vanishing theorem.
Let M be a hyperkähler manifold. The S^2-family of complex structures compatible with the hyperkähler metric can be assembled into a single complex structure on Z=MxS^2; the resulting complex manifold is known as the twistor space of M. We describe the analogous construction for generalized complex structures in the se…
CHANI learns classification tasks with local transformations inspired by biology.
Defines Whitehead torsion for topological spaces via K-theory.
A geometric model for twisted -homology is introduced. It is modeled after the Mathai-Melrose-Singer fractional analytic index theorem in the same way as the Baum-Douglas model of -homology was modeled after the Atiyah-Singer index theorem. A natural transformation from twisted geometric -homology to the new g…
Study geometry of tetrahedra in complex hyperbolic space and Hilbert spaces.
Contemporary sensorimotor learning approaches typically start with an existing complex agent (e.g., a robotic arm), which they learn to control. In contrast, this paper investigates a modular co-evolution strategy: a collection of primitive agents learns to dynamically self-assemble into composite bodies while also lea…
We give a new proof of an index theorem for fiber bundles of compact topological manifolds due to Dwyer, Weiss, and Williams, which asserts that the parametrized -theory characteristic of such a fiber bundle factors canonically through the assembly map of -theory. Furthermore our main result shows a refinement of…
This paper explores topological aspects of index theory for infinite-dimensional manifolds.
A critical decision point when training predictors using multiple studies is whether studies should be combined or treated separately. We compare two multi-study prediction approaches in the presence of potential heterogeneity in predictor-outcome relationships across datasets: 1) merging all of the datasets and traini…
In this paper, the second of a series of two, we continue the study of higher index theory for expanders. We prove that if a sequence of graphs has girth tending to infinity, then the maximal coarse Baum-Connes assembly map is an isomorphism for the associated metric space . As discussed in the first paper in this s…
We prove that any countable discrete and torsion free subgroup of a general linear group over an arbitrary field or a similar subgroup of an almost connected Lie group satisfies the integral algebraic K-theoretic (split) Novikov conjecture over \cpt and §, where \cpt denotes the C^*-algebra of compact operators and §de…