DEBIAS learns causal effects from psychiatric longitudinal data by optimizing outcome weights.
problem Causal inference challenges in psychiatric longitudinal data due to symptom heterogeneity and latent confounding.
method DEBIAS algorithm that optimizes outcome weights to maximize durable treatment effects and minimize confounding.
result DEBIAS consistently outperforms state-of-the-art methods in recovering causal effects for clinically interpretable composite outcomes.
Develops a new density ratio estimator for causal inference.
problem Estimation of density ratio functions in statistics.
method Super learning approach with a novel loss function.
result Empirical validation of the density ratio super learner's performance.
Develops a deep survival model for causal inference in longitudinal studies.
problem Estimating treatment effects on time-to-event outcomes in observational studies with time-dependent covariates.
method TCS model using potential outcomes framework and ensemble of recurrent subnetworks.
result Identifies conditional average treatment effects and individual treatment effect heterogeneity over time.
C-kNN-LSH identifies similar patient histories for causal inference in longitudinal data.
problem Estimating causal effects from longitudinal trajectories with high-dimensional confounding.
method C-kNN-LSH uses locality-sensitive hashing to find clinical twins and estimate treatment effects.
result C-kNN-LSH outperforms existing methods in capturing recovery heterogeneity and estimating policy values.
CausalLongPFN predicts counterfactual outcomes from time-series data.
problem Predicting future outcomes under varying treatments in time-series data with confounding and heterogeneity.
method Prior-fitted network pretrained on synthetic episodes of temporal structural causal models.
result CausalLongPFN outperforms domain-trained models on factual and counterfactual prediction tasks.
Develops methods for causal inference in longitudinal data.
problem Estimating Individual Treatment Effects (ITEs) in high-dimensional, time-varying data.
method Causal Dynamic Variational Autoencoder (CDVAE) and long-term counterfactual regression framework.
result CDVAE outperforms baselines and improves state-of-the-art models, approaching oracle performance.
Develops a Causal Transformer for estimating counterfactual outcomes from longitudinal data.
problem Estimating counterfactual outcomes over time from observational data is challenging due to complex, long-range dependencies.
method Combines three transformer subnetworks with separate inputs for time-varying covariates, previous treatments, and previous outcomes into a joint network with in-between cross-attentions. Uses a custom, end-to-end training procedure with a counterfactual domain confusion loss to address confounding bias.
result Achieves superior performance over current baselines in synthetic and real-world datasets.
CDM models counterfactual outcomes in longitudinal data with improved accuracy.
problem Predicting counterfactual outcomes in longitudinal data with complex time-dependent confounding.
method Causal Diffusion Model (CDM) using denoising diffusion architecture with relational self-attention.
result CDM outperforms state-of-the-art methods in generating full probabilistic distributions of counterfactual outcomes.
DR-FRL learns functional states from irregular histories for causal inference.
problem Causal inference with irregularly sampled longitudinal data.
method DR-FRL workflow combining functional and temporal encoders, nuisance heads, and EIF-targeted validation.
result DR-FRL can improve causal inference when pseudo-outcomes are heavy-tailed or measurement is informative.
Causal processes in biomedicine may contain cycles, evolve over time or differ between populations. However, many graphical models cannot accommodate these conditions. We propose to model causation using a mixture of directed cyclic graphs (DAGs), where the joint distribution in a population follows a DAG at any single…
Causal Imitation Learning handles noisy measurements and distribution shifts.
problem Learning from noisy state observations and distributional shifts.
method Causal inference framework and adversarial RKHS learning.
result Improved robustness to distribution shifts compared to standard methods.
CDVAE estimates treatment effects over time by accounting for unobserved variables.
problem Estimating treatment effects over time in the presence of unobserved confounders.
method Causal Dynamic Variational Autoencoder (CDVAE) that addresses unconfoundedness and unobserved heterogeneity.
result CDVAE outperforms existing methods in estimating Conditional Average Treatment Effects (CATEs).
Bayesian Causal Forests model assesses part-time work's impact on student growth.
problem Estimating causal effects of part-time work on student growth in mathematics achievement.
method Longitudinal Bayesian Causal Forests model combining non-parametric and difference-in-differences methods.
result Negative impact of part-time work for most students, potential benefits for those with low school belonging, widening achievement gap identified.
Develops methods to identify and estimate causal effects with instrumental variables.
problem Causal inference with confounded treatment assignment and unobserved variables.
method General nonparametric causal framework, debiased machine learning, semiparametric theory.
result Consistent and asymptotically normal estimators for average treatment effect.
TV-SurvCaus improves causal inference for dynamic treatments in survival analysis.
problem Estimating causal effects of time-varying treatments on survival outcomes.
method Representation balancing techniques extended to time-varying treatment regimes with survival outcomes.
result TV-SurvCaus outperforms existing methods in estimating individualized treatment effects with time-varying covariates and treatments.
New method models longitudinal data using variational inference and normalizing flows.
problem Handling high-dimensional longitudinal data with time dependency.
method Variational inference with normalizing flows for latent variables.
result The method achieves better likelihood estimates and more reliable missing data imputation.
Developed a flexible Bayesian g-formula for causal survival analysis with time-dependent confounding.
problem Estimating causal survival curves in longitudinal observational studies with time-varying treatments and confounding.
method Incorporated Bayesian Additive Regression Trees (BART) into the g-formula to model time-evolving generative components and mitigate bias due to model misspecification.
result Demonstrated improved empirical performance and practical utility of the proposed method through simulations and real-world data analysis.
Combining experimental and observational data for long-term causal effects.
problem Estimating causal effects of treatment on long-term outcomes using mixed data types.
method Three approaches for fusing experimental and observational data: equal confounding, shared confounder, and proxy variables.
result Developed estimators for each approach and analyzed their robustness.
Study finds non-adherence to schizophrenia meds leads to earlier adverse events.
problem Impact of medication non-adherence on adverse outcomes in schizophrenia patients.
method Survival analysis, causal inference methods (T-learner, S-learner, nearest neighbor matching), different amounts of longitudinal information.
result Non-adherence to schizophrenia meds advances adverse events by 1 to 4 months.
Framework predicts events from longitudinal and time-to-event data using MGCP and Cox model.
problem Predicting events from mixed longitudinal and time-to-event data.
method Uses multivariate Gaussian convolution process (MGCP) and Cox model for joint modeling. Implements variational inference to estimate parameters.
result Framework outperforms state-of-the-art approaches in synthetic and real-world data.
A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for longitudinal data, that is robust for finite samples based on recent advances in st…
Develops privacy-preserving methods for longitudinal linear regression.
problem Protecting individual information in longitudinal data with privacy-preserving statistics.
method Proposes a user-level private regression estimator and a privatized covariance estimator for longitudinal linear regression under user-level differential privacy.
result Establishes theoretical guarantees for practical user-level differential privacy estimation and inference in longitudinal linear regression.
Study integrates causal inference and temporal complexity measures to analyze mental health symptoms.
problem Examining how individual symptom trajectories reveal diagnostic patterns in mental disorders.
method Causal inference, graph analysis, temporal complexity measures, machine learning.
result 91% accuracy in diagnosing symptom dynamics, highlighting disorder-specific causal mechanisms.
Proposes a method for valid inference in GPLSIMs with longitudinal data.
problem Challenges in longitudinal data inference due to within-subject correlation and unstable variance estimation.
method Profile estimating-equation approach using spline approximation and block empirical likelihood.
result Block empirical likelihood ratio statistic with Wilks-type chi-square limit for joint inference.
HL-VAE extends VAE for heterogeneous temporal and longitudinal data.
problem Handling heterogeneous data in temporal and longitudinal datasets.
method Proposes HL-VAE, an extension of existing VAEs for temporal and longitudinal data, incorporating likelihood models for various data types.
result HL-VAE achieves competitive performance in missing value imputation and predictive accuracy.
Gradient boosting estimates Riesz representer for causal inference.
problem Estimating causal quantities using traditional methods is challenging and prone to variance issues.
method Gradient boosting algorithm to directly estimate Riesz representer.
result Gradient boosting performs similarly or better than traditional methods in estimating causal quantities.
The estimation of treatment effects is a pervasive problem in medicine. Existing methods for estimating treatment effects from longitudinal observational data assume that there are no hidden confounders, an assumption that is not testable in practice and, if it does not hold, leads to biased estimates. In this paper, w…
LPCI provides valid prediction intervals for longitudinal data.
problem Current conformal prediction methods for time series data lack cross-sectional coverage when applied to longitudinal datasets.
method Modeling residual data as a quantile fixed-effects regression problem, constructing prediction intervals with a trained quantile regressor.
result LPCI achieves valid cross-sectional coverage and outperforms existing benchmarks in terms of longitudinal coverage rates.
lgpr interprets longitudinal data to find covariate effects.
problem Inferring covariate effects from longitudinal data with complex structures and interactions.
method Additive Gaussian processes for nonparametric analysis.
result lgpr outperforms previous methods in identifying relevant covariates.
Targeted Learning uses robust statistics for reproducible research.
problem Improving reproducibility and rigor in statistical analyses.
method Principled standard for statistical estimation and inference, minimizing assumptions.
result Enhances reliability of statistical conclusions.
A new framework models multi-state events and biomarkers.
problem Limited representation of complex multi-state trajectories.
method General multi-state joint modeling framework.
result Accurate parameter recovery and personalized predictions.
New method estimates causal effects with multi-valued, time-varying treatments.
problem Estimating causal effects with complex time-varying exposures.
method Combines machine learning and semiparametric efficiency theory.
result Proposes an efficient, asymptotically normal estimator for marginal structural models.
A scalable model for high-dimensional longitudinal data.
problem Modeling high-dimensional, non-linear, time-varying longitudinal data.
method LMM-VAE, combining linear mixed models and amortized variational inference.
result Competitive performance across simulated and real-world datasets.
MMM model clusters mixed-type longitudinal data efficiently.
problem Challenges in clustering multivariate longitudinal mixed-type data.
method MMM model reorganizes data into a three-way structure, using a mixture of matrix-variate normal distributions.
result MMM model handles various data types (continuous, ordinal, binary, nominal, count) and temporal dependence.
Study improves Gaussian Process Latent Variable Model for noisy longitudinal data.
problem Noisy and incomplete longitudinal data makes learning representations difficult.
method Augment variational approximation with systematic samples of unseen observations.
result Demonstrates improved learning of Gaussian Process Dynamical Systems in noisy data.
Method constructs prediction intervals for time-varying individual treatment effects.
problem Accurately quantify uncertainty of individual treatment effects across multiple decision points.
method Conformal inference techniques for time-varying ITEs with weaker assumptions.
result Guaranteed lower bound for coverage dependent on data non-exchangeability.
Automates kernel discovery for longitudinal data analysis.
problem Handling irregularly sampled, sparse longitudinal data with multilevel correlation.
method Combines deep neural networks and non-parametric kernel methods to discover complex multilevel correlation structure.
result Significantly outperforms state-of-the-art methods on benchmark data sets.
TransformerLSR models longitudinal, recurrent, and survival data jointly.
problem Joint modeling of longitudinal measurements, recurrent events, and survival data with dependencies.
method Transformer-based deep learning framework integrating deep temporal point processes and latent structure representation.
result TransformerLSR effectively models all three components simultaneously, demonstrating necessity and effectiveness through simulations and real-world data.
Framework for joint learning of tasks on dementia data with missing values.
problem Lack of multi-task learning, handling time-dependent data, and missing values in dementia forecasting.
method Proposes SSHIBA model using Bayesian variational inference for imputation and combined information from different views.
result SSHIBA model outperforms baselines in predicting diagnosis, ventricle volume, and clinical scores in dementia.
In statistical learning, high covariate dimensionality poses challenges for robust prediction and inference. To address this challenge, supervised dimension reduction is often performed, where dependence on the outcome is maximized for a selected covariate subspace with smaller dimensionality. Prevalent dimension reduc…
Proposes Deep LTMLE for estimating dynamic treatment effects in longitudinal studies.
problem Estimating counterfactual mean outcomes under dynamic treatment policies in longitudinal settings.
method Uses a transformer architecture with temporal-difference learning for initial estimation, followed by TMLE correction and statistical inference.
result Demonstrates superior performance in complex, long-term scenarios compared to existing methods.
New method prevents invalid inference after causal discovery.
problem Invalid inference after causal discovery.
method Developed tools for valid post-causal-discovery inference.
result Our method provides reliable coverage while achieving more accurate causal discovery.
Probabilistic models can handle causal inference without special tools.
problem Confusion over necessary tools for causal inference.
method Demonstrated through concrete examples that causal questions can be answered using standard probabilistic models.
result Causal questions can be addressed using standard probabilistic modelling and inference.
Adversarial deep learning improves EEG-based person identification.
problem Exploiting temporally correlated structures and session variability in EEG data.
method Adversarial inference approach to learn session-invariant representations.
result Improvements in person identification robustness from longitudinal EEG data.
LLmFPCA-detect detects anomalies in sparse longitudinal text data using LLMs and mFPCA.
problem Challenges in detecting patterns and anomalies in sparse longitudinal textual data.
method Pairs LLM-based text embeddings with mFPCA to detect clusters and anomalies.
result LLmFPCA-detect outperforms state-of-the-art baselines on Amazon and Wikipedia datasets.
We link disjoint longitudinal data for rare disease patients using latent representations and mixed-effects regression.
problem Analyzing treatment switches in rare diseases with limited data and changing measurement instruments.
method We embed item values into a shared latent space using variational autoencoders and apply mixed-effects regression to quantify treatment effects.
result Our approach allows for statistical inference and quantifies the impact of treatment switches in spinal muscular atrophy.
Deep learning aids causal inference in complex settings.
problem Estimating heterogeneous treatment effects in non-linear, time-varying, and encoded confounders.
method Intuitive introduction to deep learning and causal inference, focusing on observational data.
result Maximizes accessibility to causal inference through deep learning.
Book introduces ML and AI for causal inference.
problem Uncertainty in causal relationships.
method Structural equation models, DAGs, SCMs, and Double/Debiased Machine Learning.
result Improved inference in causal models using predictive tools.