LMM predicts healthcare costs and risks with improved accuracy.
problem Wasteful healthcare spending and inefficiencies in risk prediction.
method Generative pre-trained transformer trained on patient event sequences.
result Improves cost prediction by 14.1% and chronic conditions prediction by 1.9%.
A statistical description and model of individual healthcare expenditures in the US has been developed for measuring value in healthcare. We find evidence that healthcare expenditures are quantifiable as an infusion-diffusion process, which can be thought of intuitively as a steady change in the intensity of treatment …
Study predicts high-cost patients using insurance claims data.
problem Accurately identifying high-cost patients to manage costs.
method Applied machine learning to health insurance claims data.
result Developed a high-performance algorithm with 91.2% AUC.
Super learner with Huber loss improves cost prediction and causal effect estimation in healthcare expenditure data.
problem Challenges in modeling healthcare expenditure distributions with standard super learning methods.
method Proposes a super learner using Huber loss, a robust loss function that down-weights outliers.
result Demonstrates appreciable finite-sample gains in cost prediction and causal effect estimation.
Two large medical dialogue datasets for improving healthcare.
problem Improving healthcare through better dialogue systems.
method Building two large-scale medical dialogue datasets: MedDialog-EN and MedDialog-CN.
result The datasets are the largest medical dialogue datasets to date.
Predictive models are finding an increasing number of applications in many industries. As a result, a practical means for trading-off the cost of deploying a model versus its effectiveness is needed. Our work is motivated by risk prediction problems in healthcare. Cost-structures in domains such as healthcare are quite…
Simulation framework assesses ROI of chronic disease adherence and policy timing.
problem Uncertainty in ROI of adherence-enhancing interventions under heterogeneous patient behavior and socioeconomic variation.
method Simulation-based framework integrating disease progression, time-varying adherence, and policy timing.
result Early and adaptive interventions yield highest ROI, exceeding 20% under certain conditions.
AM-PPI uses multiple predictors to reduce label cost in healthcare AI.
problem Reduces label cost in post-deployment monitoring of healthcare AI.
method Combines model predictions with a small labeled sample, routing each instance to a cost-appropriate subset of predictors.
result Produces narrower confidence intervals than single-predictor methods.
Deep neural network predicts health costs better than traditional models.
problem Accurate prediction of healthcare costs for optimal cost management.
method Developed a deep neural network to predict future health care costs from health insurance claims records.
result Deep neural network outperformed ridge regression and Morbi-RSA models in cost prediction.
One of the main issues affecting the Italian NHS is the healthcare deficit: according to current agreements between the Italian State and its Regions, public funding of regional NHS is now limited to the amount of regional deficit and is subject to previous assessment of strict adherence to constraint on regional healt…
In the modern healthcare system, rapidly expanding costs/complexity, the growing myriad of treatment options, and exploding information streams that often do not effectively reach the front lines hinder the ability to choose optimal treatment decisions over time. The goal in this paper is to develop a general purpose (…
High quality risk adjustment in health insurance markets weakens insurer incentives to engage in inefficient behavior to attract lower-cost enrollees. We propose a novel methodology based on Markov Chain Monte Carlo methods to improve risk adjustment by clustering diagnostic codes into risk groups optimal for health ex…
The paper develops a method to optimize individualized treatment rules for cost-effectiveness.
problem Developing cost-effective individualized treatment rules for healthcare policy.
method Using conditional random forest and net-monetary-benefit (NMB) to estimate optimal CE-ITR.
result The approach optimizes healthcare resource allocation by maximizing health gains and minimizing costs.
Study fair healthcare predictions without harming patients.
problem Balancing fairness and avoiding unnecessary harm in healthcare predictions.
method Formalizes Pareto-optimal approach to minimize risk disparity without causing harm, dynamically re-balancing subgroup risks.
result Demonstrates a method to train neural networks achieving fair predictions without unnecessary harm.
Reducing ICD-10 code granularity improves cost model accuracy and stability.
problem High-dimensional regression with ICD-10 codes leads to unstable coefficient estimates.
method Log-linear analytics approach to cost model regularization through diagnostic code merging.
result Reducing ICD-10 code granularity from 7 characters to 6 or fewer improves model interpretability and consistency.
Framework for AI healthcare products from concept to market.
problem Failure of AI products to reach clinics despite promising potential.
method Decision-making framework for AI healthcare product development.
result Guides through a three-phase process to market launch of validated AI products.
System automates identification of cancer drug repurposing from PubMed.
problem Manual extraction of cancer drug repurposing evidence from scientific publications is infeasible.
method NLP pipeline including querying, filtering, entity extraction, classification, and study type classification.
result Automated system extracts cancer drug repurposing evidence from PubMed abstracts.
Control charts have traditionally been used in industrial statistics, but are constantly seeing new areas of application, especially in the age of Industry 4.0. This paper introduces a new method, which is suitable for applications in the healthcare sector, especially for monitoring a health-characteristic of a patient…
AFA evaluates AI feature acquisition strategies in domains with high costs.
problem Evaluate AI feature acquisition strategies in domains with high costs.
method Apply missing data methods and offline reinforcement learning under NDE and NUC assumptions.
result Propose a novel semi-offline reinforcement learning framework with three new estimators.
Framework identifies comorbidities for frequent ED and inpatient visits.
problem Reducing resource usage and costs in frequent patients.
method Developed MSAR algorithm to identify comorbidities.
result MSAR identifies conditions most associated with reoccurring ED and inpatient visits.
Study assesses CNN model robustness to noise in low-cost CT scans.
problem Evaluate CNN model performance on noisy, artifact-prone low-cost CT images.
method Developed and tested a CNN model for head CT triage, varying tube current and projections.
result Model remains robust to reduced tube current and fewer projections, maintaining AUROC close to original.
This study proposes a method to predict ICU infections from imbalanced data using clustering-based undersampling and ensemble classifiers.
problem Predicting healthcare-associated infections in ICU patients from imbalanced data.
method Clustering-based undersampling strategy combined with ensemble classifiers.
result The proposed method outperforms other resampling techniques in predicting ICU infections.
ICP improves prediction intervals for continuous outcomes at lower computational cost.
problem Systematic bias in point predictions that undermines their use in decision-making.
method Develops Isotonic Conformal Prediction (ICP) framework to decouple calibration from prediction-set construction.
result SICP and TICP procedures match SC-CP coverage at lower computational cost.
Optimizes risk assessment tools using mixed-integer programming.
problem Challenges in healthcare risk assessment due to label scarcity and asymmetric misclassification costs.
method Jointly optimizes scoring weights and category thresholds via mixed-integer programming (MIP).
result Prevents label-scarce category collapse and achieves more accurate risk categorization.
Approves updates to machine learning models in healthcare based on accumulating data.
problem Designing policies to autonomously approve updates to machine learning algorithms in non-stationary settings.
method Learning-to-approve (L2A) approach that uses accumulating monitoring data to learn how to approve modifications.
result L2A learns to abstain when performance drops are common and approves beneficial modifications quickly when the distribution is stable.
Federated Cox model handles non-proportional hazards in siloed data.
problem Handling non-proportional hazards in federated healthcare data.
method Developed a federated Cox model that relaxes proportional hazards assumption.
result Federated model performs similarly to standard models on clinical datasets.
Traditionally, machine learning algorithms rely on the assumption that all features of a given dataset are available for free. However, there are many concerns such as monetary data collection costs, patient discomfort in medical procedures, and privacy impacts of data collection that require careful consideration in a…
It is not clear how to target patients who are most likely to benefit from digital care management programs ex-ante, a shortcoming of current risk score based approaches. This study focuses on defining impactability by identifying those patients most likely to benefit from technology enabled care management, delivered …
Study proposes BFEL framework for privacy-preserving FL in personalized healthcare.
problem Privacy and security concerns in traditional cloud-centric ML, especially in wearable devices.
method Develops a blockchain-enhanced federated edge learning (BFEL) framework based on FedCurv, incorporating fisher information matrix and public key encryption.
result Significant reduction in communication cost and high efficiency for federated training on non-iid and heterogeneous data.
FavMac maximizes value while controlling cost in multi-label prediction.
problem Value-maximizing predictions with strict cost control in multi-label scenarios.
method FavMac pipeline combining any multi-label classifier with online update mechanism.
result FavMac achieves higher value with strict cost control compared to baselines.
Large-scale computational experiments, often running over weeks and over large datasets, are used extensively in fields such as epidemiology, meteorology, computational biology, and healthcare to understand phenomena, and design high-stakes policies affecting everyday health and economy. For instance, the OpenMalaria f…
We propose using canonical correlation analysis (CCA) to generate features from sequences of medical billing codes. Applying this novel use of CCA to a database of medical billing codes for patients with diverticulitis, we first demonstrate that the CCA embeddings capture meaningful relationships among the codes. We th…
Predicting drug-target interactions (DTI) is an essential part of the drug discovery process, which is an expensive process in terms of time and cost. Therefore, reducing DTI cost could lead to reduced healthcare costs for a patient. In addition, a precisely learned molecule representation in a DTI model could contribu…
Probabilistic ML improves healthcare data analysis.
problem Insufficient understanding and incomplete data in healthcare.
method Examination of probabilistic machine learning models for healthcare challenges.
result Probabilistic models enhance healthcare data analysis and model building.
System recommends workouts and predicts success rates using RNNs.
problem Promoting healthy lifestyles through personalized exercise recommendations.
method Two interconnected recurrent neural networks (RNNs) using historical workout data.
result Interconnected-RNN model predicts exercise success rates with improved accuracy.
This work is motivated by the needs of predictive analytics on healthcare data as represented by Electronic Medical Records. Such data is invariably problematic: noisy, with missing entries, with imbalance in classes of interests, leading to serious bias in predictive modeling. Since standard data mining methods often …
Meta-learning interpretable decision trees with synthetic data.
problem Lack of efficient, scalable methods for generating synthetic data for decision tree meta-learning.
method Synthetic generation of near-optimal decision trees using the MetaTree transformer architecture.
result Meta-learning of decision trees achieves performance comparable to real-world data or optimal decision trees, with significant computational cost reduction.
Big data analytics improves healthcare through early detection and quality life.
problem Limited access to healthcare data hinders evidence-based decision-making.
method Analysis of healthcare data using various tools and techniques.
result Big data analytics enhances healthcare quality and patient outcomes.
Model predicts wound and episode-level readmission risk and time to re-admit.
problem Identify patients at high risk of re-admission to prevent wound recurrences and reduce healthcare costs.
method Data-driven analysis of wound care and episode-level patient data.
result Model achieves high recall and precision for predicting re-admission risk and time.
Quantized BNNs maintain uncertainty estimation quality despite reduced precision.
problem Reduced precision in BNNs due to quantization.
method Quantized BNNs with 32-bit weights and activations compressed to 16-bit integers.
result Uniform quantization does not significantly degrade uncertainty estimation quality.
Batteryless or so called passive wearables are providing new and innovative methods for human activity recognition (HAR), especially in healthcare applications for older people. Passive sensors are low cost, lightweight, unobtrusive and desirably disposable; attractive attributes for healthcare applications in hospital…
Survey on securing ML for healthcare, addressing privacy and robustness issues.
problem Security and robustness challenges in healthcare ML/DL applications.
method Overview of security and privacy methods for ML in healthcare.
result Discussion of current research challenges and future directions.
This paper solves the problem of optimal dynamic consumption, investment, and healthcare spending with isoelastic utility, when natural mortality grows exponentially to reflect Gompertz' law and investment opportunities are constant. Healthcare slows the natural growth of mortality, indirectly increasing utility from c…
IAL uses interactive learning to improve model performance with minimal human feedback.
problem Overfitting and high human interaction cost in training neural networks.
method IAL framework with NAP attention generator and reranking algorithm.
result IAL significantly outperforms baselines with less retraining and human interaction.
Study optimal healthcare spending under Epstein-Zin preferences for longevity.
problem Optimizing healthcare spending to extend longevity under Epstein-Zin preferences.
method Formulated Epstein-Zin utilities over a controllable random horizon using backward stochastic differential equations and HJB equations.
result Calibrated model accurately reflects actual mortality data and compares healthcare efficacy between countries.
Machine learning classifies Parkinson's Disease stages from walker sensors data.
problem Limited cost-effective methods for quantitatively assessing Parkinson's Disease stages.
method Machine learning applied to walker-mounted sensors data, feature selection methods compared.
result Feature selection method using ANOVA provides similar accuracy to full feature set and is clinically interpretable.
Study improves conformal prediction for EEG classification in healthcare, enhancing coverage.
problem Uncertainty quantification in clinical predictions, especially in distribution-shifted settings.
method Personalized calibration strategies to improve coverage of prediction sets.
result Coverage improved by over 20 percentage points with comparable prediction set sizes.
A recommendation framework helps users choose healthcare interventions.
problem Choice overload in online healthcare communities.
method Multi-Armed Bandit (MAB) approach with innovative model components.
result Our recommendation design outperforms state-of-the-art systems.