The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in the epidemic. Individuals who are prescribed opioids, and who are diagnosed wit…
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23 results for “health-state”
Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and irregular in time. We introduce DeepCare, an end-to-end deep dynamic neural network t…
A Longitudinal Attribute-Conditioned Neural Network (LANTERN) framework for modeling health-state transition probabilities in irregular longitudinal data.
problem Estimating long-term care transition probabilities in irregular longitudinal health data.
method A neural network that learns from individual health history, incorporates time elapsed, and conditions on demographic and socioeconomic attributes.
result Improves severe disability discrimination and maintains strong calibration.
The huge wealth of data in the health domain can be exploited to create models that predict development of health states over time. Temporal learning algorithms are well suited to learn relationships between health states and make predictions about their future developments. However, these algorithms: (1) either focus …
The paper analyzes optimal timing for converting wealth into annuities in the presence of a mortality shock.
problem Optimal timing for converting retirement wealth into annuities under a mortality risk.
method Derives explicit closed-form solutions for value function and optimal stopping boundaries.
result The optimal strategy depends on the interplay between annuity attractiveness, investment returns, and bequest motives.
The paper develops a valuation framework for GLWB-LTC contracts with Levy dynamics and stochastic interest rates.
problem Valuation of GLWB-LTC contracts with financial guarantees, longevity protection, and health-contingent LTC payments.
method Coupling a recombining Hull-White trinomial tree with an IMEX finite difference scheme, incorporating a seven-state health model.
result Hybrid tree-IMEX method delivers stable long-maturity prices consistent with simulation benchmarks.
Improving decision-making via risk-based active learning: Probabilistic discriminative classifierscs.LG
Discriminative classifiers improve decision-making in SHM systems.
problem Lack of descriptive labels for SHM data.
method Risk-based active learning with discriminative classifiers.
result Discriminative classifiers offer improved robustness and reduced inspection costs.
Risk-based active learning improves SHM decision-making.
problem Lack of prior labels for structural health monitoring.
method Risk-based active learning approach to guide data labeling.
result Improves decision-maker's performance in SHM.
The Thermodynamic Approach to Whole-Life Insurance: A Method for Evaluation of Surrender Riskq-fin.GN
Model evaluates insurance risk using thermodynamic principles.
problem Risk of lapses due to adverse selection in insurance.
method Collective model with diffusion process influenced by statistical mechanics.
result Derives level premium to evaluate insurance risk.
The field of mobile health aims to leverage recent advances in wearable on-body sensing technology and smart phone computing capabilities to develop systems that can monitor health states and deliver just-in-time adaptive interventions. However, existing work has largely focused on analyzing collected data in the off-l…
Predicting unscheduled breakdowns of plasma etching equipment can reduce maintenance costs and production losses in the semiconductor industry. However, plasma etching is a complex procedure and it is hard to capture all relevant equipment properties and behaviors in a single physical model. Machine learning offers an …
Blood lactate concentration is a strong indicator of mortality risk in critically ill patients. While frequent lactate measurements are necessary to assess patient's health state, the measurement is an invasive procedure that can increase risk of hospital-acquired infections. For this reason we formally define the prob…
The health state assessment and remaining useful life (RUL) estimation play very important roles in prognostics and health management (PHM), owing to their abilities to reduce the maintenance and improve the safety of machines or equipment. However, they generally suffer from this problem of lacking prior knowledge to …
For a learning task, data can usually be collected from different sources or be represented from multiple views. For example, laboratory results from different medical examinations are available for disease diagnosis, and each of them can only reflect the health state of a person from a particular aspect/view. Therefor…
Deep learning improves oilfield equipment maintenance and reduces downtime.
problem Predicting equipment failure in oilrigs to minimize downtime.
method Developed and tested neural networks on oilfield datasets, using data processing and feature extraction.
result Deep learning can predict oilfield equipment failure with reduced downtime.
HMRNN combines HMMs and neural networks for Alzheimer's disease forecasting.
problem Improving disease progression modeling with hidden states not fully known.
method Developed HMRNN combining HMMs and recurrent neural networks.
result HMRNN improves disease forecasting and offers novel clinical interpretation.
Framework combines HMM and MTGCN for spatiotemporal causal inference in clinical data.
problem Challenges in observing direct treatment effects in clinical domains.
method Integrates Hidden Markov Model and Multi Task and Multi Graph Convolutional Network for spatiotemporal data.
result Advances predictive causal inference by structurally adapting to spatiotemporal complexities.
Clinical researchers use disease progression models to understand patient status and characterize progression patterns from longitudinal health records. One approach for disease progression modeling is to describe patient status using a small number of states that represent distinctive distributions over a set of obser…
Prognostics or early detection of incipient faults is an important industrial challenge for condition-based and preventive maintenance. Physics-based approaches to modeling fault progression are infeasible due to multiple interacting components, uncontrolled environmental factors and observability constraints. Moreover…
The paper addresses sampling bias in risk-based active learning.
problem Sampling bias in active learning leads to poor decision-making performance.
method The paper uses a semi-supervised Gaussian mixture model with an EM algorithm to counteract sampling bias.
result The EM algorithm effectively incorporates pseudo-labels for unlabelled data, reducing sampling bias.
Paper presents a data preprocessing method for PHM models.
problem Lack of consistent data preprocessing for PHM applications.
method Comprehensive pipeline for sensor data preprocessing.
result Creation of clean data sets for training machinery health state classifiers.
Depression and anxiety are critical public health issues affecting millions of people around the world. To identify individuals who are vulnerable to depression and anxiety, predictive models have been built that typically utilize data from one source. Unlike these traditional models, in this study, we leverage a rich …
Condition monitoring is one of the routine tasks in all major process industries. The mechanical parts such as a motor, gear, bearings are the major components of a process industry and any fault in them may cause a total shutdown of the whole process, which may result in serious losses. Therefore, it is very crucial t…