Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an interpretable and generalizable model for early mortality prediction in elderly patients wi…
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48 results for “elderly patients”
GRU-D detects age-specific missing patterns in vital signs.
problem Temporal missingness in clinical time series data.
method Gated recurrent unit with decay mechanisms (GRU-D) trained on MIMIC-IV vital signs.
result GRU-D achieves AUROC 0.780 and AUPRC 0.810 on bootstrapped data.
Risk prediction is central to both clinical medicine and public health. While many machine learning models have been developed to predict mortality, they are rarely applied in the clinical literature, where classification tasks typically rely on logistic regression. One reason for this is that existing machine learning…
We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This approach uses spherical harmonics (SPHARM) coefficients to model the shape of the hi…
New method estimates optimal dose intervals for personalized treatment.
problem Learning optimal dose intervals from observational data.
method Probability dose interval (PDI) method using DC algorithm.
result Consistent policy with risk converging to best-in-class at root-n rate.
ESE-FN improves elderly activity recognition accuracy.
problem Recognizing individual actions and human-object interactions in elderly activities.
method Exploits multi-modal features from RGB videos and skeleton sequences using ESE attentions and a new Multi-modal Loss.
result ESE-FN achieves best accuracy on ETRI-Activity3D dataset.
Paper uses TDA for automated Parkinson's disease classification and severity assessment.
problem Manual diagnosis of neurological diseases is time-consuming and inaccurate.
method Combines Topological Data Analysis (TDA) with machine learning on postural shift data.
result Proposes a stable and accurate method for classifying Parkinson's disease.
Do Pension Benefits Accelerate Cognitive Decline in Late Adulthood? Evidence from Rural Chinaecon.GN
Pension benefits in rural China lead to cognitive decline among the elderly.
problem Cognitive decline in late adulthood among rural Chinese elderly.
method Examined the effects of a new pension scheme on cognitive performance.
result Pension benefits negatively impact cognitive functioning, particularly delayed recall.
Falling is a commonly occurring mishap with elderly people, which may cause serious injuries. Thus, rapid fall detection is very important in order to mitigate the severe effects of fall among the elderly people. Many fall monitoring systems based on the accelerometer have been proposed for the fall detection. However,…
1-D Convlutional Neural Networks for the Analysis of Pupil Size Variations in Scotopic Conditionseess.IV
It is well known that a systematic analysis of the pupil size variations, recorded by means of an eye-tracker, is a rich source of information about a subject's arousal and cognitive state. Current methods for pupil analysis are limited to descriptive statistics, struggle in handling the wide inter-subjects variability…
Predicts clinical events using a landmark approach with machine learning for large biomarker histories.
problem Dynamic prediction of clinical events from large biomarker histories.
method Landmark approach extended to endogenous markers history combined with machine learning methods for survival data.
result Superlearner combining regularized regressions and random survival forests outperforms standard survival models.
New AI model optimizes personalized care for elderly residents.
problem Limited care workforce impacts health outcomes and quality of life.
method Bandit algorithms for personalized care planning.
result Improves care quality and health outcomes through personalized care planning.
Recent research has demonstrated the brittleness of machine learning systems to adversarial perturbations. However, the studies have been mostly limited to perturbations on images and more generally, classification that does not deal with temporally varying inputs. In this paper we ask "Are adversarial perturbations po…
We present a practical health-theme machine learning (ML) application concerning `AI for social good' domain for `Producing Good Outcomes' track. In particular, the solution is concerning the problem of a potential elderly adult dementia onset prediction in aging societies. The paper discusses our attempt and encouragi…
Continuous monitoring of cardiac health under free living condition is crucial to provide effective care for patients undergoing post operative recovery and individuals with high cardiac risk like the elderly. Capacitive Electrocardiogram (cECG) is one such technology which allows comfortable and long term monitoring t…
DynForest predicts event probabilities from longitudinal data, handling endogenous predictors.
problem Predicting individual risk using longitudinal patient history.
method Random survival forests with time-fixed features from longitudinal predictors.
result DynForest provides accurate individual event probability predictions.
Improved forecasting of suicide attempts using LSGPs for patients with little data.
problem Challenges in predicting suicide attempts due to their rarity and patient heterogeneity.
method Introduced Latent Similarity Gaussian Processes (LSGPs) to capture patient heterogeneity.
result LSGPs outperform baseline models, even without kernel-design, and offer new insights into patient similarity.
Efficiently fine-tunes patient-independent seizure detection models with tensor kernel machine.
problem Improving seizure detection accuracy for wearable devices.
method Transfer learning with tensor kernel machine using canonical polyadic decomposition.
result Patient fine-tuned model achieves high performance with smaller model size.
Personalized models explain TB treatment outcomes considering patient context.
problem Heterogeneity in TB treatment outcomes due to co-morbidities.
method Multi-task learning approach encoding patient context into personalized models.
result Identifies anemia, age of onset, and HIV as influential for treatment efficacy.
Simulates patient pathways to detect delayed rare disease diagnoses.
problem Delayed rare disease diagnoses in France, causing health system and patient harm.
method Probabilistic modelling of patient pathways to create an alert system.
result Alert system detects and refers wandering patients to CRMRs.
Model predicts wound and episode-level readmission risk and time to re-admit.
problem Identify patients at high risk of re-admission to prevent wound recurrences and reduce healthcare costs.
method Data-driven analysis of wound care and episode-level patient data.
result Model achieves high recall and precision for predicting re-admission risk and time.
Currently, approximately 30% of epileptic patients treated with antiepileptic drugs (AEDs) remain resistant to treatment (known as refractory patients). This project seeks to understand the underlying similarities in refractory patients vs. other epileptic patients, identify features contributing to drug resistance acr…
Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute coronary syndrome (ACS) is a syndrome due to sudden decrease of coronary artery blood f…
The health outcomes of high-need patients can be substantially influenced by the degree of patient engagement in their own care. The role of care managers includes that of enrolling patients into care programs and keeping them sufficiently engaged in the program, so that patients can attain various goals. The attainmen…
Deep Representation Learning of Electronic Health Records to Unlock Patient Stratification at Scaleq-bio.QM
Deep learning model creates patient representations for scalable EHR-based stratification.
problem Challenges in summarizing and representing patient data from EHRs prevent scalable stratification analysis.
method Unsupervised framework based on deep learning (ConvAE) using word embeddings, CNNs, and autoencoders.
result ConvAE significantly outperformed baselines in clustering diverse patient cohorts, identifying clinically relevant subtypes.
Characterizing a patient's progression through stages of sepsis is critical for enabling risk stratification and adaptive, personalized treatment. However, commonly used sepsis diagnostic criteria fail to account for significant underlying heterogeneity, both between patients as well as over time in a single patient. W…
Personalized Risk Scoring for Critical Care Patients using Mixtures of Gaussian Process Expertscs.LG
We develop a personalized real time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs. Heterogeneity of the patients population is captured via a hierarchical latent class model. The proposed algorithm aims t…
Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress through disease stages at varying rates. This leads to pathophysiological misalig…
Study automates detection of visitation disruptions in ICU patients.
problem Difficulty in detecting frequent visitation disruptions in ICU patients.
method Used DensePose R-CNN model to count people in video frames, analyzed disruptions and patient outcomes.
result Automated method detects visitation disruptions, impacts on pain and length of stay examined.
This paper proposes a real-time embedded fall detection system using a DVS(Dynamic Vision Sensor) that has never been used for traditional fall detection, a dataset for fall detection using that, and a DVS-TN(DVS-Temporal Network). The first contribution is building a DVS Falls Dataset, which made our network to recogn…
Bayesian methods improve group testing for identifying infected patients.
problem Identifying infected patients from group testing results with false positives.
method Bayesian inference and belief propagation algorithm, combined with expectation-maximization method.
result True-positive rate improved by considering credible intervals.
To address potential gaps noted in patient monitoring in the hospital, a novel patient behavior detection system using mmWave radar and deep convolution neural network (CNN), which supports the simultaneous recognition of multiple patients' behaviors in real-time, is proposed. In this study, we use an mmWave radar to t…
Model identifies key problems in HIV patients' records.
problem Complex and time-consuming task of identifying patient problems from electronic health records.
method Unsupervised phenotyping approach that jointly learns phenotypes from structured and unstructured data.
result Learned phenotypes and their relatedness are clinically valid and surpass existing methods.
Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative effectiveness research. One major carrier for conducting patient similarity resea…
Study develops electronic phenotypes of ICU patient acuity.
problem Limited time for patient acuity assessments and imprecise clinical trajectory prediction.
method Developed electronic phenotypes using automated variable retrieval in electronic health records.
result Identified three phenotypes: persistently stable, persistently unstable, and transitioning from unstable to stable.
Deep learning clusters patient time-series data for better prognosis.
problem Clustering time-series data for patient phenotyping and prognosis.
method Deep predictive clustering with novel loss functions for future outcome distribution.
result Model achieves superior clustering performance and identifies meaningful patient subgroups.
Multi-output Gaussian processes (GPs) are a flexible Bayesian nonparametric framework that has proven useful in jointly modeling the physiological states of patients in medical time series data. However, capturing the short-term effects of drugs and therapeutic interventions on patient physiological state remains chall…
Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have increased since the millennium change. MIMIC-III, a freely accessible critical care data…
Machine learning detects NASH patients from medical claims data.
problem Detecting undiagnosed NASH patients for screening and management.
method Gradient-boosted decision trees trained on administrative medical claims data.
result Model precision for NASH detection is significantly higher than NASH incidence.
Many computational models were proposed to extract temporal patterns from clinical time series for each patient and among patient group for predictive healthcare. However, the common relations among patients (e.g., share the same doctor) were rarely considered. In this paper, we represent patients and clinicians relati…
The paper tracks patient recovery using graphs of joint movement data.
problem Tracking individual patient recovery trajectories in physical therapy.
method Bayesian learning of Random Geometric Graphs from joint movement data.
result Optimal exercise routines can be recommended based on patient recovery data.
Enhances understanding of patient healthcare journeys using self-attention.
problem Capturing hidden dependencies in multi-level patient journey data.
method Proposes a multi-level self-attention network (MusaNet) for encoding patient journeys.
result MusaNet produces higher-quality representations than state-of-the-art methods.
Paper proposes a new method for more accurate group testing of infected patients.
problem Identifying infected patients efficiently with reduced tests and corrected errors.
method Adaptive design of pools based on Bayesian posterior prediction using belief propagation algorithm.
result The proposed method results in more accurate identification of infected patients.
New model identifies patient-specific disease root causes.
problem Identifying root causes of complex diseases varying between patients.
method Generalized Root Causal Inference (GRCI) algorithm for heteroscedastic noise model.
result GRCI accurately extracts patient-specific root causes.
Rare diseases affecting 350 million individuals are commonly associated with delay in diagnosis or misdiagnosis. To improve those patients' outcome, rare disease detection is an important task for identifying patients with rare conditions based on longitudinal medical claims. In this paper, we present a deep learning m…
In Vitro Fertilization (IVF) Cumulative Pregnancy Rate Prediction from Basic Patient Characteristicsq-bio.QM
Tens of millions of women suffer from infertility worldwide each year. In vitro fertilization (IVF) is the best choice for many such patients. However, IVF is expensive, time-consuming, and both physically and emotionally demanding. The first question that a patient usually asks before the IVF is how likely she will co…
Deep learning model predicts severe COVID-19 outcomes.
problem Predicting severe COVID-19 outcomes in ED patients.
method Deep feature fusion model using EHR data and CXR images.
result CO-RISK score achieved AUC of 0.95 and 0.92 for 24 and 72 hours predictions, superior to human performance.
Adaptive prediction timing improves healthcare outcomes by predicting patient events at the right frequency.
problem Inconsistent prediction granularity in healthcare models.
method Introduces a novel approach using Bayesian recurrent models and a new aggregation method to adapt prediction frequency based on uncertainty.
result Adaptive prediction timing leads to improved predictive performance, especially in the critical first 12 hours of patient stay.