Study evaluates federated learning for ICU survival prediction using eICU data.
problem Training models on multi-center healthcare data without data sharing.
method Federated Averaging, varying hyper-parameters, analyzing client sizes.
result Optimal performance with a large number of local training epochs and reduced communication costs.
Public benchmark for machine learning models in critical care.
problem Lack of public benchmarks for machine learning in critical care.
method Defined four tasks (mortality prediction, length of stay, phenotyping, decompensation risk) and compared clinical and deep learning models on eICU dataset.
result First public benchmark on multi-centre critical care dataset, comparing clinical models with predictive models.
Evaluating prediction models under covariate shift and selective labels
problem Model performance evaluation under distribution shift and selection bias
method Double machine learning
result Accurate estimation of target risk
Study develops an interpretable model for early mortality prediction in elderly MODS patients.
problem High mortality risk in elderly patients with MODS, unsatisfactory current scoring systems.
method Used eXtreme Gradient Boosting with SHapley Additive exPlanations on MIMIC-III, eICU-CRD, and PLAGH-S datasets.
result Interpretable model outperforms baseline models and clinical scores in predicting hospital mortality.
New model predicts ICU patient stays more accurately.
problem Efficient ICU bed allocation under resource constraints.
method Temporal Pointwise Convolutional Networks (TPC) combining temporal and pointwise convolutions.
result Significant performance improvements over LSTM and Transformer models.
A large volume of research has considered the creation of predictive models for clinical data; however, much existing literature reports results using only a single source of data. In this work, we evaluate the performance of models trained on the publicly-available eICU Collaborative Research Database. We show that cr…
This study improves AKI prediction precision using CNN on EHR data.
problem Improving early prediction of AKI in ICU patients.
method Convolutional Neural Network (CNN) on EHR data.
result Best AUROC up to 0.988 on MIMIC-III and 0.936 on eICU data sets.
Deep learning with medical data often requires larger samples sizes than are available at single providers. While data sharing among institutions is desirable to train more accurate and sophisticated models, it can lead to severe privacy concerns due the sensitive nature of the data. This problem has motivated a number…
AdaptHetero uses MLI to tailor EHR models for subgroup-specific predictions.
problem Lack of subgroup-specific, operationalizable modeling strategies in EHRs.
method Integrates MLI with unsupervised clustering to identify subgroup-specific characteristics.
result Improves predictive performance by up to 174.39 percent across many subpopulations.
Proposes DeepSDRF for continuous treatment recommendation from clinical survival data.
problem Continuous treatment recommendation in medical settings with survival data.
method Deep Survival Dose Response Function (DeepSDRF) for learning conditional average dose response (CADR) function.
result Similar performance of recommender algorithms based on random search and reinforcement learning.
Predicting blood lactate levels helps manage ICU patients without invasive tests.
problem Predict blood lactate levels accurately in ICU patients without invasive tests.
method Defined a benchmark problem, evaluated different prediction algorithms, and investigated missing value imputation methods.
result Promising prediction results show the potential of machine learning in ICU care.
Novel metrics improve machine learning models for ICU patient care.
problem Predicting vital sign trajectories for early detection of adverse events.
method Developed novel performance metrics aligned with clinical contexts, validated on simulated and real datasets, and optimized neural networks using these metrics.
result Neural networks trained with these metrics excel in predicting clinically significant events.
Study predicts antimicrobial resistance in ICU patients quickly.
problem Delayed AMR testing in ICU leads to suboptimal treatment.
method Developed predictive models using clinical and microbiological data.
result Machine learning models predict AMR with higher accuracy than naive model.
Study compares federated and centralized learning for patient data privacy.
problem Ensuring privacy in machine learning models trained on electronic health records.
method Examined private and non-private federated learning for clinical prediction tasks.
result Differentially private stochastic gradient descent is effective in centralized learning but challenging in federated learning.
Paper proposes robust method to detect risk heterogeneity across ethnic groups.
problem Detecting risk heterogeneity across ethnic groups in ICU studies.
method Proposes a robust framework using Neyman orthogonality for inference.
result Demonstrates improved inferential stability and reduced bias compared to standard methods.
New model predicts ICU patients' stay duration efficiently.
problem Efficient ICU bed allocation under resource constraints.
method Temporal Pointwise Convolution (TPC) model combining temporal and pointwise convolutions.
result Significant performance improvements over LSTM and Transformer models.
In critical care, intensivists are required to continuously monitor high dimensional vital signs and lab measurements to detect and diagnose acute patient conditions. This has always been a challenging task. In this study, we propose a novel self-correcting deep learning prediction approach to address this challenge. W…
Proposes inference for DNNs in GNRMs, addressing non-independence issues.
problem Inference for DNN-estimated means in GNRMs under non-independence.
method Develops a DNN estimator and ESM for variance estimation and confidence intervals.
result Demonstrates feasibility of inference under GNRMs with ESM.
Study finds racial bias in pulse oximeter readings has minimal impact on ICU ventilation rates.
problem Racial disparities in pulse oximeter readings affect clinical decisions in ICU settings.
method Causal inference using path-specific effects and doubly robust estimator.
result Minimal impact of racial discrepancies on invasive ventilation rates, but more pronounced on ventilation duration.
High-dimensional time series are common in many domains. Since human cognition is not optimized to work well in high-dimensional spaces, these areas could benefit from interpretable low-dimensional representations. However, most representation learning algorithms for time series data are difficult to interpret. This is…
Develops a method to estimate personalized treatment regimes from summary statistics.
problem Estimating optimal treatment regimes for a target population when individual-level data is unavailable.
method A weighting framework that tailors a treatment regime for the target population using summary statistics.
result Consistent and asymptotically normal estimator for optimal treatment regimes.