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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,694 papers · 148 categories

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3570105140 · Jun 202019922001200920172026
48 results for disease root causes

New definition of patient-specific root causes of disease using counterfactuals.

problem Lack of rigorous mathematical formulation for automatic detection of root causes.
method Proposes a counterfactual definition matching clinical intuition and uses Shapley values for causal contribution scores.
result Adapts to disease prevalence, accounts for noisy labels, and admits fast computation.

New model identifies patient-specific disease root causes.

problem Identifying root causes of complex diseases varying between patients.
method Generalized Root Causal Inference (GRCI) algorithm for heteroscedastic noise model.
result GRCI accurately extracts patient-specific root causes.

Identifies patient-specific root causes of disease using structural equation models.

problem Detecting significant variables in complex diseases that differ between patients.
method Defining patient-specific root causes as exogenous errors in a structural equation model, quantifying predictivity using Shapley values, and developing a fast algorithm called Root Causal Inference.
result Significant improvements in accuracy by uncovering root causes with large effect sizes at the individual level but clinically insignificant effect sizes at the group level.

Paper simplifies calculating causation probabilities and ranks root causes.

problem Computational challenges in assessing causal relationships.
method Algorithmic simplifications and novel methodological framework for Root Cause Analysis.
result Significantly reduces computational complexity for calculating causation probabilities.

VEGN uses graph neural networks to predict disease-causing mutations from genetic variants.

problem Identifying disease-causing mutations from millions of genetic variants.
method VEGN employs a graph neural network on a heterogeneous graph of genes and variants, learning gene-gene interactions.
result VEGN outperforms existing state-of-the-art models in variant effect prediction.

Combining forecasts of 16 ED causes improves accuracy and stability.

problem Forecasting accuracy and stability for ED admissions is poor due to model uncertainty and limited data.
method High-dimensional forecast combinations of 16 cause-specific ED forecasts using extensive covariates.
result Forecast combinations yield forecast accuracies of 3.81%-23.54% across causes, outperforming individual models in 50% of scenarios.

New method combines FMEA and Bayesian Network for root cause analysis in lithium-ion battery production.

problem Complex cause-effect relationships in lithium-ion battery production.
method Combining FMEA with Bayesian Network to detect and resolve inconsistencies.
result Holistic method builds large-scale cross-process Bayesian Failure Network for root cause analysis.

Paper adapts causal analysis for time-dependent systems, especially energy management.

problem Challenges in root-cause analysis for systems with lagged time-dependencies, particularly in energy management.
method Adapts causal root-cause analysis method to time-dependent systems, discusses two truncation approaches.
result Extension effectively localizes root-causes in feature and time domain with enough lags.

The technique of Formal Concept Analysis is applied to a dataset describing the traits of rodents, with the goal of identifying zoonotic disease carriers,or those species carrying infections that can spillover to cause human disease. The concepts identified among these species together provide rules-of-thumb about the …

2016-08-25abs ↗pdf ↗

Paper tackles anomaly detection and RCA in dynamical systems using ICODE Networks.

problem Anomalies in dynamical systems impact performance and reliability.
method Proposes ICODE Networks for anomaly detection, RCA, and type classification.
result Demonstrates the ability to accurately detect anomalies, classify types, and pinpoint origins.

CD-RCA method identifies causal relationships in prediction errors without predefined graphs.

problem Challenges in diagnosing prediction errors due to lack of transparency in black-box models.
method Causal-Discovery-based Root-Cause Analysis (CD-RCA) method that estimates causal relationships without predefined causal graphs.
result CD-RCA outperforms heuristic attribution methods in identifying variable contributions to prediction errors.

Deep neural networks (DNNs) are shown to be promising solutions in many challenging artificial intelligence tasks. However, it is very hard to figure out whether the low precision of a DNN model is an inevitable result, or caused by defects. This paper aims at addressing this challenging problem. We find that the inter…

2019-09-05abs ↗pdf ↗

Root Cause Analysis for Anomalies is challenging because of the trade-off between the accuracy and its explanatory friendliness, required for industrial applications. In this paper we propose a framework for simple and friendly RCA within the Bayesian regime under certain restrictions (that Hessian at the mode is diago…

2018-08-13abs ↗pdf ↗

Unlike traditional programs (such as operating systems or word processors) which have large amounts of code, machine learning tasks use programs with relatively small amounts of code (written in machine learning libraries), but voluminous amounts of data. Just like developers of traditional programs debug errors in the…

2016-03-23abs ↗pdf ↗

Study compares machine learning and process-based models for predicting rice blast disease.

problem Predicting rice blast disease to support rice growers in controlling the disease.
method Compared four models: two process-based (Yoshino and WARM) and two machine learning (M5Rules and RNN).
result Machine learning models outperformed process-based models in predicting rice blast disease.

Deep Rule Forests identifies drug-drug and drug-disease interactions causing AKI.

problem Identifying drug-drug and drug-disease interactions leading to AKI.
method Deep Rule Forests (DRF) algorithm discovering rules from multilayer tree models.
result DRF model outperforms other algorithms in prediction accuracy and interpretability.

With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses offers an unprecedented opportunity for studying complex diseases and health conditi…

2019-07-29abs ↗pdf ↗

NetRCA algorithm locates network faults by analyzing derived features and leveraging unlabeled data.

problem Locating the true root cause of network faults is challenging due to complex architectures and limited labeled data.
method NetRCA algorithm extracts derived features, generates new training data, and combines multiple models to enhance performance.
result NetRCA outperforms existing methods in fault cause localization on real-world data.

Machine learning tasks entail the use of complex computational pipelines to reach quantitative and qualitative conclusions. If some of the activities in a pipeline produce erroneous or uninformative outputs, the pipeline may fail or produce incorrect results. Inferring the root cause of failures and unexpected behavior…

2020-02-11abs ↗pdf ↗

AI-assisted heart disease diagnosis reduces misdiagnosis and saves lives.

problem Misdiagnosis of heart disease leads to unnecessary deaths.
method Developed an AI application using ML and DNN algorithms on a dataset from the Cleveland Clinic Foundation.
result DNN model achieved a 92% accuracy rate, reducing misdiagnosis.

We describe a formal approach to identify 'root causes' of outliers observed in nn variables X1,,XnX_1,\dots,X_n in a scenario where the causal relation between the variables is a known directed acyclic graph (DAG). To this end, we first introduce a systematic way to define outlier scores. Further, we introduce the concep…

2019-12-05abs ↗pdf ↗

This study evaluates adversarial attacks and defenses for chest X-ray disease classification.

problem Vulnerability of deep neural networks to adversarial examples in chest X-ray disease detection.
method Detailed introduction and evaluation of various attack and defense methods.
result Attack and defense methods perform poorly with excessive iterations and large perturbations.

Paper tackles RCA in complex networks with unknown interdependencies.

problem Difficult RCA in networked systems due to unknown interdependencies.
method Federated learning for feature-partitioned, nonlinear data without modifying client models.
result Established theoretical convergence guarantees and validated on real-world data.

The paper investigates causal relationships in heart failure prediction using machine learning.

problem Understanding the causal relationships between clinical variables and heart failure.
method Proposes a new computational framework for causal structure discovery (CSD) of mixed-type clinical variables for binary disease outcomes.
result Feature importance from nonlinear classifiers strongly correlates with causal strength of variables, but not differentiating cause and effect.

Heart disease is the leading cause of death, and experts estimate that approximately half of all heart attacks and strokes occur in people who have not been flagged as "at risk." Thus, there is an urgent need to improve the accuracy of heart disease diagnosis. To this end, we investigate the potential of using data ana…

2018-08-22abs ↗pdf ↗

Study proposes deep learning techniques to diagnose and differentiate Celiac Disease and Environmental Enteropathy from biopsy images.

problem Challenging histopathologic overlap between Celiac Disease and Environmental Enteropathy in biopsy images.
method Color balancing and Random Multimodel Deep Learning (RMDL) architecture to address staining variability.
result Proposed deep learning techniques improve diagnosis accuracy of Celiac Disease and Environmental Enteropathy.

Study improves mortality prediction in hospital patients using comprehensive feature engineering.

problem Accurate prediction of all-cause in-hospital mortality in healthcare.
method Comprehensive feature engineering approach using vital signs, laboratory results, and demographic data.
result Random Forest model achieved highest performance with AUC of 0.94, significantly outperforming other models.