Diffusion MRI is the modality of choice to study alterations of white matter. In past years, various works have used diffusion MRI for automatic classification of AD. However, classification performance obtained with different approaches is difficult to compare and these studies are also difficult to reproduce. In the …
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StaPLR improves Alzheimer's disease classification by identifying important MRI scan types and measures.
problem Classifying Alzheimer's disease using multi-source MRI data.
method Stacked penalized logistic regression (StaPLR) with hierarchical multi-view structure and new view importance measure.
result StaPLR identifies the most important MRI scan types and measures for Alzheimer's disease classification.
Background and Purpose: Biopsy is the main determinants of glioma clinical management, but require invasive sampling that fail to detect relevant features because of tumor heterogeneity. The purpose of this study was to evaluate the accuracy of a voxel-wise, multiparametric MRI radiomic method to predict features and d…
Machine learning for ASD diagnosis using morphological MRI networks.
problem Challenging to diagnose ASD using MRI due to heterogeneity and incomplete network neuroscience.
method Crowdsourced Kaggle competition to develop and benchmark ML pipelines.
result First-ranked team achieved 70% accuracy, 72.5% sensitivity, and 67.5% specificity.
Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to tissue microstructure using diffusion MRI. However, it remains unclear which dif…
Purpose: In the present work we describe the correction of diffusion-weighted MRI for site and scanner biases using a novel method based on invariant representation. Theory and Methods: Pooled imaging data from multiple sources are subject to variation between the sources. Correcting for these biases has become very im…
MRI Parameter Mapping via Gaussian Mixture VAE: Breaking the Assumption of Independent Pixelseess.IV
New MRI method maps tissue parameters more accurately by ignoring voxel independence.
problem Voxel independence assumption limits model fitting reliability and repeatability.
method Self-supervised deep variational approach with Gaussian mixture prior.
result Our method outperforms current techniques in dMRI simulations and real data.
Deep model integrates MRI and DTI for autism severity prediction.
problem Predicting spectrum-level deficits in autism using multimodal brain imaging.
method Generative deep-learning framework combining rs-fMRI and DTI data.
result Hybrid model outperforms existing methods in predicting autism severity.
Study evaluates data augmentation methods for prostate cancer detection in MRI.
problem Limited data for prostate cancer detection in MRI.
method Static application of five augmentation techniques (rotation, flip, crop, translation) to MRI dataset.
result Rotation method improved 2D slice-based AUC to 0.85.
We propose to use Gaussian process regression to accurately estimate the diffusion MRI signal at arbitrary locations in q-space. By estimating the signal on a grid, we can do synthetic diffusion spectrum imaging: reconstructing the ensemble averaged propagator (EAP) by an inverse Fourier transform. We also propose an a…
CCDF reduces diffusion sampling steps for inverse problems.
problem Slow sampling from diffusion models in inverse problems.
method Starting from a single forward diffusion step with better initialization, followed by stochastic contraction.
result Significantly reduced sampling steps for state-of-the-art reconstruction.
Tract-specific diffusion measures, as derived from brain diffusion MRI, have been linked to white matter tract structural integrity and neurodegeneration. As a consequence, there is a large interest in the automatic segmentation of white matter tract in diffusion tensor MRI data. Methods based on the tractography are p…
New loss function improves accuracy of MRI parameter estimation.
problem Systematic errors in parameter estimates at low SNR.
method Developed and implemented negative log Rician likelihood (NLR) loss.
result NLR loss shows higher accuracy in parameter estimation than MSE loss at low SNR.
A deep learning framework segments deep cerebellar nuclei from 7T MRI, improving accuracy and consistency.
problem Challenging to accurately segment small deep cerebellar nuclei using standard MRI protocols.
method Proposes DCN-Net, a deep learning framework that encodes contextual information and handles imbalanced data.
result Improves segmentation accuracy and consistency compared to existing methods.
3D CNNs interpret brain MRI differences between men and women.
problem Interpreting 3D CNNs for voxel-wise brain MRI analysis.
method Three interpretation methods: Meaningful Perturbations, Grad CAM, and Guided Backpropagation.
result Voxel-wise 3D CNN interpretation of brain MRI data.
SegAN-CAT improves brain tumor segmentation in MRI using adversarial networks.
problem Improving brain tumor segmentation accuracy in MRI.
method Adversarial Networks, transfer learning, single modality MRI.
result Transfer learning improves single modality MRI segmentation performance.
A new method combines generative and feature-based approaches for unsupervised anomaly detection.
problem Identifying subtle anomalies in test samples compared to a normative distribution.
method A generative cold-diffusion pipeline trained to restore synthetically-corrupted images, combined with a novel synthetic anomaly generation procedure and ensembling restorations.
result Surpasses prior state-of-the-art for unsupervised anomaly detection in three Brain MRI datasets.
Method generates anatomically-controllable medical images with segmentation guidance.
problem Challenging to enforce anatomical constraints in generated medical images.
method Segmentation-guided diffusion models with random mask ablation training.
result New state-of-the-art in faithfulness to input anatomical masks.
Framework integrates brain connectivity data for clinical predictions.
problem Predicting clinical outcomes from brain connectivity data.
method Structurally-regularized Dynamic Dictionary Learning (sr-DDL) and LSTM-ANN block.
result Framework outperforms state-of-the-art approaches in clinical outcome prediction.
Diffusion-weighted magnetic resonance imaging (DWI) and fiber tractography are the only methods to measure the structure of the white matter in the living human brain. The diffusion signal has been modelled as the combined contribution from many individual fascicles of nerve fibers passing through each location in the …
New neural network improves MRI reconstruction for non-Cartesian data.
problem Improving MRI reconstruction for non-Cartesian data acquisitions.
method Density-compensated unrolled neural networks.
result Density-compensated unrolled neural networks outperform baselines.
In this paper, we address the problem of synthesizing multi-parameter magnetic resonance imaging (mp-MRI) data, i.e. Apparent Diffusion Coefficients (ADC) and T2-weighted (T2w), containing clinically significant (CS) prostate cancer (PCa) via semi-supervised adversarial learning. Specifically, our synthesizer generates…
Deep learning improves MRI image quality from down-sampled data.
problem Improving MRI image quality from accelerated, down-sampled k-space data.
method Deep Residual Dense U-Net architecture with Residual Dense Block and new loss function.
result The proposed method achieves better performance in reconstructing high-quality images from down-sampled k-space data.
Ischaemic stroke is a medical condition caused by occlusion of blood supply to the brain tissue thus forming a lesion. A lesion is zoned into a core associated with irreversible necrosis typically located at the center of the lesion, while reversible hypoxic changes in the outer regions of the lesion are termed as the …
Synthetic learning improves neonatal brain MRI segmentation robustness.
problem Challenges in neonatal brain MRI segmentation due to image contrast and anatomical variations.
method Synthetic learning model trained on few T2-weighted volumes, then enhanced with motion artifacts and over-segmentation.
result Synthetic learning robust to image contrast and improves segmentation of both T1- and T2-weighted images.
PnP-CM integrates CMs into PnP frameworks for efficient inverse problem solving.
problem Efficiently solving inverse problems with high-quality reconstructions.
method Reinterpreting CMs as proximal operators and integrating them into PnP frameworks.
result PnP-CM achieves high-quality reconstructions in as few as 4 NFEs.
SFCNeXt estimates brain age from small MRI datasets.
problem Efficiently estimating brain age from limited MRI data.
method Simple fully convolutional network (SFCNeXt) with SPEC and HRL.
result SFCNeXt outperforms complex models in small sample size scenarios.
Combining diffusion models with Langevin dynamics improves posterior sampling efficiency.
problem Sampling from noisy posterior distributions efficiently.
method Annealed Langevin dynamics combined with diffusion models.
result Achieves posterior sampling in polynomial time with a weaker score error bound.
NAS improves gliomas segmentation on MRI scans.
problem Designing optimal deep learning architectures for brain tumor segmentation.
method Neural architecture search with probabilistic parameter learning for MRI brain tumor segmentation.
result Two optimal neural architectures for brain tumor segmentation were discovered.
Efficiently clusters nodes in Gaussian graphical models from data.
problem Clustering nodes in Gaussian graphical models directly from data.
method Clusters nodes based on the similarity of their network neighborhoods defined by partial correlations. Uses matrix factors for limited data.
result Demonstrates improved clustering of nodes in Gaussian graphical models.
Total variation regularization and total variation flows (TVF) have been widely applied for image enhancement and denoising. To include a generic preservation of crossing curvilinear structures in TVF we lift images to the homogeneous space of positions and orientations as a Lie group…
Posterior sampling from diffusion models is computationally hard.
problem Sampling from posterior distributions in diffusion models is intractable.
method Analyzes the computational complexity of posterior sampling in diffusion models.
result Posterior sampling is computationally intractable under cryptographic assumptions.
A new method for offline RL using diffusion models and self-weighted guidance.
problem Challenges in computing scores for offline RL using weight functions.
method Constructing a diffusion over actions and weights, using the diffusion model for guidance.
result Performs on par with state-of-the-art methods on challenging environments.
A Lagrangian perspective on nonautonomous advection-diffusion processes in the low-diffusivity limitmath.AP
Study mass transport in low-diffusivity using Lagrangian coordinates.
problem Mass preserving transport of passive tracers in low-diffusivity limit.
method Lagrangian coordinates, time-averaged diffusion equation, weighted manifold structure.
result Leading order asymptotics extend to dominant nontrivial singular value in low-diffusivity limit.
New method captures multimodal disconnectivity in schizophrenia.
problem Misinterpretation of single modality data in schizophrenia research.
method Gaussian graphical model and modularity-based approach on multimodal data.
result Identifies missing links in schizophrenia's default mode network.
Diffusion models optimize objectives similar to ELBO with Gaussian noise augmentation.
problem Optimizing diffusion models for high perceptual quality.
method Showed diffusion objectives are weighted ELBOs over noise levels, with Gaussian noise augmentation.
result Diffusion objectives equate to ELBO with Gaussian noise augmentation under monotonic weighting.
Paper proposes a neural network for estimating brain conductivity without segmentation.
problem Accurate head model generation for personalized TMS with realistic conductivity.
method Convolutional neural network estimating conductivity from MRI data.
result Smooth electric field results similar to conventional methods without segmentation.
This letter presents an improved version of diffusion least mean ppower (LMP) algorithm for distributed estimation. Instead of sum of mean square errors, a weighted sum of mean square error is defined as the cost function for global and local cost functions of a network of sensors. The weight coefficients are updated b…
Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and treatments of neurological disorders and a deeper understanding of the human brain. R…
Diffusion models accurately recover mixture weights from generated samples despite score function insensitivity.
problem Score-based generative models often fail to learn correct relative mode amplitudes (mixture weights) from generated samples.
method Relate diffusion score matching (DSM) loss to mixture weight estimation error, define diffusion score sensitivity index (DSSI), and prove its governing role in mixture weight recovery.
result Generated samples can accurately recover mixture weights from the DSM loss, even when the target score is insensitive to mixture weights.
Smile-GANs clusters brain MRI scans to reveal disease subtypes and progression.
problem Understanding disease heterogeneity in brain MRI scans.
method Generative Adversarial Networks (GANs) for semi-supervised clustering.
result Discovered four subtypes of Alzheimer's and prodromal phases, with two progressive pathways.
A benchmark evaluates ioUS-to-MR synthesis methods for brain tumor surgery.
problem Difficult interpretation of ioUS images for brain tumor surgery.
method Six generators trained under four inference regimes and two targets on public data.
result SynDiff-2.5D best preserved downstream segmentation (U_Dice=0.55).
XPDNet wins MRI reconstruction challenge with neural network.
problem MRI reconstruction from under-sampled data.
method Inspired by MRI and computer vision best practices, XPDNet uses a neural network.
result XPDNet achieved state-of-the-art results in the 2020 fastMRI challenge.
A new diffusion sampling method combines Krylov subspace and diffusion models for faster and more efficient inverse problems.
problem Efficiently solving large-scale inverse problems in high-performance computing.
method Proposes a novel diffusion sampling strategy that integrates Krylov subspace methods with diffusion models.
result Demonstrates significant speedup (80x faster inference time) and improved reconstruction quality on real-world medical imaging problems.
-net: Ensembled Iterative Deep Neural Networks for Accelerated Parallel MR Image Reconstructioneess.IV
Ensembled neural networks improve MRI image quality.
problem Accelerated parallel MR imaging with high SSIM scores.
method Ensembled -net combining parallel coil and sensitivity networks, trained with supervised and semi-supervised methods.
result Ensembling models achieves visually sharp and textured images with robust SSIM scores.
Generative adversarial networks reconstruct MRI images without full data.
problem Lack of fully-sampled ground truth data for supervised MRI reconstruction.
method Generative adversarial networks for unsupervised MRI reconstruction.
result Reconstructed images show more anatomical structure than conventional methods.
Estimates localized complexity of white-matter wiring using GANs.
problem Complexity of white-matter wiring, especially in ambiguous regions, confounds analysis.
method Bayesian estimate of heteroscedastic aleatoric uncertainty through image inpainting.
result Localized wiring complexity quantified, directly reflecting difficulty of lesion inpainting.
Acquisition of Magnetic Resonance Imaging (MRI) scans can be accelerated by under-sampling in k-space (i.e., the Fourier domain). In this paper, we consider the problem of optimizing the sub-sampling pattern in a data-driven fashion. Since the reconstruction model's performance depends on the sub-sampling pattern, we c…