Novel 3D U-Net method for fast, reproducible white matter tract segmentation.
problem Challenges in fast and consistent white matter tract segmentation from diffusion tensor MRI.
method Convolutional neural network (3D U-Net) trained on a large DTI dataset.
result Reproducibility and accuracy of tract-specific diffusion measures.
Deep model integrates MRI and DTI for autism severity prediction.
problem Predicting spectrum-level deficits in autism using multimodal brain imaging.
method Generative deep-learning framework combining rs-fMRI and DTI data.
result Hybrid model outperforms existing methods in predicting autism severity.
3D CNNs interpret brain MRI differences between men and women.
problem Interpreting 3D CNNs for voxel-wise brain MRI analysis.
method Three interpretation methods: Meaningful Perturbations, Grad CAM, and Guided Backpropagation.
result Voxel-wise 3D CNN interpretation of brain MRI data.
Diffusion MRI is the modality of choice to study alterations of white matter. In past years, various works have used diffusion MRI for automatic classification of AD. However, classification performance obtained with different approaches is difficult to compare and these studies are also difficult to reproduce. In the …
Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to tissue microstructure using diffusion MRI. However, it remains unclear which dif…
New MRI method maps tissue parameters more accurately by ignoring voxel independence.
problem Voxel independence assumption limits model fitting reliability and repeatability.
method Self-supervised deep variational approach with Gaussian mixture prior.
result Our method outperforms current techniques in dMRI simulations and real data.
Framework integrates brain connectivity data for clinical predictions.
problem Predicting clinical outcomes from brain connectivity data.
method Structurally-regularized Dynamic Dictionary Learning (sr-DDL) and LSTM-ANN block.
result Framework outperforms state-of-the-art approaches in clinical outcome prediction.
We propose to use Gaussian process regression to accurately estimate the diffusion MRI signal at arbitrary locations in q-space. By estimating the signal on a grid, we can do synthetic diffusion spectrum imaging: reconstructing the ensemble averaged propagator (EAP) by an inverse Fourier transform. We also propose an a…
THS-GAN uses tensorizing and high-order pooling for AD diagnosis.
problem Early diagnosis of Alzheimer's Disease (AD) using MRI images.
method Tensorizing a three-player cooperative game framework with high-order pooling for MRI images.
result THS-GAN achieves superior performance in AD diagnosis compared to existing methods.
CCDF reduces diffusion sampling steps for inverse problems.
problem Slow sampling from diffusion models in inverse problems.
method Starting from a single forward diffusion step with better initialization, followed by stochastic contraction.
result Significantly reduced sampling steps for state-of-the-art reconstruction.
New loss function improves accuracy of MRI parameter estimation.
problem Systematic errors in parameter estimates at low SNR.
method Developed and implemented negative log Rician likelihood (NLR) loss.
result NLR loss shows higher accuracy in parameter estimation than MSE loss at low SNR.
StaPLR improves Alzheimer's disease classification by identifying important MRI scan types and measures.
problem Classifying Alzheimer's disease using multi-source MRI data.
method Stacked penalized logistic regression (StaPLR) with hierarchical multi-view structure and new view importance measure.
result StaPLR identifies the most important MRI scan types and measures for Alzheimer's disease classification.
A deep learning framework segments deep cerebellar nuclei from 7T MRI, improving accuracy and consistency.
problem Challenging to accurately segment small deep cerebellar nuclei using standard MRI protocols.
method Proposes DCN-Net, a deep learning framework that encodes contextual information and handles imbalanced data.
result Improves segmentation accuracy and consistency compared to existing methods.
Proposes CC-NMDF for analyzing manifold-valued data.
problem Nonlinear structure in manifold-valued data requires new analysis methods.
method Curvature-corrected nonnegative manifold data factorization (CC-NMDF) with an iterative algorithm.
result Demonstrates CC-NMDF on real-world diffusion tensor MRI data.
Purpose: In the present work we describe the correction of diffusion-weighted MRI for site and scanner biases using a novel method based on invariant representation. Theory and Methods: Pooled imaging data from multiple sources are subject to variation between the sources. Correcting for these biases has become very im…
CNNs achieve remarkable performance by leveraging deep, over-parametrized architectures, trained on large datasets. However, they have limited generalization ability to data outside the training domain, and a lack of robustness to noise and adversarial attacks. By building better inductive biases, we can improve robust…
Diffusion-weighted magnetic resonance imaging (DWI) and fiber tractography are the only methods to measure the structure of the white matter in the living human brain. The diffusion signal has been modelled as the combined contribution from many individual fascicles of nerve fibers passing through each location in the …
A new method combines generative and feature-based approaches for unsupervised anomaly detection.
problem Identifying subtle anomalies in test samples compared to a normative distribution.
method A generative cold-diffusion pipeline trained to restore synthetically-corrupted images, combined with a novel synthetic anomaly generation procedure and ensembling restorations.
result Surpasses prior state-of-the-art for unsupervised anomaly detection in three Brain MRI datasets.
Method generates anatomically-controllable medical images with segmentation guidance.
problem Challenging to enforce anatomical constraints in generated medical images.
method Segmentation-guided diffusion models with random mask ablation training.
result New state-of-the-art in faithfulness to input anatomical masks.
Streaming tensor factorization is a powerful tool for processing high-volume and multi-way temporal data in Internet networks, recommender systems and image/video data analysis. Existing streaming tensor factorization algorithms rely on least-squares data fitting and they do not possess a mechanism for tensor rank dete…
A new tensor decomposition method for fMRI data captures both spatial and temporal variability.
problem Challenges in modeling shared and subject-specific structure in multisubject spatiotemporal data, especially in neuroimaging.
method Introduces a spatiotemporal variational tensor decomposition (ST-VTD) framework combining tensor factorization with structured priors for flexible representation of spatial and temporal dynamics.
result Significantly improves latent factor recovery in fMRI data compared to classical and probabilistic decomposition benchmarks.
DeepTensor uses deep networks to efficiently decompose tensors with improved performance and robustness.
problem Efficiently decomposing tensors with deep learning to capture nonlinear structures.
method Low-rank tensor decomposition using deep generative networks trained to minimize approximation error.
result DeepTensor outperforms classical methods like SVD and PCA in various applications, including image denoising and 3D MRI.
Diffusion MRI (dMRI) provides the ability to reconstruct neuronal fibers in the brain, in vivo, by measuring water diffusion along angular gradient directions in q-space. High angular resolution diffusion imaging (HARDI) can produce better estimates of fiber orientation than the popularly used diffusion tens…
Machine learning for ASD diagnosis using morphological MRI networks.
problem Challenging to diagnose ASD using MRI due to heterogeneity and incomplete network neuroscience.
method Crowdsourced Kaggle competition to develop and benchmark ML pipelines.
result First-ranked team achieved 70% accuracy, 72.5% sensitivity, and 67.5% specificity.
A new diffusion model generates structured tensors for high-dimensional data.
problem Generating a structured tensor with a target distribution.
method Tucker diffusion model with Tucker-Unet architecture.
result Generated tensors converge to the true data distribution at a rate dependent on tensor mode dimensions.
DEMOTE uses neural diffusion-reaction processes to capture temporal dynamics in sparse tensor data.
problem Sparse and temporally associated tensor data with limited structural knowledge.
method Develops a neural diffusion-reaction process to estimate dynamic embeddings for tensor modes.
result Captures both commonalities and personalities in evolving tensor entries.
Enhances geodesic fiber tracking in white matter using modified metrics and tensor data.
problem Improving the accuracy and robustness of geodesic fiber tracking in white matter.
method Modification of geodesic ray-tracing method using rescaled metrics and fourth-order tensor data.
result More satisfactory results in the construction of white matter tracts as geodesics.
Study evaluates data augmentation methods for prostate cancer detection in MRI.
problem Limited data for prostate cancer detection in MRI.
method Static application of five augmentation techniques (rotation, flip, crop, translation) to MRI dataset.
result Rotation method improved 2D slice-based AUC to 0.85.
InVA models image outcomes from multiple modalities, outperforming standard VAEs.
problem Understanding relationships across multiple imaging modalities in neuroimaging.
method Integrative Variational Autoencoder (InVA) framework for image-on-image regression.
result InVA accurately predicts PET scans from structural MRI, outperforming conventional models.
PnP-CM integrates CMs into PnP frameworks for efficient inverse problem solving.
problem Efficiently solving inverse problems with high-quality reconstructions.
method Reinterpreting CMs as proximal operators and integrating them into PnP frameworks.
result PnP-CM achieves high-quality reconstructions in as few as 4 NFEs.
High-dimensional tensors or multi-way data are becoming prevalent in areas such as biomedical imaging, chemometrics, networking and bibliometrics. Traditional approaches to finding lower dimensional representations of tensor data include flattening the data and applying matrix factorizations such as principal component…
Background and Purpose: Biopsy is the main determinants of glioma clinical management, but require invasive sampling that fail to detect relevant features because of tumor heterogeneity. The purpose of this study was to evaluate the accuracy of a voxel-wise, multiparametric MRI radiomic method to predict features and d…
Statistical analysis of Diffusion Tensor Imaging (DTI) data requires a computational framework that is both numerically tractable (to account for the high dimensional nature of the data) and geometric (to account for the nonlinear nature of diffusion tensors). Building upon earlier studies that have shown that a Rieman…
Combining diffusion models with Langevin dynamics improves posterior sampling efficiency.
problem Sampling from noisy posterior distributions efficiently.
method Annealed Langevin dynamics combined with diffusion models.
result Achieves posterior sampling in polynomial time with a weaker score error bound.
KReTTaH uses tensor trains and Hadamard overparameterization for fast, interpretable multi-way data imputation.
problem Multi-way data imputation for high-dimensional functional MRI and dynamic graph recovery.
method Reformulates imputation as RKHS regression with TT-constrained coefficients and Hadamard overparameterization. Optimizes TT coefficients and kernel matrices on Riemannian manifolds.
result Consistently outperforms state-of-the-art methods in modeling accuracy.
KReTTaH uses tensor trains and Hadamard overparameterization for fast, interpretable multi-way data imputation.
problem Multi-way data imputation in high-dimensional spaces.
method Reformulates imputation as RKHS regression with TT-constrained coefficients, optimized on manifold frameworks.
result Consistently outperforms state-of-the-art methods in accuracy.
Extends multivariate regression for tensor-variate data, identifying brain regions and facial characteristics.
problem Challenges in fitting regression models with multivariate responses and covariates.
method Low-rank tensor formats on regression coefficients and tensor-variate normal distribution for errors.
result Maximum likelihood estimators for tensor-on-tensor regression via block-relaxation algorithms.
Posterior sampling from diffusion models is computationally hard.
problem Sampling from posterior distributions in diffusion models is intractable.
method Analyzes the computational complexity of posterior sampling in diffusion models.
result Posterior sampling is computationally intractable under cryptographic assumptions.
Total variation regularization and total variation flows (TVF) have been widely applied for image enhancement and denoising. To include a generic preservation of crossing curvilinear structures in TVF we lift images to the homogeneous space M=Rd⋊Sd−1 of positions and orientations as a Lie group…
DKN adapts to medical imaging data with limited samples and interpretable models.
problem Medical imaging data's unique nature makes general methods like CNN unsuitable.
method DKN uses a Kronecker product structure to adapt to low sample size and provide interpretable models.
result DKN achieves prediction power comparable to CNN and provides model interpretability.
In many problems of supervised tensor learning (STL), real world data such as face images or MRI scans are naturally represented as matrices, which are also called as second order tensors. Most existing classifiers based on tensor representation, such as support tensor machine (STM) need to solve iteratively which occu…
New method captures multimodal disconnectivity in schizophrenia.
problem Misinterpretation of single modality data in schizophrenia research.
method Gaussian graphical model and modularity-based approach on multimodal data.
result Identifies missing links in schizophrenia's default mode network.
Current high-throughput data acquisition technologies probe dynamical systems with different imaging modalities, generating massive data sets at different spatial and temporal resolutions posing challenging problems in multimodal data fusion. A case in point is the attempt to parse out the brain structures and networks…
Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and treatments of neurological disorders and a deeper understanding of the human brain. R…
New method infers diffusion equations from sparse data.
problem Statistical inference of diffusion equations from limited data.
method Neural network-based estimators for drift and diffusion tensor.
result Statistical convergence guarantees for Hölder continuous processes.
Smile-GANs clusters brain MRI scans to reveal disease subtypes and progression.
problem Understanding disease heterogeneity in brain MRI scans.
method Generative Adversarial Networks (GANs) for semi-supervised clustering.
result Discovered four subtypes of Alzheimer's and prodromal phases, with two progressive pathways.
A benchmark evaluates ioUS-to-MR synthesis methods for brain tumor surgery.
problem Difficult interpretation of ioUS images for brain tumor surgery.
method Six generators trained under four inference regimes and two targets on public data.
result SynDiff-2.5D best preserved downstream segmentation (U_Dice=0.55).
A new diffusion sampling method combines Krylov subspace and diffusion models for faster and more efficient inverse problems.
problem Efficiently solving large-scale inverse problems in high-performance computing.
method Proposes a novel diffusion sampling strategy that integrates Krylov subspace methods with diffusion models.
result Demonstrates significant speedup (80x faster inference time) and improved reconstruction quality on real-world medical imaging problems.