Diffusion MRI is the modality of choice to study alterations of white matter. In past years, various works have used diffusion MRI for automatic classification of AD. However, classification performance obtained with different approaches is difficult to compare and these studies are also difficult to reproduce. In the …
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48 results for “diffusion MRI”
Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to tissue microstructure using diffusion MRI. However, it remains unclear which dif…
MRI Parameter Mapping via Gaussian Mixture VAE: Breaking the Assumption of Independent Pixelseess.IV
New MRI method maps tissue parameters more accurately by ignoring voxel independence.
problem Voxel independence assumption limits model fitting reliability and repeatability.
method Self-supervised deep variational approach with Gaussian mixture prior.
result Our method outperforms current techniques in dMRI simulations and real data.
We propose to use Gaussian process regression to accurately estimate the diffusion MRI signal at arbitrary locations in q-space. By estimating the signal on a grid, we can do synthetic diffusion spectrum imaging: reconstructing the ensemble averaged propagator (EAP) by an inverse Fourier transform. We also propose an a…
CCDF reduces diffusion sampling steps for inverse problems.
problem Slow sampling from diffusion models in inverse problems.
method Starting from a single forward diffusion step with better initialization, followed by stochastic contraction.
result Significantly reduced sampling steps for state-of-the-art reconstruction.
Tract-specific diffusion measures, as derived from brain diffusion MRI, have been linked to white matter tract structural integrity and neurodegeneration. As a consequence, there is a large interest in the automatic segmentation of white matter tract in diffusion tensor MRI data. Methods based on the tractography are p…
New loss function improves accuracy of MRI parameter estimation.
problem Systematic errors in parameter estimates at low SNR.
method Developed and implemented negative log Rician likelihood (NLR) loss.
result NLR loss shows higher accuracy in parameter estimation than MSE loss at low SNR.
StaPLR improves Alzheimer's disease classification by identifying important MRI scan types and measures.
problem Classifying Alzheimer's disease using multi-source MRI data.
method Stacked penalized logistic regression (StaPLR) with hierarchical multi-view structure and new view importance measure.
result StaPLR identifies the most important MRI scan types and measures for Alzheimer's disease classification.
A deep learning framework segments deep cerebellar nuclei from 7T MRI, improving accuracy and consistency.
problem Challenging to accurately segment small deep cerebellar nuclei using standard MRI protocols.
method Proposes DCN-Net, a deep learning framework that encodes contextual information and handles imbalanced data.
result Improves segmentation accuracy and consistency compared to existing methods.
3D CNNs interpret brain MRI differences between men and women.
problem Interpreting 3D CNNs for voxel-wise brain MRI analysis.
method Three interpretation methods: Meaningful Perturbations, Grad CAM, and Guided Backpropagation.
result Voxel-wise 3D CNN interpretation of brain MRI data.
Purpose: In the present work we describe the correction of diffusion-weighted MRI for site and scanner biases using a novel method based on invariant representation. Theory and Methods: Pooled imaging data from multiple sources are subject to variation between the sources. Correcting for these biases has become very im…
A new method combines generative and feature-based approaches for unsupervised anomaly detection.
problem Identifying subtle anomalies in test samples compared to a normative distribution.
method A generative cold-diffusion pipeline trained to restore synthetically-corrupted images, combined with a novel synthetic anomaly generation procedure and ensembling restorations.
result Surpasses prior state-of-the-art for unsupervised anomaly detection in three Brain MRI datasets.
Method generates anatomically-controllable medical images with segmentation guidance.
problem Challenging to enforce anatomical constraints in generated medical images.
method Segmentation-guided diffusion models with random mask ablation training.
result New state-of-the-art in faithfulness to input anatomical masks.
Deep model integrates MRI and DTI for autism severity prediction.
problem Predicting spectrum-level deficits in autism using multimodal brain imaging.
method Generative deep-learning framework combining rs-fMRI and DTI data.
result Hybrid model outperforms existing methods in predicting autism severity.
Machine learning for ASD diagnosis using morphological MRI networks.
problem Challenging to diagnose ASD using MRI due to heterogeneity and incomplete network neuroscience.
method Crowdsourced Kaggle competition to develop and benchmark ML pipelines.
result First-ranked team achieved 70% accuracy, 72.5% sensitivity, and 67.5% specificity.
Study evaluates data augmentation methods for prostate cancer detection in MRI.
problem Limited data for prostate cancer detection in MRI.
method Static application of five augmentation techniques (rotation, flip, crop, translation) to MRI dataset.
result Rotation method improved 2D slice-based AUC to 0.85.
PnP-CM integrates CMs into PnP frameworks for efficient inverse problem solving.
problem Efficiently solving inverse problems with high-quality reconstructions.
method Reinterpreting CMs as proximal operators and integrating them into PnP frameworks.
result PnP-CM achieves high-quality reconstructions in as few as 4 NFEs.
Background and Purpose: Biopsy is the main determinants of glioma clinical management, but require invasive sampling that fail to detect relevant features because of tumor heterogeneity. The purpose of this study was to evaluate the accuracy of a voxel-wise, multiparametric MRI radiomic method to predict features and d…
Combining diffusion models with Langevin dynamics improves posterior sampling efficiency.
problem Sampling from noisy posterior distributions efficiently.
method Annealed Langevin dynamics combined with diffusion models.
result Achieves posterior sampling in polynomial time with a weaker score error bound.
Total variation regularization and total variation flows (TVF) have been widely applied for image enhancement and denoising. To include a generic preservation of crossing curvilinear structures in TVF we lift images to the homogeneous space of positions and orientations as a Lie group…
Posterior sampling from diffusion models is computationally hard.
problem Sampling from posterior distributions in diffusion models is intractable.
method Analyzes the computational complexity of posterior sampling in diffusion models.
result Posterior sampling is computationally intractable under cryptographic assumptions.
Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and treatments of neurological disorders and a deeper understanding of the human brain. R…
Smile-GANs clusters brain MRI scans to reveal disease subtypes and progression.
problem Understanding disease heterogeneity in brain MRI scans.
method Generative Adversarial Networks (GANs) for semi-supervised clustering.
result Discovered four subtypes of Alzheimer's and prodromal phases, with two progressive pathways.
XPDNet wins MRI reconstruction challenge with neural network.
problem MRI reconstruction from under-sampled data.
method Inspired by MRI and computer vision best practices, XPDNet uses a neural network.
result XPDNet achieved state-of-the-art results in the 2020 fastMRI challenge.
A benchmark evaluates ioUS-to-MR synthesis methods for brain tumor surgery.
problem Difficult interpretation of ioUS images for brain tumor surgery.
method Six generators trained under four inference regimes and two targets on public data.
result SynDiff-2.5D best preserved downstream segmentation (U_Dice=0.55).
Framework integrates brain connectivity data for clinical predictions.
problem Predicting clinical outcomes from brain connectivity data.
method Structurally-regularized Dynamic Dictionary Learning (sr-DDL) and LSTM-ANN block.
result Framework outperforms state-of-the-art approaches in clinical outcome prediction.
A new diffusion sampling method combines Krylov subspace and diffusion models for faster and more efficient inverse problems.
problem Efficiently solving large-scale inverse problems in high-performance computing.
method Proposes a novel diffusion sampling strategy that integrates Krylov subspace methods with diffusion models.
result Demonstrates significant speedup (80x faster inference time) and improved reconstruction quality on real-world medical imaging problems.
Generative adversarial networks reconstruct MRI images without full data.
problem Lack of fully-sampled ground truth data for supervised MRI reconstruction.
method Generative adversarial networks for unsupervised MRI reconstruction.
result Reconstructed images show more anatomical structure than conventional methods.
Study identifies five AD subtypes using graph diffusion and similarity learning.
problem Identifying homogeneous AD subtypes to improve diagnosis and treatment.
method Unsupervised clustering with graph diffusion and similarity learning.
result Five distinct AD subtypes identified with significant differences in biomarkers and clinical features.
Objective: Multimodal measurements of the same phenomena provide complementary information and highlight different perspectives, albeit each with their own limitations. A focus on a single modality may lead to incorrect inferences, which is especially important when a studied phenomenon is a disease. In this paper, we …
Deep learning (DL) has shown great potential in medical image enhancement problems, such as super-resolution or image synthesis. However, to date, little consideration has been given to uncertainty quantification over the output image. Here we introduce methods to characterise different components of uncertainty in suc…
Human brain development is rapid during infancy and early childhood. Many disease processes impair this development. Therefore, brain developmental age estimation (BDAE) is essential for all diseases affecting cognitive development. Brain magnetic resonance imaging (MRI) of infants shows brain growth and morphologic pa…
In this paper, we address the problem of synthesizing multi-parameter magnetic resonance imaging (mp-MRI) data, i.e. Apparent Diffusion Coefficients (ADC) and T2-weighted (T2w), containing clinically significant (CS) prostate cancer (PCa) via semi-supervised adversarial learning. Specifically, our synthesizer generates…
Clustering is concerned with coherently grouping observations without any explicit concept of true groupings. Spectral graph clustering - clustering the vertices of a graph based on their spectral embedding - is commonly approached via K-means (or, more generally, Gaussian mixture model) clustering composed with either…
Diffusion MRI (dMRI) provides the ability to reconstruct neuronal fibers in the brain, , by measuring water diffusion along angular gradient directions in q-space. High angular resolution diffusion imaging (HARDI) can produce better estimates of fiber orientation than the popularly used diffusion tens…
CSGM framework applied to clinical MRI data for robust reconstructions.
problem Applying deep generative priors to clinical MRI data for high-quality reconstructions.
method Training a generative prior on brain scans from the fastMRI dataset and using Langevin dynamics for posterior sampling.
result Posterior sampling via Langevin dynamics achieves high quality reconstructions in clinical MRI data.
New neural network improves MRI reconstruction for non-Cartesian data.
problem Improving MRI reconstruction for non-Cartesian data acquisitions.
method Density-compensated unrolled neural networks.
result Density-compensated unrolled neural networks outperform baselines.
This study improves lung tumor segmentation in mice MRI scans with nnU-Net, reducing annotation needs.
problem Accurate lung tumor segmentation in mice MRI scans for drug discovery.
method Optimized nnU-Net 3D model for lung tumor segmentation with minimal annotations.
result nnU-Net 3D models outperform 2D models in MRI mice scans, requiring fewer annotations.
In compressed sensing MRI (CS-MRI), k-space measurements are under-sampled to achieve accelerated scan times. CS-MRI presents two fundamental problems: (1) where to sample and (2) how to reconstruct an under-sampled scan. In this paper, we tackle both problems simultaneously for the specific case of 2D Cartesian sampli…
Accelerating Magnetic Resonance Imaging (MRI) by taking fewer measurements has the potential to reduce medical costs, minimize stress to patients and make MRI possible in applications where it is currently prohibitively slow or expensive. We introduce the fastMRI dataset, a large-scale collection of both raw MR measure…
New method MRI improves machine learning models' ability to generalize to unseen data.
problem Machine learning models often fail to generalize well to out-of-distribution data.
method Introduces a new notion of invariance (MRI) and a practical version (MRI-v1) to improve model generalization.
result MRI-v1 guarantees invariant predictors and outperforms IRM-v1 in various settings.
New method optimizes MRI sampling patterns for faster scans.
problem Accelerate MRI scans without sacrificing image quality.
method Joint learning of adaptive sampling patterns and model-based recovery.
result Improved MR image quality compared to other methods.
Magnetic resonance imaging (MRI) is widely used in clinical practice, but it has been traditionally limited by its slow data acquisition. Recent advances in compressed sensing (CS) techniques for MRI reduce acquisition time while maintaining high image quality. Whereas classical CS assumes the images are sparse in know…
Deep learning improves MRI analysis of MSK disorders.
problem Accurate and rapid analysis of musculoskeletal disorders from MRI scans.
method Convolutional neural networks (CNN) for automatic classification of knee abnormalities.
result Multi-view deep learning showed promising performance in classifying MSK abnormalities.
A central question for active learning (AL) is: "what is the optimal selection?" Defining optimality by classifier loss produces a new characterisation of optimal AL behaviour, by treating expected loss reduction as a statistical target for estimation. This target forms the basis of model retraining improvement (MRI), …
SrvfNet aligns multiple functional data to templates without supervision.
problem Aligning large collections of functional data to templates without labeled data.
method Generative deep learning framework using SRVF and fully-connected layers.
result Framework achieves alignment and optimal template prediction without supervision.
Use expert visualization or conventional clinical indices can lack accuracy for borderline classications. Advanced statistical approaches based on eigen-decomposition have been mostly concerned with shape and motion indices. In this paper, we present a new approach to identify CVDs from cine-MRI by estimating large poo…
Image reconstruction from undersampled k-space data has been playing an important role for fast MRI. Recently, deep learning has demonstrated tremendous success in various fields and also shown potential to significantly speed up MR reconstruction with reduced measurements. This article gives an overview of deep learni…