We consider the problem of locating a point-source heart arrhythmia using data from a standard diagnostic procedure, where a reference catheter is placed in the heart, and arrival times from a second diagnostic catheter are recorded as the diagnostic catheter moves around within the heart. We model this situation as a …
Many iterative procedures in stochastic optimization exhibit a transient phase followed by a stationary phase. During the transient phase the procedure converges towards a region of interest, and during the stationary phase the procedure oscillates in that region, commonly around a single point. In this paper, we devel…
AI predicts medical specialty diagnostic choices from EHR records.
problem Predicting timely medical specialty diagnostic workups for patients.
method Ensemble of feed-forward neural networks trained on EHR data.
result Significantly higher accuracy compared to traditional checklists.
The paper analyzes numerical instability in variational flows and proposes a diagnostic method.
problem Numerical instability in variational flows affects sampling, density evaluation, and ELBO estimation.
method Treated variational flows as dynamical systems, used shadowing theory for theoretical guarantees, and developed a diagnostic procedure.
result Despite numerical instability, results from variational flows can be accurate enough for practical applications.
The paper analyzes convergence in SGD with momentum and proposes a diagnostic test.
problem Detecting convergence in stochastic gradient descent with momentum.
method Analyzes the transient and stationary phases of SGD with momentum, constructs a statistical diagnostic test.
result The proposed diagnostic test effectively detects convergence in the stationary phase of SGD with momentum.
Paper proposes a coupling-based diagnostic for SGD stepsize optimization.
problem Optimizing stepsize for SGD convergence.
method Coupling-based convergence diagnostic for monitoring stationarity.
result Proposed stepsize scheme achieves superior performance across convex and non-convex problems.
Computer vision model automates residual plot assessment for diagnosing model assumptions.
problem Automating residual plot assessment for model diagnostics.
method Trains a computer vision model to predict disparity between residual distributions and reference distributions using Kullback-Leibler divergence.
result Computer vision model is less sensitive to non-linearity but more sensitive than human judgment and conventional tests.
Paper proposes a new method to detect convergence in SGD.
problem Detecting the transition from fast progress to oscillation in SGD.
method Analyzes Pflug's test and proposes a novel statistical procedure.
result The novel procedure accurately detects stationarity in SGD.
Major advances have been made regarding the utilization of artificial intelligence in health care. In particular, deep learning approaches have been successfully applied for automated and assisted disease diagnosis and prognosis based on complex and high-dimensional data. However, despite all justified enthusiasm, over…
New diagnostics detect variability in individual risk estimates from machine learning models in healthcare.
problem Variability in individual risk estimates from machine learning models in healthcare, leading to unreliable treatment decisions.
method Proposed evaluation framework using empirical prediction interval width and empirical decision flip rate diagnostics.
result Randomness in optimization and initialization can lead to substantial individual-level variability in risk estimates, affecting clinical decisions.
The hybrid clustering-classification neural network is proposed. This network allows increasing a quality of information processing under the condition of overlapping classes due to the rational choice of a learning rate parameter and introducing a special procedure of fuzzy reasoning in the clustering process, which o…
Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus call for a higher-integrated AI-based diagnostic algorithm. Methods: In this pape…
This paper develops a Bayesian procedure for estimation and forecasting of the volatility of multivariate time series. The foundation of this work is the matrix-variate dynamic linear model, for the volatility of which we adopt a multiplicative stochastic evolution, using Wishart and singular multivariate beta distribu…
DECAT framework evaluates multimodal models for shared biology, detecting confounders and false positives.
problem Determining if multimodal models learn shared biology or just confounders.
method DECAT framework classifies multimodal representations into four diagnostic scenarios using null-referenced metrics.
result DECAT detects confounders and false positives in multimodal models, improving with larger cohorts and stronger representations.
New method predicts y distributions from imperfect data.
problem Predicting y from imperfect data (discrete, truncated, censored).
method Optimal transformations to estimate p(y|x).
result Estimates location, scale, and shape of y distribution.
Applying machine learning in the health care domain has shown promising results in recent years. Interpretable outputs from learning algorithms are desirable for decision making by health care personnel. In this work, we explore the possibility of utilizing causal relationships to refine diagnostic prediction. We focus…
Establishes statistical and computational bounds for influence diagnostics.
problem Identifying influential datapoints or subsets in machine learning models.
method Finite-sample statistical bounds and computational complexity for influence functions and approximate maximum influence perturbations.
result Established statistical and computational guarantees for influence diagnostics.
The article explains how to estimate confusion matrices for classifiers using unlabeled data.
problem Estimating sensitivity and specificity of binary medical diagnostic tests without gold standard tests.
method Modifying diagnostic test solutions to estimate confusion matrices for classifiers on unlabeled data.
result The approach can be used to estimate accuracy statistics for supervised or unsupervised binary classifiers on unlabeled data.
We present Sequential Neural Likelihood (SNL), a new method for Bayesian inference in simulator models, where the likelihood is intractable but simulating data from the model is possible. SNL trains an autoregressive flow on simulated data in order to learn a model of the likelihood in the region of high posterior dens…
Paper evaluates whether AI is a bubble or a productivity revolution.
problem Determining if AI investments are a bubble or a sustainable technology.
method Hybrid review and diagnostic framework combining asset pricing foundations and modern econometric methods.
result AI investments show both genuine fundamentals and bubble-like fragilities.
AI enhances cancer diagnostics using spectroscopy.
problem Early and accurate cancer diagnosis.
method Combining AI with spectroscopy-based techniques.
result AI improves cancer diagnostics speed and safety.
Paper introduces a diagnostic for approximate inference methods.
problem Estimating errors in probabilistic inference algorithms, especially for approximate methods.
method Repeatedly simulate datasets from the prior and perform inference on each, estimating a symmetric KL-divergence.
result A diagnostic for approximate inference methods can be estimated using symmetric KL-divergence.
Machine learning improves diagnostic test accuracy for bovine tuberculosis.
problem Improving diagnostic test sensitivity for bovine tuberculosis.
method Machine learning to assess risk landscapes and predict infection.
result Test sensitivity improved, detecting 240 more infected herds per year.
A registration-free framework monitors shape and color in 4D point clouds.
problem Monitoring shape and color changes in complex parts without registration.
method Laplace-Beltrami operator spectral properties for geometric and color feature capture; combined monitoring scheme for shape and color anomalies.
result Effective detection of shape deformations and color anomalies without registration or mesh reconstruction.
Develops privacy-preserving methods for equivalence testing in healthcare.
problem Protecting patient data in healthcare studies.
method Differential privacy techniques for simulation-based calibration.
result Maintains type-I error control and comparable power to non-private methods.
Graph-based approach repairs programs from diagnostic feedback.
problem Learning to repair programs from limited labeled data and compiler error messages.
method Introduces program-feedback graph and graph neural network for reasoning, and self-supervised learning with unlabeled programs.
result DrRepair significantly outperforms prior work, achieving high repair rates.
Paper improves predictive distributions for rare events using a simple framework.
problem Local miscalibration of predictive distributions for rare events.
method Semiparametric diagnostic transport maps to correct tail probabilities.
result Semiparametric maps improve predictions for severe weather hazards.
TADDAA improves accuracy diagnostics for variational approximations.
problem Challenges in evaluating the accuracy of variational approximations.
method Uses many short parallel MCMC chains to obtain lower bounds on the error of each posterior functional of interest.
result Validates the practical utility and computational efficiency of TADDAA on various models.
Proposes a diagnostic method to evaluate factor models using cap-axis integrals.
problem Improving factor model evaluation in low-dimensional spaces.
method Lifts pricing errors into a bridge-alpha curve along the market-capitalization rank axis.
result The cap-axis norm is distinct from Sharpe gain and size exposure.
Proposes a diagnostic method to evaluate factor models using cap-axis integrals.
problem Improving factor model evaluation for low-dimensional models.
method Lifts pricing errors into a bridge-alpha curve along the market-capitalization rank axis.
result The cap-axis norm is distinct from Sharpe gain and size exposure.
The receiver operating characteristic (ROC) curve is a very useful tool for analyzing the diagnostic/classification power of instruments/classification schemes as long as a binary-scale gold standard is available. When the gold standard is continuous and there is no confirmative threshold, ROC curve becomes less useful…
We detect lookahead bias in LLM forecasts using a novel statistical method.
problem Detecting lookahead bias in LLM-generated economic forecasts.
method Developed a statistical procedure using date-only recall queries and estimated Lookahead Propensity (LAP).
result LLM forecasts are contaminated with lookahead bias, as indicated by a positive interaction between LAP and the forecast in accuracy regressions.
Language models fail to execute simple steps, showing gating and binding errors.
problem Procedural hallucinations in language models, failing to execute simple steps.
method Analyzed long-context binding tasks, identifying gating and binding errors.
result Procedural errors are due to gating and binding failures, with recency bias contributing to the latter.
The high-dimensionality and volume of large scale multistream data has inhibited significant research progress in developing an integrated monitoring and diagnostics (M&D) approach. This data, also categorized as big data, is becoming common in manufacturing plants. In this paper, we propose an integrated M\&D approach…
Language models fail to process hallucinated responses, and this study diagnoses the failure.
problem Language models fail to process hallucinated responses, leading to over-concentration or diffuse attention.
method The study uses forced scoring of benchmark-labeled responses to compute attention shapes and analyze the symmetric component of the degree-normalized attention operator.
result The study proves that every transpose-invariant spectral diagnostic of the attention operator is orientation-blind and bounds the sensitivity of any Lipschitz diagnostic by the asymmetry coefficient \(G\).
Diagnostic stroke imaging with C-arm cone-beam computed tomography (CBCT) enables reduction of time-to-therapy for endovascular procedures. However, the prolonged acquisition time compared to helical CT increases the likelihood of rigid patient motion. Rigid motion corrupts the geometry alignment assumed during reconst…
Recent studies have shown promising results in using Deep Learning to detect malignancy in whole slide imaging. However, they were limited to just predicting positive or negative finding for a specific neoplasm. We attempted to use Deep Learning with a convolutional neural network algorithm to build a lymphoma diagnost…
Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational formulation of black-box interpretation, general interpretability research rely hea…
Online symptom checkers have significant potential to improve patient care, however their reliability and accuracy remain variable. We hypothesised that an artificial intelligence (AI) powered triage and diagnostic system would compare favourably with human doctors with respect to triage and diagnostic accuracy. We per…
Reducing ICD-10 code granularity improves cost model accuracy and stability.
problem High-dimensional regression with ICD-10 codes leads to unstable coefficient estimates.
method Log-linear analytics approach to cost model regularization through diagnostic code merging.
result Reducing ICD-10 code granularity from 7 characters to 6 or fewer improves model interpretability and consistency.
The paper introduces diagnostic transport maps to improve the reliability of rare event predictions.
problem Improper calibration of predictive distributions, especially for rare events.
method Diagnostic transport maps to adjust base model's probabilities for better calibration.
result Diagnostic transport maps improve predictive performance for rare events, including 24-hour rapid intensity change.
Develops a diagnostic framework for interest rate model calibration, showing equivalence to Weighted Least Squares and revealing boundary-dominated leverage and local parameter instability.
problem Calibration of stochastic interest rate models
method Diagnostic framework using non-linear regression and analytical tractability of At-The-Money caps
result Reveals boundary-dominated leverage and local parameter instability
The paper breaks down AUC into cluster-level components for better model diagnostics.
problem Global AUC masks weaknesses in specific subpopulations, leading to financial or operational risks.
method Formal decomposition of AUC into intra- and inter-cluster components, comparing with other performance metrics.
result Allows practitioners to evaluate and diagnose model performance within and across clusters.
According to the Loss Distribution Approach, the operational risk of a bank is determined as 99.9% quantile of the respective loss distribution, covering unexpected severe events. The 99.9% quantile can be considered a tail event. As supported by the Pickands-Balkema-de Haan Theorem, tail events exceeding some high thr…
Generative models often fail to preserve joint structure despite matching marginals.
problem Generative models fail to capture complex dependencies beyond univariate marginals.
method Introduced D_Sigma(P,Q) = ||Sigma_P - Sigma_Q||_F to measure covariance-level dependence fidelity.
result Covariance-level divergence can lead to structural instability in downstream inference.
Proposes FACT, a diagnostic for understanding group fairness trade-offs.
problem Group fairness notions often conflict with each other, requiring a cost in model performance.
method Characterizes trade-offs via the fairness-confusion tensor and optimizes accuracy and fairness objectives.
result Demonstrates the use of FACT on synthetic and real datasets to understand accuracy-fairness trade-offs.
This paper simplifies deep ReLU networks into local linear models for better interpretability.
problem Limited transparency and interpretability of deep neural networks, especially ReLU networks.
method Local linear representation and equivalent set of local linear models (LLMs).
result Simplified deep ReLU networks for better interpretability and diagnostics.
A new HP model balances interpretability and flexibility for EHR event sequences.
problem Balancing interpretability and flexibility in modeling diagnostic event sequences.
method Proposes a neural network-based HP with flexible impact kernel and transformer layers.
result Accurately recovers impact functions, competitive performance, and clinically meaningful interpretation.