Applying machine learning in the health care domain has shown promising results in recent years. Interpretable outputs from learning algorithms are desirable for decision making by health care personnel. In this work, we explore the possibility of utilizing causal relationships to refine diagnostic prediction. We focus…
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48 results for “diagnostic labels”
Improves reliability of medical diagnosis uncertainty estimates.
problem Label uncertainty in medical diagnosis.
method Post-hoc -calibration method for neural network classifiers.
result Significantly enhances reliability of uncertainty estimates.
Supervised topic models can help clinical researchers find interpretable cooccurence patterns in count data that are relevant for diagnostics. However, standard formulations of supervised Latent Dirichlet Allocation have two problems. First, when documents have many more words than labels, the influence of the labels w…
Paper tackles gene mutation prediction for HCC using multi-instance multi-label learning.
problem Gene mutation prediction in hepatocellular carcinoma for personalized treatments.
method Multi-instance multi-label learning with oversampling for data imbalance.
result Proposed approach shows superiority in gene mutation prediction.
Graph-based approach repairs programs from diagnostic feedback.
problem Learning to repair programs from limited labeled data and compiler error messages.
method Introduces program-feedback graph and graph neural network for reasoning, and self-supervised learning with unlabeled programs.
result DrRepair significantly outperforms prior work, achieving high repair rates.
Deep chest X-ray classifiers show bias in predicting diagnoses.
problem Bias in deep learning classifiers predicting diagnoses from chest X-rays.
method Trained convolutional neural networks on multiple public datasets to predict 14 diagnostic labels.
result True positive rates vary significantly among different protected attributes, indicating bias.
GCNs help in diagnosing label scarcity and feature quality on graphs.
problem Understanding when GCNs improve node classification.
method Simulated label scarcity, feature ablation, and per-class analysis.
result GCNs provide largest gains under extreme label scarcity, matching original performance with noisy features, but hurt when homophily is low and features are strong.
New framework uses geometry of embeddings to predict robustness.
problem Monitoring robustness in models without OOD labels.
method Constructs graphs from embeddings, measures spectral complexity and curvature.
result Representation geometry predicts robustness reliably.
When to Trust Confidence Thresholding: Calibration Diagnostics for Pseudo-Labelled Regressionstat.ME
The study examines when to trust confidence thresholding in pseudo-labelling regression.
problem Calibrated probabilities from classifiers used for pseudo-labelling need careful handling to avoid bias in downstream regression.
method Developed a diagnostic apparatus to predict and bound the bias induced by confidence thresholding, derived a closed-form expression for the attenuation bias.
result The bias can be predicted from the residual score variance , motivating a structural separation between classifier features and downstream controls.
Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in practice: 1) only limited labeled samples are available due to expensive annotation costs over medical images; 2) labeled images may contain considerable label noises (e.g., mi…
Data-driven fault diagnostics of safety-critical systems often faces the challenge of a complete lack of labeled data associated with faulty system conditions (i.e., fault types) at training time. Since an unknown number and nature of fault types can arise during deployment, data-driven fault diagnostics in this scenar…
Language models fail to process hallucinated responses, and this study diagnoses the failure.
problem Language models fail to process hallucinated responses, leading to over-concentration or diffuse attention.
method The study uses forced scoring of benchmark-labeled responses to compute attention shapes and analyze the symmetric component of the degree-normalized attention operator.
result The study proves that every transpose-invariant spectral diagnostic of the attention operator is orientation-blind and bounds the sensitivity of any Lipschitz diagnostic by the asymmetry coefficient \(G\).
Paper presents a probabilistic diagnostic model for identifying and treating supervised learning degradation issues.
problem Degradation problems in supervised learning, including class imbalance, overlapping, small-disjuncts, noisy labels, and sparseness.
method Develops a novel probabilistic diagnostic model to identify and treat degradation issues in supervised learning.
result Early and correct diagnosis of degradation issues allows for selecting appropriate remediation treatments and unbiased performance metrics.
DCEM algorithm reduces bias in machine learning models trained on selective labels.
problem Bias in machine learning models trained on selective labels.
method Disparate Censorship Expectation-Maximization (DCEM) algorithm.
result DCEM improves bias mitigation without sacrificing discriminative performance.
Quickly adapts fault diagnosis models for industrial machines.
problem Fault diagnostic models trained for lab machines fail on industrial ones.
method Net2Net transformation followed by fine-tuning.
result Models can be quickly adapted for new operating conditions.
Cost-efficient feature selection for multi-label classification in medicine.
problem Feature selection in multi-label classification with cost constraints.
method Sequential feature selection maximizing conditional mutual information, followed by cost-free feature selection using shadow features.
result The method effectively reduces prediction costs in medical applications.
This paper refines human labeling as a measurement process, revealing four sources of variation.
problem Systematic variation in human labeling obscures model learning.
method Introduces a statistical framework to decompose labeling outcomes.
result Empirical evidence for four components of labeling variation.
Discriminative neural networks address class imbalance in coronary heart disease risk analysis.
problem Class imbalance in medical test data, especially in binary classification problems.
method Use of discriminative neural networks and contrastive loss with a Siamese network structure.
result The method effectively handles class imbalance, improving predictive models for coronary heart disease risk.
Unified framework explains few-shot multimodal medical imaging performance.
problem Limited labeled data in rare diseases and low-resource settings.
method PAC learning, VC theory, PAC Bayesian analysis, information gain, Chain of Thought reasoning.
result Unified theoretical framework for few-shot multimodal medical imaging.
Analysis of Diagnostics (Part I): Prevalence, Uncertainty Quantification, and Machine Learningstat.ML
This study connects prevalence and machine learning for diagnostic testing.
problem Uncertainty quantification in machine learning for diagnostic tests.
method Developed a numerical homotopy algorithm to estimate classification boundaries and quantify uncertainty.
result The proposed method stabilizes uncertainty quantification in machine learning for diagnostic tests.
Melanoma is the deadliest form of skin cancer. Computer systems can assist in melanoma detection, but are not widespread in clinical practice. In 2016, an open challenge in classification of dermoscopic images of skin lesions was announced. A training set of 900 images with corresponding class labels and semi-automatic…
This paper revisits the problem of analyzing multiple ratings given by different judges. Different from previous work that focuses on distilling the true labels from noisy crowdsourcing ratings, we emphasize gaining diagnostic insights into our in-house well-trained judges. We generalize the well-known DawidSkene model…
DECAT framework evaluates multimodal models for shared biology, detecting confounders and false positives.
problem Determining if multimodal models learn shared biology or just confounders.
method DECAT framework classifies multimodal representations into four diagnostic scenarios using null-referenced metrics.
result DECAT detects confounders and false positives in multimodal models, improving with larger cohorts and stronger representations.
Establishes statistical and computational bounds for influence diagnostics.
problem Identifying influential datapoints or subsets in machine learning models.
method Finite-sample statistical bounds and computational complexity for influence functions and approximate maximum influence perturbations.
result Established statistical and computational guarantees for influence diagnostics.
The article explains how to estimate confusion matrices for classifiers using unlabeled data.
problem Estimating sensitivity and specificity of binary medical diagnostic tests without gold standard tests.
method Modifying diagnostic test solutions to estimate confusion matrices for classifiers on unlabeled data.
result The approach can be used to estimate accuracy statistics for supervised or unsupervised binary classifiers on unlabeled data.
Lung cancer is the leading cause of cancer-related death worldwide. Early diagnosis of pulmonary nodules in Computed Tomography (CT) chest scans provides an opportunity for designing effective treatment and making financial and care plans. In this paper, we consider the problem of diagnostic classification between beni…
PPI uses predictions to improve inference from incomplete data.
problem Incomplete or costly-to-measure outcomes in research fields.
method Leverages large unlabeled datasets for improved statistical efficiency with bias correction.
result PPI variants produce tighter confidence intervals than complete-case analysis.
Improves disease progression prediction using auxiliary surrogate labels and health markers.
problem Challenges in predicting disease progression due to unknown true disease states.
method Integrates hidden Markov model with time-varying discriminative classification model.
result Significant improvement in distinguishing LBD from AD using objective markers.
CheXpert++: Approximating the CheXpert labeler for Speed,Differentiability, and Probabilistic Outputcs.LG
CheXpert++ improves CheXpert's accuracy and usability for medical radiology reports.
problem Infeasibility of obtaining ground truth labels for medical data.
method BERT-based approximation of CheXpert, addressing speed, differentiability, and probabilistic output.
result Achieves 99.81% parity with CheXpert, significantly faster, differentiable, and probabilistic.
We propose a method for generating an electrocardiogram (ECG) signal for one cardiac cycle using a variational autoencoder. Using this method we extracted a vector of new 25 features, which in many cases can be interpreted. The generated ECG has quite natural appearance. The low value of the Maximum Mean Discrepancy me…
AI enhances cancer diagnostics using spectroscopy.
problem Early and accurate cancer diagnosis.
method Combining AI with spectroscopy-based techniques.
result AI improves cancer diagnostics speed and safety.
An Easy to Interpret Diagnostic for Approximate Inference: Symmetric Divergence Over Simulationscs.LG
Paper introduces a diagnostic for approximate inference methods.
problem Estimating errors in probabilistic inference algorithms, especially for approximate methods.
method Repeatedly simulate datasets from the prior and perform inference on each, estimating a symmetric KL-divergence.
result A diagnostic for approximate inference methods can be estimated using symmetric KL-divergence.
Machine learning augmented diagnostic testing to identify sources of variability in test performancecs.LG
Machine learning improves diagnostic test accuracy for bovine tuberculosis.
problem Improving diagnostic test sensitivity for bovine tuberculosis.
method Machine learning to assess risk landscapes and predict infection.
result Test sensitivity improved, detecting 240 more infected herds per year.
AI predicts medical specialty diagnostic choices from EHR records.
problem Predicting timely medical specialty diagnostic workups for patients.
method Ensemble of feed-forward neural networks trained on EHR data.
result Significantly higher accuracy compared to traditional checklists.
TRACE analyzes risk changes in models trained on shifted data.
problem Understanding performance changes when a model trained on shifted data is used.
method TRACE framework decomposes risk change into four factors: generalization gaps, model change penalty, and covariate shift penalty.
result TRACE provides a diagnostic tool to understand and quantify risk changes due to covariate shift.
Bayesian analysis reveals epistemic uncertainty as a key diagnostic for delayed generalization in in-context learning.
problem Delayed generalization in in-context learning from few examples.
method Bayesian perspective, modular arithmetic tasks, approximate Bayesian techniques, spectral mechanism analysis.
result Epistemic uncertainty collapses sharply when the model groks, indicating a practical diagnostic of generalization.
This paper presents a novel approach for detection of liver abnormalities in an automated manner using ultrasound images. For this purpose, we have implemented a machine learning model that can not only generate labels (normal and abnormal) for a given ultrasound image but it can also detect when its prediction is like…
Machine learning improves EEG pathology classification.
problem Automating clinical EEG analysis using machine learning.
method Developed a comprehensive feature-based framework and compared it to deep neural networks.
result Feature-based framework achieves accuracies similar to deep neural networks.
GraphXCOVID uses deep semi-supervised learning to identify COVID-19 from chest X-rays with minimal labels.
problem Identifying COVID-19 on chest X-rays with limited labelled data.
method Graph-based deep semi-supervised framework with pseudo-labeling and attention maps.
result Outperforms current supervised models with a tiny fraction of labelled examples.
Deployment of machine learning (ML) algorithms in production for extended periods of time has uncovered new challenges such as monitoring and management of real-time prediction quality of a model in the absence of labels. However, such tracking is imperative to prevent catastrophic business outcomes resulting from inco…
The paper analyzes convergence in SGD with momentum and proposes a diagnostic test.
problem Detecting convergence in stochastic gradient descent with momentum.
method Analyzes the transient and stationary phases of SGD with momentum, constructs a statistical diagnostic test.
result The proposed diagnostic test effectively detects convergence in the stationary phase of SGD with momentum.
In this paper, we propose a new metric to measure goodness-of-fit for classifiers, the Real World Cost function. This metric factors in information about a real world problem, such as financial impact, that other measures like accuracy or F1 do not. This metric is also more directly interpretable for users. To optimize…
Paper proposes a coupling-based diagnostic for SGD stepsize optimization.
problem Optimizing stepsize for SGD convergence.
method Coupling-based convergence diagnostic for monitoring stationarity.
result Proposed stepsize scheme achieves superior performance across convex and non-convex problems.
Trustworthy Predictive Distributions for Tail Events with Semiparametric Diagnostic Transport Mapsstat.ML
Paper improves predictive distributions for rare events using a simple framework.
problem Local miscalibration of predictive distributions for rare events.
method Semiparametric diagnostic transport maps to correct tail probabilities.
result Semiparametric maps improve predictions for severe weather hazards.
TADDAA improves accuracy diagnostics for variational approximations.
problem Challenges in evaluating the accuracy of variational approximations.
method Uses many short parallel MCMC chains to obtain lower bounds on the error of each posterior functional of interest.
result Validates the practical utility and computational efficiency of TADDAA on various models.
Proposes a diagnostic method to evaluate factor models using cap-axis integrals.
problem Improving factor model evaluation in low-dimensional spaces.
method Lifts pricing errors into a bridge-alpha curve along the market-capitalization rank axis.
result The cap-axis norm is distinct from Sharpe gain and size exposure.
Proposes a diagnostic method to evaluate factor models using cap-axis integrals.
problem Improving factor model evaluation for low-dimensional models.
method Lifts pricing errors into a bridge-alpha curve along the market-capitalization rank axis.
result The cap-axis norm is distinct from Sharpe gain and size exposure.
The receiver operating characteristic (ROC) curve is a very useful tool for analyzing the diagnostic/classification power of instruments/classification schemes as long as a binary-scale gold standard is available. When the gold standard is continuous and there is no confirmative threshold, ROC curve becomes less useful…