MSBM extends SB for multi-marginal trajectory inference.
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Preschool attendance correlates with lower developmental vulnerabilities in Queensland, Australia.
We compare the acquisition of knowledge in humans and machines. Research from the field of developmental psychology indicates, that human-employed hypothesis are initially guided by simple rules, before evolving into more complex theories. This observation is shared across many tasks and domains. We investigate whether…
Infants with a variety of complications at or before birth are classified as being at risk for developmental delays (AR). As they grow older, they are followed by healthcare providers in an effort to discern whether they are on a typical or impaired developmental trajectory. Often, it is difficult to make an accurate d…
NESS improves neighbor embedding for smooth cell-state transitions in single-cell data.
Robots learn actions and language through curiosity-driven self-exploration.
There is a growing need for fast and accurate methods for testing developmental neurotoxicity across several chemical exposure sources. Current approaches, such as in vivo animal studies, and assays of animal and human primary cell cultures, suffer from challenges related to time, cost, and applicability to human physi…
Sensorimotor contingency theory offers a promising account of the nature of perception, a topic rarely addressed in the robotics community. We propose a developmental framework to address the problem of the autonomous acquisition of sensorimotor contingencies by a naive robot. While exploring the world, the robot inter…
A new framework ensures model safety by retaining old model capabilities while improving new tasks.
A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine designed for relating a researcher's experimental dataset to earlier work in the …
Benchmark tests spoken language models for infant language learning.
USD algorithm transports distributions with or without mass conservation.
Human brain development is rapid during infancy and early childhood. Many disease processes impair this development. Therefore, brain developmental age estimation (BDAE) is essential for all diseases affecting cognitive development. Brain magnetic resonance imaging (MRI) of infants shows brain growth and morphologic pa…
DECAT framework evaluates multimodal models for shared biology, detecting confounders and false positives.
Biology has changed radically in the last two decades, transitioning from a descriptive science into a design science. Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules such as renewable biofuels or anticancer drugs. However, traditional synthetic biology approaches involve ad-hoc …
Optimal algorithm selects biological models without prior info.
Two simulation-based methods improve optimal sampling design in systems biology.
Developmental Dyslexia (DD) is a learning disability related to the acquisition of reading skills that affects about 5% of the population. DD can have an enormous impact on the intellectual and personal development of affected children, so early detection is key to implementing preventive strategies for teaching langua…
Unified framework for Schrödinger Bridge solutions between arbitrary densities.
Quantum computing promises faster bioinformatics, but challenges remain.
A scalable Bayesian inference method for mixed-effects models in systems biology.
ProGen models protein sequences for synthetic biology.
Method uses network biology to construct gene expression models for cancer.
Innovation is among the key factors driving a country's economic and social growth. But what are the factors that make a country innovative? How do they differ across different parts of the world and different stages of development? In this work done in collaboration with the World Economic Forum (WEF), we analyze the …
The paper uses distance correlation for brain connectivity and a novel multi-task learning model for age prediction.
In this paper, we provide conditions which ensure that stochastic Lipschitz BSDEs admit Malliavin differentiable solutions. We investigate the problem of existence of densities for the first components of solutions to general path-dependent stochastic Lipschitz BSDEs and obtain results for the second components in part…
The study explores how brain development can inspire efficient deep learning models.
BiLiNGAM model reveals brain emotion circuit development in adolescents.
nUDEs use neural networks to model biology without negative values.
New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome, phenotype, and lifestyle. No single data type, however, can capture the complexity of…
hyperSBINN improves drug cardiosafety assessment by efficiently modeling cardiac action potentials.
Network models have been popular for modeling and representing complex relationships and dependencies between observed variables. When data comes from a dynamic stochastic process, a single static network model cannot adequately capture transient dependencies, such as, gene regulatory dependencies throughout a developm…
We consider the problem of joint modelling of metabolic signals and gene expression in systems biology applications. We propose an approach based on input-output factorial hidden Markov models and propose a structured variational inference approach to infer the structure and states of the model. We start from the class…
X-SHAP assesses multiplicative variable contributions in machine learning models.
Developmental Robotics offers a new approach to numerous AI features that are often taken as granted. Traditionally, perception is supposed to be an inherent capacity of the agent. Moreover, it largely relies on models built by the system's designer. A new approach is to consider perception as an experimentally acquire…
BioBO optimizes gene perturbation design using Bayesian optimization with biological priors.
This research investigates the Statistical Machine Translation approaches to translate speech in real time automatically. Such systems can be used in a pipeline with speech recognition and synthesis software in order to produce a real-time voice communication system between foreigners. We obtained three main data sets …
Autonomous multiple tasks learning is a fundamental capability to develop versatile artificial agents that can act in complex environments. In real-world scenarios, tasks may be interrelated (or "hierarchical") so that a robot has to first learn to achieve some of them to set the preconditions for learning other ones. …
Geometric modeling for human food and chemical sensitivities.
New algorithm optimizes matrix reordering for noisy disordered matrices.
Preterm newborns undergo various stresses that may materialize as learning problems at school-age. Sleep staging of the Electroencephalogram (EEG), followed by prediction of their brain-age from these sleep states can quantify deviations from normal brain development early (when compared to the known age). Current auto…
Preterm births occur at an alarming rate of 10-15%. Preemies have a higher risk of infant mortality, developmental retardation and long-term disabilities. Predicting preterm birth is difficult, even for the most experienced clinicians. The most well-designed clinical study thus far reaches a modest sensitivity of 18.2-…
DAG-FOCI learns causal relationships without parametric assumptions.
COMRECGC finds common recourse for global counterfactual explanations in GNNs.
Physics analogies explain machine learning overfitting control.
We consider continuous time Markovian processes where populations of individual agents interact stochastically according to kinetic rules. Despite the increasing prominence of such models in fields ranging from biology to smart cities, Bayesian inference for such systems remains challenging, as these are continuous tim…
It has been suggested in developmental psychology literature that the communication of affect between mothers and their infants correlates with the socioemotional and cognitive development of infants. In this study, we obtained day-long audio recordings of 10 mother-infant pairs in order to study their affect communica…
We address the problem of parameter estimation in models of systems biology from noisy observations. The models we consider are characterized by simultaneous deterministic nonlinear differential equations whose parameters are either taken from in vitro experiments, or are hand-tuned during the model development process…