Framework improves clinical timeline reconstruction from text and tables.
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Machine learning predicts patient recruitment for clinical trials.
Study examines APOE's impact on AD progression using a novel DEBM approach.
Heart failure (HF) is one of the leading causes of hospital admissions in the US. Readmission within 30 days after a HF hospitalization is both a recognized indicator for disease progression and a source of considerable financial burden to the healthcare system. Consequently, the identification of patients at risk for …
Study a simplified model of multiverse structure with synchronized timelines.
Twitter releases dataset to study user engagement on Home Timeline, focusing on privacy.
Alzheimer's Disease (AD) is characterized by a cascade of biomarkers becoming abnormal, the pathophysiology of which is very complex and largely unknown. Event-based modeling (EBM) is a data-driven technique to estimate the sequence in which biomarkers for a disease become abnormal based on cross-sectional data. It can…
Much recent research aims to identify evidence for Drug-Drug Interactions (DDI) and Adverse Drug reactions (ADR) from the biomedical scientific literature. In addition to this "Bibliome", the universe of social media provides a very promising source of large-scale data that can help identify DDI and ADR in ways that ha…
The current work characterizes the users of a VoD streaming space through user-personas based on a tenure timeline and temporal behavioral features in the absence of explicit user profiles. A combination of tenure timeline and temporal characteristics caters to business needs of understanding the evolution and phases o…
Two new estimators reduce costs and improve accuracy for EHR outcome prediction.
Network medicine predicts repurposable drugs for COVID-19.
This report reviews the Edinburgh tram project's risk management. Projects frequently overrun their cost and timelines and fall short on intended benefits. Cost, schedule, and benefit risk of projects need to be carefully considered to avoid this. The report describes and evaluates risk assessment and management for th…
The paper introduces SuccessProbaMax to optimize policy success probability in online advertising.
This study improves stock price forecasting by analyzing daily news sentiment.
Wastewater infrastructure systems deteriorate over time due to a combination of physical and chemical factors. Failure of this significant infrastructure could affect important social, environmental, and economic impacts. Furthermore, recognizing the optimized timeline for inspection of sewer pipelines are challenging …
Develops platforms to analyze social media data for human behavior and emotions.
The paper predicts diseases using both clinical and genomics data.
Determinantal point processes (DPPs) are elegant probabilistic models of repulsion that arise in quantum physics and random matrix theory. In contrast to traditional structured models like Markov random fields, which become intractable and hard to approximate in the presence of negative correlations, DPPs offer efficie…
Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep learning models for the prediction of clinical outcomes using clinical notes. Ho…
Clinical AI models fail to transfer between sites due to site-specific practices.
System suggests clinical concepts in real-time for faster note creation.
We introduce SparseVM, a method that registers clinical-quality 3D MR scans both faster and more accurately than previously possible. Deformable alignment, or registration, of clinical scans is a fundamental task for many clinical neuroscience studies. However, most registration algorithms are designed for high-resolut…
AI predicts medical specialty diagnostic choices from EHR records.
Novel metrics improve machine learning models for ICU patient care.
Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand irregular clinical event sequences. We make the observation that clinical events at a…
With the maturation of metabolomics science and proliferation of biobanks, clinical metabolic profiling is an increasingly opportunistic frontier for advancing translational clinical research. Automated Machine Learning (AutoML) approaches provide exciting opportunity to guide feature selection in agnostic metabolic pr…
Skin cancer is one of the most common types of cancer around the world. For this reason, over the past years, different approaches have been proposed to assist detect it. Nonetheless, most of them are based only on dermoscopy images and do not take into account the patient clinical information. In this work, first, we …
Study develops a new algorithm for assessing clinical trial abstracts.
Improved negation detection in Dutch clinical texts using machine learning.
The paper explores using historical data to improve clinical trial analysis by optimizing covariate weights.
Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression rate, impairment of memory and cognitive abilities. Due to these variabilities, …
Study examines biases in clinical word embeddings, revealing performance gaps across groups.
Study improves healthcare time series imputation by considering structured missingness.
New method detects biomarker-treatment interactions in clinical trials.
In this chapter, we provide a brief overview of applying machine learning techniques for clinical prediction tasks. We begin with a quick introduction to the concepts of machine learning and outline some of the most common machine learning algorithms. Next, we demonstrate how to apply the algorithms with appropriate to…
Improved language model for French clinical reports achieves state-of-the-art performance in medical NLP tasks.
The recent adoption of Electronic Health Records (EHRs) by health care providers has introduced an important source of data that provides detailed and highly specific insights into patient phenotypes over large cohorts. These datasets, in combination with machine learning and statistical approaches, generate new opport…
Late fusion of clinical notes and physiological data improves ICU mortality prediction.
Deep learning analyzes healthcare provider actions and patient outcomes.
Discusses handling intercurrent events in clinical trials with time-to-event outcomes.
Clinical forecasting based on electronic medical records (EMR) can uncover the temporal correlations between patients' conditions and outcomes from sequences of longitudinal clinical measurements. In this work, we propose an intervention-augmented deep state space generative model to capture the interactions among clin…
Machine learning is bringing a paradigm shift to healthcare by changing the process of disease diagnosis and prognosis in clinics and hospitals. This development equips doctors and medical staff with tools to evaluate their hypotheses and hence make more precise decisions. Although most current research in the literatu…
Unified model combines neural networks and dictionary learning for clinical predictions from brain data.
Current clinical practice to monitor patients' health follows either regular or heuristic-based lab test (e.g. blood test) scheduling. Such practice not only gives rise to redundant measurements accruing cost, but may even lead to unnecessary patient discomfort. From the computational perspective, heuristic-based test …
Clinical notes are a rich source of information about patient state. However, using them to predict clinical events with machine learning models is challenging. They are very high dimensional, sparse and have complex structure. Furthermore, training data is often scarce because it is expensive to obtain reliable labels…
CoI framework models clinical feature interactions, revealing temporal dependencies and enhancing transparency.
Method predicts biomarker trajectories with uncertainty bands for Alzheimer's disease.
RL improves combinatorial optimization by automating heuristic search.