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0111 · Sep 201319922001200920172026
7 results for APOE

The OSCAR (octagonal selection and clustering algorithm for regression) regularizer consists of a L_1 norm plus a pair-wise L_inf norm (responsible for its grouping behavior) and was proposed to encourage group sparsity in scenarios where the groups are a priori unknown. The OSCAR regularizer has a non-trivial proximit…

2013-09-24abs ↗pdf ↗

Study examines APOE's impact on AD progression using a novel DEBM approach.

problem Understanding APOE's role in AD progression and developing targeted clinical trials.
method Developed a discriminative event-based model (DEBM) and proposed a stratified approach to improve model accuracy.
result Identified APOE carriers' impact on AD progression timeline, aiding clinical trial selection.

APo-VAE generates text in hyperbolic space for better hierarchical representation.

problem Lack of hierarchical structure in Euclidean embeddings for natural language.
method Adversarial Poincare Variational Autoencoder (APo-VAE) in hyperbolic latent space.
result APo-VAE outperforms Euclidean VAEs in capturing latent language hierarchies.

Novel method identifies proteomic risk markers for Alzheimer disease.

problem Lack of comprehensive proteomic risk markers for Alzheimer disease diagnosis.
method Deep belief network-based feature selection method using proteomic and clinical data.
result Identified an optimal subset of proteins achieving 90% accuracy in Alzheimer disease diagnosis.