Unified model combines neural networks and dictionary learning for clinical predictions from brain data.
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Framework predicts clinical severity from rs-fMRI data using network optimization.
Pairwise ranking aligns subjective clinical evaluations with objective indicators.
Clinical forecasting based on electronic medical records (EMR) can uncover the temporal correlations between patients' conditions and outcomes from sequences of longitudinal clinical measurements. In this work, we propose an intervention-augmented deep state space generative model to capture the interactions among clin…
Predictive models identify patients at risk of severe COVID-19.
Study develops models to predict severe COVID-19 progression.
The recent adoption of Electronic Health Records (EHRs) by health care providers has introduced an important source of data that provides detailed and highly specific insights into patient phenotypes over large cohorts. These datasets, in combination with machine learning and statistical approaches, generate new opport…
In healthcare, patient risk stratification models are often learned using time-series data extracted from electronic health records. When extracting data for a clinical prediction task, several formulations exist, depending on how one chooses the time of prediction and the prediction horizon. In this paper, we show how…
Machine learning is bringing a paradigm shift to healthcare by changing the process of disease diagnosis and prognosis in clinics and hospitals. This development equips doctors and medical staff with tools to evaluate their hypotheses and hence make more precise decisions. Although most current research in the literatu…
This paper aims to evaluate the suitability of current deep learning methods for clinical workflow especially by focusing on dermatology. Although deep learning methods have been attempted to get dermatologist level accuracy in several individual conditions, it has not been rigorously tested for common clinical complai…
The problem of missing values in multivariable time series is a key challenge in many applications such as clinical data mining. Although many imputation methods show their effectiveness in many applications, few of them are designed to accommodate clinical multivariable time series. In this work, we propose a multiple…
Enhances generative model for clinical data privacy and accuracy.
New method targets relative risk heterogeneity in clinical trials.
Scalable methods integrate multiview data for clinical outcomes.
We develop a multi-task convolutional neural network (CNN) to classify multiple diagnoses from 12-lead electrocardiograms (ECGs) using a dataset comprised of over 40,000 ECGs, with labels derived from cardiologist clinical interpretations. Since many clinically important classes can occur in low frequencies, approaches…
System predicts respiratory failure up to 8 hours early.
Sepsis is the leading cause of death in non-coronary intensive care units. Moreover, a delay of antibiotic treatment of patients with severe sepsis by only few hours is associated with increased mortality. This insight makes accurate models for early prediction of sepsis a key task in machine learning for healthcare. P…
Copula-based fusion improves breast cancer risk stratification.
Study predicts antimicrobial resistance in ICU patients quickly.
Heart failure hospitalization is a severe burden on healthcare. How to predict and therefore prevent readmission has been a significant challenge in outcomes research. To address this, we propose a deep learning approach to predict readmission from clinical notes. Unlike conventional methods that use structured data fo…
Deep learning-based health status representation learning and clinical prediction have raised much research interest in recent years. Existing models have shown superior performance, but there are still several major issues that have not been fully taken into consideration. First, the historical variation pattern of th…
FRESH combines patient-level and aggregate-level data for better clinical decision making.
Study examines impact of fairness penalties on clinical risk prediction models.
Method augments CTNs for ICD coding with neural network imputation.
Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may be high, but the model still consistently misses a rare but aggressive cancer su…
Deep neural networks have shown promising results for various clinical prediction tasks such as diagnosis, mortality prediction, predicting duration of stay in hospital, etc. However, training deep networks -- such as those based on Recurrent Neural Networks (RNNs) -- requires large labeled data, high computational res…
With widespread adoption of electronic health records, there is an increased emphasis for predictive models that can effectively deal with clinical time-series data. Powered by Recurrent Neural Network (RNN) architectures with Long Short-Term Memory (LSTM) units, deep neural networks have achieved state-of-the-art resu…
Machine learning (ML) is increasingly used to support decision-making in the healthcare sector. While ML approaches provide promising results with regard to their classification performance, most share a central limitation, namely their black-box character. Motivated by the interest to understand the functioning of ML …
The paper proposes a method to predict the performance of data-driven algorithms using surrogate models.
In this work we explored building automatic speech recognition models for transcribing doctor patient conversation. We collected a large scale dataset of clinical conversations ( hr), designed the task to represent the real word scenario, and explored several alignment approaches to iteratively improve data qua…
Framework integrates brain connectivity data for clinical predictions.
This paper considers the problems of modeling and predicting a long-term and ``blurry'' relapse that occurs after a medical act, such as a surgery. The relapse is observed only indirectly, in a ``blurry'' fashion, through longitudinal prescriptions of drugs over a long period of time after the medical act. We introduce…
Determining the optimal initial dose for warfarin is a critically important task. Several factors have an impact on the therapeutic dose for individual patients, such as patients' physical attributes (Age, Height, etc.), medication profile, co-morbidities, and metabolic genotypes (CYP2C9 and VKORC1). These wide range f…
In this work, we consider the problem of predicting the course of a progressive disease, such as cancer or Alzheimer's. Progressive diseases often start with mild symptoms that might precede a diagnosis, and each patient follows their own trajectory. Patient trajectories exhibit wild variability, which can be associate…
DDGM generates realistic ECG signals for clinical use.
Deep learning models (aka Deep Neural Networks) have revolutionized many fields including computer vision, natural language processing, speech recognition, and is being increasingly used in clinical healthcare applications. However, few works exist which have benchmarked the performance of the deep learning models with…
The paper predicts diseases using both clinical and genomics data.
Transformers improve Alzheimer's disease progression prediction by accounting for irregular biomarker histories.
Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep learning models for the prediction of clinical outcomes using clinical notes. Ho…
Deep IDA integrates multi-view data to classify COVID-19 severity, identifying molecular signatures.
Hybrid Bayesian-conformal framework improves uncertainty quantification in healthcare predictions.
Large vessel occlusion (LVO) plays an important role in the diagnosis of acute ischemic stroke. Identifying LVO of patients in the early stage on admission would significantly lower the probabilities of suffering from severe effects due to stroke or even save their lives. In this paper, we utilized both structural and …
Teaches reproducible research to medical students and postgrads.
Deep learning with medical data often requires larger samples sizes than are available at single providers. While data sharing among institutions is desirable to train more accurate and sophisticated models, it can lead to severe privacy concerns due the sensitive nature of the data. This problem has motivated a number…
Clinical AI models fail to transfer between sites due to site-specific practices.
Bipolar disorder (BPD) is a chronic mental illness characterized by extreme mood and energy changes from mania to depression. These changes drive behaviors that often lead to devastating personal or social consequences. BPD is managed clinically with regular interactions with care providers, who assess mood, energy lev…
System suggests clinical concepts in real-time for faster note creation.
Deep learning model creates patient representations for scalable EHR-based stratification.