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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,695 papers · 148 categories

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48 results for clinical severity

Unified model combines neural networks and dictionary learning for clinical predictions from brain data.

problem Predicting clinical severity from brain imaging data.
method Combines neural networks with dictionary learning to model patient-specific and shared features.
result Unified model outperforms state-of-the-art methods in predicting clinical severity.

Framework predicts clinical severity from rs-fMRI data using network optimization.

problem Predicting clinical severity from rs-fMRI data.
method Joint network optimization framework combining sparse subnetworks and linear regression.
result Framework outperforms standard methods and identifies clinically relevant ASD networks.

Pairwise ranking aligns subjective clinical evaluations with objective indicators.

problem Aligning subjective clinical evaluations with objective indicators for improved diagnosis.
method Pairwise ranking methods to align subjective evaluations with objective indicators.
result The resulting score improves classification accuracy and provides a nuanced severity assessment.

Clinical forecasting based on electronic medical records (EMR) can uncover the temporal correlations between patients' conditions and outcomes from sequences of longitudinal clinical measurements. In this work, we propose an intervention-augmented deep state space generative model to capture the interactions among clin…

2019-12-04abs ↗pdf ↗

In healthcare, patient risk stratification models are often learned using time-series data extracted from electronic health records. When extracting data for a clinical prediction task, several formulations exist, depending on how one chooses the time of prediction and the prediction horizon. In this paper, we show how…

2018-11-29abs ↗pdf ↗

Machine learning is bringing a paradigm shift to healthcare by changing the process of disease diagnosis and prognosis in clinics and hospitals. This development equips doctors and medical staff with tools to evaluate their hypotheses and hence make more precise decisions. Although most current research in the literatu…

2019-10-18abs ↗pdf ↗

New method targets relative risk heterogeneity in clinical trials.

problem Identifying treatment effects across subgroups with absolute risk differences.
method Modified causal forests using a novel node-splitting procedure based on relative risk.
result Relative risk causal forests can capture heterogeneity not detected by absolute risk methods.

Copula-based fusion improves breast cancer risk stratification.

problem Combining clinical and genomic risk scores using simple rules fails to capture their joint relationship.
method Used copulas to model the joint relationship between clinical and genomic risk scores.
result Copula-based fusion improves risk stratification, identifying subgroups with the worst prognosis.

FRESH combines patient-level and aggregate-level data for better clinical decision making.

problem Combining patient-level and aggregate-level data for clinical decision making.
method FRESH method that re-calibrates a patient-level model to match specified aggregate statistics.
result Unified data-efficient model for clinical decision making.

Study examines impact of fairness penalties on clinical risk prediction models.

problem Widespread health disparities in machine learning-guided clinical decision-making.
method Empirical study across multiple databases, outcomes, and sensitive attributes.
result Penalizing fairness violations nearly universally degrades model performance and fairness metrics.

The paper proposes a method to predict the performance of data-driven algorithms using surrogate models.

problem Improving the performance prediction of data-driven knowledge discovery algorithms.
method Surrogate-assisted performance prediction using evolutionary modeling of clinical pathways.
result The proposed approach provides interpretable prediction of algorithm performance and quality.

In this work we explored building automatic speech recognition models for transcribing doctor patient conversation. We collected a large scale dataset of clinical conversations (14,00014,000 hr), designed the task to represent the real word scenario, and explored several alignment approaches to iteratively improve data qua…

2017-11-20abs ↗pdf ↗

Framework integrates brain connectivity data for clinical predictions.

problem Predicting clinical outcomes from brain connectivity data.
method Structurally-regularized Dynamic Dictionary Learning (sr-DDL) and LSTM-ANN block.
result Framework outperforms state-of-the-art approaches in clinical outcome prediction.

Determining the optimal initial dose for warfarin is a critically important task. Several factors have an impact on the therapeutic dose for individual patients, such as patients' physical attributes (Age, Height, etc.), medication profile, co-morbidities, and metabolic genotypes (CYP2C9 and VKORC1). These wide range f…

2019-03-21abs ↗pdf ↗

Deep learning models (aka Deep Neural Networks) have revolutionized many fields including computer vision, natural language processing, speech recognition, and is being increasingly used in clinical healthcare applications. However, few works exist which have benchmarked the performance of the deep learning models with…

2017-10-23abs ↗pdf ↗

Transformers improve Alzheimer's disease progression prediction by accounting for irregular biomarker histories.

problem Difficult prediction of medium-horizon Alzheimer's disease progression due to tied clinical scores and irregular biomarker observations.
method Developed a residual gap-aware transformer that combines statistical reference with transformer-based residual learning.
result The proposed model reduces mean error and improves prediction-observation correlation compared to baseline models.

Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep learning models for the prediction of clinical outcomes using clinical notes. Ho…

2019-10-30abs ↗pdf ↗

Deep IDA integrates multi-view data to classify COVID-19 severity, identifying molecular signatures.

problem Understanding the complexity of COVID-19 severity from multi-view clinical and molecular data.
method Deep IDA learns nonlinear projections to maximize view associations and class separations, with feature ranking.
result Deep IDA outperforms other methods in classifying COVID-19 severity and identifies interpretable molecular signatures.

Hybrid Bayesian-conformal framework improves uncertainty quantification in healthcare predictions.

problem Jointly satisfying distribution-free coverage guarantees and risk-adaptive precision in clinical decision-making.
method Integrates Bayesian hierarchical random forests with group-aware conformal calibration, using posterior uncertainties to weight conformity scores.
result Achieves target coverage (94.3% vs 95% target) with adaptive precision, 21% narrower intervals for low-uncertainty cases.

Deep learning with medical data often requires larger samples sizes than are available at single providers. While data sharing among institutions is desirable to train more accurate and sophisticated models, it can lead to severe privacy concerns due the sensitive nature of the data. This problem has motivated a number…

2018-12-04abs ↗pdf ↗

Deep learning model creates patient representations for scalable EHR-based stratification.

problem Challenges in summarizing and representing patient data from EHRs prevent scalable stratification analysis.
method Unsupervised framework based on deep learning (ConvAE) using word embeddings, CNNs, and autoencoders.
result ConvAE significantly outperformed baselines in clustering diverse patient cohorts, identifying clinically relevant subtypes.